Keywords: Crocin; DN; Insulin; TLR-4; IL-6; ROS;
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Keywords: Curcumin; Chronic urinary tract infection; Renal tubular function; Inflammatory response; TLR-2; TLR-4;
Keywords: Liver transplantation; Machine perfusion; Preservation; HOPE; Hypothermic; Normothermic; MELD; Model of end stage liver disease; ROS; Oxygen free radicals; MPT; Mitochondrial pore transition; ER; Endoplasmic reticulum; DAMP's; Danger associated molecular
Keywords: Elderly donors; Extended criteria donors; Marginal donors; Liver transplantation; MELD; Model of end stage liver disease; ROS; Oxygen free radicals; ER; Endoplasmic reticulum; DAMP's; Danger associated molecular pattern's; KC's; Kupffer cells; TLR-4; Roll
Keywords: AD; Alzheimer's disease; ANOVA; analysis of variance; DAMPs; damage-associated molecular patterns; DCFH-DA; 2â²,7â²-dichlorofluorescein diacetate; FST; Forced swimming test; GSH; Glutathione; H&E; hematoxylin and eosin; HBT; Hole-board test; HPA; hypo
Keywords: In ovo feeding; l-Arginine; Inducible nitric oxide synthase; Mucosal immune function; DNA methylation; BW; body weight; CpG; cytosine-guanine nucleotide repeats; DG; diluent-injected control group; GALT; gut-associated lymphoid tissue; GIT; gastrointestin
Keywords: Glucocorticoid-induced leucine zipper; Lipopolysaccharide; Endotoxin-induced uveitis; Cytokine; Anterior segment inflammation; AP-1; activator protein-1; GILZ; glucocorticoid-induced leucine zipper; EIU; endotoxin-induced uveitis; ELISA; enzyme-linked imm
Keywords: Seaweed; TLR-4; MUC2; Tight junction; Caecum;
Keywords: AGEs; advanced glycation end products; ATM; Adipose tissue macrophage; CCL; chemokine (C-C motif) ligand; CCR2; chemokine (C-C motif) receptor 2; CX3CL1; chemokine (C-X3-C motif) ligand 1; CX3CR1; chemokine (C-X3-C motif) receptor 1; CXCL; CXC chemokine l
Keywords: ADH; adipic acid dihydrazide; AUNPs; gold nanoparticles; BA; butyric acid; CDDP; cisplatin; CHI; chitosane; CNTs; carbon nanotubes; CPT; camptothecin; CSCs; cancer stem cells; DiPhPE; diphytanoyl-sn-glycero-3-glycerophosphatidyl ethanolamine; DL; drug loa
Keywords: PA; palmitic acid; TNF-α; tumor necrosis factor alpha; NFκB; nuclear factor-kappa B; OXA; orexin A/hypocretin 1; OX1R; orexin receptor 1; OX2R; orexin receptor 2; IL-6; interleukin 6; LPS; lipopolysaccharide; TLR-4; toll like receptor 4; RT-PCR; real ti
Keywords: DSS; Dextran sodium sulfate; FO; Fish oil; IF; Intestinal failure; IFALD; Intestinal failure-associated liver disease; ILE; Intravenous lipid emulsion; LPS; Lipopolysaccharides; PN; Parenteral nutrition; PNAC; Parenteral nutrition-associated cholestas
Keywords: Ischemia/reperfusion (lung); reoxygenation; TLR-2; TLR-4; proinflammatory mediators; CINC; cytokine-induced neutrophil chemoattractant; LIRI; lung ischemia reperfusion injury; MAPK; mitogen-activated protein kinase; RPMI; Roswell Park Memorial Institute;
Keywords: HFS; high-fat sucrose; TJPs; tight-junction proteins; HOMA-IR; homeostasis model assessment of insulin resistance; LPS; lipopolysaccharide; LBP; LPS-binding protein; IL-18; interleukin- 18; NFκβ; nuclear factor kappa β; TNF-α; tumour necrosis factor Î
