Keywords: Tg، ترانس ژنیک; CNS, central nervous system; C4ST, chondroitin 4-O-sulfotransferase; C6ST, chondroitin 6-O-sulfotransferase; CS, chondroitin sulfate; TG, transgenic; PG, proteoglycan; GABA, γ-aminobutyric acid; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; Narp, neuro
مقالات ISI Tg، ترانس ژنیک (ترجمه نشده)
مقالات زیر هنوز به فارسی ترجمه نشده اند.
در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Keywords: Tg، ترانس ژنیک; rhIFNβ, recombinant human interferon beta; hIFNβ, human interferon beta; i.p., intraperitoneally; LU, laboratory units; MS, multiple sclerosis; ELISA, enzyme linked immunosorbent assay; HSA, human serum albumin; Tg, transgenic; non-Tg, non-transgenic; PCR
Keywords: Tg، ترانس ژنیک; WT, wild type; Tg, transgenic; pSTR, positive scotopic threshold response; ERG, electroretinogram; IOP, intraocular pressure; GCL, ganglion cell layer; IPL, inner plexiform layer; AD, Alzheimer’s disease; APP, amyloid precursor protein; PSEN, presenilineA
Keywords: Tg، ترانس ژنیک; EBF2; Beige fat; Brown fat; Obesity; ThermogenesisBAT, brown adipose tissue; WAT, white adipose tissue; ingWAT, inguinal white adipose tissue; epiWAT, epididymal white adipose tissue; WT, wild type; TG, transgenic; HFD, high fat diet; TN, thermoneutrality
Keywords: Tg، ترانس ژنیک; IF, intermediate filament; NSCs, neural stem cells; NPCs, neural progenitor cells; E8.5, embryonic day 8.5; WT, wild type; TG, transgenic; PI3K, phosphoinositide 3-kinaseNestin; Embryonic development; Heart; Forebrain; Cell proliferation; PI3K/Akt pathway
Elevated VEGF-D Modulates Tumor Inflammation and Reduces the Growth of Carcinogen-Induced Skin Tumors 1
Keywords: Tg، ترانس ژنیک; cSCC, cutaneous squamous cell carcinoma; DMBA, 7,12-dimethylbenz[a]anthracene; IFN, interferon; IL, interleukin; K14, keratin 14; KO, knockout; LN, lymph node; NMSC, non-melanoma skin cancer; TG, transgenic; TGF, transforming growth factor; TNF, tumor nec
Role of extrahepatic UDP-glucuronosyltransferase 1A1: Advances in understanding breast milk-induced neonatal hyperbilirubinemia
Keywords: Tg، ترانس ژنیک; BMJ, breast milk jaundice; UGT, UDP-glucuronosyltransferase; hUGT1, humanized UGT1; Tg, transgenic; OATP, organic anion transporting polypeptide; OAT, organic anion transporter; ER, endoplasmic reticulum, MRP2, multidrug resistance protein 2; AAP, America
Deciphering metabolic abnormalities associated with Alzheimer's disease in the APP/PS1 mouse model using integrated metabolomic approaches
Keywords: Tg، ترانس ژنیک; Metabolomics; APP/PS1 mice; Alzheimer's disease; SerumAD, Alzheimer's disease; GC–MS, gas chromatography mass spectrometry; UHPLC-MS, ultra-high performance liquid chromatography mass spectrometry; TG, transgenic; WT, wild type; QC, quality control; PCA,
Hormonal milieu at time of B cell activation controls duration of autoantibody response
Keywords: Tg، ترانس ژنیک; B cells; anti-DNA antibody; Autoantibodies; AutoreactiveSLE, systemic lupus erythematosus; T, transitional; Tg, transgenic; κ, kappa; MZ, marginal zone; Fo, follicular; E2, estradiol; Pr, prolactin; P, placebo
Early-onset cognitive deficits and axonal transport dysfunction in P301S mutant tau transgenic mice
Keywords: Tg، ترانس ژنیک; NFTs, neurofibrillary tangles; FTLD, frontotemporal lobar degeneration; MT, microtubule; WT, wild type; Tg, transgenic; SEM, standard error of the meanTau; Axonal transport; Tg mouse model; Neurofibrillary tangles; Frontotemporal lobar degeneration; Alzhe
Intrinsic defects in CD8 T cells with aging contribute to impaired primary antiviral responses
