Keywords: ABC; ATP-binding cassette; AKT; V-Akt murine thymoma viral oncogene homolog; ALDH1; aldehyde dehydrogenase 1; AR; androgen receptor; Bad; Bcl-2-associated death promoter; Bak; Bcl-2 homologous antagonist killer; Bax; Bcl-2-associated X protein; Bcl-2; B-c
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Keywords: ALK; anaplastic lymphoma receptor tyrosine kinase; ABCB1; ATP-binding cassette, sub-family B (MDR/TAP), member 1; APE1; apurinic/apyimidinic endonuclease 1; AKT; v-akt murine thymoma viral oncogene; BER; base excision repair; BRCA1; breast cancer 1; BRCA2
Keywords: Crystalline lens; Ionizing radiation; DNA repair factors; Nontargeted effects; Inflammation; Tumor suppressors; A-bomb; atomic-bomb; Acvr1; activin A type 1 receptor; AP; apurinic/apyrimidinic; APE1; apurinic/apyrimidinic endonuclease 1; AQP; aquaporin; A
Keywords: 4-HPR; N-(4-hydroxyphenyl)retinamide; 5â²-UTR; 5â²-untranslated region; 9-cis-RA; 9-cis retinoic acid; 9cUAB30; (2E,4E,6Z,8E)-8-(3â²,4â²-dihydro-1â²(2'H)-naphthalen-1â²-ylidene)-3,7-dimethyl-2,4,6-octatrienoic acid; Acitretin; (2E,4E,6E,8E)-9-(4-met
CCRK is a novel signalling hub exploitable in cancer immunotherapy
Keywords: 9G8; serine and arginine rich splicing factor 7; AKT; AKT serine/threonine kinase; AR; androgen receptor; ARE; androgen response element; ARG1; arginase 1; ATM; ataxia telangiectasia mutated; ATR; ataxia telangiectasia and rad3-related protein; BMDC; mous
DNA repair mechanisms in response to genotoxicity of warfare agent sulfur mustard
Keywords: ATM; ataxia telangiectasia mutated; ATR; ataxia telangiectasia and rad3 related; BER; base excision repair; Cdc25; cell division cycle 25; CDKs; cyclin-dependent kinases; CEES; 2-chloroethyl ethyl sulphide; ChK1; checkpoint kinase 1; Chk2; checkpoint kina
The matrix protein of vesicular stomatitis virus inhibits host-directed transcription of target genes via interaction with the TFIIH subunit p8
Keywords: VSV; Transcription inhibition; TFIIH; p8;
Two mammalian homologs of yeast Rad23, HR23A and HR23B, as multifunctional proteins
Keywords: HR23; homolog of Rad23; GG-NER; global genome nucleotide excision repair; XPC; xeroderma pigmentosum group C; UBL; ubiquitin-like; UBA; ubiquitin-associated; TFIIH; transcription factor IIH; DKO; double knockout; UIM; ubiquitin-interacting motif; HDAC; hi
Cytotoxic platinum coordination compounds. DNA binding agents
Keywords: 1,0,1/t,c,t; [{trans-PtCl(NH3)2}2μ-cis-Pt(NH3)2{H2N(CH2)6NH2}2]4+; 1,0,1/t,t,t; trans-PtCl(NH3)2}2μ-trans-Pt(NH3)2{H2N(CH2)6NH2}2]4+ (BBR3464); 1,1/c,c; [{cis-PtCl(NH3)2}2µ-{H2N(CH2)6NH2}]2+; 1,1/c,c,prz; [{cis-Pt(NH3)2}2(µ-OH)(µ-pyrazolato)]2+; 1,1/
Molecular mechanisms of DNA damage recognition for mammalian nucleotide excision repair
Keywords: 6-4PP; Pyrimidine (6-4) pyrimidone photoproduct; BHD; β-Hairpin domain; CAK; CDK-activating kinase; CPD; Cyclobutane pyrimidine dimer; CUL4; Cullin 4; HD; RecA-like helicase domain; NER; Nucleotide excision repair; RBX1; RING-box protein 1; TFIIH; Transc
XPA: A key scaffold for human nucleotide excision repair
