Keywords: CVDs; cardiovascular diseases; ECs; endothelial cells; VSMCs; vascular smooth muscle cells; HPTMs; histones post-translational modifications; nt; nucleotides; 5-mC; 5-methylcytosine; 5-hmC; 5-hydroxymethylcytosine; CpG; sequence of cytosine followed by a
مقالات ISI (ترجمه نشده)
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Keywords: BGN; Biglycan; COL1; Collagen type 1; COL3; Collagen type 3; CCR7; C-C chemokine receptor type 7; DCN; Decorin; ECM; Extracellular matrix; IL1B; Interleukin-1beta; MKX; Mohawk; MMP1; Matrix metalloproteinase 1; MMP2; Matrix metalloproteinase 2; MMP3; Matr
Keywords: Negative pressure wound therapy; (NPWT); IL-1 β; Interleukin 1 beta; TGF-β; Transforming growth factor beta; VEGF; Vascular endothelial growth factor; MMP1; Matrix metalloproteinase 1; TIMP1; tissue inhibitor matrix metalloproteinase 1; Diabetic foot ul
Keywords: Actb; actin beta; BBB; bloodbrain barrier; CBF; cerebral blood flow; Ccl2; chemokine (CC motif) ligand 2; cRNA; complimentary RNA; Ct; threshold cycle; Edn1; endothelin 1; FC; fold change; FDR; false discovery rate; Gapdh; glyceraldehyde-3-phosphate dehyd
Keywords: â; decrease; â; increase; MMP; matrix metalloproteinase; IAP; inhibitor of apoptosis protein; JNK; c-jun N-terminal kinase; GADD; DNA damage-inducible; COX-2; cyclooxygenase-2; PARP; poly (ADP-ribose) polymerase; EGFR; epidermal growth factor receptor
Keywords: BDNF; brain-derived neurotrophic factor; CAPRIN1; cell cycle associated protein 1; CD3D; CD3d molecule delta; CD97; CD97 molecule; CHL1; cell adhesion molecule L1-like; CLEC4A; C-type lectin domain family 4, member A; CNVs; copy-number variations; DUSP1;
Keywords: AP-1; activator protein-1; AR; acute rejection; ATG; anti-thymocyte globulin; CAN; chronic allograft nephropathy; CBP; CREB-binding protein; CREB; cyclic AMP-responsive element-binding; DBD; DNA-binding domain; F2R; coagulation factor II receptor; FKBP; F
Keywords: MRM; multiple reaction monitoring; TIMP1; tissue inhibitor of metalloproteinases 1; PTPκ; tyrosine phosphatase κ; QqQ; triple quadrupole; Q-TOF; quadrupole-time of flight; CRC; colorectal cancer; Low-abundance serological protein; Peptide affinity-based
Keywords: RNA; ribonucleic acid; PCR; polymerase chain reaction; cDNA; complementary deoxyribonucleic acid; TIMP1; Tissue Inhibitor of Metalloproteinase I; c-Myc; v-myc avian myelocytomatosis viral oncogene homolog; SPARC; secreted protein acidic and rich in cystei
Keywords: Twist; Speckle tracking; Heart failure; Hypertension; Matrix metalloproteinases; Tissue inhibitor of matrix metalloproteinase-1; AR; Apical rotation; BR; Basal rotation; ECM; Extracellular matrix; EF; Ejection fraction; HTLEF; Hypertension with low ejec
Keywords: ACAT; acyl-CoA cholesterol acyltransferase; ACC; acetyl CoA carboxylases; ACLY; ATP citrate lyases; ACSL; acyl CoA synthetases long chain family; ADRP; adipose differentiation related protein; AGP; advanced glycation end products; AGPAT; acylglycerophosph
Keywords: Toxicogenomics; Rat; Papillary injury; Timp1; Igf1; Lamc2;
BDNF mimetic alleviates body weight gain in obese mice by enhancing mitochondrial biogenesis in skeletal muscle
Keywords: 7,8-DHF; 7,8-Dihydroxyflavone; ACC; accetyl CoA carboxylase; AdipoQ; adiponectin; AMPK; AMP-activated protein kinase; ANGPT-L3; angiopoietin-like 3; BAT; brown adipose tissue; BDNF; brain derived neurotrophic factor; CREB; cAMP responsive element binding
Carnosol-mediated Sirtuin 1 activation inhibits Enhancer of Zeste Homolog 2 to attenuate liver fibrosis
Keywords: carnosol (PubChem CID:442009); resveratrol (PubChem CID:445154); DZNep; 3-Deazaneplanoci A; ALT; alanine aminotransferase; AST; aspartate aminotransferase; CS; carnosol; CCl4; carbon tetrachloride; H3K27me3; catalyzes trimethylation of lysine 27 on histon
MicroRNAs in the pathogenesis and treatment of progressive liver injury in NAFLD and liver fibrosis
Keywords: ApoB; apolipoprotein B; CBDL; common bile duct ligation; CCl4; carbon tetrachloride; CPT1; peroxisome carnitine palmitoyl transferase 1; CREBH; cAMP responsive element binding protein H; DNL; de novo lipogenesis; ECM; extracellular matrix; ER; endoplasmic
Reversal of metabolic disorders by pharmacological activation of bile acid receptors TGR5 and FXR
Keywords: Farnesoid X receptor; TGR5; Atherosclerosis; Obesity; NAFLD; α-Sma; alpha smooth muscle actin (α-Sma); BA; bile acid; BAT; brown adipose tissue; CEBPα; CCAAT/enhancer-binding protein α; Col1α1; collagen type 1 α1; DIO; diet-induced obesity; FXR; far
Identification of circular RNAs in human aortic valves
Keywords: AGO; argonaute; ANK3; ankyrin 3; BAV; bicuspid aortic valve; CASP3; Caspase-3; circRNA; circular RNA; COL6A6; collagen, type VI, alpha 6; ECM; extracellular matrix; ERBB4; V-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4; FBN; fibrillin 1;
VAMP8, a vesicle-SNARE required for RAB37-mediated exocytosis, possesses a tumor metastasis suppressor function
Keywords: RAB37; VAMP8; TIMP1; Exocytosis; Metastasis; Prognosis; CM; conditional medium; IF; immunofluorescence; IHC; immunohistochemistry; IP; immunoprecipitation; SNAREs; soluble N-ethylmaleimide-sensitive factor activating protein receptors; TIMP1; tissue inhib
Astaxanthin: A mechanistic review on its biological activities and health benefits
Keywords: Astaxanthin (PubChem CID: 5368397); Beta-Carotene (PubChem CID: 5280489); Beta-Cryptoxanthin (PubChem CID: 5281235); Canthaxanthin (PubChem CID: 5281227); Lutein (PubChem CID: 5281243); Zeaxanthin (PubChem CID: 5280899); Alpha-Tocopherol (PubChem CID: 149
DNA methylation of extracellular matrix remodeling genes in children exposed to arsenic
Keywords: Arsenic; Children; DNA methylation; MMP9; TIMP1; RAGE;
Anti-fibrotic effects of chronic treatment with the selective FXR agonist obeticholic acid in the bleomycin-induced rat model of pulmonary fibrosis
Keywords: ACE2; angiotensin I converting enzyme 2; AGT; angiotensinogen; ATI; alveolar epithelial cells type I; ATII; alveolar epithelial cells type II; BALF; bronchial alveolar lavage fluid; BMP2; bone morphogenetic protein 2; BMPR1A; bone morphogenetic protein re
MHC IIâ, but not MHC II+, hepatic Stellate cells contribute to liver fibrosis of mice in infection with Schistosoma japonicum
Keywords: HSCs; hepatic stellate cells; FCM; flow cytometry; MHC II; major histocompatibility complex class II; α-SMA; alpha-smooth muscle actin; Col1α1; Collagen1α1; Timp1; tissue inhibitor of metalloproteinase-1; PD-L1; programmed death ligand 1; LRAT; lecithi
Pancreatic Premalignant Lesions Secrete Tissue Inhibitor of Metalloproteinases-1, Which Activates Hepatic Stellate Cells Via CD63 Signaling to Create a Premetastatic Niche in the Liver
Keywords: Tissue Inhibitor of Metalloproteinases; Tumor Progression; Signal Transduction; Microenvironment; CP; chronic pancreatitis; HSC; hepatic stellate cell; PanIN; pancreatic intra-epithelial neoplasia; PDAC; pancreatic ductal adenocarcinoma; PDGF-B; platelet-
Cardiac concentric hypertrophy promoted by activated Met receptor is mitigated in vivo by inhibition of Erk1,2 signalling with Pimasertib
Keywords: CVD; cardiovascular disease; CHF; congestive heart failure; ctrl; control; DOX; doxycycline; ECM; Extracellular Matrix; LV; lentiviral; HFpEF; heart failure with preserved ejection function; Hgf; hepatocyte growth factor; HCM; hypertrophic cardiomyopathy;
TIMP1 in conditioned media of human adipose stromal cells protects neurons against oxygen-glucose deprivation injury
Keywords: Adipose stromal cells; Oxygen-glucose deprivation; TIMP1;
Neuroprotective effects and dynamic expressions of MMP9 and TIMP1 associated with atorvastatin pretreatment in ischemia-reperfusion rats
Keywords: Atorvastatin; Ischemia-reperfusion; MMP9; TIMP1; Rats; MCAo; Pretreatment;
Inhibition of MEF2A prevents hyperglycemia-induced extracellular matrix accumulation by blocking Akt and TGF-β1/Smad activation in cardiac fibroblasts
Keywords: MEF2A; myocyte enhancer factor 2A; CFs; cardiac fibroblasts; NG; normal glucose; HG; high glucose; OC; osmotic control; MAPK; mitogen-activated protein kinases; shRNAs; short-hairpin RNAs; RNAi; RNA interference; STZ; streptozotocin; MOI; multiplicity of
Multi-faceted integrated omics analysis revealed parsley (Petroselinum crispum) as a novel dietary intervention in dextran sodium sulphate induced colitic mice
Keywords: AA; amino acid; Ala; alanine; Asn; asparagine; Asp; aspartic acid; Arg1; arginase 1; Ccl; chemokine (C-C motif) ligand; Cebp/d; CCAAT/enhancer binding protein (C/EBP), delta; Cd163; cluster of differentiation 163; Cxcl; chemokine (C-X-C motif) ligand; DAI
Including osteoprotegerin and collagen IV in a score-based blood test for liver fibrosis increases diagnostic accuracy
Keywords: A2M; alpha-2-macroglobulin; ApoA1; apolipoprotein A1; AST; aspartate aminotransferase; AUROC; area under receiver operating characteristic curve; BMI; body mass index; C-IV; collagen IV; CHC; chronic hepatitis C; CI; confidence interval; CS; Coopscore©;
Thymic stromal lymphopoietin downregulates NME1 expression and promotes invasion in human trophoblasts via the activation of STAT3 signaling pathway
Keywords: TSLP; NME1; TIMP1; STAT3 pathway; Trophoblast invasion
Chitooligosaccharide ameliorates diet-induced obesity in mice and affects adipose gene expression involved in adipogenesis and inflammation
Keywords: ANOVA; analysis of variance; cDNA; complementary DNA; Ctsk; cathepsin K; CO; chitooligosaccharide; ECM; extracellular matrix; Egr2; early growth response 2; Fasn; fatty acid synthase; FER; feed efficiency ratio; FFA; free fatty acid; Gdf3; growth differen
A fine balance between CCNL1 and TIMP1 contributes to the development of breast cancer cells
Keywords: CCNL1; TIMP1; Breast cancer; Gene expression
Cholestatic liver fibrosis and toxin-induced fibrosis are exacerbated in matrix metalloproteinase-2 deficient mice
Keywords: Bile duct ligation; Carbon tetrachloride; PDGF receptor; TIMP1; TGFβALT, alanine aminotransferase; αSMA, α smooth muscle actin; AST, aspartate aminotransferase; BDL, bile duct ligation; CCl4, carbon tetrachloride; ECM, extracellular matrix; GGT, γ-glutamy
Different expression of tissue inhibitor of metalloproteinase family members in rat dorsal root ganglia and their changes after peripheral nerve injury
Keywords: TIMP1; TIMP2; dorsal root ganglia; peripheral nerve injury; in situ hybridizationATF3, activating transcription factor 3; DEPC, diethyl pyrocarbonate; DRG, dorsal root ganglia; GFAP, glial fibrillary acidic protein; IL, interleukin; MMP, matrix metallopro
Toll-Like Receptor 9 Promotes Steatohepatitis by Induction of Interleukin-1β in Mice
Keywords: Nonalcoholic Fatty Liver Diseases; Toll-Like Receptors; Bacterial DNA; Bambi; ALT; alanine transaminase; ATP; adenosine triphosphate; CDAA; choline-deficient amino-acid defined; CpG; cytosine phosphate guanine; CSAA; choline-supplemented amino acid define
Kupffer Cells Mediate Leptin-Induced Liver Fibrosis
Keywords: αSMA; α-smooth muscle actin; collagen I; collagen 1α1; CTGF/CCN2; connective tissue growth factor; ERK1/2; extracellular signal-related kinase 1 and 2; KCs; Kupffer cells; HSCs; hepatic stellate cells; SECs; sinusoidal endothelial cells; TGF-β1; trans
TIMP1 induces CD44 expression and the activation and nuclear translocation of SHP1 during the late centrocyte/post-germinal center B cell differentiation
Keywords: TIMP1; CD44; SHP1; Hodgkin lymphoma
KAI1/CD82 suppresses tumor invasion by MMP9 inactivation via TIMP1 up-regulation in the H1299 human lung carcinoma cell line
Keywords: H1299 non-small cell lung carcinoma cells; KAI1/CD82; MMP9; TIMP1; Tumor invasiveness
Profiling molecular targets of TGF-β1 in prostate fibroblast-to-myofibroblast transdifferentiation
Keywords: Actg2; actin, gamma 2, smooth muscle; bFGF; basic fibroblast growth factor; Cdk; cycline-dependent kinase; Cks1; Cdc28 protein kinase 1; Comp; cartilage oligomeric matrix protein; Ctgf; connective tissue growth factor; Dkk3; dickkopf3; Elf1a; elongation f
Inhibition of inhibitor of κB kinases stimulates hepatic stellate cell apoptosis and accelerated recovery from rat liver fibrosis
Keywords: HSC; hepatic stellate cells; IκB; inhibitor of κB; IKK; inhibitor of κB kinase; IL; interleukin; JNK; Jun N-terminal kinase; MMP; matrix metalloproteinase; MPT; mitochondrial permeability transition; NBD; NEMO-binding domain; NF-κB; nuclear factor-κB
Gene profiling the response to kainic acid induced seizures
Keywords: Neurotransmitters, modulators, transporters, and receptors; Excitatory amino acids: excitotoxicity; Agt; angiotensinogen; Akt; protein kinase B; Aldr1; aldehyde reductase 1; ANPEP; alanyl aminopeptidase N; ATF4; activating transcription factor 4; Bax; BCl