Keywords: Tg، ترانس ژنیک; Tg, transgenic; LCMV, lymphocytic choriomeningitis virus; MFI, mean fluorescence intensityT cells; Viral; Intrinsic; Defect; Aging
Modulation of semaphorin3A in perineuronal nets during structural plasticity in the adult cerebellum
Keywords: Tg، ترانس ژنیک; CSPG, chondroitin sulfate proteoglycan; ECM, extracellular matrix; DCN, deep cerebellar nuclei; PC, Purkinje cell; PI, propidium iodidie; PNN, perineuronal net; Sema3A, semaphorin3A; TG, transgenic; WFA, Wisteria floribunda agglutinin; WT, wild-typePerine
NAP (davunetide) modifies disease progression in a mouse model of severe neurodegeneration: Protection against impairments in axonal transport
Keywords: Tg، ترانس ژنیک; ALS, amyotrophic lateral sclerosis; SOD1, superoxide dismutase 1; SOD1-G93A, mutated SOD1; Tg, transgenic; MT, microtubule; VTA, ventral tegmental area; FTD, frontotemporal dementia; ADNP, activity dependent neuroprotective protein; FDR, false discovery r
Mutant laboratory mice with abnormalities in hair follicle morphogenesis, cycling, and/or structure: An update
Keywords: Tg، ترانس ژنیک; ENU, ethyl-nitrosourea induced chemical mutagenesis; GEMs, genetically engineered mice; HF, hair follicle; Rad, radiation induced; S, spontaneous mutation; Tg, transgenic; TGF, transforming growth factor; Tm, targeted mutationHair follicle morphogenesis;
Ibuprofen ameliorates protein aggregation and astrocytic gliosis, but not cognitive dysfunction, in a transgenic mouse expressing dementia with Lewy bodies-linked P123H β-synuclein
Keywords: Tg، ترانس ژنیک; PD, Parkinson's disease; AD, Alzheimer's disease; DLB, dementia with Lewy bodies; tg, transgenic; β-syn, β-synuclein; α-syn, α-synuclein; NSAIDs, nonsteroidal anti-inflammatory drugs; GFAP, glial fibrillary acidic protein; qPCR, quantitative polymerase ch
Modulation of TCRβ surface expression during TCR revision
Keywords: Tg، ترانس ژنیک; B6, C57BL/6; Mtv-8, mouse mammary tumor virus-8; Tg, transgenic; nonTg, nontransgenic; TBST, Tris-buffered saline + 0.1% Tween 20; s, surface; e, endogenous; HPRT, Hypoxanthine guanine phosphoribosyltransferaseReceptor revision; Peripheral T cell toleranc
Osteopontin is critical to determine symptom severity of influenza through the regulation of NK cell population
Keywords: Tg، ترانس ژنیک; IAV, influenza A virus; OPN, osteopontin; rOPN, recombinant osteopontin; TNF-α, tumor necrosis factor-α; IL, interleukin; IFN, interferon; Con-A, concanavalin A; KO, knockout; Tg, transgenic; NK cells, natural killer cells; WT, wild type; DAB, 3,3′-diamin
Therapeutic chaperone effect of N-Octyl 4-Epi-β-valienamine on murine GM1-gangliosidosis
Keywords: Tg، ترانس ژنیک; β-gal, β-galactosidase; NOEV, N-octyl 4-epi-β-valienamine; DGJ, 1-deoxygalactonojirimycin; WT, wild type; KO, knockout; Tg, transgenic; LC, liquid chromatography; MS/MS, tandem mass spectrometry; LLOQ, lower limit of quantification; GOT, glutamic-oxalacet
Regulation of microRNA expression in the heart by the ATF6 branch of the ER stress response
Keywords: Tg، ترانس ژنیک; ATF6, activation of transcription factor 6; Calr, calreticulin; miRNA, microRNA; UPR, unfolded protein response; MER, mutant mouse estrogen receptor; MER-ATF6, fusion protein with the MER fused to the C-terminal of ATF6; TG, transgenic; NTG, non-transgeni
Transgenic overexpression of USP15 in the heart induces cardiac remodeling in mice
Keywords: Tg، ترانس ژنیک; USP15, ubiquitin-specific protease 15; SLIM1, skeletal muscle LIM protein 1; TG, transgenic; WT, wild-type; Ub, ubiquitin; HW/BW, heart weight to body weight; ANP, atrial natriuretic peptide; BNP, B-type natriuretic peptide; MHC, myosin heavy chainDeubiqu
Expansion of regulatory T cells in aged mice following influenza infection
