Keywords: سرین هیدروکسی متیل ترانسفراز; One carbon metabolism; Cancer metabolism; Serine hydroxymethyltransferase; Isozymes; Enzyme inhibition; Pyrazolopyran scaffold; Pyridoxal 5â²-phosphate; PLP; serine hydroxymethyltransferase; SHMT; cytosolic SHMT; SHMT1; mitochondrial SHMT; SHMT2; Escheri
مقالات ISI سرین هیدروکسی متیل ترانسفراز (ترجمه نشده)
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Keywords: سرین هیدروکسی متیل ترانسفراز; CH2THF; 5,10-methylene tetrahydrofolate; DCD; dCTP deaminase; DCD-DUT; bifunctional dCTP deaminase-dUTPase; DUT; dUTPase; DHF; dihydrofolate; DHFR; dihydrofolate reductase; DHFR-TS; bifunctional dihydrofolate reductase - thymidylate synthase; FAD; f
Computational elucidation of novel antagonists and binding insights by structural and functional analyses of serine hydroxymethyltransferase and interaction with inhibitors
Keywords: سرین هیدروکسی متیل ترانسفراز; SHMT; Serine hydroxymethyltransferase; Ld; Leishmania donovani; PLP; Pyridoxal phosphate; THF; Tetrahydrofolate; TS; Thymidylate synthase; PDB; Protein Data Bank; NCBI; National Center for Biotechnology Information; DOPE; Discrete optimized protein energy
Folate and microRNA: Bidirectional interactions
Keywords: سرین هیدروکسی متیل ترانسفراز; 1CM; One-carbon metabolism; 5-MTHF; methyltetrahydrofolate; Aβ; amyloid-β protein; APP; amyloid precursor protein; DHFR; dihydrofolate reductase; MTHFR; methylenetetrahydrofolate reductase; MTR; methionine synthase; NAFLD; Non-alcoholic fatty liver dise
Human and Plasmodium serine hydroxymethyltransferases differ in rate-limiting steps and pH-dependent substrate inhibition behavior
Keywords: سرین هیدروکسی متیل ترانسفراز; Serine hydroxymethyltransferase; Pyridoxal 5â²-phosphate; Tetrahydrofolate; Ligand binding; Rapid-quench flow; Substrate inhibition; Rate determining step;
Differential 3-bromopyruvate inhibition of cytosolic and mitochondrial human serine hydroxymethyltransferase isoforms, key enzymes in cancer metabolic reprogramming
Keywords: سرین هیدروکسی متیل ترانسفراز; SHMT; serine hydroxymethyltransferase; SHMT1; cytosolic SHMT; SHMT2; mitochondrial SHMT; 3BP; 3-bromopyruvate; PLP; pyridoxal 5â²-phosphate; H4PteGlu; tetrahydropteroylglutamate; Cancer metabolic reprogramming; Serine hydroxymethyltransferase; Isozymes;
A structural model for FOXRED1, an FAD-dependent oxidoreductase necessary for NADH: Ubiquinone oxidoreductase (complex I) assembly
Keywords: سرین هیدروکسی متیل ترانسفراز; CPS; carbamoyl phosphate synthase; DAO; d-amino acid oxidase; DMGDH; dimethylglycine dehydrogenase; DMGO; dimethylglycine oxidase; FOXRED; FAD-dependent oxidoreductase; HADHA; hydroxyacyl dehydrogenase; MDH; malate dehydrogenase; MSOX; monomeric sarcosine
Proteomic analysis of the effects of gibberellin on increased fruit sink strength in Asian pear (Pyrus pyrifolia)
Keywords: سرین هیدروکسی متیل ترانسفراز; ACA; acetyl-CoA C-acetyltransferase; ACX; medium chainacyl-coenzyme a oxidase peroxisomal; SHMT; serine hydroxymethyltransferase; MATS; -adenosylmethionine synthetase; FDH; formate dehydrogenase; OEE; oxygen-evolving enhancer protein; γCA; gamma carbonic
Metabolic flux analysis of the halophilic archaeon Haladaptatus paucihalophilus
Keywords: سرین هیدروکسی متیل ترانسفراز; 13C-assisted metabolism analysis; Glycine biosynthesis; Halophilic archaea; Isoleucine biosynthesis; Lysine biosynthesis; SHMT; Serine hydroxymethyltransferase; TA; threonine aldolase; GCS; glycine cleavage system; TCA; tricarboxylic acid; THF; tetrahydro
MYC and metabolism on the path to cancer
Keywords: سرین هیدروکسی متیل ترانسفراز; 2-DG; 2-deoxyglucose; 4E-BP; eIF4E-binding protein; 5,10-methylene THF; 5,10-methylenetetrahydrofolate; ACC; acetyl-CoA carboxylase; ACLY; ATP-citrate lyase; AMPK; AMP-activated protein kinase; ATP; adenosine triphosphate; ChIP-seq; chromatin immunoprecip
Nucleotide biosynthesis arrest by silencing SHMT1 function via vitamin B6-coupled vector and effects on tumor growth inhibition
Keywords: سرین هیدروکسی متیل ترانسفراز; Serine hydroxymethyltransferase; Vitamin B6; Poly(ester amine); Membrane carrier; siRNA
