دانلود مقالات ISI درباره mutagenesis مواجه با سایت + ترجمه فارسی

Features of a twin-arginine signal peptide required for recognition by a Tat proofreading chaperone

Keywords: mutagenesis مواجه با سایت; Tat, twin-arginine translocation; TMAO, trimethylamine N-oxideBacterial respiration; Bacterial protein targeting; Twin-arginine signal peptide; Tat proofreading chaperone; Protein–protein interaction; Site-directed mutagenesis

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

The crucial amino acid residue related to inactivation of Vibrio vulnificus hemolysin

Keywords: mutagenesis مواجه با سایت; Vibrio vulnificus; Hemolysin; In vitro translation; Site-directed mutagenesis

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

Molecular modeling of the human multidrug resistance protein 1 (MRP1/ABCC1)

Keywords: mutagenesis مواجه با سایت; Multidrug resistance protein; ABC transporter; Organic anion transporter; Homology modeling; MRP1; Sav1866; Site-directed mutagenesis

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

Effects of mutations in the heme domain on the transcriptional activity and DNA-binding activity of NPAS2

Keywords: mutagenesis مواجه با سایت; Heme-sensor protein; PAS domain; DNA binding; Transcription; Circadian rhythm; Site-directed mutagenesis; E-box; Clock genes

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

S-Adenosylhomocysteine hydrolase (AdoHcyase) deficiency: Enzymatic capabilities of human AdoHcyase are highly effected by changes to codon 89 and its surrounding residues

Keywords: mutagenesis مواجه با سایت; Human mutation; Thermosensitivity; Circular dichroism; Functional genomics; Site-directed mutagenesis;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

Role of the invariant Asn345 and Asn435 residues in a leucine aminopeptidase from Bacillus kaustophilus as evaluated by site-directed mutagenesis

Keywords: mutagenesis مواجه با سایت; Bacillus kaustophilus; Leucine aminopeptidase; Computer modeling; Site-directed mutagenesis; Tryptophan emission fluorescence; Circular dichroism

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

Residues Arg114 and Arg337 are critical for the proper function of Escherichia coli γ-glutamyltranspeptidase

Keywords: mutagenesis مواجه با سایت; Escherichia coli; γ-Glutamyltranspeptidase; Site-directed mutagenesis; Autocatalytic processing; Computer modeling

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

Comparative characterization of four laccases from Trametes versicolor concerning phenolic C-C coupling and oxidation of PAHs

Keywords: mutagenesis مواجه با سایت; Laccase; Trametes versicolor; Polycyclic aromatic hydrocarbons; Oxidation; C-C coupling; Site-directed mutagenesis;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

Human pancreatic ribonuclease presents higher endonucleolytic activity than ribonuclease A

Keywords: mutagenesis مواجه با سایت; Human pancreatic ribonuclease; Substrate cleavage preference; Non-catalytic binding subsites; Site-directed mutagenesis;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

Were there any “misassignments” among iron-sulfur clusters N4, N5 and N6b in NADH-quinone oxidoreductase (complex I)?

Keywords: mutagenesis مواجه با سایت; Complex I; Iron-sulfur cluster; EPR; Site-directed mutagenesis; NADH-Q oxidoreductase;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Effects of introducing negative charges into the molecular surface of thermolysin by site-directed mutagenesis on its activity and stability

Keywords: mutagenesis مواجه با سایت; FAGLA; N-[3-(2-furyl)acryloyl]-glycyl-l-leucine amideMetalloproteinase; Molecular surface; Site-directed mutagenesis; Thermal stability; Thermolysin

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Molecular probing of the Saccharomyces cerevisiae sterol 24-C methyltransferase reveals multiple amino acid residues involved with C2-transfer activity

Keywords: mutagenesis مواجه با سایت; SMT; Sterol 24-C methyltransferase; GC-MS; Gas chromatograph-mass spectroscopy; Zymosterol; Fecosterol; Site-directed mutagenesis; Sterol catalysis; Sterol methyltransferase yeast; Saccharomyces cerevisiae; Active site; Erg6p;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Identification of functionally important amino acid residues in the mitochondria targeting sequence of Hepatitis B virus X protein

Keywords: mutagenesis مواجه با سایت; Hepatitis virus; HBx gene; Mitochondria targeting; Site-directed mutagenesis

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Why is it so difficult to construct Qi site mutants in Chlamydomonas reinhardtii?