Keywords: Tg، ترانس ژنیک; HAU, hemagglutination unit; LCMV, lymphocytic choriomeningitis virus; Tg, transgenic; NP, NP366–374/Db; HA, HA518–526/Kd; GP, GP33–41/DbRegulatory T cells; Aging and influenza
Transgenic expression of bovine neonatal Fc receptor in mice boosts immune response and improves hybridoma production efficiency without any sign of autoimmunity
Keywords: Tg، ترانس ژنیک; FcRn, neonatal Fc receptor; IgG, immunoglobulin G; BSA, bovine serum albumin; OVA, ovalbumin; KLH, keyhole limpet haemocyanin; wt, wild type; Tg, transgenic; MC, microculture; mAb, monoclonal antibody; dsDNA, double stranded DNA; ssDNA, single stranded DN
Myosin cross-bridges do not form precise rigor bonds in hypertrophic heart muscle carrying troponin t mutations
Keywords: Tg، ترانس ژنیک; EDC, 1-ethyl-3-[3-(dimethylamino)propyl]carbodiimide; Tg, Transgenic; NTg, Non Transgenic; WT, Wild Type; MUT, Mutated; S, Skewness of distribution; K, Kurtosis of distribution; SD, Standard Deviation; FHC, Familial Hypertrophic Cardiomyopathy; TnT, Tropo
NF-κB in the mechanism of brain edema in acute liver failure: Studies in transgenic mice
Keywords: Tg، ترانس ژنیک; ALF, acute liver failure; ALT, alanine aminotransferase; AST, aspartate aminotransferase; iNOS, nitric oxide synthase; MAPKs, mitogen-activated protein kinases; NF-κB, nuclear factor-κB; NOX, NADPH oxidase; TAA, thioacetamide; Tg, transgenic; WT, wild typ
Of mice and not humans: How reliable are animal models for evaluation of herpes CD8+-T cell-epitopes-based immunotherapeutic vaccine candidates?
Keywords: Tg، ترانس ژنیک; HLA, Human Leukocyte Antigen; HSV, herpes simplex virus; IFN-γ, interferon gamma; Tg, transgenic; TG, trigeminal gangliaTherapeutic vaccine; Animal model; HSV-1; HSV-2; Ocular herpes; Genital herpes; CD8+ T cells
Alteration of Methamphetamine-induced stereotypic behaviour in transgenic mice expressing HIV-1 envelope protein gp120
Keywords: Tg، ترانس ژنیک; HIV, human immunodeficiency virus; HAND, HIV-associated neurological disorders; HAD, HIV-associated dementia; tg, transgenic; SCID, severe combined immunodeficiency; AIDS, acquired immunodeficiency syndromeMethamphetamine; HIV; Envelope protein; Behaviour
Enhancement of virus-specific expansion of transgenic CD8 T cells in aged mice by dendritic cells
Keywords: Tg، ترانس ژنیک; DC, dendritic cell; HAU, hemagglutination unit; Tg, transgenic; HA, hemagglutininT cells; Viral; Dendritic cells; Aging
The TCR-mediated signaling pathways that control the direction of helper T cell differentiation
Keywords: Tg، ترانس ژنیک; APC, antigen presenting cells; dnCN, dominant-negative calcineurin; dnRas, dominant-negative Ras; TCR, T cell receptor; Th, helper T; Tg, transgenic; Treg, T regulatoryTh1; Th2; Th17; iTreg; TCR signaling; Functional differentiation
Transgenic mice overexpressing methionine sulfoxide reductase A: Characterization of embryonic fibroblasts
Keywords: Tg، ترانس ژنیک; DMEM, Dulbecco's modified Eagle's medium; MetO, methionine sulfoxide; Msr, methionie sulfoxide reductase; MEF, mouse embryonic fibroblast; ROS, reactive oxygen species; Tg, transgenic; TgCyto, transgenic targeted to the cytosol; TgMito, transgenic targete
Positive selection of T cells, an in vitro view
Keywords: Tg، ترانس ژنیک; HSC, hematopoietic stem cell; Dll, delta-like; DN, double negative; DP, double positive; FTOC, fetal thymic organ culture; pMHC, self-peptide/MHC; RTOC, reaggregate thymic organ culture; SP, single positive; TEC, thymic epithelial cell; Tg, transgenic; TN
Inhibition of hepatic damage and liver fibrosis by brain natriuretic peptide
