دانلود مقالات ISI درباره Sirtuin 1 + ترجمه فارسی

Caloric restriction, resveratrol and melatonin: Role of SIRT1 and implications for aging and related-diseases

Keywords: Aβ; amyloid β protein; AMPK; adenosine monophosphate activated protein kinase; CGNs; cerebellar granule neurons; ETC; electron transport chain; H2O2; hydrogen peroxide; HO-1; heme oxygenase-1; LXR; liver X receptor; MAPK; mitogen-activated protein kinas

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

Pathological changes in hippocampal neuronal circuits underlie age-associated neurodegeneration and memory loss: Positive clue toward SAD

Keywords: AD; Alzheimer's disease; CV; Cresyl Violet; DG; dentate gyrus; EC; entorhinal cortex; FC; frontal cortex; ML; molecular layer; NBF; neutral buffered formalin; PaS; parasubiculum; PFC; prefrontal cortex; PP; perforant path; PrS; presubiculum; RAM; radial

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2015 سفارش ترجمه

Peripheral leukocyte expression of the potential biomarker proteins Bdnf, Sirt1, and Psen1 is not regulated by promoter methylation in Alzheimer's disease patients

Keywords: Alzheimer disease; Biomarkers; Brain derived neurotrophic factor; DNA methylation; Presenilin 1; Sirtuin 1; AD; Alzheimer's disease; APP; amyloid precursor protein; CpG; cytosine-guanine; MMSE; Mini-Mental State Examination; MCI; mild cognitive impairme

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2015 سفارش ترجمه

Sirtuin 1 attenuates oxidative stress via upregulation of superoxide dismutase 2 and catalase in astrocytes

Keywords: Sirtuin 1; Astrocyte; Superoxide dismutase 2; Catalase; Forkhead box protein O4; Reactive oxygen species

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Mussel oligopeptides protect human fibroblasts from hydrogen peroxide (H2O2)-induced premature senescence

Keywords: CK; control experiment; DMSO; dimethylsulfoxide; MTT; 3-(4,5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide; NAMPT; nicotinamide phosphoribosyltransferase; Prx1; peroxiredoxin 1; PSC; premature senescence control; SA-β-gal; senescence-associated

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

2-(2-Bromophenyl)-formononetin and 2-heptyl-formononetin are PPARγ partial agonists and reduce lipid accumulation in 3T3-L1 adipocytes

Keywords: 2BrPhF; 2-(2-bromophenyl)-formononetin; C7F; 2-heptyl-formononetin; AICAR; 5-amino-1-β-d-ribofuranosyl-imidazole-4-carboxamide; AMPK; AMP-activated protein kinase; PPAR; peroxisome proliferator-activated receptor; Sirt1; sirtuin 1; Adipocytes; Isoflavone

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Rosuvastatina mejora la sensibilidad a la insulina en ratas con sobrepeso inducido por dieta grasa. Papel de sirtuina 1 en el tejido adiposo

Keywords: Estatinas; Resistencia a la insulina; Sobrepeso; Tejido adiposo; Sirtuina 1Statin; Insulin resistance; Overweight; Adipose tissue; Sirtuin 1

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Sesamin ameliorates doxorubicin-induced cardiotoxicity: Involvement of Sirt1 and Mn-SOD pathway

Keywords: Ses; sesamin; DOX; doxorubicin; Mn-SOD; Manganese SOD; Sirt1; Sirtuin 1; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; ROS; reactive oxygen species; MDA; malondialdehyde; Doxorubicin; Sesamin; Mn-SOD; Sirt1; Cardiotoxicity;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Gene expression profiling of SIRT1, FoxO1, and PPARγ in backfat tissues and subcutaneous adipocytes of Lilu bulls

Keywords: Backfat tissue; Subcutaneous adipocytes; Sirtuin 1; Forkhead box O1; Peroxisome proliferator-activated receptor-γ;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Identification, stability and expression of Sirt1 antisense long non-coding RNA

Keywords: lncRNA; long noncoding RNA; Sirt1; Sirtuin 1; NATs; natural antisense transcripts; RBPs; RNA-binding proteins; miRNAs; microRNA; HuR; human antigen R; AS; antisense transcripts; UCH1; Ubiquitin Carboxyl-Terminal Esterase L1; Ptprj; Protein Tyrosine Phosph

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Arsenic exposure disrupts epigenetic regulation of SIRT1 in human keratinocytes

Keywords: As(III), inorganic arsenite; NMSC, non-melanoma skin cancer; H4K16, histone 4 lysine 16; NHEK, normal human epidermal keratinocyte; MNase, micrococcal nuclease; DNMT1, DNA methyltransferase 1; PRG, polycomb repressive group complexArsenic; Sirtuin 1; MiR-

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Liquid fructose downregulates Sirt1 expression and activity and impairs the oxidation of fatty acids in rat and human liver cells

