Keywords: Autoimmunity; primary immunodeficiency diseases; BÂ cells; T cells; AID; Activation-induced cytidine deaminase; AIHA; Autoimmune hemolytic anemia; AIRE; Autoimmune regulator; ALPS; Autoimmune lymphoproliferative disease; ANA; Anti-nuclear autoantibody; AP
مقالات ISI (ترجمه نشده)
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Keywords: ACP5; Acid phosphatase 5; ADAR1; Adenosine deaminase RNA-specific 1; AGS; Aicardi-Goutières syndrome; ALRs; AIM2-like receptors; AIM2; Absent in melanoma 2; ASC; Apoptosis-associated speck-like protein containing a CARD; CANDLE; Chronic atypical neutroph
Keywords: AIM2; absent in melanoma 2; AP-1; activating protein-1; APOBEC; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like; AZT; azidothymidine; CCCR5; C-C chemokine receptor type 5; CDK1; cyclin-dependent kinase 1; CXCR4; C-X-C chemokine receptor t
Interferon α subtypes in HIV infection
Keywords: AIDS; acquired immune deficiency syndrome; APOBEC3G; apolipoprotein B mRNA-editing enzyme-catalytic polypeptide-like 3G; ART; antiretroviral therapy; BLT; bone marrow-liver-thymus; Dpi; days post infection; HIV; human immunodeficiency virus; IDO; indoleam
Cloning, identification, and functional analysis of bone marrow stromal cell antigen-2 from sika deer (Cervus nippon)
Keywords: BST-2; bone marrow stromal cell antigen 2; IFNs; interferons; APOBEC3G; apolipoprotein B mRNA-editing enzyme, catalytic polypeptide-like 3G; TRIM5α; tripartite motif 5-alpha; SAMHD1; SAM and HD domain containing deoxynucleoside triphosphate triphosphohyd
The role of SAMHD1 expression and its relation to HIV-2 (Vpx) gene production
Keywords: HIV-1; HIV-2; SAMHD1; Vpx protein; Macrophages;
DNA damage response signaling does not trigger redistribution of SAMHD1 to nuclear foci
Keywords: SAMHD1; DNA double-strand break (DSB) induction; Alternative translation initiation site (TIS);
Fish SAMHD1 performs as an activator for IFN expression
Keywords: SAMHD1; Innate immune; PRR; STING; Fish;
SAMHD1 deficient human monocytes autonomously trigger type I interferon
Keywords: SAMHD1; IFN; AGS; TBK1-IRF3; ISGs;
ADAR1 and PKR, interferon stimulated genes with clashing effects on HIV-1 replication
Keywords: ADAR1; adenosine deaminase acting on RNA 1; AGS; Aicardi-Goutières syndrome; APOBEC3; apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3; ds; double-stranded; dsRBD; dsRNA binding domains; eIF2α; translation initiation factor2; HIV-1; hum
Evaluation of resistance to HIV-1 infection ex vivo of PBMCs isolated from patients with chronic myeloid leukemia treated with different tyrosine kinase inhibitors
Keywords: HIV-1; Viral reservoir; SAMHD1; Src tyrosine kinases; Chronic myeloid leukemia;
Type I interferon and HIV: Subtle balance between antiviral activity, immunopathogenesis and the microbiome
Keywords: IFN; interferon; ISGs; IFNstimulated genes; HCV; hepatitis C virus; IL-10; interleukin-10; PDL-1; programmed death-ligand 1; LCMV; lymphocytic choriomeningitis virus; IFNAR; IFNA receptor; IRFs; IFN regulatory factors; pDCs; plasmacytoid dendritic cells;
MicroRNA-181 contributes to downregulation of SAMHD1 expression in CD4+ T-cells derived from Sèzary syndrome patients
Keywords: SAMHD1; sterile alpha motif and HD domain containing protein 1; CTCL; cutaneous T-cell lymphoma; SS; Sézary syndrome; miR; microRNA; CLL; chronic lymphocytic leukemia; AGS; Aicardi-Goutierres syndrome; Cutaneous T-cell lymphoma; MicroRNA; SAMHD1; Sèza
SAMHD1 is active in cycling cells permissive to HIV-1 infection
Keywords: CRISPR; Genome editing; SAMHD1; dNTPase activity;
SAMHD1, the Aicardi-Goutières syndrome gene and retroviral restriction factor, is a phosphorolytic ribonuclease rather than a hydrolytic ribonuclease
Keywords: SAMHD1; Phosphorolytic activity; Exoribonuclease;
HD domain of SAMHD1 influences Vpx-induced degradation at a post-interaction step
Keywords: SAMHD1; Vpx; HD domain; Virus-host interaction; Virus-induced proteasomal degradation; SAMHD1GG; SAMHD1 from chicken (Gallus gallus); SAMHD1HS; SAMHD1 from human (Homo sapiens);
Low dNTP levels are necessary but may not be sufficient for lentiviral restriction by SAMHD1
Keywords: SAMHD1; HIV-1; SIV; dATP; dNTPase; Nuclease; Restriction;
Inhibition of hepatitis B virus replication by a dNTPase-dependent function of the host restriction factor SAMHD1
Keywords: SAMHD1; HBV restriction; dNTPase; cccDNA;
Modulation of LINE-1 retrotransposition by a human SAMHD1 polymorphism