Keywords: 4-HNE; 4-hydroxynonenal; ALT; alanine-aminotransferase; Arg-1; arginase 1; iNOS; inducible nitric oxide synthase; IR; insulin receptor; IRS-1; insulin receptor substrate 1; MCP-1; monocyte chemotactic protein 1; MyD88; myeloid differentiation primary resp
Keywords: Ovariectomy; Hypothalamus; IL-1β; TNF-α; IL-6; TLR-4;
Keywords: Bipolar disorders; Innate immunity; TLR-4; Polymorphism;
Keywords: Aortic stenosis; Valve interstitial cell; TLR-4
Keywords: TLRs; toll-like receptors; LPS; lipopolysaccharide; IT; intratracheal; PCR; polymerase chain reaction; IHC; immunohistochemistry; Ct; threshold cycle; b-HABP; biotinylated hyaluronan binding protein; BMDMs; bone marrow derived macrophages; Has; hyaluronan
Keywords: TLR-4; Inflammation; Alzheimer; Parkinson; Multiple sclerosis; Amyotrophic lateral sclerosis;
Keywords: Crossbred cows; Leukocyte activity; Real time PCR; IL-8; TNF-α; TLR-4;
Keywords: CLP; cecal ligation and puncture; EA; electroacupuncture; -MWM; Morris water maze; MDA; malondialdehyde; SOD; superoxide dismutase; CAT; catalase; TLR-4; toll-like receptor-4; NFκB; nuclear factor-kappa B; Iba 1; ionized calcium binding adaptor molecul
Dangguishaoyao-San attenuates LPS-induced neuroinflammation via the TLRs/NF-κB signaling pathway
Keywords: DSS; Dangguishaoyao-San; AD; Alzheimer's disease; LPS; lipopolysaccharide; Aβ; amyloid β; NF-κB; nuclear factor κB; IκB; inhibitor of NF-κB; TLR-2; toll-like receptor-2; TLR-4; toll-like receptor-4; TNF-α; tumor necrosis factor-α; iNOS; inducibl
Cathelicidin-WA polarizes E. coli K88-induced M1 macrophage to M2-like macrophage in RAW264.7 cells
Keywords: CWA; cathelicidin-WA; AMP; antimicrobial peptide; STAT1; signal transducer and activator of transcription 1; p-STAT1; phosphorylated signal transducer and activator of transcription 1; STAT6; signal transducer and activator of transcription 6; p-STAT6; ph
Hyaluronan in experimental injured/inflamed cartilage: In vivo studies
Keywords: ACAN; aggrecan; ADAMTS-5; A disintegrin and metalloproteinase with thrombospondin motifs 5; A2AR; adenosine type 2 receptor; Bax; BCL2 associated X protein; Bcl-2; B-cell lymphoma 2; CD44; cluster determinant 44; Col2A; collagen type II alpha; Col1a1; col
Ferulic acid protects lipopolysaccharide-induced acute kidney injury by suppressing inflammatory events and upregulating antioxidant defenses in Balb/c mice
Keywords: AKI; acute kidney injury; ANOVA; analysis of variance; BCA; bicinchoninic acid; BSA; bovine serum albumin; BUN; blood urea nitrogen; CAT; catalase; CD4; cluster of differentiation 4; CDNB; 1-chloro-2, 4-dinitrobenzene; COX-2; cycloxygenase-2; DAPI; 4â²,6
The proteoglycan biglycan mediates inflammatory response by activating TLR-4 in human chondrocytes: Inhibition by specific siRNA and high polymerized Hyaluronan
Keywords: Biglycan; Hyaluronan; NF-kB; TLR-4; Cytokines; Inflammation; Chondrocytes; siRNA;
Cholemic nephropathy - Historical notes and novel perspectives
Keywords: AKI; acute kidney injury; CBDL; common bile duct ligation; CKD; chronic kidney disease; CN; cholemic nephropathy; FXR; farnesoid X receptor; GFR; glomerular filtration rate; IL-18; interleukin 18; iNOS; inducible nitric oxide synthase; KDIGO; Kidney Disea
Inhibition of semicarbazide-sensitive amine oxidase reduces atherosclerosis in apolipoprotein E-deficient mice
