Excretion of Δ9-tetrahydrocannabinol in sweat
Keywords: THC; Sweat; Excretion; GC/MS; Cannabinoid; Marijuana
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Assessment of forebrain-dependent trace eyeblink conditioning in chronic cannabis users
Keywords: Trace eyeblink conditioning; Cannabis; CB1 receptor; THC; Hippocampus; Associative learning; N100
Simultaneous analysis of THC and its metabolites in blood using liquid chromatography–tandem mass spectrometry
Keywords: THC; Blood; LLE; LC–MS/MS
Perinatal delta-9-tetrahydrocannabinol exposure disrupts social and open field behavior in adult male rats
Keywords: THC; Marijuana; Prenatal; Perinatal; Social behavior; Anxiety; Forced swim test; Cannabinoid
Chemical stability and bioadhesive properties of an ester prodrug of Δ9-tetrahydrocannabinol in poly(ethylene oxide) matrices: Effect of formulation additives
Keywords: Bioadhesion; THC; Poly(ethylene oxide); Stability; Prodrug; Antioxidants
Neural Basis of Δ-9-Tetrahydrocannabinol and Cannabidiol: Effects During Response Inhibition
Keywords: CBD; THC; fMRI; hippocampus; inferior frontal gyrus; response inhibition
Evaluation of fatty acid amides in the carrageenan-induced paw edema model
Keywords: Endogenous cannabinoid; Fatty acid amide hydrolase (FAAH); Inflammation; THC; N-Arachidonoyl ethanolamine (anandamide); N-Palmitoyl ethanolamine (PEA); Edema;
CB1 receptor stimulation in specific brain areas differently modulate anxiety-related behaviour
Keywords: THC; Anxiety behaviour; Prefrontal cortex; Hippocampus; Amygdala; CREB activation;
Influence of plasticizers on the stability and release of a prodrug of Δ9-tetrahydrocannabinol incorporated in poly (ethylene oxide) matrices
Keywords: THC; Plasticizers; Stability; Hot-melt; Poly (ethylene oxide); Release; Microenvironmental pH; Prodrug
Cross-sensitization and cross-tolerance between exogenous cannabinoid antinociception and endocannabinoid-mediated stress-induced analgesia
Keywords: Endocannabinoid; Sensitization; Stress antinociception; Rimonabant; Tolerance; Footshock; Anxiety; THC;
Urine Drug Screening: Practical Guide for Clinicians
Keywords: 6-MAM; monoacetylmorphine; BAC; blood alcohol concentration; DHHS; Department of Health and Human Services; EMIT; enzyme-multiplied immunoassay technique; FPIA; fluorescence polarization immunoassay; GC-MS; gas chromatography-mass spectrometry; MDMA; meth
A single low dose of tetrahydrocannabinol induces long-term cognitive deficits
Keywords: Tetrahydrocannabinol; THC; Cannabinoid; Neurotoxicity; Morris water maze
Cannabinoid CB1 receptor inverse agonists and neutral antagonists: Effects on food intake, food-reinforced behavior and food aversions
Keywords: Appetite; Motivation; Operant; Feeding; THC; Rimonabant
Confirmation of cannabinoids in meconium using two-dimensional gas chromatography with mass spectrometry detection
Keywords: Cannabinoids; THC; Meconium; Two-dimensional GC; Mass spectrometry; Deans switch
Oral delta-9-tetrahydrocannabinol suppresses cannabis withdrawal symptoms
Keywords: Cannabis; Marijuana; Withdrawal; THC; Dronabinol
Dorsolateral Prefrontal Cortex N-Acetylaspartate/Total Creatine (NAA/tCr) Loss in Male Recreational Cannabis Users
Keywords: Cannabidiol; cannabis; DLPFC; MRSI; neuropsychological; THC
Differential responses to cannabis potency: A typology of users based on self-reported consumption behaviour
Keywords: Cannabis; THC; Consumption patterns; Cluster analysis; Typology
Heterozygous neuregulin 1 mice display greater baseline and Î9-tetrahydrocannabinol-induced c-Fos expression
Keywords: cannabinoid; c-Fos; schizophrenia; susceptibility gene; transgenic mice; ANOVA; analysis of variance; BNST; bed nucleus of the stria terminalis; CEA; central nucleus of the amygdala; CPU; caudate putamen; LH; lateral hypothalamus; LSV; ventrolateral septu
Chronic use of marijuana decreases cannabinoid receptor binding and mRNA expression in the human brain
Keywords: Cannabis sativa; CB1 receptor binding; chronic drug exposure; postmortem human brain; mRNA CB1 expression; psychostimulants; Bmax; maximal capacity; CA1, CA2, CA3, CA4; areas of Ammon's horn; CB1, CB2; cannabinoid receptors; cDNA; complementary DNA; cRN
Nonreporting of cannabis use: Predictors and relationship to treatment outcome in methadone maintained patients
Keywords: Cocaine; Heroin; Marijuana; THC; Substance Use; Self-Report
Marijuana use, adolescent pregnancy, and alteration in newborn behavior: How complex can it get?
Keywords: Î8-THC; Î8-tetrahydrocannabinol; NNNS; Neonatal Intensive Care Unit Network Neurobehavioral Scale; THC; Î9-tetrahydrocannabinol;
Determination of cannabinoids in biological samples using a new solid phase micro-extraction membrane and liquid chromatography–mass spectrometry
Keywords: Solid phase micro-extraction membrane (SPMEM); THC; CBD; LC–MS
Correlation of Δ9-tetrahydrocannabinol concentrations determined by LC–MS–MS in oral fluid and plasma from impaired drivers and evaluation of the on-site Dräger DrugTest®
Keywords: Oral fluid; Plasma; THC; Driving under the influence; Roadside drug test
Delta-9-tetrahydrocannabinol and cannabidiol, but not ondansetron, interfere with conditioned retching reactions elicited by a lithium-paired context in Suncus murinus: An animal model of anticipatory nausea and vomiting
Keywords: Chemotherapy; Nausea; Emesis; Cannabinoids; Cannabidiol; THC; Marijuana; Ondansetron; Serotonin; Classical conditioning; Shrew; Learning
Differential effects of cannabis extracts and pure plant cannabinoids on hippocampal neurones and glia
Keywords: Cannabinoids; THC; CBD; Calcium; Cell culture
The effect of Δ9-tetrahydrocannabinol on sensorimotor gating in socially isolated rats
Keywords: Cannabinoid; Prepulse inhibition; Social isolation; Schizophrenia; THC; SR 141716
Disturbances of visual information processing in early states of psychosis and experimental delta-9-tetrahydrocannabinol altered states of consciousness
Keywords: Cannabis; Visual perception; Binocular depth inversion; Dronabinol; THC; Schizophrenia; Prodromal states
Effects of infection of EGFP-expressing Escherichia coli on haemocytes in Ciona intestinalis
Keywords: EGFP; enhanced green fluorescence protein; TUNEL; terminal-deoxynucleotidyl transferase mediated nick end labeling; THC; total haemocytes count; SCGE; single cell gel electrophoresis; Apoptosis; Cellular response; Ciona intestinalis; EGFP-expressing E. co
Influence of the anabolic-androgenic steroid nandrolone on cannabinoid dependence
Keywords: Anabolic-androgenic steroid; Nandrolone; THC; Dependence; Anxiety; Mice
Long-term effects of exposure to cannabis
Keywords: THC; Î9-tetrahydrocannabinol;
Effect of Î9-tetrahydrocannabinol on sucrose palatability as measured by the taste reactivity test
Keywords: Cannabinoid; Feeding; Liking; Taste reactivity; THC; Sucrose; Rat;
Reactive oxygen species and p38 phosphorylation regulate the protective effect of Î9-tetrahydrocannabinol in the apoptotic response to NMDA
Keywords: THC; NMDA; Reactive oxygen species; Apoptosis; MAP kinase; Neuroprotection;
Effects of repeated administration with CP-55,940, a cannabinoid CB1 receptor agonist on the metabolism of the hepatic heme
Keywords: ALA-S; aminolevulinate synthase; CYPs; cytochrome P-450s; GSH; gluthation; HO; heme oxygenase; PBG-D; porphobilinogen deaminase; THC; Î9-tetrahydrocannabinol; UROD; uroporphyrinogen decarboxylase; Cannabinoid CB1 receptor agonist CP-55,940; Hepatic porph
Acute Î9-tetrahydrocannabinol exposure facilitates quinpirole-induced hyperlocomotion
Keywords: Behavior; Cannabinoids; CB1 receptors; Dopamine receptors; Locomotion; Quinpirole; THC; Sensitization;
CB1 receptor knockout mice show similar behavioral modifications to wild-type mice when enkephalin catabolism is inhibited
Keywords: CMS; chronic unpredictable mild stress; FAAH; fatty acid amide hydrolase; RB101; {N-[(R,S)-2-benzyl-3[(S)(2-amino-4-methyl-thio)-butyldithio]-1-oxo-propyl]-l-phenyl-alanine benzyl ester}; THC; delta-9-tetrahydrocannabinol; Neural basis of behavior; Neurop
Novel time-dependent vascular actions of Î9-tetrahydrocannabinol mediated by peroxisome proliferator-activated receptor gamma
Keywords: THC; PPARγ; Endothelium; Aorta; Superior mesenteric artery; Vasorelaxation; Cannabinoid; Nitric oxide; SOD;
Sex differences in behavioral effects of cannabinoids
Keywords: Gender; THC; Marijuana; Females
Î9-tetrahydrocannabinol increases C6 glioma cell death produced by oxidative stress
Keywords: CB1 receptor; quinone; ESR; ROS; glucose starvation; glucose uptake; CHO; Chinese hamster ovary; DMPO; 5â²,5â²-dimethyl-1-pyroline N-oxide; ESR; electron spin resonance; LDH; lactate dehydrogenase; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazol
Paraventricular hypothalamic CB1 cannabinoid receptors are involved in the feeding stimulatory effects of Î9-tetrahydrocannabinol
Keywords: Cannabinoids; Tetrahydrocannabinol; THC; Feeding behaviour; PVN; Rats; SR 141716;
Chronic Î9-tetrahydrocannabinol treatment produces antinociceptive tolerance in mice without altering Protein Kinase A activity in mouse brain and spinal cord
Keywords: Cannabinoid; THC; Antinociception; Tolerance; Protein Kinase A;
Increased gabaergic input to ventral tegmental area dopaminergic neurons associated with decreased cocaine reinforcement in μ-opioid receptor knockout mice
Keywords: opioids; addiction; ventral tegmental area; GABA; dopamine; cocaine; aCSF; artificial cerebrospinal fluid; CPP; conditioned place preference; DAMGO; [d-Ala, Nme-Phe, Gly-ol]-enkephalin; mIPSC; miniature inhibitory post-synaptic current; MOR; μ-opioid rec
Unifying mechanism for toxicity and addiction by abused drugs: electron transfer and reactive oxygen species
Keywords: ET; electron transfer; OS; oxidative stress; ROS; reactive oxygen species; SO; superoxide; CNS; central nervous system; AO; antioxidant; SOD; superoxide dismutase; GSH; glutathione; MA; methamphetamine; MAO; monoamine oxidase; MDMA; methylenedioxymethamph
Stimulatory Effects of Testosterone and Progesterone on the NADH-and NADPH-dependent Oxidation of 7β-Hydroxy-Î8-tetrahydrocannabinol to 7-Oxo-Î8-tetrahydrocannabinol in Monkey Liver Microsomes
Keywords: tetrahydrocannabinol; testosterone; cytochrome P450; microsomal alcohol oxygenase; monkey; liver; THC; tetrahydrocannabinol; CYP; cytochrome P450; MALCO; microsomal alcohol oxygenase; a-NF; a-naphthoflavone; GC; gas chromatography; MS; mass spectrometry;
Quantitative analysis of Î9-tetrahydrocannabinol in preserved oral fluid by liquid chromatography-tandem mass spectrometry
Keywords: LC-MS-MS; Oral fluid; THC;
Evidence for novel cannabinoid receptors
Keywords: Endocannabinoids; Cannabinoid receptors; Endothelium; Vasodilation; Hippocampus; 2-AG; 2-arachidonoylglycerol; abn-cbd; abnormal cannabidiol; BKCa; large conductance calcium-activated potassium channel; CGRP; calcitonin gene-related peptide; DSI or DSE; d
Antifibrogenic role of the cannabinoid receptor CB2 in the liver
Keywords: AC-DEVD-AFC; N-acetyl-Asp-Glu-Val-Asp-7-amino-4-trifluoromethyl coumarin; APAAP; alkaline phosphatase-anti-alkaline phosphatase; COX-2; cyclooxygenase-2; DCFH-DA; 2â²,7â²-dichlorofluorescein diacetate; hMF; hepatic myofibroblasts; NAC; N-acetyl-cysteine
Self-administration of cannabinoids by experimental animals and human marijuana smokers
Keywords: Cannabis; Cannabinoids; Delta-9-tetrahydrocannabinol; Humans; Marijuana; Squirrel monkeys; Primates; Reinforcement; Reward; Rodents; Self-administration; THC;
Differential Expression of Cannabinoid Receptors in the Human Colon: Cannabinoids Promote Epithelial Wound Healing
Keywords: AEA; anandamide; DNBS; dinitrobenzene sulphonic acid; ERK; extracellular-regulated kinase; FAAH; fatty acid amide hydrolase; GSK; glycogen synthase kinase; LPA; lysophosphatidic acid; MAPK; mitogen-activated protein kinase; NE; noladin ether; PI3K; phosph
Contribution of natural products to the discovery of the transient receptor potential (TRP) channels family and their functions
Keywords: Natural products; Capsaicin; Resiniferatoxin; TRPV1; TRPM8; TRPA1; ANKTM; ankyrin-like protein with transmembrane; ATP; adenosine triphosphate; Ca2+; calcium; cDNA; complementary deoxyribonucleic acid; CGRP; calcitonin gene-related peptide; CHO cells; Chi