Keywords: AFM; atomic force microscopy; AIBN; azobisisobutyronitrile; AN; acrylonitrile; ARGET; activators regenerated by electron transfer; ATRP; atom transfer radical polymerization; ATRA; atom transfer radical addition; BA; n-butyl acrylate; BIPE; bis(2-iodoprop
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Keywords: 2,4-D; 2,4-dichlorophenoxyacetic acid; 4-VP; 4-vinylpyridine; AAm; acrylamide; AIBN; azobisisobutyronitrile; ATRA; atom transfer radical addition; ATRP; atom transfer radical polymerization; BDC; benzyl diethyldithiocarbamate; BET; Brunauer-Emmett-Tel
Dampening of the bone formation response following repeat dosing with sclerostin antibody in mice is associated with up-regulation of Wnt antagonists
Keywords: BMD; bone mineral density; Col1a1; collagen, type I, alpha 1; Dkk; Dickkopf; DXA; dual-energy X-ray absorptiometry; Eif3f; eukaryotic translation initiation factor 3, subunit F; FRZB; Frizzled related protein; LRP; low density lipoprotein receptor-related
The WNT signaling pathways in wound healing and fibrosis
Keywords: ADP; adenosine diphosphate; APC; adenomatosis polyposis coli; CBP; cyclic AMP response element binding protein; CCL4; carbon tetrachloride; CK-1; casein kinase 1; DKK; dickkopf; EVI; evenness interrupted; FZD; frizzled; GSK-3; glycogen synthase kinase 3;
WNT receptor signalling in lung physiology and pathology
Keywords: ABC; active β-catenin/non-phosphorylated β-catenin; APC; adenomatous polyposis coli; ATI; alveolar epithelial type I cell; ATII; alveolar epithelial type II cell; AXIN; axis inhibition protein; CBR2; carbonyl reductase 2; CK1; casein kinase 1; CELSR1; c
Comparative analysis of the neurula transcriptomes of two species of flatfishes: Platichthys stellatus and Paralichthys olivaceus
Keywords: BMP; Bone Morphogenetic Protein; BMPR; Bone Morphogenetic Protein Receptor; BLAST; Basic Local Alignment Search Tool; ERBB; Erb-b2 Receptor Tyrosine Kinase; FGF; Fibroblast Growth Factor; FGFR; Fibroblast Growth Factor Receptor; FZ; Frizzled; HOXB1B; Home
Analysis of the expression of the Wnt family of proteins and its modulatory role on cytokine expression in non activated and activated astroglial cells
Keywords: CNS; central nervous system; BBB; blood brain barrier; Fz; Frizzled; ROR; receptor tyrosine kinase-like orphan receptor; PTK7; protein tyrosine kinase 7; PCP; planar cell polarity; Wif; Wnt inhibitory factor; Dkk; Dickkopf; sFRP; secreted Frizzled-related
Single nucleotide variations in the Wnt antagonist sFRP3 (rs7775 & rs288326) and sFRP4 (rs1802073 & 1802074) genes and their association with lung cancer risk in North Indians
Keywords: LRP; LDL-receptor related protein; GSK-3β; glycogen synthase kinase-3β; Dvl; dishevlled; TCR; T-cell receptor; LEF; lymphoid enhancing factor; sFRP; Secreted frizzled related protein; VEGF-A; vascular endothelial growth factor-A; MMP7; matrix metallopro
Complexity of the Wnt/βâcatenin pathway: Searching for an activation model
Keywords: APC; adenomatous polyposis coli; BCL-9; B-cell lymphoma 9; BMPs; bone morphogenetic proteins; CARM; coactivator-associated arginine methyltransferase; CBP; CREB-binding protein; CK1α; casein kinase 1α; CRD; Cysteine-Rich Domain; DIX; Dishevelled interac
sFRP-mediated Wnt sequestration as a potential therapeutic target for Alzheimer's disease
Keywords: Alzheimer's disease; Wnt; sFRP; Neurodegeneration;
Wnt, Frizzled, and sFRP gene expression patterns during gastrulation in the starfish Patiria (Asterina) pectinifera
Keywords: Starfish; Embryo; Expression pattern; Wnt; Frizzled; sFRP
Alteration of canonical and non-canonical WNT-signaling by crystalline silica in human lung epithelial cells
