دانلود مقالات ISI درباره Tp53 + ترجمه فارسی

Co-targeting hexokinase 2-mediated Warburg effect and ULK1-dependent autophagy suppresses tumor growth of PTEN- and TP53-deficiency-driven castration-resistant prostate cancer

Keywords: Warburg effect; Autophagy; PTEN; TP53; Hexokinase 2; AMPK; ULK-1; MCL-1; 2-Deoxy-glucose; Chloroquine; Androgen receptor; Castration-resistant prostate cancer; Genetically-engineered mouse model

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

TP53 and lacZ mutagenesis induced by 3-nitrobenzanthrone in Xpa-deficient human TP53 knock-in mouse embryo fibroblasts

Keywords: TP53; Mutation; Nucleotide excision repair; 3-Nitrobenzanthrone; DNA adduct; Environmental carcinogen;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

Novel roles of androgen receptor, epidermal growth factor receptor, TP53, regulatory RNAs, NF-kappa-B, chromosomal translocations, neutrophil associated gelatinase, and matrix metalloproteinase-9 in prostate cancer and prostate cancer stem cells

Keywords: AR; EGFR; TP53; Regulatory RNAs; NGAL; MMP-9;

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2016 سفارش ترجمه

Overexpression of stathmin/oncoprotein 18 correlates with poorer prognosis and interacts with p53 in oral squamous cell carcinoma

Keywords: Stathmin; Oral squamous cell carcinoma; Biomarker; TP53; TCGA; Prognosis;

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2016 سفارش ترجمه

Toll-like receptor-3 mediates HIV-1 transactivation via NFκB and JNK pathways and histone acetylation, but prolonged activation suppresses Tat and HIV-1 replication

Keywords: TLR3; HIV; Viral transactivation; LTR; NFκB; JNK; STAT1; Histone acetylation; Epigenetics; Human monocyte-derived macrophages; TZM-bl; U38 cells; AP-1; activator protein-1; B2M; beta-2-microglobulin; BCA; bicinchoninic acid; CAT; chloramphenicol acetyltr

دانلود رایگان متن کامل مقاله ISI 56 صفحه سال انتشار : 2016 سفارش ترجمه

Evaluation of CTNNB1 and TP53 variability in patients with hepatocellular carcinoma and occult hepatitis B virus infection

Keywords: CTNNB1; Hepatocellular carcinoma; Occult hepatitis B; TP53

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2015 سفارش ترجمه

Effect of TP53 16-bp and β-TrCP 9-bp INS/DEL polymorphisms in relation to risk of breast cancer

Keywords: BC; breast cancer; Β-TrCP; β-transducing repeat containing protein; CRC; colorectal cancer; CI; confidence interval; F; forward; HER2; human epidermal growth factor receptor 2; INS; insertion; OR; odds ratio; PCR; polymerase chain reaction; R; reverse;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2015 سفارش ترجمه

TP53 Arg72Pro polymorphism (rs1042522) and risk of endometriosis among Asian and Caucasian populations

Keywords: TP53; Polymorphism; Endometriosis; TagSNPs; Linkage disequilibrium

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

PI3K/mTOR pathway inhibition overcomes radioresistance via suppression of the HIF1-α/VEGF pathway in endometrial cancer

Keywords: TP53; Phosphatidylinositol 3-kinase; Hypoxia-inducible factor-1α; Radiosensitivity; Endometrial carcinoma;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Meta-analysis of association between the TP53 Arg72Pro polymorphism and risk of endometriosis based on case–control studies

Keywords: TP53; Endometriosis; Polymorphism; Meta-analysis

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

The codon 72 polymorphism of the TP53 gene and endometriosis risk: a meta-analysis

Keywords: endometriosis; meta-analysis; polymorphism; TP53;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

A new genotoxicity assay based on p53 target gene induction

Keywords: CG; control genes; EtBr; ethidium bromide; LFS; Li-Fraumeni syndrome; MMS; methylmethane sulfonate; RT-QMPSF; reverse transcription-quantitative multiplex PCR of short fluorescent fragments; TG; target gene; 4-NQO; 4-nitroquinone-N-oxide; 5-FU; 5-fluorour

