Electrospray ionization tandem mass spectrometric studies of copper and iron complexes with tobramycin
Keywords: ترومایسین; ESI-MS; Cu(II); Fe(III); Tobramycin; Tandem mass
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Improved reversed phase liquid chromatographic method with pulsed electrochemical detection for tobramycin in bulk and pharmaceutical formulation
Keywords: ترومایسین; Liquid chromatography-Pulsed electrochemical detection; Tobramycin; Aminoglycoside antibiotics
Pharmacokinetic and tolerability profiles of tobramycin nebuliser solution 300 mg/4 ml administered by PARI eFlow® rapid and PARI LC Plus® nebulisers in cystic fibrosis patients
Keywords: ترومایسین; Tobramycin; Nebulisation; Pharmacokinetics; Safety and tolerability; Cystic fibrosis; Chronic infection; Pseudomonas aeruginosaAUC0-t, area under the curve from time 0 to the last measured time-point; CF, cystic fibrosis; CI, confidence interval; Cmax, ma
Carrier-free combination for dry powder inhalation of antibiotics in the treatment of lung infections in cystic fibrosis
Keywords: ترومایسین; Dry powder inhaler (DPI); Antibiotics; Tobramycin; Clarithromycin; Spray-drying; Carrier-free
Effects of azithromycin in Pseudomonas aeruginosa burn wound infection
Keywords: ترومایسین; Burn; Burn wound; Pseudomonas aeruginosa; Thermal injury; Azithromycin; Tobramycin; Ciprofloxacin; Biofilm; Drug–drug interaction; Cystic fibrosis
New Co-Spray-Dried Tobramycin Nanoparticles-Clarithromycin Inhaled Powder Systems for Lung Infection Therapy in Cystic Fibrosis Patients
Keywords: ترومایسین; pulmonary drug delivery; formulation; spray drying; nanoparticles; aerosol; dry powder inhaler; antibiotic; tobramycin; clarithromycin;
Population Pharmacokinetics of Tobramycin in Horses
Keywords: ترومایسین; Horses; Population pharmacokinetics; Tobramycin
Validation of the Treatment Satisfaction Questionnaire for Medication in patients with cystic fibrosis
Keywords: ترومایسین; Cystic fibrosis; Tobramycin; Patient satisfaction; Patient compliance; Questionnaires
A network meta-analysis of the efficacy of inhaled antibiotics for chronic Pseudomonas infections in cystic fibrosis
Keywords: ترومایسین; Cystic fibrosis; Pseudomonas aeruginosa; Inhaled antibiotics; Tobramycin; Network metaanalysis;
Optimization of capillary electrophoresis method with contactless conductivity detection for the analysis of tobramycin and its related substances
Keywords: ترومایسین; Aminoglycosides; CE-C4D; Tobramycin; Pharmaceutical analysis; Quality control
Liposaccharide-based nanoparticulate drug delivery system
Keywords: ترومایسین; Charged liposaccharide; Microcalorimetry; Tobramycin; Absorption enhancer; Nanoparticle; Drug delivery;
Development and characterization of anionic liposaccharides for enhanced oral drug delivery
Keywords: ترومایسین; Anionic liposaccharide; Tobramycin; Absorption enhancer; Drug delivery; Microcalorimetry
Lung deposition of inhaled tobramycin with eFlow rapid/LC Plus jet nebuliser in healthy and cystic fibrosis subjects
Keywords: ترومایسین; Cystic fibrosis; Nebuliser; Tobramycin; Aerosol; Pharmacokinetics; Pharmacoscintigraphy
Disposable versus reusable jet nebulizers for cystic fibrosis treatment with tobramycin
Keywords: ترومایسین; Tobramycin; Nebulizer; Aerosol
Amphiphilic ion pairs of tobramycin with lipoamino acids
Keywords: ترومایسین; Tobramycin; Lipoamino acids; Amphiphilicity; Hydrophobicity; Antimicrobial activity; Gram negative bacteria
Determination of tobramycin in soil by HPLC with ultrasonic-assisted extraction and solid-phase extraction
Keywords: ترومایسین; Tobramycin; Soil; Ultrasonic-assisted extraction; Solid-phase extraction; Pre-column derivatization
A simple and rapid high-performance liquid chromatographic method for determining tobramycin in pharmaceutical formulations by direct UV detection
Keywords: ترومایسین; Amino glycoside; derivatization; isocratic; reverse phase chromatography; tobramycin;