Keywords: ACTA2; Actin, alpha, smooth muscle; ANGPTL4; Angiopoietin-like 4; ANOVA; Analysis of variance; AXIN; Axis inhibition protein; BMP; Bone morphogenic protein; BMPR1B; BMP receptor 1B; CACNA2D3; Calcium channel, voltage-dependent, alpha 2/delta subunit 3; CC
“Fibrous nests” in human hepatocellular carcinoma express a Wnt-induced gene signature associated with poor clinical outcome
Keywords: α-SMA; alpha smooth muscle actin; DKK; Dickkopf; ECM; extracellular matrix; FNH; focal nodular hyperplasia; FZD; frizzled; GSE; gene expression series; GSK3B; glycogen synthase kinase 3 beta; HCC; hepatocellular carcinoma; iPS cells; induced pluripotent
Loss of Frzb and Sfrp1 differentially affects joint homeostasis in instability-induced osteoarthritis
Keywords: Cartilage; Osteoarthritis; Wnt; SFRP; FRZB; Subchondral bone
Number and brightness analysis of sFRP4 domains in live cells demonstrates vesicle association signal of the NLD domain and dynamic intracellular responses to Wnt3a
Keywords: Wnt; sFRP; Cysteine-rich domain; Netrin-like domain; Protein aggregates; Live cell imaging;
ROBO3 promotes growth and metastasis of pancreatic carcinoma
Keywords: Pancreatic cancer; ROBO3; Invasion; Metastasis; miR-383; EMT; endothelial to mesenchymal transition; SFRP; Secreted Frizzled Related Protein; PDAC; pancreatic ductal adenocarcinoma; TGF-β; transforming growth factor-β; miRNAs; MicroRNAs;
Wnt/β-catenin signaling in heart regeneration
Keywords: Wnt; Beta-catenin; Cardiomyocyte; sFrp; Regeneration; Heart; Fibrosis; Hypertrophy; Zebrafish;
β-Catenin Signaling and Roles in Liver Homeostasis, Injury, and Tumorigenesis
Keywords: WNT; β-Catenin; E-Cadherin; Liver Fibrosis; NASH; HCC; Liver Tumors; AJ; adherens junction; APC; adenomatous polyposis coli gene product; FNH; focal nodular hyperplasia; FOXO; forkhead box protein O; GS; glutathione synthetase; GSK3β; glycogen synthase
Hyperpolarized 3He diffusion MRI and histology of secreted frizzled related protein-1 (SFRP1) deficient lungs in a Murine model
Keywords: SFRP1; secreted frizzled receptor protein-1; HP; HYPERPOLARIZED; Lm; mean linear intercept; WT; wild-type; KO; knockout; Hyperpolarized gas MRI; Helium-3 MRI; ADC; SFRP; Secreted frizzled related protein; Lungs; Knockout; Embryogenesis;
Dissipation analysis in SFRP structural samples: Thermomechanical analysis and comparison to numerical simulations
Keywords: SFRP; Thermal measurement; Dissipated energy field; Structural sample
Biomarkers for virus-induced hepatocellular carcinoma (HCC)
Keywords: AFP; α-fetoprotein; HCC; hepatocellular carcinoma; HBV/HCV; Hepatitis B virus/C virus; DCP; des-gamma-carboxy prothrombin; GP73; Golgi protein; GPC3; Glypican-3; CD10; Cluster of differentiation 10; CD36; Cluster of differentiation 36; SAGE; serial analy
Dynamic expression of secreted Frizzled-related protein 3 (sFRP3) in the developing mouse spinal cord and dorsal root ganglia
Keywords: CRD; cysteine-rich domain; CNS; central nervous system; dI; dorsal interneuron; dp1-6; dorsal progenitor domains 1-6; DRG; dorsal root ganglia; E9.5-18.5; Embryo day 9.5-18.5; FZD; Frizzled family of Wnt receptor; ISH; in situ hybridization; P0-
Wnt signaling in liver fibrosis: Progress, challenges and potential directions
Keywords: Liver fibrosis; Wnt signaling; Canonical Wnt signaling pathway; Hepatic stellate cell; Myofibroblastic transdifferentiation; HSCs; hepatic stellate cells; GFAP; glial fibrillary acidic protein; a-SMA; a-smooth muscle actin; TRAIL; tumor necrosis factor-re
Cripto-1 enhances the canonical Wnt/β-catenin signaling pathway by binding to LRP5 and LRP6 co-receptors