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Cutaneous basal cell carcinosarcomas: evidence of clonality and recurrent chromosomal losses

Keywords: Carcinosarcoma; Osteosarcoma; Basal cell carcinoma; Clonality; Copy number analysis; TP53

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

A mutation spectrum that includes GNAS, KRAS and TP53 may be shared by mucinous neoplasms of the appendix

Keywords: Appendiceal mucinous neoplasm; TP53; GNAS; KRAS; Mismatch repair gene; Mutation

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Beyond BRCA: New hereditary breast cancer susceptibility genes

Keywords: Hereditary breast cancer; Breast cancer susceptibility genes; TP53; PTEN; PALB2

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

SASH1, a new potential link between smoking and atherosclerosis

Keywords: Atherosclerosis; SASH1; Smoking; CCND3; CCND1; TP53; HAECs; human aortic endothelial cells; HCASMCs; human coronary artery smooth muscle cells; SASH1; SAM and SH3 domain containing 1; SAM; sterile alpha-motif; SH3; Src-homology 3; WST-1; (4-[3-(4-iodophen

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

MicroRNAs in osteosarcoma

Keywords: OS; osteosarcoma; miRNAs; microRNAs; CSCs; cancer stem cells; RNA pol; RNA polymerase; DGCR8; DiGeorge syndrome critical gene 8; RISC; RNA-induced silencing complex; Exp 5; exportin 5; Ago; argonaute; MREs; miRNA recognition elements; APE1; apurinic/apyri

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Distinct clinicopathological features of NAB2-STAT6 fusion gene variants in solitary fibrous tumor with emphasis on the acquisition of highly malignant potential

Keywords: Solitary fibrous tumor; NAB2-STAT6; TP53; PDGFRB; TERT; Mutation

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Hairy cell leukaemia-variant: Disease features and treatment

Keywords: Hairy cell leukaemia variant; TP53; MAP2K1; Gene mutations; Immunophenotype; Diagnosis; Treatment;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

YAF2 promotes TP53-mediated genotoxic stress response via stabilization of PDCD5

Keywords: PDCD5, Programmed cell death 5; YAF2, YY1-associated factor 2; ET, etoposideGenotoxic stress; PDCD5; YAF2; TP53; Apoptosis

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

TP53 mutations induced by BPDE in Xpa-WT and Xpa-Null human TP53 knock-in (Hupki) mouse embryo fibroblasts

Keywords: TP53; Mutation; Nucleotide excision repair; Benzo[a]pyrene; DNA adducts; Environmental carcinogen;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2015 سفارش ترجمه

Common Genetic Variants in 53BP1 Associated with Nonsmall-cell Lung Cancer Risk in Han Chinese

Keywords: Lung cancer; Single nucleotide polymorphism; Disease susceptibility; 53BP1; TP53

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

TP53 K351N mutation-associated platinum resistance after neoadjuvant chemotherapy in patients with advanced ovarian cancer

Keywords: Ovarian cancer; TP53; K351N mutation; Neoadjuvant chemotherapy;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Modification of comet-FISH technique by using temperature instead of chemical denaturation

Keywords: Comet-FISHComet-FISH; TP53; Temperature denaturation; Lymphocytes; Primary DNA damage; Gene fragmentation

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Malignant Transformation of a Desmoplastic Infantile Ganglioglioma in an Infant Carrier of a Nonsynonymous TP53 Mutation

Keywords: desmoplastic infantile ganglioglioma; DIG; glioblastoma; TP53;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Cell cycle kinetics, apoptosis rates, DNA damage and TP53 gene expression in bladder cancer cells treated with allyl isothiocyanate (mustard essential oil)

Keywords: Allyl isothiocyanate; Apoptosis; Bladder cancer; Cell cycle; Genotoxicity; TP53;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Ribosomal protein deficiency causes Tp53-independent erythropoiesis failure in zebrafish