Pulmonary drug delivery systems for antimicrobial agents: facts and myths
Keywords: ترومایسین; Antibiotics; Colistimethate; Delivery system; Nebulisation; Tobramycin
Synergism and postantibiotic effect of tobramycin and Melaleuca alternifolia (tea tree) oil against Staphylococcus aureus and Escherichia coli
Keywords: ترومایسین; Post antibiotic effect; Tea tree oil; Melaleuca alternifolia; Tobramycin; Synergism
Simultaneous quantitation of tobramycin and colistin sulphate by HPLC with evaporative light scattering detection
Keywords: ترومایسین; Tobramycin; Colistin sulphate; Pharmaceutical formulation; HPLC; ELSD
Characterization of impurities in tobramycin by liquid chromatography–mass spectrometry
Keywords: ترومایسین; Tobramycin; LC–MS; Impurity characterization
Determination of kanamycin A, amikacin and tobramycin residues in milk by capillary zone electrophoresis with post-column derivatization and laser-induced fluorescence detection
Keywords: ترومایسین; Capillary zone electrophoresis; Post-column derivatization; Laser-induced fluorescence; Aminoglycosides; Kanamycin A; Amikacin; Tobramycin
Bismuth–thiol incorporation enhances biological activities of liposomal tobramycin against bacterial biofilm and quorum sensing molecules production by Pseudomonas aeruginosa
Keywords: ترومایسین; Liposomes; Tobramycin; Bismuth; Cystic fibrosis; Quorum sensing; Sputum
Preparation and characterization of spray-dried tobramycin powders containing nanoparticles for pulmonary delivery
Keywords: ترومایسین; Dry powder inhalation (DPI); Nanoparticles; Spray-drying; Pulmonary delivery; Tobramycin
Aminoglycoside therapy against Pseudomonas aeruginosa in cystic fibrosis: A review
Keywords: ترومایسین; Cystic fibrosis; Pseudomonas aeruginosa; Aminoglycoside; Tobramycin
Near InfraRed Spectroscopy homogeneity evaluation of complex powder blends in a small-scale pharmaceutical preformulation process, a real-life application
Keywords: ترومایسین; Near InfraRed Spectroscopy; Chemometrics; Powder blend homogeneity; Paediatrics; Colimycin; Tobramycin
Sprayâdried carrierâfree dry powder tobramycin formulations with improved dispersion properties
Keywords: ترومایسین; dry powder inhaler (DPI); tobramycin; sprayâdrying; pulmonary delivery; carrier free; amorphous;
Efficacy and safety of intravenous meropenem and tobramycin versus ceftazidime and tobramycin in cystic fibrosis
Keywords: ترومایسین; Cystic fibrosis; Ceftazidime; Meropenem; Tobramycin; Safety
HPLC determination of tobramycin in a simulated body fluid
Keywords: ترومایسین; Tobramycin; Carbonated-hydroxyapatite; HPLC; Release kinetics; Simulated body fluid
In vivo efficacy of humanised intermittent versus continuous ceftazidime in combination with tobramycin in an experimental model of pseudomonal pneumonia
Keywords: ترومایسین; Pseudomonas infection; Ceftazidime; Continuous infusion; Tobramycin; Pharmacodynamics
Pharmacokinetic variability of extended interval tobramycin in burn patients
Keywords: ترومایسین; Tobramycin; Pharmacokinetics; Burn; Therapeutic drug monitoring; Nosocomial infection; Aminoglycoside; Critically ill patients; Distribution volume
Simple and sensitive method for quantification of low tobramycin concentrations in human plasma using HPLC–MS/MS
Keywords: ترومایسین; Tobramycin; Sisomicin; HPLC–MS/MS; Selective decontamination of the digestive tract
Identification of tobramycin impurities for quality control process monitoring using high-performance anion-exchange chromatography with integrated pulsed amperometric detection
Keywords: ترومایسین; HPAE-PAD; HPAE-IPAD; HPLC; Tobramycin; Kanamycin B; Kanamycin A; Neamine; Neomycin A; Carbamoyl-kanamycin B; Carbamoyl-tobramycin; 2-Deoxystreptamine; Deoxystreptamine–kanosaminide; Kanosamine; Nebramine; Fermentation; Purity; Nebramycin; Aminoglycoside;
Positive antibacterial co-action between hop (Humulus lupulus) constituents and selected antibiotics