Keywords: TDGF-1; teratocarcinoma-derived growth factor-1; CFC; Cripto-1/FRL1/Cryptic; GPI; glycosylphosphatidylinositol; TGF-β; transforming growth factor-β; GDF; growth differentiation factor; Tcf; T-cell factor; Fz; frizzled; LRP; low-density lipoprotein recep
Wnt signaling pathway in rheumatoid arthritis, with special emphasis on the different roles in synovial inflammation and bone remodeling
Keywords: RA; rheumatoid arthritis; FLS; fibroblast-like synoviocytes; ACPA; anti-citrullinated peptide antibody; DKK1; dickkopf-1; 11β-HSD1; 11beta-hydroxysteroid dehydrogenase type 1; PADI4; peptidylarginine deiminase-4; hTERT; human telomerase reverse transcrip
Fast prediction of the Wöhler curve from heat build-up measurements on Short Fiber Reinforced Plastic
Keywords: PA66GF50; SFRP; Fatigue; Heat build-up; Energetic criterion
Frizzled7 as an emerging target for cancer therapy
Keywords: ALL; Acute lymphoblastic leukemia; APC; Adenomatous polyposis coli; CamKII; Calmodulin kinase II; Cthrc1; Collagen triple helix repeat containing protein; CK1; Caseine kinase 1; CTNNB1; β-catenin gene; CRD; Cysteine rich domain; CSC; Cancer stem cells; D
Multi-layered environmental regulation on the homeostasis of stem cells: The saga of hair growth and alopecia
Keywords: Regeneration; Niche; Macro-environment; Stem cell; Bmp; Sfrp; Dkk; Hair; Alopecia; Adipose cell
Adipocyte-secreted factors increase osteoblast proliferation and the OPG/RANKL ratio to influence osteoclast formation
Keywords: ALP; Alkaline phosphatase; bFGF; Basic fibroblast growth factor; BMI; Body mass index; BMD; Bone mineral density; CM; Control medium; DKK; Dickkopf; EGF; Epidermal growth factor; FCCM; Fat-cell conditioned-medium; FGFR1; Fibroblast growth factor receptor
Calcificaciones vasculares en pacientes con insuficiencia renal crónica
Keywords: Calsificación vascular; proteína; Matrix Gla Fetuin A; proteina2 morfogenética del hueso; 2-Cbaf1; gremlin; Dkk1; sFRP; señal WntVascular calcification; matrix gla protein; fetuin A; bone morphogenetic protein 2; Cbaf1; gremlin; Dkk1; sFRP; Wnt signal
Dorsal-Ventral patterning: Crescent is a dorsally secreted Frizzled-related protein that competitively inhibits Tolloid proteases
Keywords: BMP signaling; Wnt signaling; Tolloid; Chordin; sFRP; Morphogenetic field; Sizzled; Ogon; Crossveinless-2;
Estrogenic environmental chemicals and drugs: Mechanisms for effects on the developing male urogenital system
Keywords: AR; androgen receptor; Ar; androgen receptor gene; Bmp4; bone morphogenetic protein 4; BPA; bisphenol A; Capn6; Calpain; Cyp7b1; cytochrome P450, family 7, subfamily b, polypeptide 1; DES; diethylstilbestrol; DHT; 5α-dihydrotestosterone; EGF; epidermal g
Expression profile of WNT, FZD and sFRP genes in human hematopoietic cells
Keywords: Wnt; Frizzled; sFRP; Expression; Bone marrow;
Transcriptional down-regulation of the Wnt antagonist SFRP1 in haematopoietic cells of patients with different risk types of MDS
Keywords: MDS; Acute leukaemia; SFRP; Wnt signalling; Promoter methylation; Pyrosequencing
MSX1 induces the Wnt pathway antagonist genes DKK1, DKK2, DKK3, and SFRP1 in neuroblastoma cells, but does not block Wnt3 and Wnt5A signalling to DVL3
Keywords: DKK; MSX1; Neuroblastoma; SFRP; Wnt
Stimuli-responsive amphiphilic (co)polymers via RAFT polymerization
Keywords: 2VP; 2-vinylpyridine; 4VP; 4-vinylpyridine; AA; acrylic acid; AAL; N-acryloylalanine; AGA; acryloyl glucosamine; A-Hyp-OH; N-acryloyl-4-trans-l-proline; A-Hyp-Ome; N-acryloyl-4-trans-l-proline methyl ester; AIBN; 2,2â²-azobisisobutyronitrile; AM; acrylam
sFRP1 promoter methylation is associated with persistent Philadelphia chromosome in chronic myeloid leukemia
Keywords: Chronic myeloid leukemia; Imatinib; Cytogenetics; sFRP; Methylation; Wnt signaling