Keywords: Ribosomopathy; DBA; Ribosomal proteins; Tp53; ZebrafishDBA, Diamond-Blackfan Anemia; RP, ribosomal protein; MO, morpholino antisense oligo nucleotide; mTOR, mammalian target of rapamycin

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Acquired isochromosome 12p, somatic TP53 and PTEN mutations, and a germline ATM variant in an adolescent male with concurrent acute megakaryoblastic leukemia and mediastinal germ cell tumor

Keywords: Germ cell tumor; acute megakaryoblastic leukemia; isochromosome 12p; TP53; PTEN; ATM

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

BCL2, BCL6, IGH, TP53, and MYC protein expression and gene rearrangements as prognostic markers in diffuse large B-cell lymphoma: a study of 44 Turkish patients

Keywords: BCL2; BCL6; TP53; MYC; diffuse large B-cell lymphoma

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Genetic alterations in paediatric high grade astrocytomas

Keywords: glioblastoma; H3F3A; high grade astrocytoma; paediatric; TP53

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Mutation and expression analysis of the IDH1, IDH2, DNMT3A, and MYD88 genes in colorectal cancer

Keywords: CRC; colorectal cancer; APC; adenomatous polyposis coli; KRAS; Kirsten rat sarcoma viral oncogene homolog; TP53; tumor protein p53; IDH1; isocitrate dehydrogenase 1 (NADP +), soluble; IDH2; isocitrate dehydrogenase 2 (NADP +), mitochondrial; DNMT3A; DNA

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Prognostic, predictive abilities and concordance of BCL2 and TP53 protein expression in primary breast cancers and axillary lymph-nodes: A retrospective analysis of the Belgian three arm study evaluating anthracycline vs CMF adjuvant chemotherapy

Keywords: BCL2; TP53; Biomarkers; Breast cancer; Expression; Prognosis; BC; breast cancer; BCL2; B-cell leucemia/lymphoma 2; CMF; cyclophosphamide, methotrexate, fluorouracil regimen; EC; epirubicin, cyclophosphamide regimen; EFS; event free survival; ER; estrogen

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Significance of TP53 mutations as predictive markers of adjuvant cisplatin-based chemotherapy in completely resected non-small-cell lung cancer

Keywords: TP53; Mutations; NSCLC; Chemotherapy; Cisplatin; Randomized trial;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

TP63 and TP73 in cancer, an unresolved “family” puzzle of complexity, redundancy and hierarchy

Keywords: TP53; TP63; TP73; Development; Tumor suppressors;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

DNA double-strand breaks activate ATM independent of mitochondrial dysfunction in A549 cells

Keywords: ATM; ataxia telangiectasia mutant; DSB; double-strand break; HA; hemagglutinin antigen epitope tag; KAP1; KRAB-associated protein-1; MTS; mitochondrial targeting sequence; NLS; nuclear localization sequence; ROS; reactive oxygen species; SMC1; structural

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Induction of apoptosis through ER stress and TP53 in MCF-7 cells by the nanoparticle [Gd@C82(OH)22]n: A systems biology study

Keywords: ER; endoplasmic reticulum; ROS; reactive oxygen species; GO; gene ontology; qRT; quantitative real-time; TF; transcription factor; LTS; least trimmed squares; LMS; least median of squares; MLE; maximum likelihood estimator; HEK293T; human embryonic kidney

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

MATH, a novel measure of intratumor genetic heterogeneity, is high in poor-outcome classes of head and neck squamous cell carcinoma

Keywords: Head and neck cancer; Intratumor heterogeneity; Tumor biomarkers; Next-generation DNA sequencing; Somatic mutations; TP53; Human papillomavirus; Cigarette smoking;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

HSP27 expression in primary colorectal cancers is dependent on mutation of KRAS and PI3K/AKT activation status and is independent of TP53

