دانلود مقالات ISI درباره mutagenesis مواجه با سایت + ترجمه فارسی

Intermolecular interactions in staphylokinase-plasmin(ogen) bimolecular complex: Function of His43 and Tyr44

Keywords: mutagenesis مواجه با سایت; SAK; staphylokinase; SK; streptokinase; Pg; plasminogen; Pm; plasmin; μPm; microplasmin; Ees; electrostatic energy; Evdw; Van der Waals energy; Staphylokinase; Plasminogen-activation; Molecular-modeling; Site-directed mutagenesis; Enzyme-substrate comp

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Transmembrane helix 7 in the Na+/dicarboxylate cotransporter 1 is an outer helix that contains residues critical for function

Keywords: mutagenesis مواجه با سایت; DASS; divalent anion sodium symporter family; MTSEA-biotin; N-biotinaminoethyl methanethiosulfonate; MTSET; [2-(trimethylammonium)ethyl]-methanethiosulfonate; NaDC1; sodium dicarboxylate cotransporter 1; PMSF; phenylmethylsulfonyl fluoride; rb; rabbit; SL

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Identification of putative residues involved in the accessibility of the substrate-binding site of lipoxygenase by site-directed mutagenesis studies

Keywords: mutagenesis مواجه با سایت; Olive lipoxygenase; Homology-modeling; Site-directed mutagenesis; Substrate-binding accessibility;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Mutagenesis and computer modeling studies of a GPCR conserved residue W5.43(194) in ligand recognition and signal transduction for CB2 receptor

Keywords: mutagenesis مواجه با سایت; AC; adenylyl cyclase; BGH; bovine growth hormone; cAMP; Cyclic adenosine monophosphate; CB1; cannabinoid receptor subtype 1; CB2; cannabinoid receptor subtype 2; CNS; central nervous system; DTT; dithiothreitol; GPCR; G protein-coupled receptor; HA; influ

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Contribution of K99 and D319 to substrate binding and catalysis in the saccharopine dehydrogenase reaction

Keywords: mutagenesis مواجه با سایت; Site-directed mutagenesis; Lysine synthesis; Saccharopine dehydrogenase; Kinetic mechanism; Chemical mechanism; Oxidative deamination

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Insight into the binding of the wild type and mutated alginate lyase (AlyVI) with its substrate: A computational and experimental study

Keywords: mutagenesis مواجه با سایت; Alginate lyase; AlyVI; Homology modeling; Docking; Site-directed mutagenesis; MD simulations;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Direct and continuous fluorescence-based measurements of Pyrococcus horikoshii DNA N-6 adenine methyltransferase activity

Keywords: mutagenesis مواجه با سایت; DNA N-6 adenine methyltransferase; Pyrococcus horikoshii; Methylation assay; DNA duplex destabilisation; Site-directed mutagenesis

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Effects of human serum albumin complexed with free fatty acids on cell viability and insulin secretion in the hamster pancreatic β-cell line HIT-T15

Keywords: mutagenesis مواجه با سایت; Human serum albumin; Free fatty acid; HIT-T15 cell; Insulin secretion; Cell viability; In vitro protein expression; Site-directed mutagenesis; ADIFAB

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

The TSP motif in AP180 inhibits phospholipase D1 activity resulting in increased efficacy of anticancer drug via its direct binding to carboxyl terminal of phospholipase D1

Keywords: mutagenesis مواجه با سایت; Phospholipase D1; Assembly protein 180; Site-directed mutagenesis; Peptidomimetic drug; Cancer

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

cDNA cloning of an alginate lyase from a marine gastropod Aplysia kurodai and assessment of catalytically important residues of this enzyme

Keywords: mutagenesis مواجه با سایت; Aplysia; Alginate lyase; cDNA cloning; Polysaccharide-lyase-family 14; Site-directed mutagenesis;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

Effect of inactivation of genes involved in ammonium regulation on the biohydrogen production of Rhodobacter capsulatus

Keywords: mutagenesis مواجه با سایت; Rhodobacter capsulatus; Biohydrogen; GlnB/GlnK proteins; Ammonium inhibition; Site-directed mutagenesis; Kinetic modelling

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

Structural features of adenosine receptors: From crystal to function

Keywords: mutagenesis مواجه با سایت; G protein-coupled receptor; Heptahelical transmembrane protein; 7-TM; Adenosine receptor; Signal transduction; Structure; Site-directed mutagenesis

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2011 سفارش ترجمه

Interstitial Contacts in an RNA-Dependent RNA Polymerase Lattice

Keywords: mutagenesis مواجه با سایت; 3-D, three-dimensional; HCV, hepatitis C virusmacromolecular assembly; molecular modeling; protein oligomerization; site-directed mutagenesis; electron microscopy

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2011 سفارش ترجمه

Allosteric modulation of metabotropic glutamate receptors: Structural insights and therapeutic potential

Keywords: mutagenesis مواجه با سایت; Allosteric modulator; Chimeric receptors; G protein-coupled receptors; Neuromodulation; Site-directed mutagenesis; Homology modelADX47273, S-(4-fluoro-phenyl)-{3-[3-(4-fluoro-phenyl)-[1,2,4]oxadiazol-5-yl]-piperidin-1-yl}-methanone; AMN082, N,N’-Bis(diphe

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2011 سفارش ترجمه

A QuikChange-like method to realize efficient blunt-ended DNA directional cloning and site-directed mutagenesis simultaneously

Keywords: mutagenesis مواجه با سایت; QuikChange kit; Site-directed mutagenesis; Blunt-ended DNA ligation; Mutant library

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2010 سفارش ترجمه

Assemblies of semiconductor quantum dots and light-harvesting-complex II

Keywords: mutagenesis مواجه با سایت; Semiconductor quantum dots; Fluorescence quenching; Light-harvesting complex; Site-directed mutagenesis;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2010 سفارش ترجمه

Analysis of functional consequences of haplogroup J polymorphisms m.4216T > C and m.3866T > C in human MT-ND1: Mutagenesis of homologous positions in Escherichia coli

Keywords: mutagenesis مواجه با سایت; NADH dehydrogenase; Complex I deficiency; Mitochondrial DNA; Site-directed mutagenesis

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2010 سفارش ترجمه

Catalytic properties of thimet oligopeptidase H600A mutant

Keywords: mutagenesis مواجه با سایت; EP24.15; Substrate and inhibitor specificity; Site-directed mutagenesis; Thimet oligopeptidaseTOP, thimet oligopeptidase; Dcp, E. coli dipeptidyl carboxypeptidase; ACE-2, angiotensin-converting enzyme (ACE)-related carboxypeptidase; MLN-4760, ((S,S)-2-(1-

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

Amino acid residues involved in organic solvent-stability of the LST-03 lipase

Keywords: mutagenesis مواجه با سایت; Lipase; Organic solvent-stability; Site-directed mutagenesis; Salt bridge; Hydrogen bond

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

Structure-based engineering of benzalacetone synthase

Keywords: mutagenesis مواجه با سایت; Polyketide synthase; Benzalacetone synthase; Enzyme; Site-directed mutagenesis; Enzyme engineeringBAS, benzalacetone synthase; CHS, chalcone synthase; PKS, polyketide synthase; STS, stilbene synthase; BNY, bisnoryangonin; CTAL, 4-coumaroyltriacetic acid l

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

A role of Histidine151 in the lamprey gonadotropin-releasing hormone receptor-1 (lGnRHR-1): Functional insight of diverse amino acid residues in the position of Tyr of the DRY motif in GnRHR from an ancestral type II receptor

Keywords: mutagenesis مواجه با سایت; GnRH receptor; DRY motif; Receptor expression; Signaling; Site-directed mutagenesis; Lamprey;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Relaxing the coenzyme specificity of 1,3-propanediol oxidoreductase from Klebsiella pneumoniae by rational design

Keywords: mutagenesis مواجه با سایت; 1,3-Propanediol oxidoreductase; Coenzyme specificity; Rational protein design; Computational alanine-scanning mutagenesis; Site-directed mutagenesis; Klebsiella pneumoniae

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Site-directed mutagenesis of an Aspergillus niger xylanase B and its expression, purification and enzymatic characterization in Pichia pastoris

Keywords: mutagenesis مواجه با سایت; Xylanase; Aspergillus niger; Site-directed mutagenesis; Pichia pastoris; Thermostability; Bioreactor

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Systematic deletion and site-directed mutagenesis of FHVB2 establish the role of C-terminal amino acid residues in RNAi suppression

Keywords: mutagenesis مواجه با سایت; Suppressor; RNAi; FHVB2; Site-directed mutagenesis; Sf21;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Mutagenesis of the Sauromatum guttatum alternative oxidase reveals features important for oxygen binding and catalysis

Keywords: mutagenesis مواجه با سایت; Q(H2); (reduced) ubiquinone; OG; octyl gallate; SHAM; salicylic hydroxamic acid; Alternative oxidase; Oxygen affinity; α-keto acid regulation; Structure-function relations; Site-directed mutagenesis; Schizosaccharomyces pombe mitochondria;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Expression and functional characterization of prephenate dehydrogenase from Streptococcus mutans

Keywords: mutagenesis مواجه با سایت; Prephenate dehydrogenase; Streptococcus mutans; MALDI-TOF; Size exclusion chromatography; Site-directed mutagenesis; Tyrosine

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Identification of activity related amino acid mutations of a GH9 termite cellulase

Keywords: mutagenesis مواجه با سایت; Termite; Cellulase; Activity; Site-directed mutagenesis

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Homology-based modeling of the Erwinia amylovora type III secretion chaperone DspF used to identify amino acids required for virulence and interaction with the effector DspE

Keywords: mutagenesis مواجه با سایت; Fire blight; Site-directed mutagenesis; Translocation;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Investigation of the role of conserved residues Ser13, Asn48 and Pro49 in the catalytic mechanism of the tau class glutathione transferase from Glycine max

Keywords: mutagenesis مواجه با سایت; CDNB, 1-chloro-2,4-dinitrobenzene; GSH, glutathione; GST, glutathione-S-transferase; G-site, GSH binding site; H-site, hydrophobic binding site; S-(p-nitrobenzyl)-glutathione, Nb-GSHHerbicide detoxification; Site-directed mutagenesis; Kinetic mechanism, T

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Functional role of charged residues in drosomycin, a Drosophila antifungal peptide

Keywords: mutagenesis مواجه با سایت; Antifungal defensin; Site-directed mutagenesis; Functional site; Insect

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Kinetic characterization of the Escherichia coli oligopeptidase A (OpdA) and the role of the Tyr607 residue

Keywords: mutagenesis مواجه با سایت; M3A subfamily; E. coli oligopeptididase A; Site-directed mutagenesis; FRET substrates

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Functional impact of serial deletions at the C-terminus of the human GABAρ1 receptor

Keywords: mutagenesis مواجه با سایت; GFP; LGIC; TM4; Site-directed mutagenesis; Xenopus oocytes

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Structural and functional evaluation of three well-conserved serine residues in tobacco acetohydroxyacid synthase

Keywords: mutagenesis مواجه با سایت; Acetohydroxyacid synthase; Tobacco; Conserved serine; Site-directed mutagenesis; Homology modelingAHAS, Acetohydroxyacid synthase; wtAHAS, Wild-type AHAS; CD, Circular dichroism; FAD, Flavine adenine dinucleotide; GST, Glutathione S-transferase; IPTG, Iso

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Bacillus subtilis CwlQ (previous YjbJ) is a bifunctional enzyme exhibiting muramidase and soluble-lytic transglycosylase activities

Keywords: mutagenesis مواجه با سایت; Cell wall; Peptidoglycan hydrolase; Bifunctional domain; Bacillus subtilis; Site-directed mutagenesis

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Ubiquinol-binding site in the alternative oxidase: Mutagenesis reveals features important for substrate binding and inhibition

Keywords: mutagenesis مواجه با سایت; AOX, alternative oxidase; TAO, trypanosomal alternative oxidase; Q(H2), (reduced) ubiquinone; SHAM, salicylhydroxamic acidAlternative oxidase; Ubiquinone-binding; Structure–function relations; Site-directed mutagenesis; Schizosaccharomyces pombe mitochond

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Site-directed mutagenesis of charged amino acids of the human mitochondrial carnitine/acylcarnitine carrier: Insight into the molecular mechanism of transport

Keywords: mutagenesis مواجه با سایت; DTE; dithioerythritol; NEM; N-ethylmaleimide; Pipes; 1,4-piperazinediethanesulfonic acid; SDS-PAGE; sodium dodecyl sulfate polyacrylamide gel electrophoresis; CAC; carnitine/acylcarnitine carrier; WT; wild-type; Carnitine; Mitochondria; Transport; Site-di

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Targeting the cysteine-stabilized fold of Art v 1 for immunotherapy of Artemisia pollen allergy

Keywords: mutagenesis مواجه با سایت; Artemisia pollen allergy; Art v 1; Glycoallergen; Hypoallergen; Site-directed mutagenesis; Defensin; T cell epitope; Cysteine variants;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Model reactions for insect cuticle sclerotization: Participation of amino groups in the cross-linking of Manduca sexta cuticle protein MsCP36

Keywords: mutagenesis مواجه با سایت; Alanine; Catecholamine; Cross-link; Cuticle; Dityrosine; Histidine; Insect; Laccase; Lysine; Protein multimers; Sclerotization; Site-directed mutagenesis; Succinylation; Tyrosine

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Characterization and mutagenesis of a two-component monooxygenase involved in para-nitrophenol degradation by an Arthrobacter strain

Keywords: mutagenesis مواجه با سایت; Arthrobacter sp. strain NyZ415; para-Benzoquinone; para-Nitrophenol monooxygenase; Site-directed mutagenesis

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Antigenic domains analysis of classical swine fever virus E2 glycoprotein by mutagenesis and conformation-dependent monoclonal antibodies

Keywords: mutagenesis مواجه با سایت; Classical swine fever virus; E2 glycoprotein; Antigenic domain; Monoclonal antibodies; Site-directed mutagenesis

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Multiple ferredoxin isoforms in Chlamydomonas reinhardtii – Their role under stress conditions and biotechnological implications

Keywords: mutagenesis مواجه با سایت; anaerobiosis; Chlamydomonas; ferredoxin; hydrogenase; photosynthesis; protein–protein interaction; site-directed mutagenesis

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Cysteine 351 is an essential nucleophile in catalysis by Porphyromonas gingivalis peptidylarginine deiminase

Keywords: mutagenesis مواجه با سایت; Peptidylarginine deiminase; Porphyromonas gingivalis; Chemical modification; Site-directed mutagenesis; Cysteine

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Site-directed mutagenesis, purification and assay of Saccharomyces cerevisiae RNA polymerase II

Keywords: mutagenesis مواجه با سایت; RNA polymerase II; Saccharomyces cerevisiae; Site-directed mutagenesis; Fork loop 2 region; Transcription factor IIS

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Increase in thermal stability of Moloney murine leukaemia virus reverse transcriptase by site-directed mutagenesis

Keywords: mutagenesis مواجه با سایت; AMV, avian myeloblastosis virus; MMLV, Moloney murine leukaemia virus; RT, reverse transcriptase; T/P, template–primer; TCA, trichloroacetic acidcDNA synthesis; Moloney murine leukaemia virus; Reverse transcriptase; Site-directed mutagenesis; Stability

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Novel intracellular GH10 xylanase from Cohnella laeviribosi HY-21: Biocatalytic properties and alterations of substrate specificities by site-directed mutagenesis of Trp residues

Keywords: mutagenesis مواجه با سایت; Cohnella laeviribosi HY-21; Intracellular GH10 xylanase; Site-directed mutagenesis; Transxylosylation; Xylooligosaccharides

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Identification of antigen-specific residues on E2 glycoprotein of classical swine fever virus

Keywords: mutagenesis مواجه با سایت; Classical swine fever virus; E2 glycoprotein; Antigenic specificity; Monoclonal antibodies; Site-directed mutagenesis

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Molecular cloning and functional characterization of caspase 9 in large yellow croaker (Pseudosciaena crocea)

Keywords: mutagenesis مواجه با سایت; Large yellow croaker (Pseudosciaena crocea); Caspase 9; Site-directed mutagenesis; Proteolytic activity; Expression modulation

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Functional analysis of Pcpme6 from oomycete plant pathogen Phytophthora capsici

Keywords: mutagenesis مواجه با سایت; Oomycete; Phytophthora capsici; Methylesterase; Virulent protein; Site-directed mutagenesis; Pathogenesis

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Effects of the mutational combinations on the activity and stability of thermolysin

Keywords: mutagenesis مواجه با سایت; FAGLA, N-[3-(2-furyl)acryloyl]-glycyl-l-leucine amide; ZDFM, N-carbobenzoxy-l-aspartyl-l-phenylalanine methyl esterActivity–stability relationship; Mutational combination; Site-directed mutagenesis; Thermal stability; Thermolysin

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

Functional analysis and mode of action of phytotoxic Nep1-like proteins of Botrytis cinerea

Keywords: mutagenesis مواجه با سایت; Gene expression; Grey mould; Necrotroph; Phytotoxic proteins; Site-directed mutagenesis; Virulence factor

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2010 سفارش ترجمه