Keywords: kinase family Src; ATP; adenosine triphosphate; CBX; carbenoxolone; C-terminus; carboxyl-terminus; CNS; central nervous system; EL; extracellular loop; Gly0; core glycosylation; Gly1; high mannose glycosylation; Gly2; complex glycosylation; ICL; intracellular loop; N2a; Neu
مقالات ISI kinase family Src (ترجمه نشده)
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Keywords: kinase family Src; ALL; acute lymphoblastic leukemia; AML; acute myeloid leukemia; CLL; B-cell chronic lymphocytic leukemia; CML; chronic myelogenous leukemia; ERK; extracellular signal-regulated kinase; FN3; fibronectin type-III (domain); GBM; glioblastoma multiforme; JMML
Keywords: kinase family Src; BM; basement membrane; ECM; extracellular matrix; EMT; epithelial-mesenchymal transition; FA; focal adhesion; HD; hemidesmosome; IAP; integrin associated protein; RTK; receptor tyrosine kinase; SFK; Src family kinase; TEM; tetraspanin-enriched microdomain
Keywords: kinase family Src; 5-hydroxytryptamine; Tryptophan Hydroxylase; 5-HT2B; Pancreatic Intraepithelial Neoplasia; 5-HT; serotonin (5-hydroxytryptamine); CT; computed tomography; ECAR; extracellular acid ratio; HTRs; 5-HT receptors; KPC; KrasG12D/+/Trp53R172H/+/Pdx1-Cre; IHC; im
Keywords: kinase family Src; AMP-activated protein kinase; Glycogen synthase kinase 3; Src family kinase; Signaling pathway; Sperm function
Keywords: kinase family Src; ALI; acute lung injury; ECM; extracellular matrix; EGFR; epidermal growth factor receptor; LPS; lipopolysaccharide; MMP; matrix metalloproteinase; NRTK; nonreceptor tyrosine kinase; PDGF; platelet-derived growth factor; PDGFR; platelet-derived growth fact
Transforming growth factor-β1 impairs lymph node homing of dendritic cells by downregulating C-type lectin receptor-2 expression
Keywords: kinase family Src; c-Src; C-type lectin receptor; Dendritic cell trafficking; Immunosuppressive cytokines; BMDC; bone marrow-derived dendritic cell; Btk; Bruton's tyrosine kinase; CLEC-2; C-type lectin receptor-2; DC; dendritic cell; GM-CSF; granulocyte-macrophage colony-
Src family kinase tyrosine phosphorylates Toll-like receptor 4 to dissociate MyD88 and Mal/Tirap, suppressing LPS-induced inflammatory responses
Keywords: kinase family Src; BMMCs; bone marrow-derived mast cells; Csk; C-terminal Src kinase; IRF; IFN-regulated factor; Mal; myeloid differentiation factor 88 (MyD88)-adapter-like; SFK; Src-family kinase; TIR domain; Toll/IL-1R (TIR) domain; Tirap; toll-interleukin 1 receptor (TIR
Leveraging Siglec-8 endocytic mechanisms to kill human eosinophils and malignant mast cells
Keywords: kinase family Src; Siglec-8; endocytosis; eosinophil; mast cell; allergic diseases; chronic eosinophilic leukemia; systemic mastocytosis; immunotoxin; targeting; BIM; Bisindolylmaleimide I; DAPI; 4â²-6-Diamidino-2-phenylindole; ITIM; Immunoreceptor tyrosine-based inhibitor
Dual Inhibition of Mnk2 and FLT3 for potential treatment of acute myeloid leukaemia
Keywords: kinase family Src; Mnk inhibitor; FLT3 inhibitor; Dual inhibitor; AML; Drug discovery; Anti-leukaemic agent; AML; acute myeloid leukaemia; CDK; cyclin-dependent kinase; eIF; eukaryotic initiation factor; Erk; extracellular signal-regulated kinase; FLT3; Fms-like tyrosine ki
As human lung microvascular endothelia achieve confluence, src family kinases are activated, and tyrosine-phosphorylated p120 catenin physically couples NEU1 sialidase to CD31