Keywords: HSP27; HSP72; Oncogene induced senescence (OIS); TP53; KRAS; Activated PI3K/AKT;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

The biological features of PanIN initiated from oncogenic Kras mutation in genetically engineered mouse models

Keywords: PanIN; pancreatic intraepithelial neoplasia; PDAC; pancreatic ductal adenocarcinoma; PPP2R2A; protein phosphatase 2, regulatory subunit B, alpha; Kras; Tp53; PPP2R2A; PanIN; Pancreatic cancer;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

In vitro microarray analysis identifies genes in acute-phase response pathways that are down-regulated in the liver of chicken embryos exposed in ovo to PFUdA

Keywords: a2m; alpha-2-macroglobulin; APR; acute-phase response; cdo1; cysteine dioxygenase type I; CEH; chicken embryonic hepatocytes; cpb2; carboxypeptidase B2; DE; differentially expressed; DMSO; dimethyl sulfoxide; f2; thrombin (coagulation factor II); FDR; fal

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Pathogenesis, Diagnosis, and Management of Cholangiocarcinoma

Keywords: Cancer-Associated Fibroblasts; Distal Cholangiocarcinoma; Intrahepatic Cholangiocarcinoma; Molecular Pathogenesis; α-SMA; α-smooth muscle actin; CA19-9; carbohydrate antigen 19-9; CAF; cancer-associated fibroblast; CCA; cholangiocarcinoma; CT; computed

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2013 سفارش ترجمه

The presence of TP53 and dedifferentiation of low-grade glioma: A rare possible adverse effect of radiotherapy?

Keywords: low-grade glioma; malignant transformation; radiotherapy; secondary glioblastoma; TP53

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2013 سفارش ترجمه

Promoter polymorphisms of pri-miR-34b/c are associated with hepatocellular carcinoma

Keywords: miRNA, microRNA; pri-miRNA, primary RNA; pre-miRNA, premature miRNA; HCC, hepatocellular carcinoma; SNP, single nucleotide polymorphism; OR, odds ratio; CI, confidence intervalHepatocellular carcinoma; miR-34b/c; TP53; Polymorphism

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

The importance of codon context for understanding the Ig-like somatic hypermutation strand-biased patterns in TP53 mutations in breast cancer

Keywords: TP53; codon-bias; breast cancer; somatic hypermutation; mutagenesis

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Tp53 status as guide for the management of ethmoid sinus intestinal-type adenocarcinoma

Keywords: Intestinal-type adenocarcinoma (ITAC); TP53; Overal survival

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

TP53 mutations are common in all subtypes of epithelial ovarian cancer and occur concomitantly with KRAS mutations in the mucinous type

Keywords: Epithelial ovarian cancer; Deep-sequencing; TP53; KRAS; BRAF

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Primary cutaneous carcinosarcoma: insights into its clonal origin and mutational pattern expression analysis through next-generation sequencing

Keywords: Carcinosarcoma; Cutaneous; Biphenotypic tumors; Cancer stem cells; Tumorigenesis; Mutation; TP53; Next-generation sequencing

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Molecular cytogenetic evaluation of the efficacy of photodynamic therapy by indocyanine green in breast adenocarcinoma MCF-7 cells

Keywords: Photodynamic therapy (PDT); Indocyanine green; Laser irradiation; MCF-7; Interphase-FISH; TP53; HER-2; TOP2A

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Genetics and pharmacogenomics of diffuse gliomas

Keywords: Companion diagnostics; Glioma; 1p/19q co-deletion; IDH1; Pharmacogenomics; EGFRvIII; CGH; comparative genomic hybridization; CNA; copy number aberrations; CRC; colorectal carcinoma; CML; chronic myeloid leukemia; EGFR; epidermal growth factor receptor; FF

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Kinetics of GADD45α, TP53 and CASP3 gene expression in the rat lens in vivo in response to exposure to double threshold dose of UV-B radiation

Keywords: lens; UVR; stress sensing; GADD45α; TP53; CASP3; apoptosis;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه