Keywords: ATM; ataxia telangiectasia mutated; ATR; ATM-Rad3-related; AMPK; AMP-activated protein kinase; AD; Alzheimer's disease; ARE; antioxidant response element; ATF6; activating transcription factor 6; BiP; binding immunoglobulin protein; BRAC1; Breast cancer 1
مقالات ISI (ترجمه نشده)
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Keywords: AGBL2; ATP/GTP binding protein-like 2; BMPR1A; Bone morphogenetic protein receptor, type 1A; CLEC3B; C-type lectin domain family 3; C1QTNF1; C1q and tumor necrosis factor related protein1; DDAH1; Dimethylarginine dimethylaminohydrolase 1; DEGs; Differenti
Keywords: Sphingosine-1-phosphate; Sphingosine kinase; Estradiol; Breast cancer; FTY720/Fingolimod; ERα; estrogen receptor α; EGFR; epidermal growth factor receptor; ERE; estrogen response element; ERK; extracellular signal regulated kinase; E2; 17β-estradiol; H
Keywords: Pacific oyster; Crassostrea gigas; TRAF2; Innate immunity; MAVS
Keywords: OS; oxidative stress; ROS; reactive oxygen species; CNS; central nervous system; PD; Parkinson's disease; AD; Alzheimer's disease; GSH; reduced glutathione; GST; glutathione transferase; GSSG; glutathione disulfide; SN; substantia nigra; BSO; L-buthionine
Keywords: Breast cancer; TLR; TNF; TRAIL; TRAF2; Survival; Cigarettes; Oxidative stress;
Keywords: ATP; adenosine triphosphate; ADP; adenosine diphosphate; Cer; ceramide; ERK-1/2; extra-cellular signal-regulated kinase 1/2; HDAC; histone deacetylase; LDH; lactate dehydrogenase; S1P; sphingosine-1-phosphate; SAR; structure-activity relationship; Sph;
Keywords: ASK1; apoptosis signal-regulating kinase 1; ATF4; activating transcription factor 4; ATF6; activating transcription factor 6; Bcl-2; B-cell lymphoma 2; BiP; binding immunoglobulin protein; bZIP; basic leucine zipper; CDK; cyclin-dependent kinase; CDKI; CD
Keywords: PR; progesterone receptor; PIC; pro-inflammatory cytokines; P4; progesterone; Erk; extracellular-signal-regulated kinase 1/2; p53; protein 53; AKT; protein kinase B; TRAF2; tumor necrosis factor receptor-associated factor 2; PR-KO; PR knockout; Mif; mifep
Up-regulation of TRAF2 inhibits chondrocytes apoptosis in lumbar facet joint osteoarthritis
Keywords: TRAF2; Lumbar facet joint; Osteoarthritis; Apoptosis; Tumor necrosis factor-alpha;
CDCA3 promotes cell proliferation by activating the NF-κB/cyclin D1 signaling pathway in colorectal cancer
Keywords: Colorectal cancer; CDCA3; TRAF2; NF-κB signaling pathway; Cyclin D1; Proliferation;
Fisetin inhibits TNF-α/NF-κB-induced IL-8 expression by targeting PKCδ in human airway epithelial cells
Keywords: COPD; chronic obstructive pulmonary disease; ELISA; enzyme-linked immunosorbent assay; GM; growth medium; IKK; IκB kinase; PKC; protein kinase C; RT-PCR; reverse transcription-polymerase chain reaction; TNF-α; tumour necrosis factor-α; TNF-R1; TNF-α-r
Chemokines and cytokines on the neuroimmunoaxis: Inner ear neurotrophic cytokines in development and disease. Prospects for repair?