Keywords: kinase family Src; aa; amino acid; Ad; adenovirus; CD; cytoplasmic domain; EC; endothelial cell; ECL; enhanced chemiluminescence; EGFR; epidermal growth factor receptor; GST; glutathione S-transferase; HPMEC; human pulmonary microvascular endothelial cell; HRP; horseradish
Selective Targeting of SH2 Domain-Phosphotyrosine Interactions of Src Family Tyrosine Kinases with Monobodies
Keywords: kinase family Src; SH2; Src homology 2 domain; pY; phosphotyrosine; SFK; Src family kinase; ITC; isothermal titration calorimetry; TAP; tandem affinity purification; LC-MS/MS; liquid chromatography coupled to tandem mass spectrometry; TAP-MS; TAP-mass spectrometry; TEV; t
Histone methyltransferase SETDB1 maintains survival of mouse spermatogonial stem/progenitor cells via PTEN/AKT/FOXO1 pathway
Keywords: kinase family Src; SETDB1; set domain, bifurcated 1; H3K9; histone H3 lysine 9; SSCs; spermatogonial stem cells; GDNF; glial cell line-derived neurotrophic factor; SFK; Src family kinase; PI3K; phosphatidylinositol 3-kinase; ESCs; embryo stem cells; DMEM/F12; Modified Eagle
Role of Herpes simplex virus 1 VP11/12 tyrosine-based binding motifs for Src family kinases, p85, Grb2 and Shc in activation of the phosphoinositide 3-kinase-Akt pathway
Keywords: kinase family Src; Akt; Src family kinase; PI3 kinase; Herpesvirus; Tegument; Signaling;
Invited reviewFyn is an important molecule in cancer pathogenesis and drug resistance
Keywords: kinase family Src; Fyn; Cancer; Src family kinase; Drug resistance;
RTK SLAP DOWN: The emerging role of Src-like adaptor protein as a key player in receptor tyrosine kinase signaling
Keywords: kinase family Src; AML; acute myeloid leukemia; BCR; B cell receptor; BMM; bone marrow-derived macrophage; CSF-1R; colony stimulating factor-1 receptor; CRC; colorectal cancer; Flt3; Fms-like tyrosine kinase 3; NMDAR; N-methyl-D-aspartate receptor; PDGFR; platelet derived g
The intracerebroventricular injection of rimonabant inhibits systemic lipopolysaccharide-induced lung inflammation
Keywords: kinase family Src; ICV; intracerebroventricular; CB1; cannabinoid receptor type 1; LPS; lipopolysaccharide; IV; intravenous; Ppc; pulmonary capillary pressure; TLR4; toll-like receptor 4; IRAK1; interleukin receptor-associated kinase-1; IκBα; inhibitor of nuclear factor o
Damage to lens fiber cells causes TRPV4-dependent Src family kinase activation in the epithelium
Keywords: kinase family Src; Lens epithelium; Lens fiber; Na,K-ATPase activity; Remote sensing; Src family kinase; TRPV4 channel;
C3G (RapGEF1), a regulator of actin dynamics promotes survival and myogenic differentiation of mouse mesenchymal cells
Keywords: kinase family Src; GM; growth medium; DM; differentiation medium; GEF; guanine nucleotide exchange factor; MHC; myosin heavy chain; CBR; Crk binding region; ShRNA; small hairpin RNA; FAs; focal adhesions; SFK; Src family kinase; Cl-casp-3; cleaved caspase-3; Dn; dominant ne
Tyrosine phosphorylation of the orphan receptor ESDN/DCBLD2 serves as a scaffold for the signaling adaptor CrkL
Keywords: kinase family Src; ESDN; endothelial and smooth muscle cell-derived neuropilin-like protein; DCBLD2; discoidin CUB and LCCL domain containing 2; CUB; complement C1r/C1s Uegf Bmp1; CrkL; CrkCT10 regulator of kinase Crk-Like; SFK; Src family tyrosine kinase; Cas; Crk-associat