Keywords: A7r5 hSSAO/VAP-1 cells; A7r5 cells overexpressing VAP-1/SSAO; AGE; advanced glycation end product; ALE; advanced lipoxidation end product; ALT; alanine transaminase; ApoE; apolipoprotein E; AST; aspartate aminotransferase; BMI; body mass index; CAD; coron
Activation of neonatal microglia can be influenced by other neural cells
Keywords: P; postnatal day; LPS; lipopolysaccharide; IL-1β; interleukin-1β; IL-6; interleukin-6; TLR-4; Toll-like receptor 4; CD11b/c; cluster differentiation factor 11b/c; E. coli; Escherichia coli; DPBS; Dulbecco's phosphate buffered saline; qPCR; quantitativ
In vivo and in vitro anti-sepsis effects of physcion 8-O-β-glucopyranoside extracted from Rumex japonicus
Keywords: Anti-sepsis; TLR-4; TLR-2; Pro-inflammatory cytokines; LPS;
The common genetic variants in IL-1Î and IL-1RN may have no predisposition to alcoholic liver disease: A meta-analysis
Keywords: ALD; alcoholic liver disease; AWLD; alcoholics without liver disease; ALC; alcoholic liver cirrhosis; CD14; cluster of differentiation 14; CIs; confidence intervals; HCs; healthy controls; IL-1β; interleukin-1β; IL1-Ra; interleukin-1 receptor antagonist
Research articleDexmedetomidine confers neuroprotection against transient global cerebral ischemia/reperfusion injury in rats by inhibiting inflammation through inactivation of the TLR-4/NF-κB pathway
Keywords: Inflammation; Dexmedetomidine; Neuroprotection; TLR-4; NF-κB;
Synthesis and immunological evaluation of a low molecular weight saccharide with TLR-4 agonist activity
Keywords: Agonist; LPS; Saccharide synthesis; TLR-4; Innate immunity;
Full-length ArticleActivation of μ-opioid receptor and Toll-like receptor 4 by plasma from morphine-treated mice
Keywords: Morphine; TLR-4; μ-Opioid receptor; TNFα;
Chronic nicotine treatment decreases LPS signaling through NF-κB and TLR-4 modulation in the hippocampus
Keywords: Nicotine; LPS; NF-κB; α7 nicotinic acetylcholine receptors; Hippocampus; TLR-4;
Anti-inflammatory effect of Cortex Eucommiae via modulation of the toll-like receptor 4 pathway in lipopolysaccharide-stimulated RAW 264.7 macrophages
Keywords: CE; Cortex Eucommiae; LPS; lipopolysaccharide; HPLC; high-performance liquid chromatography; RT-PCR; reverse transcriptase-polymerase chain reaction; IC50; inhibitory concentration of 50%; TLR-4; toll-like receptor 4; Myd88; myeloid differentiation primar
Treatment with Quinoline-3-carboxamide does not successfully prevent immune-mediated glomerulonephritis in mice
Keywords: TLR-4; toll-like receptor 4; ANCA; Anti-neutrophil cytoplasm antibody associated vasculitis; AAV; Anti-neutrophil cytoplasm antibody associated vasculitis; SLE; systemic lupus erythematosus; RA; rheumatoid arthritis; MS; multiple sclerosis; RAGE; advanced
A phase 1a, first-in-human, randomized study of a respiratory syncytial virus F protein vaccine with and without a toll-like receptor-4 agonist and stable emulsion adjuvant
Keywords: ELISA; enzyme-linked immunosorbent assay; ELISPOT; enzyme-linked immunospot; GLA; glucopyranosyl lipid A; GLA-SE; glucopyranosyl lipid A in stable emulsion; IFN-γ; interferon gamma; MN; microneutralizing; PCA; palivizumab competitive antibodies; SE; stab
Impact of Saccharomyces cerevisiae fermentation product and subacute ruminal acidosis on production, inflammation, and fermentation in the rumen and hindgut of dairy cows
