Keywords: Chitosan; Nanoparticles; Bovine serum albumin; Tityus serrulatus; Protein delivery; Ionic gelation;
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Ts1 from the Brazilian scorpion Tityus serrulatus: A half-century of studies on a multifunctional beta like-toxin
Keywords: Tityus serrulatus; Brazilian scorpion venom; β-toxin; Ts1; Voltage-gated Na+ channels;
Expanding biological activities of Ts19 Frag-II toxin: Insights into IL-17 production
Keywords: Tityus serrulatus; Ts19 Frag-II; Biochemical parameters; Cytokines; IL-17; Proinflammatory;
Ts14 from Tityus serrulatus boosts angiogenesis and attenuates inflammation and collagen deposition in sponge-induced granulation tissue in mice
Keywords: BK; bradykinin; ELISA; enzyme linked immuno sorbent assay; HTAB; hexadecyltrimethylammonium bromide; MPO; myeloperoxidase; NAG; N-acetyl- β-d-glucosaminidase; NOS; nitric oxide synthase; OD; optic density; SEM; standard error of the mean; TNF-α; tumor n
[des-Arg1]-Proctolin: A novel NEP-like enzyme inhibitor identified in Tityus serrulatus venom
Keywords: Tityus serrulatus; Neprilysin (NEP); Proctolin; [des-Arg1]-proctolin; Cockroach; Scorpion venom; Neuropeptide;
Ts8 scorpion toxin inhibits the Kv4.2 channel and produces nociception in vivo
Keywords: Tityus serrulatus; Scorpion; Nociception; Pain; Kv4.2; Ion channels
Potassium channel blockers from the venom of the Brazilian scorpion Tityus serrulatus ( Lutz and Mello, 1922)
Keywords: Potassium channels; Tityus serrulatus; Scorpion toxins; BlockersMALDI-TOF MS, matrix assisted laser desorption/ionization time-of-flight mass spectrometry
Electrophysiological characterization of the first Tityus serrulatus alpha-like toxin, Ts5: Evidence of a pro-inflammatory toxin on macrophages
Keywords: Macrophage modulation; Sodium channel; Ts5; Tityus serrulatus; ToxinNav channel, voltage-gated sodium channel; Ts, Tityus serrulatus; IL, interleukin; TNF-alpha, tumor necrosis factor-alpha; PAMPs, pathogen-associated molecular patterns; DAMPs, damage-ass
A gamut of undiscovered electrophysiological effects produced by Tityus serrulatus toxin 1 on NaV-type isoforms
Keywords: Voltage-gated sodium channel; Scorpion toxin; Tityus serrulatus; Bell-shaped modulation; Ion channel modulator; Binding site;
Tityus serrulatus venom - A lethal cocktail
Keywords: Tityus serrulatus; Anatomical systems; Brazilian scorpion; Envenoming; Scorpion venom; Neurotoxins;
Tityus serrulatus scorpion venom improves survival and lung inflammation in lethal sepsis induced by CLP in mice
Keywords: Tityus serrulatus; Venom; CLP; Sepsis; Inflammation; Cytokines
Influence of post-starvation extraction time and prey-specific diet in Tityus serrulatus scorpion venom composition and hyaluronidase activity
Keywords: Diet; Tityus serrulatus; Scorpion feeding; Venom composition; Hyaluronidase; Ontogenetic variation; Ts; Tityus serrulatus; RP-FPLC; reversed-phase fast protein liquid chromatography; SDS-PAGE; Sodium Dodecyl Sulfate Polyacrylamide Gel Electrophoresis; NaS
Molecular and functional characterization of metalloserrulases, new metalloproteases from the Tityus serrulatus venom gland
Keywords: Tityus serrulatus; Metalloprotease; Metalloserrulase; Venom; Scorpion; Envenomation; MCA; 7-methoxycoumarin-4-acetic acid; TsMS; metalloserrulase; Ts; Tityus serrulatus; EDTA; ethylenediaminetetraacetic acid; DPA; Nb-(2,4-dinitrophenyl)-L-2,3-diaminopropi
Isolation, homology modeling and renal effects of a C-type natriuretic peptide from the venom of the Brazilian yellow scorpion (Tityus serrulatus)
Keywords: Tityus serrulatus; Natriuretic peptide; Kidney perfusion; Natriuretic peptide receptor; Guanylate cyclase C;
Another record of significant regional variation in toxicity of Tityus serrulatus venom in Brazil: A step towards understanding the possible role of sodium channel modulators
Keywords: Scorpion venom; Tityus serrulatus; Pulmonary edema; DL50; Na+-channel; Toxin;
Tityus serrulatus venom increases vascular permeability in selected airway tissues in a mast cell-independent way
Keywords: Airways; Edema; Mast cell; Scorpion venom; Tityus serrulatus
Serum production against Tityus serrulatus scorpion venom using cross-linked chitosan nanoparticles as immunoadjuvant
Keywords: Scorpion; Chitosan; Nanoparticles; Tityus serrulatus; Immunization;
Immune cells recruitment and activation by Tityus serrulatus scorpion venom
Keywords: Tityus serrulatus; Venom; Inflammation; Cytokines; Immunomodulatory;
Isolation and characterization of a human antibody fragment specific for Ts1 toxin from Tityus serrulatus scorpion
Keywords: Antibody; Human scFv; Phage display; Scorpion toxin; Tityus serrulatus;
Purification and characterization of Ts15, the first member of a new α-KTX subfamily from the venom of the Brazilian scorpion Tityus serrulatus
Keywords: Tityus serrulatus; Scorpion venom; Potassium channel; KTx; Kv channel; voltage-gated potassium channel; NaV channel; voltage-gated sodium channel; KTxs; voltage-gated potassium channel toxins; Tsv; Tityus serrulatus venom;
Biochemical profile of dogs experimentally envenomed with Tityus serrulatus scorpion venom
Keywords: Tityus serrulatus; Envenomation; Blood analysis; Urine analysis; Dog
Structure–function studies of Tityus serrulatus Hypotensin-I (TsHpt-I): A new agonist of B2 kinin receptor
Keywords: Bradykinin-potentiating peptide; Kinin receptor agonist; Tityus serrulatus; Hypotensins; Structure minimization
Assessment of biochemical and hematological parameters in rats injected with Tityus serrulatus scorpion venom
Keywords: Scorpion venom; Tityus serrulatus; Hematological parameters; Serum protein; Osmotic fragility; Serum electrolytesCS, complement system; Hb, hemoglobin concentration; Ht, hematocrit; MCH, mean corpuscular hemoglobin; MCHC, mean corpuscular hemoglobin conce
Inter- and intrapopulational genetic variability of Tityus serrulatus (Scorpiones, Buthidae)
Keywords: Tityus serrulatus; Scorpions; Parthenogenesis; SNPs; Cytochrome oxidase subunit 1
Effects of Tityus serrulatus scorpion venom on lung mechanics and inflammation in mice
Keywords: Tityus serrulatus; Lung inflammation; Lung mechanics; Respiratory systemTsV, Tityus serrulatus venom
Developmental effects of Tityus serrulatus scorpion venom on the rat offspring
Keywords: Scorpion venom; Tityus serrulatus; Perinatal; Neurodevelopmental disorders
Reproductive toxic effects of Tityus serrulatus scorpion venom in rats
Keywords: Scorpion venom; Tityus serrulatus; Pregnancy; Development; Fetus; Reproductive parameters
Effective Tityus serrulatus anti-venom produced using the Ts1 component
Keywords: Tityus serrulatus; Serum; Anti-venom; Ts1; TsVII; Toxin-γ; Neutralizing antibodies; Tandem; Toxin; Recombinant; cDNA; Scorpion; VenomTs1, tityustoxin I (TsVII, Ts-gamma); Ts1(1), recombinant Ts1 with one tandem copy; Ts1(2), recombinant Ts1 with two tande
Tityus serrulatus venom peptidomics: Assessing venom peptide diversity
Keywords: Tityus serrulatus; Venom; MALDI-TOF-TOF; De novo sequencing
Inflammatory mediators involved in the nociceptive and oedematogenic responses induced by Tityus serrulatus scorpion venom injected into rat paws.
Keywords: Tityus serrulatus; Scorpion; Venom; Oedema; Pain; Inflammation
Scorpion venom increases mRNA expression of lung cytokines
Keywords: Scorpion venom; Pulmonary edema; Cytokines; Chemokines; Ribonuclease protection assay; Tityus serrulatus; Messenger RNA; Interleukin-6, interleukin-1β
Platelet activating factor receptors drive CXC chemokine production, neutrophil influx and edema formation in the lungs of mice injected with Tityus serrulatus venom
Keywords: Lung edema; Tityus serrulatus; PAF receptor antagonist; CXCR2 inhibitor
Acute left ventricular dysfunction of severe scorpion envenomation is related to myocardial perfusion disturbance
Keywords: Scorpion envenomation; Left ventricular dysfunction; Myocardial perfusion scintigraphy; Tityus serrulatus;
Toxin gamma from Tityus serrulatus scorpion venom plays an essential role in immunomodulation of macrophages
Keywords: Cytokines; Immunomodulation; Macrophages; Scorpion toxin; Tityus serrulatus
Effects of Tityus serrulatus scorpion venom and its toxin TsTX-V on neurotransmitter uptake in vitro
Keywords: GABA, γ-aminobutiric acid; DA, dopamine; Glu, glutamate; Ts venom, Tityus serrulatus venom; TTX, tetrodotoxin; TsTX-V, tityustoxin-V; GAT-1, type 1 GABA transporter; GAT-3, type 3 GABA transporterScorpion venom; Tityus serrulatus; TsTX-V; Neurotransmitter
Moving pieces in a taxonomic puzzle: Venom 2D-LC/MS and data clustering analyses to infer phylogenetic relationships in some scorpions from the Buthidae family (Scorpiones)
Keywords: Buthidae phylogeny; Data clustering analyses; 2D-LC/MS; Venom proteomics; Tityus serrulatus; Tityus stigmurus; Tityus bahiensis; Leiurus quinquestriatus
Renal effects and vascular reactivity induced by Tityus serrulatus venom
Keywords: Tityus serrulatus; Perfused kidney; Mesenteric blood vessels;
Activation of the complement system and leukocyte recruitment by Tityus serrulatus scorpion venom
Keywords: AP; alternative pathway; CFD; complement fixation diluent; CP; classical pathway; CS; complement system; IC50; venom concentration inhibiting 50% of the lytic activity; NHS; normal human serum; PBS; Phosphate-buffered saline; TEA; triethanolamine; TsV; Ti
Effects of voltage-gated Na+ channel toxins from Tityus serrulatus venom on rat arterial blood pressure and plasma catecholamines
Keywords: E; epinephrine; MAP; mean arterial blood pressure; NE; norepinephrine; RP-HPLC; reverse-phase high performance liquid chromatography; TsV; Tityus serrulatus venom; Scorpion venom; Catecholamines; Blood pressure; Tityus serrulatus; TsTX-I; TsTX-V; Voltage-
Pharmacological investigation of the nociceptive response and edema induced by venom of the scorpion Tityus serrulatus
Keywords: Tityus serrulatus; Scorpion; Pain; Edema; Inflammation; Allodynia;