Structural stability of cold-adapted serine hydroxymethyltransferase, a tool for β-hydroxy-α-amino acid biosynthesis
Keywords: سرین هیدروکسی متیل ترانسفراز; SHMT; serine hydroxymethyltransferase; PLP; pyridoxal-5â²-phosphate; H4PteGlu; tetrahydropteroylglutamate; piSHMT; SHMT from Psychromonas ingrahamii; ecSHMT; SHMT from Escherichia coli; Psychrophilic serine hydroxymethyltransferase; Protein stability; Co
Mitochondrial DNA methylation as a next-generation biomarker and diagnostic tool
Keywords: سرین هیدروکسی متیل ترانسفراز; AD; Alzheimer disease; AIMs; amplification of inter-methylated sites; ALS; amyotrophic lateral sclerosis; ChIP; chromatin immunoprecipitation; CTH; cystathionine γ-lyase; CHARM; comprehensive high-throughput arrays for relative methylation; CBS; cystathi
Genetic variation in folate metabolism is not associated with cognitive functioning or mood in healthy adults
Keywords: سرین هیدروکسی متیل ترانسفراز; APOE; apolipoprotein E; CST; Concept Shifting Test; FACIT; Folic Acid and Carotid Intima-Media Thickness study; LDST; Letter-Digit Substitution Test; MAAS; Maastricht Aging Study; MTHFR; 5,10-methylenetetrahydrofolate reductase; SCLdep; depression subscal
PLP-dependent enzymes as potential drug targets for protozoan diseases
Keywords: سرین هیدروکسی متیل ترانسفراز; Serine hydroxymethyltransferase; Aspartate transaminase; Cysteine desulfurase; Ornithine decarboxylase; Cysteine synthase; Antiprotozoan therapy
Immobilization of PLP-dependent enzymes with cofactor retention and enhanced stability
Keywords: سرین هیدروکسی متیل ترانسفراز; PLP-dependent enzymes; Immobilization; Serine hydroxymethyltransferase; Alanine racemase; Aspartate aminotransferase
Structural adaptation of serine hydroxymethyltransferase to low temperatures
Keywords: سرین هیدروکسی متیل ترانسفراز; Psychrophile; Serine hydroxymethyltransferase; Flexibility; Polarity; Electrostatic potential; Molecular evolution; Pyridoxal-5â²-phosphate;
Characterization of Plasmodium falciparum serine hydroxymethyltransferase-A potential antimalarial target
Keywords: سرین هیدروکسی متیل ترانسفراز; SHMT; serine hydroxymethyltransferase; PfSHMT; Plasmodium falciparum serine hydroxymethyltransferase; Pv; P. vivax; dTMP; deoxythymidine 5â²-monophosphate; H4folate; (6RS)-tetrahydrofolate; CH2-H4folate; 5,10-methylenetetrahydrofolate; CH3-H4folate; 5-me
Cloning and characterization of Plasmodium vivax serine hydroxymethyltransferase
Keywords: سرین هیدروکسی متیل ترانسفراز; Pf, Plasmodium falciparum; Pv, P. vivax; DHFR, dihydrofolate reductase; TS, thymidylate synthase; SHMT, serine hydroxymethyltransferase; PLP, pyridoxal phosphate; c, cytosol; mt, mitochondria; bp, base pairPlasmodium vivax; Serine hydroxymethyltransferase
Effect of vitamin B6 availability on serine hydroxymethyltransferase in MCF-7 cells
Keywords: سرین هیدروکسی متیل ترانسفراز; Serine hydroxymethyltransferase; Vitamin B6; Pyridoxal-phosphate; One-carbon metabolism; Homocysteine; Folate
Molecular cloning and biochemical characterization of Leishmania donovani serine hydroxymethyltransferase
Keywords: سرین هیدروکسی متیل ترانسفراز; Serine hydroxymethyltransferase; Leishmania donovani; Folate; Nucleotide biosynthesis
Cloning and structural analysis of Mycobacterium leprae serine hydroxymethyltransferase
Keywords: سرین هیدروکسی متیل ترانسفراز; Serine hydroxymethyltransferase; Pyridoxyl-5′-Phosphate; Catalytic efficiency; Fluorescence; Circular dichroism; Protein folding
Cloning, expression, purification, and characterization of zebrafish cytosolic serine hydroxymethyltransferase
Keywords: سرین هیدروکسی متیل ترانسفراز; Serine hydroxymethyltransferase; Folate; One-carbon metabolism; B6 enzyme; Zebrafish
Properties of human and rabbit cytosolic serine hydroxymethyltransferase are changed by single nucleotide polymorphic mutations
Keywords: سرین هیدروکسی متیل ترانسفراز; Serine hydroxymethyltransferase; Gene polymorphism; Single nucleotide polymorphism; One-carbon metabolism; Tetrahydrofolate; B6 enzyme; Folic acid; Homocysteine; Folate binding affinity; Site-directed mutagenesis;