Keywords: BDNF; brain-derived neurotrophic factor; BMP; bone morphogenetic protein(s) (e.g. BMP2, BMP4 etc.); CNS; central nervous system; CCL2; chemokine (C-C) motif ligand 2 (also called MCP1, monocyte chemoattractant protein 1); CCR2; C-C chemokine receptor type
Porcine enterocyte protein Btnl5 negatively regulates NF-kappa B pathway by interfering p65 nuclear translocation
Keywords: Btnl5; butyrophilin-like 5; IECs; intestinal epithelial cells; TRAF2; TNF receptor-associated factor 2; Btn; Butyrophilin; Btnl; butyrophilin-like; Skint; selection and upkeep of intraepithelial T cells; IκB; inhibitory κB; IPTG; isopropy-β-d-thiogalac
The unknown face of IRE1α - Beyond ER stress
Keywords: ER; endoplasmic reticulum; UPR; unfolded protein response; IRE1; inositol requiring kinase enzyme 1; XBP1; x-box binding protein 1; bZIP; basic leucine zipper domain; HAC1; histone acetyl transferase 1; ATF; activating transcription factor; RIDD; regulate
Ubiquitin-proteasome signaling in lung injury
Keywords: AJ; adherens junctions; ALI; acute lung injury; AMPK; adnosine monophosphate activated protein kinase; ARDS; acute respiratory distress syndrome; ATP; adenosine triphosphate; CFTR; cystic fibrosis transmembrane conductance regulator; cIAP; cellular inhibi
SOCS-1 ameliorates smoke inhalation-induced acute lung injury through inhibition of ASK-1 activity and DISC formation
Keywords: SOCS-1; suppressor of cytokine signaling-1; ALI; acute lung injury; ARDS; acute respiratory distress syndrome; SAECs; small airway epithelial cells; GFP; green fluorescent protein; SH2; Src homology 2; ASK-1; apoptosis signal-regulating kinase-1; DISC; de
RACK1/TRAF2 regulation of modulator of apoptosis-1 (MOAP-1)
Keywords: MOAP-1; Ubiquitination; Apoptosis; TRAF2; RACK1; RASSF1A; PKC;
ER stress and cancer: The FOXO forkhead transcription factor link
Keywords: Endoplasmic reticulum; ER stress; Cancer; FOXO; Forkhead transcription factors; Unfolded protein response; AKT; Protein Kinase B; AKT1; Protein Kinase B Alpha; AMPK; AMP-activated protein kinase; ASK1; Apoptosis Signal Regulated Kinase 1; ATF4; Activating
Microglia-derived extracellular vesicles in Alzheimer's Disease: A double-edged sword
Keywords: AD; Alzheimer's Diseases; APP; Amyloid Precursor Protein; Aβ; amyloid; Bcl-2; B-cell lymphoma 2; BBB; blood brain barrier; BMECs; brain microvascular endothelial cells; CNS; central nervous system; CSF; cerebrospinal fluid; EVs; extracellular vesicles;
Sphk1 mediates neuroinflammation and neuronal injury via TRAF2/NF-κB pathways in activated microglia in cerebral ischemia reperfusion
Keywords: Sphk1; Sphingosine kinase 1; S1P; Sphingosine-1-phosphate; IL17; Interleukin-17; IRI; Ischemia reperfusion injury; OGDR; Oxygen-glucose deprivation reperfusion; TNFR2; Tumor necrosis factor receptor2; TRAF2; Tumor necrosis factor receptor-associated facto
Knockdown of TNF receptor-associated factor 2 (TRAF2) modulates in vitro growth of TRAIL-treated prostate cancer cells
Keywords: TRAF2; proliferation; TRAIL; prostate cancer;
TRAF2 of black carp upregulates MAVS-mediated antiviral signaling during innate immune response
Keywords: TRAF2; MAVS; Black carp; Interferon;
MicroRNA-130b transcriptionally regulated by histone H3 deacetylation renders Akt ubiquitination and apoptosis resistance to 6-OHDA
Keywords: DA; dopamine; 6-OHDA; 6-hydroxydopamine; HDAC3; histone deacetylase 3; EPO; erythropoietin; EGF; epidermal growth factor; VEGF; vascular endothelial growth factor; PI3K; phosphatidylinositol-3-kinase; TRAF2; TNF receptor associated factor-2; TAK1; TGF-β-
Oxidative and ER stress-dependent ASK1 activation in steatotic hepatocytes and Kupffer cells sensitizes mice fatty liver to ischemia/reperfusion injury