Keywords: NER; nucleotide excision repair; XP; Xeroderma pigmentosum; TFIIH; transcription factor II H; RPA; replication protein A; WT; wild type; FL; full-length; AAF; N-(deoxyguanosin-8-yl)-2-acetylaminofluorene; (6-4)PP; (6-4)photoproduct; CPD; cyclobutane pyrim
Role of XPD in cellular functions: To TFIIH and beyond
Keywords: ANT2; an adenine nucleotide translocase that exchanges mitochondrial ATP with cytosolic ADP; CDK; cyclin dependent kinase; CAK; CDK-activating kinase complex; CIA; cytoplasmic FeS assembly; CIA01/2; cytosolic iron-sulfur assembly component ½; CS; Cockayn
Evolutionary conservation of TFIIH subunits: Implications for the use of zebrafish as a model to study TFIIH function and regulation
Keywords: CAK; CDK activating kinase; CDKs; cyclin-dependent kinases; NER; nucleotide excision repair; TFs; transcriptional factors; TFIIH; transcriptional factor IIH; XPB; xeroderma pigmentosum B; XPD; xeroderma pigmentosum D; Transcriptional factor IIH (TFIIH); X
Promoter clearance by RNA polymerase II
Keywords: Transcript initiation; Abortive initiation; Transcript elongation; TFIIB; TFIIH;
Functional insights into the core-TFIIH from a comparative survey
Keywords: TFIIH; Transcription; Repair; Splicing; Comparative genomic analysis; P34;
DNA repair mechanisms in dividing and non-dividing cells
Keywords: DNA repair; Neural cells; Neurological disorder; Dividing and non-dividing; Endogenous DNA damage; AOA1; ataxia with ocular motor apraxia 1; AP; apurinic/apyrimidinic; APE1; AP endonuclease 1; APTX; aprataxin; ATM; ataxia telangiectasia mutated; CPDs; cyc
Structural insights into transcription initiation by RNA polymerase II
Keywords: RNA polymerase II; transcription; preinitiation complex (PIC); open complex; translocase; TFIIH; mediator; SAGA; coactivators; TFIID
Trimethylation of histone H3K4 is associated with the induction of fructose-inducible genes in rat jejunum
Keywords: Cabp2; calcium binding protein 2; Cdkn1c; Cyclin-dependent kinase inhibitor 1c; ChIP; chromatin immunoprecipitation; CTD; C-terminal domain; G6pc; glucose-6-phosphatase; Gcgr; glucagon receptor; GCOS; GeneChip operating system; PolII; RNA polymerase II; R
Inducing local DNA damage by visible light to study chromatin repair
Keywords: Local DNA damage; Visible light; DNA breaks; H2AX phosphorylation; ATM; RPA; XRCC1; Lig III; PCNA; 8-oxodG; TFIIH
Effects of compound heterozygosity at the Xpd locus on cancer and ageing in mouse models
Keywords: AUC; area under the curve; CH; compound heterozygote; CS; Cockayne syndrome; GG-NER; global genome NER; IGF-1; insulin-like growth factor 1; IGF-1R; insulin-like growth factor receptor; IR; ionizing radiation; MDF; mouse dermal fibroblast; MEF; mouse embr
A history of TFIIH: Two decades of molecular biology on a pivotal transcription/repair factor
Keywords: TFIIH; Helicase; DNA repair; Genomic instability
The xeroderma pigmentosum pathway: Decision tree analysis of DNA quality
Keywords: DDB1; DDB2; ERCC1; RPA; TFIIH; UV-DDB; XPA; XPB; XPC; XPD; XPE; XPF; XPG
Improved methods for expression and purification of Saccharomyces cerevisiae TFIIF and TFIIH; Identification of a functional Escherichia coli promoter and internal translation initiation within the N-terminal coding region of the TFIIF TFG1 subunit
