Keywords: تیوفلاین-T; Amino acid sensor; Thioflavin-T; Molecular rotor; Fluorescence sensor; H-aggregate; Ratiometry; Arginine and lysine;
مقالات ISI تیوفلاین-T (ترجمه نشده)
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Keywords: تیوفلاین-T; IAPP; islet amyloid polypeptide; hIAPP; human IAPP; DEPC; diethylpyrocarbonate; DMI; DEPC-modified hIAPP; HFIP; 1,1,1,3,3,3-hexafluoro-2-propanol; ThT; thioflavin-T; Modification; Amyloid; hIAPP; Imidazole ring;
Keywords: تیوفلاین-T; Septin; Protein-protein interaction; Protein-lipid interaction; GTP binding protein; CD; Circular dichroism; CSM; Center of spectral mass; DOPC; 1,2-Dioleoyl-sn-glycero-3-phosphocholine; GUV; Giant unilamelar vesicle; ITC; Isothermal titration calorimetry
Keywords: تیوفلاین-T; Amyloid; Protein aggregation inhibitors; Inclusion bodies; ProteoStat; Screening; Aβ; β-amyloid peptide; AD; Alzheimer's disease; APF; aggregation propensity factor; APP; amyloid precursor protein; CR; Congo Red; DMSO; dimethyl sulfoxide; FC; flow cytom
Keywords: تیوفلاین-T; Variable domain of heavy-chain antibody; Inhibition of protein misfolding and aggregation; Protein misfolding diseases; Amyloidoses; VHH; Nanobody; Ab; antibody; Aβ; amyloid β-peptide; AD; Alzheimer's disease; ANS; anilino naphthalene-sulfonic acid; AP;
Keywords: تیوفلاین-T; AFM; atomic force microscopy; AGE; advanced glycated end product; BSA; bovine serum albumin; IncBSA; bovine serum albumin incubated at 37°C; MES; 2-(N-morpholino) ethane sulfonic acid; PAGE; polyacrylamide gel electrophoresis; PBS; phosphate buffered sal
Keywords: تیوفلاین-T; DOI; desoctapeptide-(B23-B30) insulin; RP-HPLC; reversed phase high performance liquid chromatography; CD; circular dichroism; ThT; thioflavin-T; TEM; transmission electron-microscopy; POPG; 2-oleoyl-1-palmitoyl-sn-glycerol-3-phospho-rac(1-glycerol) sod
Keywords: تیوفلاین-T; AD; Alzheimer's disease; ANS; 1-anilinonaphthalene-8-sulfonic acid; AS; α-synuclein; CMC; critical micellar concentration; CTE; chronic traumatic encephalopathy; EPR; electron paramagnetic; ETeff; energy transfer efficiency; FRET; Förster resonance en
Concerted action of dipeptidyl peptidase IV and glutaminyl cyclase results in formation of pyroglutamate-modified amyloid peptides in vitro
Keywords: تیوفلاین-T; Amyloid beta peptides; Dipeptidyl peptidase IV; Enzyme-substrate interactions; Glutaminyl cyclase; MALDI-TOF mass spectrometry; Aβ; amyloid beta peptide; Aβ(1-40); amyloid beta peptide (1-40); Aβ(1-42); amyloid beta peptide (1-42); AD; Alzheimer's dise
Mechanistic analyses of the suppression of amyloid β42 aggregation by apomorphine
Keywords: تیوفلاین-T; Aβ; amyloid β-protein; AD; Alzheimer's disease; HFIP; 1,1,1,3,3,3,-hexafluoroisopropyl alcohol; HMQC; heteronuclear multiple quantum coherence; HPLC; high performance liquid chromatography; LC-MS; liquid chromatography-mass spectrometry; LC/Q Tof-MS
C-terminal truncation exacerbates the aggregation and cytotoxicity of α-Synuclein: A vicious cycle in Parkinson's disease
Keywords: تیوفلاین-T; α-Syn; alpha-synuclein; α-Syn FL; full-length alpha-synuclein; α-Syn121; C-terminal truncated alpha-synuclein 1-121; C19; C-terminal 19-residues peptide of alpha-synuclein; CD; circular dichroism; DLB; dementia with Lewy bodies; DLS; dynamic light scat
Inhibition of Alzheimer's amyloid-beta aggregation in-vitro by carbenoxolone: Insight into mechanism of action
Keywords: تیوفلاین-T; Alzheimer's disease; Amyloid-beta 42; Carbenoxolone; Oligomers; Fibrils; Anti-fibrillation; AD; Alzheimer's disease; Aβ; Amyloid beta; Cbx; carbenoxolone; APP; Amyloid precursor protein; Th-T; Thioflavin-T; CD; Circular dichroism; SVAU; Sedimentation vel
In vitro monitoring of amyloid β-peptide oligomerization by Electrospray differential mobility analysis: An alternative tool to evaluate Alzheimer's disease drug candidates
Keywords: تیوفلاین-T; Aβ; Amyloid-beta peptide; AD; Alzheimer's disease; CE; Capillary Electrophoresis; ThT; Thioflavin-T; TEM; Transmission Electron Microscopy; DC; drug candidate; SEC; Size Exclusion Chromatography; FCS; fluorescence correlation spectroscopy; FFF; field flo
Overcoming electrostatic repulsions during amyloid assembly: Effect of pH and interaction with divalent metals using model peptides
Keywords: تیوفلاین-T; Amyloid; Peptides; Electrostatic repulsion; pH; Divalent metals; Coordination; Th-T; Thioflavin-T; Mg+2; magnesium ion; Mn+2; manganese ion; K+; potassium ion; TEM; transmission electron microscopy; NTases; nucleotydil transferases;
Detection of amyloid-β fibrils using the DNA-intercalating dye YOYO-1: Binding mode and fibril formation kinetics
Keywords: تیوفلاین-T; YOYO-1; Thioflavin-T; Amyloid fibril; Amyloid-β; Fluorescence; Linear dichroism;
Steady-state and time-resolved Thioflavin-T fluorescence can report on morphological differences in amyloid fibrils formed by Aβ(1-40) and Aβ(1-42)
Keywords: تیوفلاین-T; Amyloid-β; Amyloid fibrils; Alzheimer's disease; Thioflavin-T; Amyloid dye; Fluorescence lifetime;
Ultrafast torsional dynamics of Thioflavin-T in an anionic cyclodextrin cavity
Keywords: تیوفلاین-T; Thioflavin-T; Sulphobutylether β-cyclodextrin; Ultrafast torsional dynamics; Fluorescence; Confinement
Ginsenoside Rb1 inhibits fibrillation and toxicity of alpha-synuclein and disaggregates preformed fibrils
Keywords: تیوفلاین-T; α-syn; α-synuclein; PD; Parkinson's disease; Aβ; beta amyloid; LBs; Lewy bodies; LNs; Lewy neuritis; Gn; ginsenoside; GST; glutathione S-transferase; IPTG; isopropyl β-d-1-thiogalactopyranoside; DTT; dithiothreitol; SDS; sodium dodecyl sulfate; PBS; p
Pitfalls associated with the use of Thioflavin-T to monitor anti-fibrillogenic activity
Keywords: تیوفلاین-T; α-Synuclein; Fibrils; Thioflavin-T; NMR; Dopamine; DOPAL;
Solution conditions define morphological homogeneity of α-synuclein fibrils
Keywords: تیوفلاین-T; αSyn; α-synuclein; AFM; Atomic Force Microscopy; A140C αSyn; substitution mutant of αSyn with residue 140 mutated from alanine to cysteine; EDTA; ethylenediaminetetraacetic acid; TCEP; tris(2-carboxyethyl)phosphine hydrochloride; DTT; dithiothreitol;
Toward a common aggregation mechanism for a β-barrel protein family: Insights derived from a stable dimeric species
Keywords: تیوفلاین-T; IFABP; intestinal fatty acid binding protein; Î98Î; a truncated variant of IFABP corresponding to the fragment 29-126 of the parent protein; Î78Î; a truncated variant of IFABP corresponding to the fragment 29-106 of the parent protein; TFE; 2,2,2-
Active and peripheral anionic sites of acetylcholinesterase have differential modulation effects on cell proliferation, adhesion and neuritogenesis in the NG108-15 cell line
Keywords: تیوفلاین-T; Acetylcholinesterase; Peripheral anionic site; Acylation site; Cell adhesion; Proliferation; Neuritogenesis; ACh; acetylcholine; AChE; acetylcholinesterase; BSA; bovine serum albumin; ChE; cholinesterase; CV; crystal violet; dbcAMP; (dybutyryl cyclic-AMP)
Gadolinium-based contrast agents targeted to amyloid aggregates for the early diagnosis of Alzheimer's disease by MRI
Keywords: تیوفلاین-T; Alzheimer's disease; Amyloid; Gadolinium; DOTA; Pyridine containing TriAza (PCTA); Magnetic resonance imaging (MRI); BAT; bis-amine-bis-thiol; BTA; 2-(4-N-methylaminophenyl)benzothiazole; CA; contrast agent; CMC; critic micelle concentration; CV; cone vol
Molecular and cytotoxic properties of hIAPP17-29 and rIAPP17-29 fragments: A comparative study with the respective full-length parent polypeptides
Keywords: تیوفلاین-T; Spectroscopy; Type 2 diabetes; Confocal microscopy; Mitochondria; Amyloid; Model membranes; hIAPP; human islet amyloid polypeptide; IAPP; islet amyloid polypeptide; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; rIAPP; rodent islet amy
Proanthocyanidins are the major anti-diabetic components of cinnamon water extract
Keywords: تیوفلاین-T; CD; circular dichroism; CWE; cinnamon water extract; EGCG; (â)-epigallocatechin 3-gallate; HFIP; hexafluoroisopropanol; hIAPP; human islet amyloid polypeptide; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; PA; proanthocyanidins; PBS
In silico and in vitro characterization of anti-amyloidogenic activity of vitamin K3 analogues for Alzheimer's disease
Keywords: تیوفلاین-T; Aβ; amyloid-beta; VK; vitamin K; AD; Alzheimer's disease; IC50; half maximal inhibitory concentration; ApoE; apolipoprotein E; MD; molecular dynamics; MM-PBSA; molecular mechanics-PoissonâBoltzmann surface area; SI; supplemental information; DCFH-DA; d
Silibinin inhibits the toxic aggregation of human islet amyloid polypeptide
Keywords: تیوفلاین-T; CD; circular dichroism; EGCG; (â)-epigallocatechin 3-gallate; HFIP; hexafluoroisopropanol; hIAPP; human islet amyloid polypeptide; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; T2DM; type 2 diabetes mellitus; TEM; transmission elect
Dissecting the role of disulfide bonds on the amyloid formation of insulin
Keywords: تیوفلاین-T; Insulin; Diabetes; Disulfide bonds; Fibrillation; Oligomerization; Hemolysis; TCEP; Tris(2-carboxyethyl)phosphine; CD; circular dichroism; TEM; transmission electron-microscopy; ThT; Thioflavin-T; PICUP; photo-induced cross-linking of unmodified proteins;
Ultrafast torsional dynamics in nanoconfined water pool: Comparison between neutral and charged reverse micelles
Keywords: تیوفلاین-T; Reverse micelles; Bond twisting; Fluorescence; Time-resolved spectroscopy; Thioflavin-T
Effects of intravenous immunoglobulin on alpha synuclein aggregation and neurotoxicity
Keywords: تیوفلاین-T; Alpha-synuclein; Antibodies; Intravenous immunoglobulin; Oligomers; Thioflavin-T; Western blots;
'Click peptide' using production of monomer Aβ from the O-acyl isopeptide: Application to assay system of aggregation inhibitors and cellular cytotoxicity
Keywords: تیوفلاین-T; Aggregation; Amyloid; Alzheimer; Click peptide; Inhibitor; Isopeptide; DMEM; Dulbecco's modified Eagle's medium; DMSO; dimethyl sulfoxide; HFIP; 1,1,1,3,3,3-hexafluoro-2-propanol; Myr; myricetin; NDGA; nordihydroguaiaretic acid; Rif; rifampicin; TFA;
Aβ40(L17A/F19A) mutant diminishes the aggregation and neurotoxicity of Aβ40
Keywords: تیوفلاین-T; Aβ, β-amyloid peptide; AD, Alzheimer’s disease; CD, circular dichroism; ThT, Thioflavin-T; SDS, sodium dodecyl sulfateNMR; Thioflavin-T; β-amyloid peptide; Alzheimer’s disease
On the binding of Thioflavin-T to HET-s amyloid fibrils assembled at pH 2
Keywords: تیوفلاین-T; Thioflavin-T; Amyloid; Prion; Dye binding; HET-s; Podospora anserina
Synthesis and evaluation of a 99mTc-BAT-phenylbenzothiazole conjugate as a potential in vivo tracer for visualization of amyloid β
Keywords: تیوفلاین-T; Amyloid β; Thioflavin-T; 2-Phenylbenzothiazoles; Technetium-99m
The binding of thioflavin-T to amyloid fibrils: localisation and implications
Keywords: تیوفلاین-T; Amyloid fibrils; Thioflavin-T; Congo red; Spherulites; Confocal microscopy;