Wnt modulators, SFRP-1, and SFRP-2 are expressed in osteoblasts and differentially regulate hematopoietic stem cells
Keywords: Hematopoietic stem cells; Secreted frizzled-related protein; SFRP; Wnt; Self-renewal; Osteoblast
BMP/Wnt antagonists are upregulated by dexamethasone in osteoblasts and reversed by alendronate and PTH: Potential therapeutic targets for glucocorticoid-induced osteoporosis
Keywords: Follistatin; Dan; sFRP; Dexamethasone; Alendronate; PTH; Osteoblast;
Inhibition of canonical Wnt signaling promotes gliogenesis in P0-NSCs
Keywords: bFGF; basic fibroblast growth factor; Dkk; dickkopf; EGF; epidermal growth factor; EGFP; enhanced green fluorescent protein; IRES; internal ribosome entry site; LEF; lymphoid enhancer-binding factor; NSCs; neurospheres; P; postnatal day; sFRP; secreted fr
Epigenetic dysregulation of secreted Frizzled-related proteins in multiple myeloma
Keywords: Wnt pathway; SFRP; Epigenetics; Multiple myeloma; DNA methylation
Comprehensive expression analysis of all Wnt genes and their major secreted antagonists during mouse limb development and cartilage differentiation
Keywords: Limb development; Chondrogenesis; Growth plate; Wnt; Sfrp; Frzb; Dkk; Wisp; Wif1
Expression of the chick Sizzled gene in progenitors of the cardiac outflow tract
Keywords: Primary heart fields; Anterior heart field; Chick embryo; Sizzled; Crescent; Sfrp; Outflow tract; Cardiac development
Application of micromechanical models for elasticity and failure to short fibre reinforced composites. Numerical implementation and experimental validation
Keywords: Failure criterion; Composites; Finite element analysis; Fibre orientation; Anisotropy; SFRP
Wnt3a binds to several sFRPs in the nanomolar range
Keywords: SPR, surface plasmon resonance; ES cells, mouse embryonic stem cells; EB, embryoid bodiesWnt; sFRP; SPR; ES cells; β-Catenin; Frizzled; Canonical Wnt signaling
Aberrant Crypt Foci: What We Know and What We Need to Know
Keywords: ACF; aberrant crypt foci; APC; adenomatous polyposis coli; CRC; colorectal carcinoma; FAP; familial adenomatous polyposis; HMCC; high-magnification chromoscopic colonoscopy; SFRP; secreted frizzled-related proteins;
The activation of beta-catenin by Wnt signaling mediates the effects of histone deacetylase inhibitors
Keywords: APC; adenomatous polyposis coli; CRC; colorectal carcinoma; Dkk1; Dickkopf-1; EGFP; enhanced green fluorescent protein; GSK-3beta; glycogen synthase-kinase 3beta; BCT; beta-catenin-Tcf; HDACi; histone deacetylase inhibitors; LRP; low-density lipoprotein r
Duplicate sfrp1 genes in zebrafish: sfrp1a is dynamically expressed in the developing central nervous system, gut and lateral line
Keywords: Blastoderm; CNS; Danio rerio; Ear; Endoderm; Enhancer trap; Eye; Fin-bud; Frizzled; FrzA; Gastrula; Gut; Hindbrain; Interneuromast; Lateral line; Midbrain; Neuroectoderm; Neuromast; Paraxial mesoderm; Presomitic; Primordium; Pronephric duct; Pronephros; S
Lens induction in vertebrates: Variations on a conserved theme of signaling events
Keywords: ANP; anterior neural plate; BMP; bone morphogenetic protein; ERK; extracellular signal related kinase; FGF; fibroblast growth factor; Hh; hedgehog; HH; Hamburger and Hamilton stage; NCC; neural crest cell; OV; optic vesicle; PLE; presumptive lens ectoderm
Cloning and embryonic expression of five distinct sfrp genes in the zebrafish Danio rerio
Keywords: Secreted frizzled-related protein; sFRP; Tlc; Sizzled; Wnt antagonist; Anterior neural plate; Telencephalon; Eyes; Hypothalamus; Midbrain; Tegmentum; Tectum; Hindbrain; Spinal cord; Otic vesicles; Lateral line; Somite; Adaxial cells; Gut; Fins