Keywords: S. cerevisiae; TFIIF; TFIIH; Transcription
Interacting partners of the Tfb2 subunit from yeast TFIIH
Keywords: TFIIH; NER; Transcription; TTD-A
Influence of the live cell DNA marker DRAQ5 on chromatin-associated processes
Keywords: TFIIH; XPB; RPA; TLS polymerases; NER; PCNA; Histones
A novel activity enhances promoter escape of RNA polymerase I
Keywords: Pol I; RNA polymerase I; TIF; transcription initiation factor; UBF; upstream binding factor; SL1; selectivity factor 1; TFIIH; transcription factor IIH; hRRN3; human rRNA synthesis defective 3; RPA116; RNA polymerase I subunit 116; TAF110; TBP-associated
The ubiquitin receptor Rad23: At the crossroads of nucleotide excision repair and proteasomal degradation
Keywords: CS; Cockayne syndrome; DUBs; deubiquitylation enzymes; ER; endoplasmic reticulum; ERAD; ER-associated degradation; GGR; global genomic NER; hHR23; human homologue Rad23; mHR23; murine homologue Rad23; NER; nucleotide excision repair; TFIIH; transcription
XPD structure reveals its secrets
Keywords: TFIIH; Xeroderma pigmentosum; Trichothiodystrophy; Helicase
Influence of XPB helicase on recruitment and redistribution of nucleotide excision repair proteins at sites of UV-induced DNA damage
Keywords: Xeroderma pigmentosum; Confocal microscopy; Helicase; TFIIH
Characterization of ERCC3 mutations in the Chinese hamster ovary 27-1, UV24 and MMC-2 cell lines
Keywords: Chinese hamster ovary; ERCC3 mutations; TFIIH; Nucleotide excision repair; XPB helicase
Cyclin-dependent kinase activating kinase/Cdk7 co-localizes with PKC-ι in human glioma cells
Keywords: PKC; protein kinase C; U-373MG; human glioma U-373MG cell line; GO/G1; quiescence/gap 1; S; DNA synthesis phase; G2M; gap 2 and mitosis; PBS; phosphate-buffered saline; DMSO; dimethyl sulfoxide; PI; propidium iodide; EDTA; ethylenediamine-tetraacetic acid
Two New XPD Patients Compound Heterozygous for the Same Mutation Demonstrate Diverse Clinical Features
Keywords: Cockayne syndrome; DNA repair; mutation; TFIIH; xeroderma pigmentosum;
An easy approach for the purification of native TFIIH
Keywords: Transcription; TFIIH; General transcription factors; Purification;
Functional XPB/RAD25 redundancy in Arabidopsis genome: characterization of AtXPB2 and expression analysis
Keywords: (6-4) PPs; pyrimidine (6-4) pyrimidone photoproduct; 5â²UTR; 5â² untranslated region; bp; base pair; cDNA; DNA complementary to RNA; Col; Columbia ecotype; CPD; cyclobutane pyrimidine dimer; Ler; Landsberg erecta ecotype; NER; nucleotide excision repair
The yeast rDNA locus: A model system to study DNA repair in chromatin
Keywords: CHO; Chinese hamster ovary; CPDs; cyclobutane pyrimidine dimers; CS; Cockayne syndrome; CSB; CS group B; DAHC; histone deacetylases; FACT; facilitates chromatin transcription; GGR; global genomic repair; HAT; histone acetyltransferases; ISWI; imitation sw
Nucleotide excision repair in chromatin and the right of entry
Keywords: Histones; Transcription coupled repair; Cyclobutane pyrimidine dimer; Designed nucleosomes; CPD; cyclobutane pyrimidine dimer; 6-4PPs; 6-4 photoproducts; AAF-G; acetylaminofluorene-guanine adduct; GGR; global genomic repair; NER; nucleotide excision repai