Crystal structure of Src-like adaptor protein 2 reveals close association of SH3 and SH2 domains through β-sheet formation
Keywords: kinase family Src; βME; β-mercaptoethanol; CrkL; Crk-like; DTT; dithiothreitol; Itk; interleukin-2 tyrosine kinase; SLAP; Src-like adaptor protein; SFK; Src family kinase; SH; Src-homology; SDS-PAGE; sodium dodecyl sulfate polyacrylamide gel electrophoresis; TCR; T cell r
Tau protein phosphatases in Alzheimer's disease: The leading role of PP2A
Keywords: kinase family Src; AD; Alzheimer's disease; NFT; neurofibrillary tangles; PHF; paired helical filaments; SP; senile plaques; APP; apolipoprotein; PP1; protein phosphatase-1; PP2A; protein phosphatase-2A; PP2B; protein phosphatase-2B; PP5; protein phosphatase-5; PTEN; phosph
The COOH-terminus of TM4SF5 in hepatoma cell lines regulates c-Src to form invasive protrusions via EGFR Tyr845 phosphorylation
Keywords: kinase family Src; ICL; intracellular loop; SYF; c-Src-, Fyn-, and Yes-negative mouse embryonic fibroblasts; SYF++; c-Src-reconstituted SYF cells; SFKs; c-Src family kinases; TERM; tetraspanin-enriched microdomain; TM4SF5; Transmembrane 4 L6 family member 5; TM4SF5ÎC; COOH
TNF-α-mediated bronchial barrier disruption and regulation by src-family kinase activation
Keywords: kinase family Src; Airway; bronchial; barrier; epithelial; TNF-α; cytokines; proMMP-9; src kinase; SU6656; AJ; Adherens junctions; ALI; Air-liquid interface; ECL; Electrochemiluminescence; EVOM; Epithelial volt ohm meter; FITC; Fluorescein isothiocyanate; HBEC; Human bronc
Tau protein kinases: Involvement in Alzheimer's disease
Keywords: kinase family Src; AD; Alzheimer's disease; APP; amyloid precursor protein; Arg; Abl-related gene; SFK; Src family kinase; Aβ; β-amyloid; BBB; blood brain barrier; LD50; lethal dose 50; c-Abl; c-Abelson; Cables; c-Abl-binding adaptator protein; CaMKII; Ca2+/calmodulin-dep
CB1 cannabinoid receptors promote maximal FAK catalytic activity by stimulating cooperative signaling between receptor tyrosine kinases and integrins in neuronal cells
Keywords: kinase family Src; 2-AG; 2-arachidonoylglycerol; BSA; bovine serum albumin; CB1; CB1 cannabinoid receptor; Csk; C-terminal Src kinase; DAGL; diacylglycerol lipase; DTT; dithiothreitol; ECM; extracellular matrix; ERK1/2; extracellular signal-regulated kinases 1 and 2; EGFR;
Simultaneous inhibition of Src and Aurora kinases by SU6656 induces therapeutic synergy in human synovial sarcoma growth, invasion and angiogenesis in vivo
Keywords: kinase family Src; Src family kinase; Aurora kinases; SU6656; Synergy; Synovial sarcoma;
Fluorine-labeled Dasatinib Nanoformulations as Targeted Molecular Imaging Probes in a PDGFB-driven Murine Glioblastoma Model
Keywords: kinase family Src; RTK; receptor tyrosine kinase; PDGFR; platelet-derived growth factor receptor; PDGFB; platelet-derived growth factor B; SFK; Src family kinase; BMS354825; dasatinib, free base; SKI249380; dasatinib; mGBM; murine glioblastoma multiforme;
Extracellular ATP stimulates epithelial cell motility through Pyk2-mediated activation of the EGF receptor
Keywords: kinase family Src; EGFR; epidermal growth factor receptor; SFK; Src family kinase; FAK; focal adhesion kinase; Pyk2; proline-rich tyrosine kinase 2; HCLE; human corneal limbal epithelial; SKI; Src Kinase Inhibitor-I; siRNA; small interfering RNA; PRNK; Pyk2-related non-kina
Serine phosphorylation regulates disabled-1 early isoform turnover independently of Reelin
Keywords: kinase family Src; ApoER2; apolipoprotein E receptor 2; CsA; cyclosporine A; Cdk; cyclin dependent kinase; Dab1; Disabled-1; CHX; cycloheximide; CPTS; 3,4',4â³,4-copper phthalocyanine tetrasulfonic acid, tetrasodium salt; CsA; cyclosporine A; ED; embryonic day; GSK3; glyco
Involvement of Src family kinase activation in angiotensin II-induced hyperresponsiveness of rat bronchial smooth muscle
Keywords: kinase family Src; Airway hyperresponsiveness; Angiotensin II; Src family kinase; Bronchial smooth muscle
Significance of glycosphingolipid fatty acid chain length on membrane microdomain-mediated signal transduction
Keywords: kinase family Src; Glycosphingolipid; Fatty acid chain; Microdomain; Src family kinase
The oncogenic activity of the Src family kinase Hck requires the cooperative action of the plasma membrane- and lysosome-associated isoforms
Keywords: kinase family Src; Proto-oncogene Hck; Src family kinase; Podosome; Phagocytes; Chronic myeloid leukaemia;
Expression of multiple Src family kinases in sea urchin eggs and their function in Ca2+ release at fertilization
Keywords: kinase family Src; Src family kinase; Fertilization; Development; Sea urchin; Signal transduction
Zinc and cortical plasticity
Keywords: kinase family Src; 5-HT; 5-hydroxytryptamine; ADP; adenosine diphosphate; AD; Alzheimer's disease; AMPA; α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid; ATP; adenosine triphosphate; BDNF; brain derived neurotrophic factor; Ca-EDTA; calcium ethylenediaminetetraacetic
Src family kinases promote AML cell survival through activation of signal transducers and activators of transcription (STAT)
Keywords: kinase family Src; Src family kinase; STAT5; Akt
The inhibition of tube formation in a collagen–fibrinogen, three-dimensional gel by cleaved kininogen (HKa) and HK domain 5 (D5) is dependent on Src family kinases
Keywords: kinase family Src; Angiogenesis; C-terminal Srk kinases; uPAR; αvβ3; Integrin; Src family kinase; Kininogen
The development of 2-benzimidazole substituted pyrimidine based inhibitors of lymphocyte specific kinase (Lck)
Keywords: kinase family Src; Kinase; Lck; Hck; Lymphocyte specific kinase; Hematopoietic cell kinase; Src family kinase; T cell
SRC family kinase inhibitor SU6656 enhances antiangiogenic effect of irradiation
Keywords: kinase family Src; Src family kinase; SFK; SU6656; Angiogenesis; Radiosensitizer;
Docking protein Gab2 positively regulates glycoprotein VI-mediated platelet activation
Keywords: kinase family Src; Gab2; Glycoprotein VI; Blood platelets; PLCγ2; Src family kinase; Protein tyrosine phosphorylation;
Regulation of Src kinase activity during Xenopus oocyte maturation
Keywords: kinase family Src; CSF; cytostatic factor; GVBD; germinal vesicle breakdown; IP3; inositol 1,4,5-trisphosphate; MAPK; mitogen-activated protein kinase; MPF; maturation-promoting factor; PI3K; phosphatidylinositol 3-kinase; PKA; cAMP-dependent protein kinase; PLC; phospholip
Signaling by Kit protein-tyrosine kinase-The stem cell factor receptor
Keywords: kinase family Src; Akt; APS; Bad; Cancer; Cbl; Dok1; Erk; Fyn; Grb2; Grb7; Hematopoiesis; Leukemia cell lines; Lyn; MAP kinase; Mast cell; Oncogene; Piebaldism; Protein kinase; Protein phosphatase; Proto-oncogene; Ras; Shp1; Shp2; Src family kinase;