Keywords: ADF; acid detergent fiber; DM; dry matter; DMI; dry matter intake; FCM; fat corrected milk; Hp; haptoglobin; IL-6; interleukin-6; LBP; LPS binding protein; LPS; lipopolysaccharide; NDF; neutral detergent fiber; SAA; serum amyloid A; SARA; subacute ruminal
Cardiac fibroblast cytokine profiles induced by proinflammatory or profibrotic stimuli promote monocyte recruitment and modulate macrophage M1/M2 balance in vitro
Keywords: Cardiac fibroblast; TLR-4; TGF-β1; Macrophage polarization;
Imidacloprid induced histomorphological changes and expression of TLR-4 and TNFα in lung
Keywords: Imidacloprid; Lungs; TLR-4; TNF-α;
Beta-2-microglobulin (B2M) expression in the urinary sediment correlates with clinical markers of kidney disease in patients with type 1 diabetes
Keywords: Diabetic kidney disease; Diabetic nephropathy; Urinary sediment; Beta-2-microglobulin; Focal segmental glomerulosclerosis; ACEI; (angiotensin converting enzyme inhibitors); ACR; (albumin-to-creatinine ratio); AGE; (advanced glycation end products); ARB; (
Mycobacterium indicus pranii (MIP) mediated host protective intracellular mechanisms against tuberculosis infection: Involvement of TLR-4 mediated signaling
Keywords: TLR-4; Mycobacterium indicus pranii; MAP kinase; Cytokine; Tuberculosis;
Knockdown of interleukin-1α does not attenuate LPS-induced production of interleukin-1β in mouse macrophages
Keywords: IL-1α; IL-1β; Macrophages; TLR-4; LyzMCre
Coriolus versicolor mushroom polysaccharides exert immunoregulatory effects on mouse B cells via membrane Ig and TLR-4 to activate the MAPK and NF-κB signaling pathways
Keywords: CVP; Coriolus versicolor mushroom polysaccharides; LPS; lipopolysaccharide; TLR4; Toll-like receptor 4; Coriolus versicolor mushroom polysaccharides (CVP); Leukocytes; Immunopotentiating effects; B cell antigen-receptor (BCR); TLR-4;
Methylglycol chitosan and a synthetic TLR4 agonist enhance immune responses to influenza vaccine administered sublingually
Keywords: Flu; influenza; MGC; methylglycol chitosan; IM; intramuscular; ID; intradermal; IN; intranasal; SL; sublingual; Ig; immunoglobulin; HA; hemagglutinin; NA; neuraminidase; AGP; aminoalkyl glucosaminide 4-phosphate; TLR4; toll-like receptor 4; MGC-CRX-601; M
Regular ArticleFullerenols and glucosamine fullerenes reduce infarct volume and cerebral inflammation after ischemic stroke in normotensive and hypertensive rats
Keywords: OH-F; fullerenol; GlcN; glucosamine; GlcN-F; glucosamine fullerene; WKY; Wistar-Kyoto-rats; SHR; spontaneously hypertensive rats; tMCAO; transient middle cerebral artery occlusion; TLR-4; toll-like receptor 4; IL-1 β; interleukin 1 β; TNF-α; tumor necr
Evaluation of in situ expression of effector and regulatory cytokines, TLR, galectins and matrix metalloproteinases in oral manifestations of paracoccidioidomycosis
Keywords: FoxP3; forkhead box P3; Gal-1; galectin 1; Gal-3; galectin 3; Gal-9; galectin 9; IL-4; interleukin-4; IL-10; interleukin-10; IL-17; interleukin-17; IFN-γ; interferon-gamma; GM-CSF; granulocytemacrophage colony-stimulating factor; MMPs; matrix metalloprot
3,4-Dihydroxy-benzohydroxamic acid (Didox) suppresses pro-inflammatory profiles and oxidative stress in TLR4-activated RAW264.7 murine macrophages
Keywords: RAW264.7 cells; TLR-4; Didox; Oxidative stress; Inflammation; iNOS;