Keywords: تماشای; Shikonin; Hyperglycemia; NRK-52E cell; Diabetic nephropathy; Oxidative stress;
مقالات ISI تماشای (ترجمه نشده)
مقالات زیر هنوز به فارسی ترجمه نشده اند.
در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Keywords: تماشای; Streptococcus Pneumoniae; Pneumolysin; Shikonin; Virulence; Genotoxicit; Lethal pneumonia;
Keywords: تماشای; Shikonin; β-Cyclodextrin; Multiwalled carbon nanotubes; Modified electrode; Electrochemical detection
Keywords: تماشای; Shikonin; Osteoarthritis; Interleukin-1β; Matrix metallopeptidases; Chondrocytes; NF-κB;
Keywords: تماشای; αSMA; alpha-smooth muscle actin; Bcl-2; B-cell lymphoma 2; Caspases; Cysteine-dependent aspartate-directed proteases; COL1A1; collagen type Ð gene; COL3A1; collagen type Ш gene; DAPI; 4â²,6-diamidino-2-phenylindole; DMEM; Dulbecco's Modified Eagleâ
Keywords: تماشای; Alkannin; Shikonin; Oxime derivatives; Antitumor activity;
Keywords: تماشای; Apoptosis; Gastric cancer; Necrosis; Shikonin
Keywords: تماشای; Shikonin; Lipopolysaccharide (LPS); Acute lung injury (ALI); Anti-inflammatory; Nuclear factor-kappaB (NF-κB);
Keywords: تماشای; RIP1; receptor interacting protein 1; RIP3; receptor interacting protein3; SKN; shikonin; TNFα; tumor necrosis factor alpha; ROS; reactive oxygen species; Nec-1; necrostatin-1; zVAD; benzyloxycarbonyl-Val-Ala-Asp (OMe) fluoromethylketone; Shikonin; Progr
Keywords: تماشای; Acute pancreatitis; Shikonin; Inflammation; NF-κB; Cytokine;
Keywords: تماشای; Shikonin; Alkannin; Solubilization; Cyclodextrin; Apoptosis
Shikonin exerts anti-inflammatory effects in LPS-induced mastitis by inhibiting NF-κB signaling pathway
Keywords: تماشای; Shikonin; LPS; Mastitis; Nuclear factor-κB; Pro-inflammatory cytokines;
Shikonin protects H9C2 cardiomyocytes against hypoxia/reoxygenation injury through activation of PI3K/Akt signaling pathway
Keywords: تماشای; Shikonin; H9C2 cells; Hypoxia/reoxygenation injury; Viability; Mitochondria-dependent apoptosis; PI3K/Akt signaling;
Shikonin upregulates the expression of drug-metabolizing enzymes and drug transporters in primary rat hepatocytes
Keywords: تماشای; AhR; aryl hydrocarbon receptor; AP1; activating protein 1; ARE; antioxidant-response element; CAR; constitutive androstane receptor; CYP; cytochrome P450; DREs; dioxin-responsive elements; EMSA; electromobility gel shift assay; FBS; fetal bovine serum; GS
The evaluation of potent antitumor activities of shikonin coumarin-carboxylic acid, PMMB232 through HIF-1α-mediated apoptosis
Keywords: تماشای; HIF-1α; hypoxia-inducible factor alpha 1; DMAP; 4 dimethyamino- pyridine; DCC; N, N' dicyclohexylcarbodiimide; DMEM; Dulbecco's modified Eagle's medium; MTT; 3-(4 5-dimethyl-2-thiazolyl)-2 5-diphenyl-2-H-tetrazolium bromide; IC50; Half of maximal i
Design and characterization of α-lipoic acyl shikonin ester twin drugs as tubulin and PDK1 dual inhibitors
Keywords: تماشای; Cancer; Shikonin; Twin drug; Pyruvate dehydrogenase kinase; Tubulin; CADD; computer assistant drug design; NOS; nitric oxide synthase; PKM2; pyruvate kinase isozymes M2; GLUT1; Glucose transporter 1; LA; alpha-lipoic acid; PDH; pyruvate dehydrogenase; PDC
Shikonin enhances sensitization of gefitinib against wild-type EGFR non-small cell lung cancer via inhibition PKM2/stat3/cyclinD1 signal pathway
Keywords: تماشای; Shikonin; Gefitinib; PKM2; STAT3; CyclinD1;
Lactoferrin functionalized PEG-PLGA nanoparticles of shikonin for brain targeting therapy of glioma
Keywords: تماشای; Shikonin; Glioma; Nanoparticles;
SIRT2 mediated antitumor effects of shikonin on metastatic colorectal cancer
Keywords: تماشای; SIRT2; Shikonin; Colorectal cancer; Metastasis; Phospho-extracellular signal-regulated kinases (p-ERK);
Regulation of miRNAs by herbal medicine: An emerging field in cancer therapies
Keywords: تماشای; Micro RNA; Herbal medicine; Shikonin; Sinomenium acutum; Curcumin; Olea europaea; Ginseng; Coptidis rhizoma;
Antiviral activity of a synthesized shikonin ester against influenza A (H1N1) virus and insights into its mechanism
Keywords: تماشای; CC50; half-maximal cytotoxic concentration; CPE; cytopathic effect; DMEM; Dulbecco's modified Eagle's medium; DMSO; dimethyl sulfoxide; FBS; fetal bovine serum; HA; hemagglutinin; MDCK; Madin-Darby canine kidney cells; MOI; multiplicity of infection;
Assessment of the inhibition risk of shikonin on cytochrome P450 via cocktail inhibition assay
Keywords: تماشای; Cytochrome P450; Drug-drug interactions; Food-drug interactions; Shikonin; Cocktail approach;
Selected secondary metabolites in Echium vulgare L. populations from nonmetalliferous and metalliferous areas
Keywords: تماشای; Echium vulgare; Boraginaceae; Metallicolous population; Heavy metals; Allantoin; Shikonin; Phenolic compounds; Flavonoids; Antioxidant capacity;
Original ArticleRIP1 and RIP3 contribute to shikonin-induced DNA double-strand breaks in glioma cells via increase of intracellular reactive oxygen species
Keywords: تماشای; Glioma cell; RIP1 and RIP3; DNA double strand breaks; ROS; Shikonin;
Identification of new shikonin derivatives as STAT3 inhibitors
Keywords: تماشای; Shikonin (PubChem CID: 479503); Plumbagin (PubChem CID: 10205); STA-21 (PubChem CID: 363709); Napabucasin (PubChem CID: 10331844); STAT3 inhibitors; Shikonin; Structural modifications; Anti-neoplastic; Breast cancer;
Sensitive and selective voltammetric determination of antiËcancer agent shikonin on sepiolite clay/TiO2 nanoparticle/MWCNTs composite carbon paste sensor and investigation of its electroËoxidation mechanism
Keywords: تماشای; Shikonin; Composite electrode; Sepiolite clay; TiO2 nanoparticles; Multiwalled carbon nanotubes; Carbon paste electrode;
Enhancement of cisplatin-induced colon cancer cells apoptosis by shikonin, a natural inducer of ROS in vitro and in vivo
Keywords: تماشای; Cisplatin; ROS; Shikonin; Mitochondrial dysfunction; Colon cancer;
Biological efficacy and radical scavenging potential of shikonin in Arnebia benthamii (Wall ex. G Don) Johnston
Keywords: تماشای; DPPH; 1,1-diphenyl-2-picryl-hydrazyl; EA; ethyl acetate; NWH; North Western Himalaya; NBT; nitro blue tetrazolium chloride; ROS; reactive oxygen species; SOD; superoxide dismutase; Antioxidant; HPLC; Kahzaban; Shikonin; Dye; DNA damage;
Shikonin causes apoptosis by up-regulating p73 and down-regulating ICBP90 in human cancer cells
Keywords: تماشای; Shikonin; Tumor suppressor gene; Apoptosis; p73; ICBP90; p16INK4A;
Cytotoxicity of natural products and derivatives toward MCF-7 cell monolayers and cancer stem-like mammospheres
Keywords: تماشای; Drug resistance; Mammospheres; Cancer stem-like cells; Cajanin stilbene acid (CSA); Shikonin; Artesunate
Shikonin inhibits oxidized LDL-induced monocyte adhesion by suppressing NFκB activation via up-regulation of PI3K/Akt/Nrf2-dependent antioxidation in EA.hy926 endothelial cells
Keywords: تماشای; Adhesion molecules; Antioxidant defense; Nuclear factor-kappaB (NFκB); Nuclear factor erythroid 2-related factor 2 (Nrf2); Oxidized LDL; Shikonin;
Shikonin protects against obesity through the modulation of adipogenesis, lipogenesis, and β-oxidation in vivo
Keywords: تماشای; Shikonin; Anti-obesity; Mice; Lipogenesis; Fatty acid oxidation; AdipogenesisACCα, acetyl-CoA carboxylase α; ACOX1, peroxisomal acyl-coenzyme A oxidase 1; ACSL, long-chain acyl-CoA synthetase; ALT, alanine aminotransferase; aP2, fatty acid binding protein
Fabrication of nanostructured PEDOT clusters using β-cyclodextrin as substrate and applied for simultaneous determination of hyperoside and shikonin
Keywords: تماشای; Nanostructured PEDOT/β-CD; Shikonin; Hyperoside; Simultaneous determination;
Shikonin inhibits the lipopolysaccharide-induced release of HMGB1 in RAW264.7 cells via IFN and NF-κB signaling pathways
Keywords: تماشای; Shikonin; Lipopolysaccharides; Macrophages; High mobility group box 1; IFN-β; NF-κB
Shikonin suppresses IL-17-induced VEGF expression via blockage of JAK2/STAT3 pathway
Keywords: تماشای; Shikonin; IL-17; STAT3; VEGF
Shikonin induces cell cycle arrest in human gastric cancer (AGS) by early growth response 1 (Egr1)-mediated p21 gene expression
Keywords: تماشای; CDK; cyclin dependent kinase; ChIP; chromatin immunoprecitiation; CKI; cyclin-dependent kinase; Egr1; early growth response 1; siRNA; small interfering RNA; Anti-proliferation; Cell cycle arrest; Egr1; p21; Shikonin;
Shikonin inhibits prostate cancer cells metastasis by reducing matrix metalloproteinase-2/-9 expression via AKT/mTOR and ROS/ERK1/2 pathways
Keywords: تماشای; Shikonin; Human prostate cancer; Migration; Invasion; Matrix metalloproteinase;
Shikonin targets cytosolic thioredoxin reductase to induce ROS-mediated apoptosis in human promyelocytic leukemia HL-60 cells
Keywords: تماشای; Thioredoxin reductase; Shikonin; Reactive oxygen species; Redox; Apoptosis; Free radicals;
Shikonin suppresses tumor growth and synergizes with gemcitabine in a pancreatic cancer xenograft model: Involvement of NF-κB signaling pathway
Keywords: تماشای; Shikonin; Gemcitabine; Pancreatic Cancer; NF-κB;
Shikonin attenuates lung cancer cell adhesion to extracellular matrix and metastasis by inhibiting integrin β1 expression and the ERK1/2 signaling pathway
Keywords: تماشای; Shikonin; Lung cancer; Cell adhesion; Metastasis; Integrin β1; ERK1/2;
Shikonin promotes intestinal wound healing in vitro via induction of TGF-β release in IEC-18 cells
Keywords: تماشای; IEC-18 cells; Shikonin; TGF-β; Ulcerative colitis; Wound healingBSA, bovine serum albumin; CD, Crohn’s disease; DMEM, Dulbecco’s Modified Eagle’s Medium; DSS, dextran sulfate sodium; IBD, inflammatory bowel disease; MTT, 3-[4,5-dimethylthiazol-2-yl]-2,5-d
Molecularly imprinted polymers for the isolation of bioactive naphthoquinones from plant extracts
Keywords: تماشای; Shikonin; Alkannin; Naphthazarin; Plant extracts; Molecularly Imprinted Solid Phase Extraction (MI-SPE); Wound healing agents
Shikonin attenuates lipopolysaccharide-induced acute lung injury in mice
Keywords: تماشای; Shikonin; Lipopolysaccharide; Acute lung injury; Cyclooxygenase 2; Inducible nitric oxide synthase; Nuclear factor κB
Shikonin, a natural product from the root of Lithospermum erythrorhizon, is a cytotoxic DNA-binding agent
Keywords: تماشای; Shikonin; Ewing sarcoma; Cytotoxic chemotherapy; Natural product; Transcription; High throughput screen
A novel and efficient total synthesis of shikonin
Keywords: تماشای; Natural product; Shikonin; Total synthesis; Asymmetric hydrogenation;
Synthesis and human telomeric G-quadruplex DNA-binding activity of glucosaminosides of shikonin/alkannin
Keywords: تماشای; Shikonin; Alkannin; Telomeric; G-quadruplex; Glycosylation
Preparation of shikonin by hydrolyzing ester derivatives using basic anion ion exchange resin as solid catalyst
Keywords: تماشای; Hydrolysis preparation; Shikonin; Anion exchange resin; Base solid catalyst; Bi-functional catalyst
Selective and slow-binding inhibition of shikonin derivatives isolated from Lithospermum erythrorhizon on glycosyl hydrolase 33 and 34 sialidases
Keywords: تماشای; Glycosyl hydrolase; Sialidase; Shikonin; Shikonofuran; Lithospermum erythrorhizon;
Shikonin extracted from medicinal Chinese herbs exerts anti-inflammatory effect via proteasome inhibition
Keywords: تماشای; Shikonin; Proteasome inhibitor; Macrophage; Inflammation
Determination of the active constituents in Arnebia euchroma (Royle) Johnst. by ionic liquid-based ultrasonic-assisted extraction high-performance liquid chromatography
Keywords: تماشای; Arnebia euchroma (Royle) Johnst.; Shikonin; β,β′-Dimethylacrylshikonin; Ionic liquid-based ultrasonic-assisted extraction(IL-based UAE); High-performance liquid chromatography (HPLC)