Keywords: HP; hepatocytes; KC; Kupffer cells; I/R; ischemia-reperfusion; OS; oxidant species; PA; palmitic acid; ND; normal diet; HFD; high fat diet; ANOVA; analysis of variance; CD; control diet; JNK; c-Jun N-terminal kinase-1/2; ASK1; Apoptosis signal-regulating
Cardiac-specific Traf2 overexpression enhances cardiac hypertrophy through activating AKT/GSK3β signaling
Keywords: Traf2; tumor necrosis factor receptor-associated factor 2; TAC; constriction of transverse aortic; GSK3β; AKT/glycogen synthase kinase 3β; LVESD; left ventricle end-systolic diameter; LVEDD; left ventricle end-diastolic diameter; PCR; polymerase chain r
Up-regulation of TRAF2 Suppresses Neuronal Apoptosis after Rat Spinal Cord Injury
Keywords: TRAF2; TNF receptor associated factor 2; CNS; central nervous system; PAGE; polyacrylamide gel electrophoresis; ECL; enhanced chemiluminescence system; BSA; bovine serum albumin; DAB; Diaminobenzidin; NeuN; neuronal nuclei; GAPDH; glyceraldehyde-3-phospha
Verproside inhibits TNF-α-induced MUC5AC expression through suppression of the TNF-α/NF-κB pathway in human airway epithelial cells
Keywords: ChIP; chromatin immunoprecipitation; COPD; chronic obstructive pulmonary disease; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; IKK; IκB kinase; NFκB; nuclear factor kappa B; RIP1; receptor interacting kinase 1; TAK1; transforming growth factor beta-
Effect of curcumin on TNFR2 and TRAF2 in unilateral ureteral obstruction in rats
Keywords: Curcumin; TNFR1; TNFR2; TRAF2; Caspase 8; RIP
MiR-502-5p inhibits IL-1β-induced chondrocyte injury by targeting TRAF2
Keywords: OA; osteoarthritis; miR-502-5p; microRNA-502-5p; IL-1β; interleukin -1 beta; TNFα; tumor necrosis factor alpha; TNFR; tumor necrosis factor receptor; TRAF2; TNF receptor-associated factor 2; ECM; extracellular matrix; MMP-13; matrix metalloproteinase-13
TRAF2 functions as an activator switch in the reactive oxygen species-induced stimulation of MST1
Keywords: Hydrogen peroxide; MST1; Oxidative stress; Reactive oxygen species; TRAF2;
Catalytic-independent inhibition of cIAP1-mediated RIP1 ubiquitination by EGLN3
Keywords: cIAP; cellular inhibitor of apoptosis protein; DFX; Desferrioxamine; DMOG; dimethyl oxalylglycine; EGLN; Caenorhabditis elegans gene egl-9; HA; hemagglutinin; HEK293 cells; human embryonic kidney 293 cells; IB; immunoblotting; IP; immunoprecipitation; HIF
Medicinal herbs Oenanthe javanica (Blume) DC., Casuarina equisetifolia L. and Sorghum bicolor (L.) Moench protect human cells from MPP+ damage via inducing FBXO7 expression
Keywords: FBXO7; Promoter characterization; Medicinal herbs; TRAF2; GATA2; FBXO7; The F-box protein 7; PD; Parkinson's disease; FBP; F-box-containing protein; SCF; Skp1-Cullin1-F-box protein; cIAP1; cellular inhibitor of apoptosis protein 1; TRAF2; TNF receptor-ass
TRAF2 mediates JNK and STAT3 activation in response to IL-1β and IFNγ and facilitates apoptotic death of insulin-producing β-cells
Keywords: Apoptosis; Cytokines; iNOS; STAT3; TRAF2; Type 1 diabetes;
TRAF2-mediated Lys63-linked ubiquitination of DUSP14/MKP6 is essential for its phosphatase activity
Keywords: DUSP14/MKP6; TRAF2; Ubiquitination; T-cell receptor signaling;
TRAF2 multitasking in TNF receptor-induced signaling to NF-κB, MAP kinases and cell death
Keywords: TRAF2; NF-κB; Apoptosis; Necroptosis; TNF;
Molecular and cellular mechanisms linking inflammation to insulin resistance and β-cell dysfunction
Keywords: AMPK; AMP-activated protein kinase; ATM; adipose tissue macrophages; CCL; chemokine (C-C motif) ligand; CCR2; chemokine (C-C motif) receptor 2; CX3CL1; chemokine (C-X3-C motif) ligand 1; CX3CR1; chemokine (C-X3-C motif) receptor; CXCL; CXC chemokine ligan
The inducible E3 ubiquitin ligases SIAH1 and SIAH2 perform critical roles in breast and prostate cancers
Keywords: Cytokine; Estrogen; Sex hormone; SIAH1; SIAH2; ACK1/TNK2; activated CDC42-associated kinase 1; AR; androgen receptor; ATM; ataxia telangiectasia mutated; ATR; ataxia telangiectasia mutated related; BF; biochemical failure; DCC; deleted in colorectal cance
Molecular dynamics and intracellular signaling of the TNF-R1 with the R92Q mutation
Keywords: Tumor necrosis factor; TNF receptor 1; R92Q mutation; Multiple sclerosis; Molecular dynamics; mRNA expression; TRAF2; CASP3; TNF receptor-associated periodic syndrome
Regulation of PGE2 signaling pathways and TNF-alpha signaling pathways on the function of bone marrow-derived dendritic cells and the effects of CP-25
Keywords: PGE2; TNF-alpha; EP4; TRAF2; CP-25; Dendritic cells
Conservation of structure and function in vertebrate c-FLIP proteins despite rapid evolutionary change
Keywords: CARD; caspase-recruitment domain; CASc; Caspase, interleukin-1 β converting enzyme homologs; c-FLIP; cellular FLICE-like inhibitory protein; CHX; cycloheximide; DED; death effector domain; EGFP; enhanced green fluorescent protein; FADD; Fas-associated de
Sinomenine inhibits breast cancer cell invasion and migration by suppressing NF-κB activation mediated by IL-4/miR-324-5p/CUEDC2 axis
Keywords: NF-κB; Sinomenine; Invasion and metastasis; IKK phosphorylation; CUEDC2; NF-κB; nuclear factor kappa-light-chain-enhancer of activated B cells; EMT; epithelial-mesenchymal transition; IκB; inhibitor of NF-κB; IKK; IκB kinase; pIKK; phosphorylated I
Shock/sepsis/trauma/critical careTherapeutic effects of p75 tumor necrosis factor receptor monoclonal antibody on a rat model of traumatic arthritis
Keywords: p75TNFR monoclonal antibody; Traumatic arthritis; Inflammatory factors; Matrix metalloproteinase; TRAF2; NF-κB;
The PP4R1 subunit of protein phosphatase PP4 targets TRAF2 and TRAF6 to mediate inhibition of NF-κB activation
Keywords: CCT; cytoplasmic carboxyl terminal; EBV; Epstein-Barr virus; IFNAR1; interferon- alpha/beta receptor alpha chain; IKK; IκB kinase; IL17R; interleukin-17 receptor; IFλR1; interferon-λ receptor chain 1; Jak3; Janus kinase 3; JNK; cJun kinase; LMP1; l
GSTpi protects against angiotensin II-induced proliferation and migration of vascular smooth muscle cells by preventing signal transducer and activator of transcription 3 activation
Keywords: Ang II; angiotensin II; VSMCs; vascular smooth muscle cells; GSTpi; glutathione S-transferase pi; STAT3; signal transducer and activator of transcription 3; GSH; glutathione; TNF-α; tumor necrosis factor alpha; JNK; c-Jun NH2-terminal kinases; TRAF2; tum
The intricate interplay between RNA viruses and NF-κB
Keywords: ss; single-stranded; ds; double-stranded; HTLV; human T cell leukemia virus; SARS; severe acute respiratory syndrome; IAVs; influenza A viruses; IFN; interferon; IRF3; interferon regulatory factor 3; NF-κB; nuclear factor κB; TLRs; toll-like receptors;
Ischemic insults induce necroptotic cell death in hippocampal neurons through the up-regulation of endogenous RIP3
Keywords: Actb; β-Actin; cIAP; Cellular Inhibitor of Apoptosis Protein; Ctx; Cortex; CYLD; Cylindromatosis; DG; Dentate Gyrus; DISC; Death Inducing Signaling Complex; DR; Death Receptor; FADD; Fas-associated Protein with Death Domain; Gapdh; Glyceraldehyde 3-phosp
Human DExD/H RNA helicases: Emerging roles in stress survival regulation
Keywords: 5â²ppp; 5â² triphosphate; AMD; ARE-mediated mRNA decay; ARE; AU-rich element; ARE-BP; ARE-binding protein; CARD; caspase activation and recruitment domain; CCCP; carbonyl cyanide m-chlorophenyl hydrazone; CDN; cyclic dinucleotide; CRM1; Chromosome Maint
Rotavirus NSP1 inhibits interferon induced non-canonical NFκB activation by interacting with TNF receptor associated factor 2
Keywords: Rotavirus; NSP1; TRAF2; NFκB;
TRAF2 regulates the cytoplasmic/nuclear distribution of TRAF4 and its biological function in breast cancer cells
Keywords: TRAF4; TRAF2; Breast cancer; Nuclear transcription; Apoptosis;