Keywords: Tg، ترانس ژنیک; BNP, brain natriuretic peptide; CCl4, carbon tetrachloride; Tg, transgenic; WT, wild-type; TGF, transforming growth factor; Col1a1, type I procollagen α1 chain; HSC(s), hepatic stellate cell(s) NP, natriuretic peptide; ANP, atrial natriuretic peptide; CNP
Characterization of hepatic sexual dimorphism in Alb-DsRed2 transgenic rats
Keywords: Tg، ترانس ژنیک; GH, Growth hormone; Tg, transgenic; IVIS, in vivo bio-imaging system; Hypox, hypophysectomy; STAT, signal transducer and activator of transcriptionSexual dimorphism; Pituitary hormone; Hepatocytes; Transgenic rat
Unusual circadian locomotor activity and pathophysiology in mutant CRY1 transgenic mice
Keywords: Tg، ترانس ژنیک; Tg, transgenic; CRY, cryptochrome; DD, constant darkness; LD, light dark; LL, constant light; SCN, suprachiasmatic nucleusBiological rhythm; Cryptochrome; Transgenic mice; Circadian clock; Rhythm splitting; Diabetes mellitus
Functions of oligochitosan induced protein kinase in tobacco mosaic virus resistance and pathogenesis related proteins in tobacco
Keywords: Tg، ترانس ژنیک; Oligochitosan induced protein kinase; Transgenic tobacco; TMV resistance; Pathogenesis related proteinsOC, Oligochitosan; TG, transgenic; OIPK, oligochitosan induced protein kinase; TMV, tobacco mosaic virus; WT, wild type; PR, pathogenesis related; PAL,
Regulatory light chain mutations associated with cardiomyopathy affect myosin mechanics and kinetics
Keywords: Tg، ترانس ژنیک; FHC, Familial hypertrophic cardiomyopathy; RLC, Regulatory light chain; MHC, Myosin heavy chain; Tg, Transgenic; NTg, Non-transgenic.Motility assay; ATPase; RLC; Optical trapping; FHC; Calcium binding site
Limited expansion of virus-specific CD8 T cells in the aged environment
Keywords: Tg، ترانس ژنیک; HAU, hemagglutination unit; LCMV, lymphocytic choriomeningitis virus; DC, dendritic cell; Tg, transgenic; NP, NP366–374/Db; HA, HA518–526/Kd; GP, GP33–41/DbT cells; Viral; Dendritic cells; Transgenic mice; Aging
Amelioration of Colitis by Genetically Engineered Murine Regulatory T Cells Redirected by Antigen-Specific Chimeric Receptor
Keywords: Tg، ترانس ژنیک; CR, chimeric receptor; Teff, effector T cells; Tg, transgenic; nTregs, naturally occurring regulatory T cells; TNBS, 2,4,6-trinitrobenzenesulphonic acid; TNP, 2,4,6-trinitrophenol; TPCR, tripartite chimeric receptor; Tregs, regulatory T cells
Targeted Epithelial Tight Junction Dysfunction Causes Immune Activation and Contributes to Development of Experimental Colitis
Keywords: Tg، ترانس ژنیک; CA-MLCK, constitutively active myosin light chain kinase; MLC, myosin II regulatory light chain; MLCK, myosin light chain kinase; PIK, membrane Permeant Inhibitor of myosin light chain Kinase; Tg, transgenic; WT, wild-type
The Role of the N-Terminus of the Myosin Essential Light Chain in Cardiac Muscle Contraction
Keywords: Tg، ترانس ژنیک; ELC, essential light chain; Tg, transgenic; Tg-WT, human ventricular ELC wild type; Tg-Δ43, 43-amino-acid N-terminal truncation mutant; MHC, myosin heavy chain; MLC, myosin light chain; RLC, regulatory light chain; huELCv, human ventricular ELC; FHC, fami
Regulation of the roles of sphingosine 1-phosphate and its type 1 G protein-coupled receptor in T cell immunity and autoimmunity
Keywords: Tg، ترانس ژنیک; S, sphingosine; S1P, sphingosine 1-phosphate; GPCR, G protein-coupled receptor; S1P1, type 1 GPCR for S1P; TG, transgenic; WT, wild-type; TCR, T cell antigen receptor; OVA, a distinct substituent peptide epitope of ovalbumin; OTII, a line of C57BL/6 mice
In vivo bioimaging using photogenic rats: Fate of injected bone marrow-derived mesenchymal stromal cells
Keywords: Tg، ترانس ژنیک; Transgenic rat; Luciferase; Luminescent imaging; Chemokine receptorsGFP, green fluorescent protein; Luc, luciferase; Tg, transgenic; LEW, Lewis; LacZ, beta-galactosidase; MHC, major histocompatibility complex; HSC, hematopoietic stem cell; MSC, mesenchyma
Selective loss of nigral dopamine neurons induced by overexpression of truncated human α-synuclein in mice
Keywords: Tg، ترانس ژنیک; DA, dopamine; H&E, hematoxylin and eosin; LB, Lewy body; PD, Parkinson's disease; SNc, substantia nigra pars compacta; Tg, transgenic; TH, tyrosine hydroxylase; VTA, ventral tegmental areaParkinson's disease; Animal model; α-Synuclein; Transgenic mouse; T
Clinical implications from studies of α1 adrenergic receptor knockout mice
Keywords: Tg، ترانس ژنیک; α1-ARs, α1-adrenergic receptors; KO, knockout; TG, transgenic; LUT, lower urinary tract; CNS, central nervous system; BPH, benign prostatic hypertrophy; WT, wild-typeα1-Adrenergic receptors; Knockout mice; Lower urinary tract; Central nervous system; Drug
Possible enhancing activity of diacylglycerol on 4-nitroquinoline 1-oxide induced carcinogenesis of the tongue in human c-Ha-ras proto-oncogene transgenic rats
Keywords: Tg، ترانس ژنیک; DAG, diacylglycerol; 4NQO, 4-nitroquinoline 1-oxide; Tg, transgenic; TAG, triacylglycerol; SCC, squamous cell carcinomas; PKC, protein kinase C; TG, triglycerides; FFA, free fatty acids; T-Cho, total cholesterol; LP, lipoprotein; GOT, glutamic oxaloacetic
Infarct volume after transient middle cerebral artery occlusion (MCAo) can be reduced by attenuation but not by inactivation of c-Jun action
Keywords: Tg، ترانس ژنیک; AP-1, activator protein-1; ATF, activating transcription factor; JNK, Jun N-terminal kinase; MCA(o), middle cerebral artery (occlusion); SAPK, stress-activated protein kinase; tg, transgenic; TRAIL, tumor necrosis factor-related apoptosis-inducing ligand
Insulin-like growth factor-I (IGF-I) inhibits neuronal apoptosis in the developing cerebral cortex in vivo
Keywords: Tg، ترانس ژنیک; ANOVA, analysis of variance; NA, areal density (cells/mm2); E, embryonic day; IGF-I, insulin-like growth factor-I; i.p., intraperitoneal; NV, numerical density (cells/mm3); P, postnatal day; SVZ, subventricular zone; Tg, transgenic; VZ, ventricular zoneAp
Up-regulation of Bcl-2 in APP transgenic mice is associated with neuroprotection
Keywords: Tg، ترانس ژنیک; Tg, Transgenic; NTg, nontransgenic; AD, Alzheimer's disease; Bcl-2, B-cell CLL/lymphoma 2; APP, amyloid precursor protein; PS1, presenilin 1Bax; APP + PS1 transgenic mice; Alzheimer's disease; Neurotoxicity; Aβ; Apoptosis
Association of the pre-B cell receptor (BCR) expression level with the quality of pre-BII cell differentiation reveals hierarchical pre-BCR function
Keywords: Tg، ترانس ژنیک; BCR, B cell receptor; Tg, transgenic; SLC, surrogate light chain; CDR3, third complementarity determining region; MZ, marginal zone; HK1, hemokinin 1IL-7; Hemokinin 1; VH12; Positive selection
Structural and functional analysis of the sarcoglycan–sarcospan subcomplex
Keywords: Tg، ترانس ژنیک; DG, dystroglycan; DGC, dystrophin–glycoprotein complex; LEL, large extracellular loop; SEL, small extracellular loop; SIL, small intracellular loop; SSPN, sarcospan; SG, sarcoglycan; TG, transgenic; TM, transmembrane domainSarcospan; Sarcoglycan; Dystroph
The corticostriatal pathway in Huntington's disease
Keywords: Tg، ترانس ژنیک; HD, Huntington's disease; CAG, (cytosine adenine guanine) DNA triplet sequence coding for glutamine; YAC, yeast artificial chromosome; Tg, transgenic; MSSN, medium-sized spiny neuron; NMDA, N-methyl-d-aspartate; AMPA, α-amino-3-hydroxy-5-methyl-4-isoxazol