Keywords: SAMHD1; LINE-1; SNPs; Retrotransposition; Restriction; HIV-1
Branchial transcriptional responses of spotted scat, Scatophagus argus, to acute hypo-osmotic stress
Keywords: SW; salt water; FW; fresh water; SSH; suppression subtractive hybridization; arf1; ADP-ribosylation factor 1; creb3l4; cyclic AMP-responsive element-binding protein 3-like 4; evi5l; EVI5-like protein; fat2; protocadherin fat 2; tfr2; transferrin receptor
SAMHD1 controls cell cycle status, apoptosis and HIV-1 infection in monocytic THP-1 cells
Keywords: SAMHD1; Monocytic cells; Gene knockout; HIV-1; dNTP; Restriction; Cell cycle; Apoptosis;
Dasatinib inhibits HIV-1 replication through the interference of SAMHD1 phosphorylation in CD4+ T cells
Keywords: HIV-1 reservoir; Dasatinib; SAMHD1; CD4+ T lymphocytes; Chronic myeloid leukemia
Pathways controlling dNTP pools to maintain genome stability
Keywords: BER; base excision repair; CDA; cytidine deaminase; MMR; mis-match repair; MTH; MutT homologue; MUTYH; MutY homologue; Nudix; nucleoside diphosphate linked to some other moiety, X; NUDT; Nudix-type; OGG1; 8-oxoguanine glycosylase; ROS; reactive oxygen spe
Understanding the molecular manipulation of DCAF1 by the lentiviral accessory proteins Vpr and Vpx
Keywords: Vpr; Vpx; DCAF1; HIV; SIV; SAMHD1; DDB1; VprBP; Degradation; Interaction;
Determinants for degradation of SAMHD1, Mus81 and induction of G2 arrest in HIV-1 Vpr and SIVagm Vpr
Keywords: HIV-1; SIV; Vpr; Mus81; Agm; SAMHD1; DCAF1; G2 arrest; Ubiquitination; MLN4924;
Differential regulatory activities of viral protein X for anti-viral efficacy of nucleos(t)ide reverse transcriptase inhibitors in monocyte-derived macrophages and activated CD4+ T cells
Keywords: Vpx; SAMHD1; Antiretrovirals; SIV; RT-SHIV; HIV-1;
Disease specific therapies in leukodystrophies and leukoencephalopathies
Keywords: X-ALD; X-linked Adrenoleukodystrophy; AGS; Aicardi-Goutières Syndrome; CSF; cerebrospinal fluid; IFNα; α-interferon; RNA; ribonucleic acid; DNA; deoxyribonucleic acid; SLE; systemic lupus erythematosus; AxD; Alexander disease; GFAP; growth factor ass
Mutational analysis of HIV-2 Vpx shows that proline residue 109 in the poly-proline motif regulates degradation of SAMHD1
Keywords: HIV-2; Vpx; SAMHD1; Poly-proline;
Analysis of protein kinase C theta inhibitors for the control of HIV-1 replication in human CD4+ T cells reveals an effect on retrotranscription in addition to viral transcription
Keywords: HIV-1; Protein kinase C theta; SAMHD1; Antiretroviral therapy; Latent reservoir
SAMHD1 is down regulated in lung cancer by methylation and inhibits tumor cell proliferation
Keywords: SAMHD1; Lung adenocarcinoma; dNTP; Cell proliferation;
Inhibition of Hepatitis B virus replication by SAMHD1
Keywords: SAMHD1; HBV; IFN-α; Liver cell;
Crosstalk between Mycobacterium tuberculosis and the host cell
Keywords: AC; adenylyl cyclase; AKAP7; A-kinase anchor protein 7 isoform gamma; AM; alveolar macrophage; ATP; adenosine triphosphate; BCG; Bacille Calmette-Guérin; cAMP; cyclic adenosine monophosphate; CD1; cluster of differentiation 1; c-di-AMP; cyclic-di-adeno
Effects of human SAMHD1 polymorphisms on HIV-1 susceptibility
Keywords: SAMHD1; SNPs; HIV-1; Vpx; dNTPs; LINE-1
Molecular cloning and characterizations of porcine SAMHD1 and its roles in replication of highly pathogenic porcine reproductive and respiratory syndrome virus
Keywords: SAMHD1; Porcine; Antiviral effect; HP-PRRSV;
Contribution of SAM and HD domains to retroviral restriction mediated by human SAMHD1
Keywords: SAMHD1; HIV-1; HD domain; Restriction; dNTPase; RNA binding;
Innate immune processes in lupus erythematosus
Keywords: Lupus; Cytokines; TREX1; RNase-H2; SAMHD1
Intracellular nucleotide levels and the control of retroviral infections
Keywords: Retroviruses; Reverse transcriptase; dNTP pools; Nondividing Cells; SAMHD1; Vpx
The importance of becoming double-stranded: Innate immunity and the kinetic model of HIV-1 central plus strand synthesis
Keywords: Central polypurine tract (cPPT); Central DNA flap; HIV-1; Lentivirus; Restriction factor; APOBEC3G; SAMHD1; Reverse transcription; Innate immunity; Nucleic acid sensors
Les syndromes lupiques monogéniques
Keywords: Génétique; Lupus érythémateux disséminé; Pédiatrie; Complément; Déficit immunitaire; Fas; FasL; Phosphatase acide tartrate résistante; SAMHD1; ALPSGenetics; Systemic lupus erythematosus; Pediatrics; Complement; Immunodeficiency; Fas; FasL; TRAP; SAMHD1; A