Keywords: ACO; acyl-CoA oxydase; AMPK; AMP-activated protein kinase; APRT; adenosyl phosphoribosyl transferase); ACC; acetyl-CoA carboxylase); ChREBP; carbohydrate response element binding protein; CYP4A1; cytochrome P450 4A1; FAS; fatty acid synthase; Foxa2; forkh

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

The role of p38 signaling and poly(ADP-ribosyl)ation-induced metabolic collapse in the osteogenic differentiation-coupled cell death pathway

Keywords: AIF; apoptosis inducing factor; AP-1; activating protein-1; AP-2; activating protein 2; BMP2; bone morphogenetic protein 2; cMSC; chorion-derived mesenchymal stem cells; CTRL; control cells; DIFF; differentiating cells; ECAR; extracellular acidification r

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Intestine-Specific Deletion of SIRT1 in Mice Impairs DCoH2-HNF-1α-FXR Signaling and Alters Systemic Bile Acid Homeostasis

Keywords: Ileal Bile Acid Absorption; Bile Acid Synthesis; Liver Damage; Cholestasis; CA; cholic acid; DCoH2; dimerization cofactor of hepatocyte nuclear factor 1α 2; FGF15; fibroblast growth factor 15; FXR; farnesoid X receptor; HA; hemagglutinin; HNF-1α; hepato

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Alpha-lipoic acid improves high-fat diet-induced hepatic steatosis by modulating the transcription factors SREBP-1, FoxO1 and Nrf2 via the SIRT1/LKB1/AMPK pathway

Keywords: ACC; acetyl-CoA carboxylase; ALA; alpha-lipoic acid; ALT; alanine aminotransferase; AICAR; 5-aminoimidazole-4-carboxamide riboside; AMPK; AMP-activated protein kinase; AST; aspartate aminostransferase; ATGL; adipose triacylglycerol lipase; CaMKK; Ca2+/cal

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Aspirin attenuates vinorelbine-induced endothelial inflammation via modulating SIRT1/AMPK axis

Keywords: VNR; vinorelbine; SIRT1; sirtuin 1; AMPK; AMP-activated protein kinase; PKC; protein kinase C; LKB1; protein liver kinase B1; TAK1; TGF-β-activated kinase-1; TAB1; TAK-binding protein-1; ROS; reactive oxygen species; DCF-AM; 2′,7′-dichlorofluorescein

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

SIRT1 and NAD as regulators of ageing

Keywords: SIRT 1; Sirtuin 1; SCN; hypothalamic suprachiasmatic nucleus; PBEF; nicotinamide phosphoribosyltransferase gene; CLOCK; circadian locomotor output cycles kaput gene; CLOCK; circadian locomotor output cycles kaput gene; PER2; period circadian protein homol

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2014 سفارش ترجمه

Histone deacetylase inhibitor (HDACI) mechanisms of action: Emerging insights

Keywords: HDAC inhibitor; DNA damage response; DNA repair; Cell cycle checkpoints; Apoptosis; Rational combinations; ALL; acute lymphoblastic leukemia; AML; acute myeloid leukemia; APAF-1; apoptotic protease activating factor 1; ASK1; apoptosis signal-regulating ki

دانلود رایگان متن کامل مقاله ISI 78 صفحه سال انتشار : 2014 سفارش ترجمه

Cardiovascular pharmacologySirtuin 1 is upregulated in young obese Zucker rat cerebral arteries

Keywords: Cerebrovasculature; Endothelium; Metabolic syndrome; Nitric oxide; Oxidative stress; Sirtuin 1;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Research ArticlemiR-34a/SIRT1/p53 is suppressed by ursodeoxycholic acid in the rat liver and activated by disease severity in human non-alcoholic fatty liver disease

Keywords: Apoptosis; miRNAs; NAFLD; p53; SIRT1; UDCA; NAFLD; non-alcoholic fatty liver disease; NASH; non-alcoholic steatohepatitis; miRNA or miR; microRNA; SIRT1; Sirtuin 1; UDCA; ursodeoxycholic acid; CA; cholic acid; FFAs; free fatty acids; JNK; c-Jun N-terminal

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Breed difference of porcine Sirtuin 1, adipose triglyceride lipase (ATGL) and hormone sensitive lipase (HSL)

Keywords: Adipose triglyceride lipase; Fat deposition; Hormone sensitive lipase; Insulin; Pig; Sirtuin 1;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Down-regulation of NAMPT expression by miR-182 is involved in Tat-induced HIV-1 long terminal repeat (LTR) transactivation

Keywords: HIV-1; human immunodeficiency virus type 1; LTR; long terminal repeats; PTM; post-translational modification; SIRT1; sirtuin 1; NAD+; nicotinamide adenine dinucleotide; NAMPT; nicotinamide phosphoribosyltransferase; DMEM; Dulbecco's modified Eagle's mediu

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Regulation of cardiac and renal ischemia-reperfusion injury by microRNAs

Keywords: MicroRNAs; Ischemia-reperfusion injury; Kidney; Heart; Free radicals; CaMKII; calmodulin kinase II; DRP1; dynamin-related protein-1; EPC; endothelial progenitor cell; FGFR2; fibroblast growth factor receptor 2; Hsp20; heat shock protein 20; HIF-1α; hyp

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Accelerated recovery of renal mitochondrial and tubule homeostasis with SIRT1/PGC-1α activation following ischemia-reperfusion injury

Keywords: SIRT1; sirtuin 1; PGC-1α; peroxisome proliferator activated receptor γ coactivator-1α; ATPβ; ATP synthase subunit β; COX I; cytochrome c oxidase subunit I; NDUFB8; NADH dehydrogenase (ubiquinone) 1 beta subcomplex 8; Drp1; dynamin related protein 1;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Pharmacological activation of AMPK suppresses inflammatory response evoked by IL-6 signalling in mouse liver and in human hepatocytes

Keywords: AICAR; 5-amino-4-imidazole-carboxamideriboside; ACC; acetyl-CoA carboxylase; ALT; alanine aminotransferase; AMPK; AMP-activated protein kinase; CRP; C-reactive protein; HP; haptoglobin; IKK; IkappaB kinase; IL-6; Interleukin-6; IL6Rα; IL-6 receptor subun

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Targeted acetylation of NF-kappaB/RelA and histones by epigenetic drugs reduces post-ischemic brain injury in mice with an extended therapeutic window

Keywords: CBP; p300/CREB-binding protein; CSF; cerebrospinal fluid; DIV; days in vitro; LDH; lactate dehydrogenase; ip; intraperitoneal; K310; lysine 310; MCAO; middle cerebral artery occlusion; NF-κB; nuclear factor kappa B; OGD; oxygen glucose deprivation; SIRT1

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Sirt1-deficient mice exhibit an altered cartilage phenotype

Keywords: Sirtuin 1; Cartilage; Osteoarthritis; Animal models

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Herbal medicines for the prevention of alcoholic liver disease: A review

Keywords: ACC; acetyl-CoA carboxylase; ACLY; ATP-citrate lyase; ALD; alcoholic liver disease; ALP; alkaline phosphatase; ALT; alanine aminotransferase; AMPK; AMP-activated protein kinase; AST; aspartate aminotransferase; AOX; acyl-CoA oxidase; CAT; catalase; COX-2;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Long-term physical exercise induces changes in sirtuin 1 pathway and oxidative parameters in adult rat tissues

Keywords: Sirtuin 1; AMPK; PGC-1α; Mitochondrial biogenesis; Oxidative stress; Treadmill; Liver; Heart; Muscle

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Activation of SIRT1 protects pancreatic β-cells against palmitate-induced dysfunction

Keywords: FFA; free fatty acid; PDX1; pancreatic and duodenal homeobox 1; GSIS; glucose-stimulated insulin secretion; JNK; Jun N-terminal kinase; SIRT1; sirtuin 1; PGC-1; peroxisome proliferator-activated receptor gamma coactivator 1; NeuroD; neurogenic differentia

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Proteases involved in cartilage matrix degradation in osteoarthritis

Keywords: ADAMTS; a disintegrin and metalloproteinase with thrombospondin motifs; APC; activated protein C; CITED2; cAMP-responsive element-binding protein/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 2; ECM; extracellular matrix; ERK;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2012 سفارش ترجمه

Histone modifications as a pathogenic mechanism of colorectal tumorigenesis

Keywords: AP2A1; adaptor related protein complex 2, subunit alpha 1; APAF1; apoptotic protease activating factor 1; APC; adenomatous polyposis coli; BRCA1, 2; breast cancer 1, 2; CARM1; co-activator-associated arginine methyltransferase 1; CBP; cAMP-responsive elem

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2012 سفارش ترجمه

Oxidative stress, insulin signaling, and diabetes

Keywords: AGE; advanced glycated end product; CAP; c-Cbl-associated protein; DAG; diacylglycerol; eNOS; endothelial nitric oxide synthase; ERK; extracellular signal-regulated kinase; ETC; electron transport chain; GH; growth hormone; GLUT4; glucose transporter type

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Neuroprotective role of intermittent fasting in senescence-accelerated mice P8 (SAMP8)

Keywords: Ageing; Neurodegeneration; NFκB; ADAM10; BDNF; Sirtuin 1

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Carboxy-terminal phosphorylation of SIRT1 by protein kinase CK2

Keywords: SIRT1; Sirtuin 1; Phosphorylation

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Acetylation of FoxO1 Activates Bim Expression to Induce Apoptosis in Response to Histone Deacetylase Inhibitor Depsipeptide Treatment

Keywords: CBP; cyclic adenosine monophosphate-responsive element-binding protein-binding protein; FHL2; four-and-a-half LIM-domain protein 2; FoxO1; forkhead box class O1; HDAC inhibitor; histone deacetylase inhibitor; PI3-K; phosphatidylinositol 3-kinase; PKB/Akt;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2009 سفارش ترجمه