Keywords: mutagenesis مواجه با سایت; Cytochrome b6fb6f complex; Qi site; Site-directed mutagenesis; Heme; PhotosynthesisComplexe cytochrome b6fb6f; Site Qi; Mutagenèse dirigée; Hème; Photosynthèse

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Studies of the melatonin binding site location onto quinone reductase 2 by directed mutagenesis

Keywords: mutagenesis مواجه با سایت; Melatonin; MT3; Human quinone oxidoreductase 2 (hQR2); Site-directed mutagenesis; Binding; Catalytic activity

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Cinnamyl-3,4-dihydroxy-α-cyanocinnamate and nordihydroguaiaretic acid inhibit human Kv1.5 currents independently of lipoxygenase

Keywords: mutagenesis مواجه با سایت; Kv1.5; IKur; CDC; NDGA; Lipoxygenase; Open channel block; Site-directed mutagenesis

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Kinetic analyses of recombinant isoforms of phosphoenolpyruvate carboxylase from Hydrilla verticillata leaves and the impact of substituting a C4-signature serine

Keywords: mutagenesis مواجه با سایت; Phosphoenolpyruvate carboxylase (PEPC); C3, C4 photosynthesis; Recombinant protein; Site-directed mutagenesis; Kinetic analyses; Aquatic monocot

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

Modeling and experimental analyses reveal a two-domain structure and amino acids important for the activity of aminoglycoside resistance methyltransferase Sgm

Keywords: mutagenesis مواجه با سایت; Antibiotic resistance; Methylation; Modeling; Site-directed mutagenesis

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

Site-directed mutagenesis of the conserved Ala348 and Gly350 residues at the putative active site of Bacillus kaustophilus leucine aminopeptidase

Keywords: mutagenesis مواجه با سایت; Leucine aminopeptidase; Bacillus kaustophilus; Protein modeling; Site-directed mutagenesis; Tryptophan emission fluorescence; Circular dichroism

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

Comparative studies of wild type Escherichia coli 5-enolpyruvylshikimate 3-phosphate synthase with three glyphosate-insensitive mutated forms: Activity, stability and structural characterization

Keywords: mutagenesis مواجه با سایت; EPSP synthase, 5-enolpyruvylshikimate 3-phosphate synthase; CD, circular dichroism5-Enolpyruvylshikimate 3-phosphate (EPSP) synthase; Glyphosate; Stability; Site-directed mutagenesis; Circular dichroism; Fluorescence studies

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

Polar residues in a conserved motif spanning helices 1 and 2 are functionally important in the SulP transporter family

Keywords: mutagenesis مواجه با سایت; SulP family; SLC26 family; Sulfate transporter; Site-directed mutagenesis; Helix packing; Polar amino acids;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

Analysis of CYP2D6 substrate interactions by computational methods

Keywords: mutagenesis مواجه با سایت; Cytochrome P450 (CYP); Automated docking; Homology modelling; Molecular dynamics (MD); Site-directed mutagenesis

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

Exploring the intramolecular phosphorylation sites in human Chk2

Keywords: mutagenesis مواجه با سایت; Chk2; Phosphorylation; Auto-activation; Site-directed mutagenesis; Mass spectrometric analysis;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

Elucidation of active site residues of Arabidopsis thaliana flavonol synthase provides a molecular platform for engineering flavonols

Keywords: mutagenesis مواجه با سایت; Arabidopsis thaliana; Cruciferae; Flavonoids; Quercetin; 2-Oxoglutarate dependent dioxygenase; Flavonol synthase; Site-directed mutagenesis;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

Site-directed mutagenesis of Arginine282 suggests how protons and peptides are co-transported by rabbit PepT1

Keywords: mutagenesis مواجه با سایت; Epithelia; Membrane transport; SLC15a1; Nutrient absorption; Protein structure-function; Site-directed mutagenesis;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

Reversible inactivation of cytochrome P450 by alkaline earth metal ions: Auxiliary metal ion induced conformation change and formation of inactive P420 species in CYP101

Keywords: mutagenesis مواجه با سایت; Cytochrome P450cam; Auxiliary metal ion; Alkaline-earth metal ion; Circular dichroism; Conformational change; Site-directed mutagenesis; Heme; P420

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

The roles of amino acid residues at positions 216 and 219 in the structural stability and metabolic functions of rat cytochrome P450 2D1 and 2D2

Keywords: mutagenesis مواجه با سایت; CYP2D1; CYP2D2; Amino acids at positions 216 and 219; Protein stability; 5-Methoxy-N,N-diisopropyltryptamine; Site-directed mutagenesis

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2008 سفارش ترجمه

Functions of acidic transmembrane residues in human melanocortin-3 receptor binding and activation

Keywords: mutagenesis مواجه با سایت; Melanocortin-3 receptor; Site-directed mutagenesis; Ligand binding; G protein-coupled receptor; Signaling; Structure–function relationship

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2008 سفارش ترجمه

Role of Histidine-152 in cofactor orientation in the PLP-dependent O-acetylserine sulfhydrylase reaction

Keywords: mutagenesis مواجه با سایت; O-Acetylserine sulfhydrylase; Pyridixal 5′-phosphate; Site-directed mutagenesis; 31P NMR; CD spectra; Fluorescence spectra;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2008 سفارش ترجمه

Functional characterization of a Drosophila melanogaster succinic semialdehyde dehydrogenase and a non-specific aldehyde dehydrogenase

Keywords: mutagenesis مواجه با سایت; Succinic semialdehyde dehydrogenase; Aldehyde dehydrogenase; Site-directed mutagenesis; Drosophila melanogaster; GABA catabolism;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2008 سفارش ترجمه

Resistance of herpes simplex virus type 1 to acyclovir: Thymidine kinase gene mutagenesis study

Keywords: mutagenesis مواجه با سایت; Herpes simplex virus; ACV resistance; Thymidine kinase; Site-directed mutagenesis

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2007 سفارش ترجمه

Glu 69 is essential for the high sensitivity of muscle fructose-1,6-bisphosphatase inhibition by calcium ions

Keywords: mutagenesis مواجه با سایت; Calcium; Glyconeogenesis; Muscle fructose-1,6-bisphosphatase; Site-directed mutagenesis;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2007 سفارش ترجمه

Phenylalanine dehydrogenase mutants: Efficient biocatalysts for synthesis of non-natural phenylalanine derivatives

Keywords: mutagenesis مواجه با سایت; Non-natural amino acids; Phenylalanine dehydrogenase; Biocatalysis; Cofactor recycling; Chiral synthesis; Site-directed mutagenesis

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2007 سفارش ترجمه

One-step site-directed mutagenesis of viroid dimeric cDNA

Keywords: mutagenesis مواجه با سایت; Pfu DNA polymerase; Plant biology; QuickChange™; Site-directed mutagenesis; Viroid

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2007 سفارش ترجمه

Enhancing the thermostability of Escherichia colil-asparaginase II by substitution with pro in predicted hydrogen-bonded turn structures

Keywords: mutagenesis مواجه با سایت; l-Asparaginase II; Enzyme activity; Amino acids; Thermostability; Bioinformatics analysis; Site-directed mutagenesis

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2007 سفارش ترجمه

Microbial production of sensory-active miraculin

Keywords: mutagenesis مواجه با سایت; MCL, miraculin; nMCL, native miraculin; rMCL, recombinant miraculinMiraculin; Taste-modifying activity; Sweet protein; Functional expression; Aspergillus oryzae; Site-directed mutagenesis

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2007 سفارش ترجمه

Site-directed mutagenesis of conserved aromatic residues in rat squalene epoxidase

Keywords: mutagenesis مواجه با سایت; Squalene epoxidase; Active site; Site-directed mutagenesis; Substrate specificity; Biosynthesis

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2007 سفارش ترجمه

Changing the substrate specificity of a chitooligosaccharide oxidase from Fusarium graminearum by model-inspired site-directed mutagenesis

Keywords: mutagenesis مواجه با سایت; ChitO, chitooligosaccharide oxidase; MBP, maltose binding protein; HRP, horseradish peroxidase; GlcNac, N-acetyl-d-glucosamineOligosaccharide; Site-directed mutagenesis; N-Acetyl-d-glucosamine; Oxidase

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2007 سفارش ترجمه

Role of homologous ASP334 and GLU319 in human non-gastric H,K- and Na,K-ATPases in cardiac glycoside binding

Keywords: mutagenesis مواجه با سایت; αHKng; α-subunit of the non-gastric H,K-ATPase; αHKg; α-subunit of the gastric H,K-ATPase; M4 M5; 4th, 5th transmembrane segments; H,K-ATPase; Na,K-ATPase; Cardiac steroid; Cardiac glycoside; Ouabain affinity; Site-directed mutagenesis;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2007 سفارش ترجمه

Enzymatic formation of unnatural cytokinin analogs by adenylate isopentenyltransferase from mulberry

Keywords: mutagenesis مواجه با سایت; Adenylate isopentenyltransferase; Cytokinin; Site-directed mutagenesis; Substrate specificity; Unnatural cytokinin; Biosynthesis

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

Enhanced transaminase activity of a bifunctional l-aspartate 4-decarboxylase

Keywords: mutagenesis مواجه با سایت; Asd, l-aspartate 4-decarboxylase; AT, aminotransferase; PLP, pyridoxal 5′-phosphate; α-KG, α-ketoglutarate; HPLC, high performance liquid chromatography; CD, circular dichroisml-Aspartate 4-decarboxylase; Aminotransferase; Site-directed mutagenesis; Kinet

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

Mutagenesis of non-conserved active site residues improves the activity and narrows the specificity of human thymidine kinase 2

Keywords: mutagenesis مواجه با سایت; Human thymidine kinase 2; Site-directed mutagenesis; Deoxyribonucleoside kinase; Nucleoside analog

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

Development of a rat parathyroid hormone 2 receptor antagonist

Keywords: mutagenesis مواجه با سایت; Peptide antagonist; Site-directed mutagenesis; Tuberoinfundibular peptide of 39 residues; Parathyroid hormone 2 receptor

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

Importance of threonine residues in the regulation of peanut serine/threonine/tyrosine protein kinase activity

Keywords: mutagenesis مواجه با سایت; Dual-specificity protein kinase; Regulation of kinase activity; Threonine residues; Site-directed mutagenesis; Arachis hypogaea

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

Refolding of human β-1-2 GlcNAc transferase (GnT1) and the role of its unpaired Cys 121

Keywords: mutagenesis مواجه با سایت; Human GnT1; Refolding; Oxido-shuffling; Cysteines; Site-directed mutagenesis

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

Functional analysis of a histone deacetylase-like protein of Thermus caldophilus GK24 in mammalian cell

Keywords: mutagenesis مواجه با سایت; Histone deacetylase; Thermus caldophilus GK24; Angiogenesis; Tca HDAC; Site-directed mutagenesis;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

A single amino acid in the PSPG-box plays an important role in the catalytic function of CaUGT2 (Curcumin glucosyltransferase), a Group D Family 1 glucosyltransferase from Catharanthus roseus

Keywords: mutagenesis مواجه با سایت; Glucosyltransferase; Curcumin; PSPG-box; Catalytic function; Domain swapping; Site-directed mutagenesis

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

Analysis of acidic surface of Haloferax mediterranei glucose dehydrogenase by site-directed mutagenesis

Keywords: mutagenesis مواجه با سایت; Glucose dehydrogenase structure; Halophilic proteins; Site-directed mutagenesis; Archaea; ThermostabilityGlcDH, glucose dehydrogenase; Hfx., Haloferax; Har., Haloarcula; Hbt., Halobacterium

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

N-Ethylmaleimide-resistant acyl-coenzyme A oxidase from Arthrobacter ureafaciens NBRC 12140: Molecular cloning, gene expression and characterization of the recombinant enzyme

Keywords: mutagenesis مواجه با سایت; Acyl-CoA oxidase; Arthrobacter sp.; N-ethylmaleimide-resistance; Cloning; Heterologous expression; Site-directed mutagenesis

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

Val326 of Thermoactinomyces vulgaris R-47 amylase II modulates the preference for alpha-(1,4)- and alpha-(1,6)-glycosidic linkages

Keywords: mutagenesis مواجه با سایت; Alpha-amylase; Subsite + 1; Transglycosylation; Substrate specificity; Site-directed mutagenesis; Oligosaccharide

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه