Effects of diphyllin as a novel V-ATPase inhibitor on gastric adenocarcinoma
Keywords: سیگنالینگ; Vacuolar-ATPases; Diphyllin; Gastric cancer; Signaling
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Beta-arrestins as regulators of signal termination and transduction: How do they determine what to scaffold?
Keywords: سیگنالینگ; Arrestins; GPCR; Signaling; Chemotaxis; MAPK; PI3K; PDE4; Ubiquitin;
Fusarium infection in maize: Volatile induction of infected and neighboring uninfected plants has the potential to attract a pest cereal leaf beetle, Oulema melanopus
Keywords: سیگنالینگ; Infestation; Maize; Secondary metabolism; Signaling; Volatiles
Regulation of GPCR signal networks via membrane trafficking
Keywords: سیگنالینگ; GPCR; Trafficking; Signaling; Endocytosis; Recycling; Degradation;
Enhanced airway smooth muscle cell thromboxane receptor signaling via activation of JNK MAPK and extracellular calcium influx
Keywords: سیگنالینگ; TP receptor; Signaling; JNK MAPK; Calcium influx; Airway hyperresponsiveness
The Notch signaling pathway: Molecular basis of cell context dependency
Keywords: سیگنالینگ; Notch receptor; Signaling; Stem cells; Chromatin
Heteromerization of human cytomegalovirus encoded chemokine receptors
Keywords: سیگنالینگ; Human cytomegalovirus; Chemokine receptors; Signaling; Post-endocytic sorting; Heteromerization; G-protein coupled receptor;
Distinct PGE2-responder and non-responder phenotypes in human mast cell populations: “All or nothing” enhancement of antigen-dependent mediator release
Keywords: سیگنالینگ; Mast cells; PGE2; Degranulation; Cytokine release; Signaling;
Electromagnetic fields as first messenger in biological signaling: Application to calmodulin-dependent signaling in tissue repair
Keywords: سیگنالینگ; EMF Mechanism; Signaling; Electrochemical model; Calmodulin; Nitric oxide
Extending life span by increasing oxidative stress
Keywords: سیگنالینگ; Reactive oxygen species; Aging; Anti-aging; Life span; Signaling; Nutrition; Mitohormesis; Free radicals;
Calcium-mediated mechanisms of cystic expansion
Keywords: سیگنالینگ; Primary cilia; Mechanosensor; Signaling; Shear stress
Original ResearchBasic and Translational-Alimentary TractIntestinal Dendritic Cells Specialize to Activate Transforming Growth Factor-β and Induce Foxp3+ Regulatory T Cells via Integrin αvβ8
Keywords: سیگنالینگ; Immune Response; T-Cell Regulation; Signaling; Inflammatory Response; Self Tolerance; DC; dendritic cell; LAP; latency-associated peptide; mIgG; mouse immunoglobulin G; mLN; mesenteric lymph node; qPCR; quantitative polymerase chain reaction; RA; retinoic
Original ResearchBasic and Translational-Alimentary TractLong-term Expansion of Epithelial Organoids From Human Colon, Adenoma, Adenocarcinoma, and Barrett's Epithelium
Keywords: سیگنالینگ; Ex Vivo Culture Technology; Neoplasia; Signaling; Dysplasia; Hayflick Model; DAPI; 4â²,6-diamidino-2-phenylindole; DBZ; dibenzazepine; EGF; epidermal growth factor; ENR; murine epidermal growth factor, murine noggin, human R-spondin-1; g; gastrin; GFP; g
Deletion of Rb Accelerates Pancreatic Carcinogenesis by Oncogenic Kras and Impairs Senescence in Premalignant Lesions
Keywords: سیگنالینگ; Proliferation; Transformation; Signaling; ChemokineADM, acinar-to-ductal metaplasia; CK19, cytokeratin 19; IL, interleukin; MCN, mucinous cystic neoplasia; MCP1, monocyte chemotactic protein-1; MDM2, murine double minute-2; OIS, oncogene-induced senescenc
A search for factors specifying tonotopy implicates DNER in hair-cell development in the chick's cochlea
Keywords: سیگنالینگ; Auditory system; Hair bundle; Planar cell polarity; Signaling
Molecular analysis of nutritional and hormonal regulation of female reproduction in the red flour beetle, Tribolium castaneum
Keywords: سیگنالینگ; RNAi; Vitellogenesis; Insulin; TOR; Signaling; Ovarian maturation; Starvation; Tribolium; Ecdysone; JH
Toll-like Receptor 4 Variant D299G Induces Features of Neoplastic Progression in Caco-2 Intestinal Cells and Is Associated With Advanced Human Colon Cancer
Keywords: سیگنالینگ; Intestine; Signaling; EpitheliumCOX, cyclooxygenase; EMT, epithelial-mesenchymal transition; IEC, intestinal epithelial cell; RT-PCR, reverse-transcriptase polymerase chain reaction; TLR, Toll-like receptor; UICC, International Union Against Cancer; WT, w
β-Catenin and p120 Mediate PPARδ-Dependent Proliferation Induced by Helicobacter pylori in Human and Rodent Epithelia
Keywords: سیگنالینگ; Stomach Cancer; Mongolian Gerbils; Signaling; BacteriaAPC, adenomatous polyposis coli; GSK, glycogen synthase kinase; mmp, matrix metalloproteinase; p120, p120-catenin; PI3K, phosphatidylinositol 3-phosphate kinase; PPAR, peroxisome proliferator-activated
Tapping the brake on cardiac growth-endogenous repressors of hypertrophic signaling-
Keywords: سیگنالینگ; Cardiac hypertrophy; Signaling; Transcriptional regulation; Heart failure; Therapeutic interventions;
Syndecan contributes to heart cell specification and lumen formation during Drosophila cardiogenesis
Keywords: سیگنالینگ; Dorsal vessel; Heart; Morphogenesis; Signaling; Slit; Lumen
PKCθ activation in pancreatic acinar cells by gastrointestinal hormones/neurotransmitters and growth factors is needed for stimulation of numerous important cellular signaling cascades
Keywords: سیگنالینگ; CCK; COOH-terminal octapeptide of cholecystokinin; TPA; 12-O-tetradecanoylphorbol-13-acetate; GI; gastrointestinal; CCK-JMV; CCK-JMV-180; IP; immunoprecipitation; Co-IP; co-immunoprecipitation; PKD; protein kinase D; GPCR; G protein-coupled receptor; PYK2
Experimental and computational approaches for the study of calmodulin interactions
Keywords: سیگنالینگ; Arabidopsis; Calcium; Ca2+ sensors; Calmodulin; CaM-binding proteins; Signaling; Bioinformatics; Interaction prediction; Protein-protein interactions; Proteome; Protein chip;
Enteric Neuronal Density Contributes to the Severity of Intestinal Inflammation
Keywords: سیگنالینگ; IBD; Signaling; Crohn's Disease; Colitis; ANOVA; analysis of variance; DNFB; 2,4-dinitro-1-fluorobenzene; DSS; dextran sulfate sodium; DTH; delayed-type hypersensitivity; ELISA; enzyme-linked immunosorbent assay; ENS; enteric nervous system; GAPDH; glycer
Hepatocyte growth factor-induced c-Src-phosphatidylinositol 3-kinase-AKT-mammalian target of rapamycin pathway inhibits dendritic cell activation by blocking IκB kinase activity
Keywords: سیگنالینگ; c-MET; Dendritic cell; Hepatocyte growth factor; NF-κB; Signaling
Competition and the signaling role of prices
Keywords: سیگنالینگ; D4; D8; L15; Market for lemons; Adverse selection; Price dispersion; Price-setting; Signaling; Competition;
Remittances as a social status signaling device
Keywords: سیگنالینگ; Migration; Remittances; Social status; Perfect Bayesian equilibrium; Signaling
Active Mutants of the TCR-Mediated p38α Alternative Activation Site Show Changes in the Phosphorylation Lip and DEF Site Formation
Keywords: سیگنالینگ; MAP kinase; p38α; T-cells; signaling; alternative activationMAPK, mitogen-activated protein kinase; ERK, extracellular signal-regulated kinase; MKK, MAPK kinase; MKI, MAPK insert; ATF, activating transcription factor; β-OG, n-octyl-β-d-glucopyranoside; ES
When should a firm expand its business?: The signaling implications of business expansion
Keywords: سیگنالینگ; L12; D82; Business expansion; Signaling; Entry deterrence; Failure rates;
Loss of Glucagon-Like Peptide-2-Induced Proliferation Following Intestinal Epithelial Insulin-Like Growth Factor-1-Receptor Deletion
Keywords: سیگنالینگ; Enteroendocrine L Cell; Growth; Signaling; Mouse Model; cWNT; canonical Wingless chromosomal integration site of mouse mammary tumor virus on mouse chromosome 15; ErbB; epidermal growth factor R; GLP-2R; glucagon-like peptide-2 receptor; IE-igf1rKO; delet
Annexin A2 Mediates Up-regulation of NF-κB, β-catenin, and Stem Cell in Response to Progastrin in Mice and HEK-293 Cells
Keywords: سیگنالینگ; CD44; DCAMKL+1; Colorectal Cancer; Signaling; AnxA2; annexin A2; ANXA2+/+ mice; wild-type C57Bl/J6 mice; ANXA2â/â mice; C57Bl/J6 mice knocked down for the expression of annexin A2; CCK1R and CCK2R; cholecystokinin type 1 and type 2 receptors, respecti
Do dividend changes signal future earnings?
Keywords: سیگنالینگ; C72; D82; G35Dividend policy; Non-monotone contracts; Signaling; Single-crossing property
Diverse functions for the semaphorin receptor PlexinD1 in development and disease
Keywords: سیگنالینگ; Semaphorin; Sema; Plexin; Plxn; PlexinD1; PlxnD1; Signaling; Review; Blood vessel; Angiogenesis; Nervous system; Axon guidance; Tumor; Cancer; Immune;
Early Requirement of Rac1 in a Mouse Model of Pancreatic Cancer
Keywords: سیگنالینگ; Genetically Engineered Mice; Ductal Cell; Cytoskeleton; Signaling; ADM; acinar-ductal metaplasia; BrdU; bromodeoxyuridine; CK19; cytokeratin 19; CytD; cytochalasin D; EGFR; epidermal growth factor receptor; LatA; latrunculin A; PanIN; pancreatic intraepit
Cellular magnesium homeostasis
Keywords: سیگنالینگ; Mg2+; Mg2+ transport; Channel; Exchanger; Cellular organelles; Signaling
Kindler Syndrome Pathogenesis and Fermitin Family Homologue 1 (Kindlin-1) Function
Keywords: سیگنالینگ; Genodermatosis; Keratinocyte adhesion; Keratinocyte proliferation; Signaling; Focal contact; Fermitin family homologue 1 (FFH1); Ultrastructure;
Signal jamming in a sequential auction
Keywords: سیگنالینگ; D02; D08; D43; D44; Auctions; Signaling; Price competition;
Beyond the signaling effect role of amyloid-β42 on the processing of APP, and its clinical implications
Keywords: سیگنالینگ; Aging; Alzheimer's disease; Amyloid beta peptide; Clinical trial; Dementia; Drug discovery; Gene regulation; Molecular pharmacology; Signaling; Transcription factor; Treatment
Cross-talk between transforming growth factor-β and Wingless/Int pathways in lung development and disease
Keywords: سیگنالینگ; TGf-beta; Wnt; Signaling; Lung disease; Lung morphogenesis
Sucrose: Metabolite and signaling molecule
Keywords: سیگنالینگ; Sucrose; Signaling; Metabolism; Arabidopsis; Carbon transport; Gene expression;
IFNγ mediates DUOX2 expression via a STAT-independent signaling pathway
Keywords: سیگنالینگ; Dual oxidase; DUOX; Gamma interferon; JAK; STAT; Signaling
A Role for S6 Kinase and Serotonin in Postmating Dietary Switch and Balance of Nutrients in D. melanogaster
Keywords: سیگنالینگ; SIGNALING; DEVBIO
Overlapping and distinct functions of two Trichoderma virens MAP kinases in cell-wall integrity, antagonistic properties and repression of conidiation
Keywords: سیگنالینگ; MAP kinase; MAPK; Fungal; Trichoderma; Biocontrol; Cell-wall integrity; Signaling
Tenofovir treatment of primary osteoblasts alters gene expression profiles: Implications for bone mineral density loss
Keywords: سیگنالینگ; Bone; Nucleotide; Metabolism; HIV; Osteoclast; Cell cycle; Signaling;
Endothelial cells are activated during hypoxia via endoglin/ALK-1/SMAD1/5 signaling in vivo and in vitro
Keywords: سیگنالینگ; Heart; Infarction; Hypoxia; Endoglin; Signaling
Transdominant regulation of integrin function: Mechanisms of crosstalk
Keywords: سیگنالینگ; Matrix adhesion; Receptors; Cytoskeleton; Signaling; Adaptor proteins; Phosphorylation
Use of plasmon waveguide resonance (PWR) spectroscopy for examining binding, signaling and lipid domain partitioning of membrane proteins
Keywords: سیگنالینگ; PWR spectroscopy; G-Protein coupled receptors; Ligand binding; Signaling; Lipid domains
MAPK Substrate Competition Integrates Patterning Signals in the Drosophila Embryo
Keywords: سیگنالینگ; SIGNALING
Coagulation Factor Xa inhibits cancer cell migration via LIMK1-mediated cofilin inactivation
Keywords: سیگنالینگ; Coagulation factor Xa; Cancer cell; Cell migration; Protease activated receptor; Signaling
A role of Histidine151 in the lamprey gonadotropin-releasing hormone receptor-1 (lGnRHR-1): Functional insight of diverse amino acid residues in the position of Tyr of the DRY motif in GnRHR from an ancestral type II receptor
Keywords: سیگنالینگ; GnRH receptor; DRY motif; Receptor expression; Signaling; Site-directed mutagenesis; Lamprey;
Fine-tuning the brain: MicroRNAs
Keywords: سیگنالینگ; MicroRNA; Glucocorticoids; Neurogenesis; Development; Signaling; Translation; Non-coding RNA; Plasticity; Feedback loop