Keywords: ترومایسین; Humulus lupulus; Lupulone; Xanthohumol; Polymyxin B; Ciprofloxacin; Tobramycin; Synergistic effects
Development and validation of HPLC method for the determination of tobramycin in urine samples post-inhalation using pre-column derivatisation with fluorescein isothiocyanate
Keywords: ترومایسین; Tobramycin; Fluorescein isothiocyanate (FITC); HPLC; Assay; Validation; Urinary pharmacokinetic
Pharmacoscintigraphic and pharmacokinetic evaluation of tobramycin DPI formulations in cystic fibrosis patients
Keywords: ترومایسین; Dry powder inhaler; Cystic fibrosis; Tobramycin; Gamma scintigraphy; Pharmacokinetics
Two nucleotide substitutions in the A-site of yeast 18S rRNA affect translation and differentiate the interaction of ribosomes with aminoglycoside antibiotics
Keywords: ترومایسین; Ribosomal RNA; Translational fidelity; Footprinting analysis; Paromomycin; Tobramycin; Saccharomyces cerevisiaeeEF1, eukaryotic elongation factor 1; eEF2, eukaryotic elongation factor 2; Ac-Phe-tRNA, N-acetyl-phenylalanyl-tRNA
Comparison of the pharmacokinetics of five aminoglycoside and aminocyclitol antibiotics using allometric analysis in mammal and bird species
Keywords: ترومایسین; Allometric analysis; Gentamicin; Amikacin; Tobramycin; Kanamycin; Apramycin
Generic simple enzyme immunoassay approach to avert small molecule immobilization problems on solid phases
Keywords: ترومایسین; Enzyme immunoassay; Non-competitive binding; Aminoglycoside antibiotics; Tobramycin; Therapeutic drug monitoring;
Population pharmacokinetics of tobramycin administered thrice daily and once daily in children and adults with cystic fibrosis
Keywords: ترومایسین; Tobramycin; Pharmacokinetics; Diurnal variation
Nebulisers comparison with inhaled tobramycin in young children with cystic fibrosis
Keywords: ترومایسین; Child; Cystic fibrosis; Nebulisation; Pulmonary deposition; Tobramycin
Measurement of urinary N-acetyl-b-d-glucosaminidase in adult patients with cystic fibrosis: Before, during and after treatment with intravenous antibiotics
Keywords: ترومایسین; Cystic fibrosis (CF); N-acetyl-b-d-glucosaminidase (NAG); Tobramycin; Colistin sulphomethate (colistin); Renal damage; Cystic fibrosis related diabetes (CFRD)
Direct selection of RNA beacon aptamers
Keywords: ترومایسین; RNA; Aptamer; Beacon; In vitro selection; Tobramycin; Fluorescence
Measurement of tobramycin by reversed-phase high-performance liquid chromatography with mass spectrometry detection
Keywords: ترومایسین; Tobramycin; Aminoglycoside; pH stable C18 column; HPLC
Potentiometric assessment of Gram-negative bacterial permeabilization of tobramycin
Keywords: ترومایسین; Sensor; Potentiometric determination; Tobramycin; β-cyclodextrin; Bacterial permeabilization
Determination of tobramycin and impurities using high-performance anion exchange chromatography with integrated pulsed amperometric detection
Keywords: ترومایسین; HPAE-PAD; HPAE-IPAD; Tobramycin; Kanamycin B; Neamine; Neomycin A; Aminoglycoside; Antibiotic; Electrochemical detection; Anion-exchange; Chromatography
In-vivo impact of the MexXY efflux system on aminoglycoside efficacy in an experimental model of Pseudomonas aeruginosa pneumonia treated with tobramycin
Keywords: ترومایسین; Efflux; MexXY; pneumonia; Pseudomonas aeruginosa; rabbit model; tobramycin
Effects of N-trimethylchitosan on transcellular and paracellular transcorneal drug transport
Keywords: ترومایسین; Dexamethasone; Tobramycin; N-Trimethylchitosan; Transcorneal absorption; Absorption enhancer; Transcellular transport; Paracellular transport; Ocular drug delivery; Mucosal delivery; Polymeric biomaterials
The in vitro elution characteristics of vancomycin and tobramycin from calcium sulfate beads
Keywords: ترومایسین; calcium sulfate; antibiotic beads; vancomycin; tobramycin;
Pharmacodynamics of tobramycin in patients with cystic fibrosis
Keywords: ترومایسین; Tobramycin; Pharmacodynamics; Clinical efficacy; Cystic fibrosis;