Small molecule scaffolds that disrupt the Rev1-CT/RIR protein-protein interaction
Keywords: سنتز ترجمه; Translesion synthesis; Cancer; Rev1; Protein-protein interaction;
مقالات ISI سنتز ترجمه (ترجمه نشده)
مقالات زیر هنوز به فارسی ترجمه نشده اند.
در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
In vitro lesion bypass by human PrimPol
Keywords: سنتز ترجمه; PrimPol; DNA damage; DNA; Translesion synthesis;
DNA repair mechanisms in response to genotoxicity of warfare agent sulfur mustard
Keywords: سنتز ترجمه; ATM; ataxia telangiectasia mutated; ATR; ataxia telangiectasia and rad3 related; BER; base excision repair; Cdc25; cell division cycle 25; CDKs; cyclin-dependent kinases; CEES; 2-chloroethyl ethyl sulphide; ChK1; checkpoint kinase 1; Chk2; checkpoint kina
Non-canonical processing of DNA photodimers with Bacillus subtilis UV-endonuclease YwjD, 5â²â3â² exonuclease YpcP and low-fidelity DNA polymerases YqjH and YqjW
Keywords: سنتز ترجمه; NER; nucleotide excision repair pathway; UV; ultraviolet light; LF; low fidelity; ds-DNA; double stranded-DNA; PD; pyrimidine dimers; CPD; cyclobutane pyrimidine dimer; 6-4 PD; 6-4 pyrimidine photoproduct; DWI; Dewar isomer; M-C; Mitomycin-C; TLS; transle
ReviewRegulation of DNA damage tolerance in mammalian cells by post-translational modifications of PCNA
Keywords: سنتز ترجمه; TLS; translesion synthesis; PCNA; proliferating cell nuclear antigen; Polη; DNA polymerase eta; HU; hydroxyurea; SUMO; small ubiquitin-related modifier; ISG15; interferon-stimulated gene 15; UV; ultraviolet; MNNG; N-methyl-N'-nitro-N-nitrosoguanidine;
Combined loss of three DNA damage response pathways renders C. elegans intolerant to light
Keywords: سنتز ترجمه; UV-light; C. elegans; Nucleotide excision repair; Translesion synthesis; Alternative end-joining; Daylight; Genome stability; Mutagenesis;
Structural and functional relationships of FAN1
Keywords: سنتز ترجمه; FA, FANC; Fanconi anemia; ICL; interstrand cross-link; DSB; double strand break; TLS; translesion synthesis; HR; homologous recombination; ID2; FANCD2/FANCI; AP; apurinic/apyrimidinic; UBZ; ubiquitin-binding zinc finger; Ub; ubiquitin or ubiquitinated; SA
NGS-based analysis of base-substitution signatures created by yeast DNA polymerase eta and zeta on undamaged and abasic DNA templates in vitro
Keywords: سنتز ترجمه; Translesion synthesis; Error-prone polymerase; Mutagenesis; Mutation signature; DNA damage; DNA repair; Next generation sequencing;
Cell cycle-dependent positive and negative functions of Fun30 chromatin remodeler in DNA damage response
Keywords: سنتز ترجمه; CPT; camptothecin; DDC; DNA damage checkpoint; DDT; DNA damage tolerance; DSB; double stranded DNA break; G6PD; Glucose-6-phosphate dehydrogenase; HR; homologous recombination; HU; hydroxyurea; MMS; methyl methanesulfonate; ssDNA; single stranded DNA; TLS
The DNA-binding box of human SPARTAN contributes to the targeting of Polη to DNA damage sites
Keywords: سنتز ترجمه; SPARTAN; Translesion synthesis; DNA polymerase eta; Damage tolerance;
A role for the base excision repair enzyme NEIL3 in replication-dependent repair of interstrand DNA cross-links derived from psoralen and abasic sites
Keywords: سنتز ترجمه; BCNU; carmustine or 1,3-bis(2-chloroethyl)-1-nitrosourea; BER; base excision repair; CMG helicase; Cdc45-MCM-GINS helicase; NEIL; Nei-like; TLS; translesion synthesis; HR; homologous recombination; NER; nucleotide excision repair; FdT; 2â²-deoxy-2â²-flu
Regulation of DNA repair by non-coding miRNAs
Keywords: سنتز ترجمه; miRNAs; DNA damage; DNA repair; Genomic instability; DSB repair; NER; DSB; double strand break; HR; homologous recombination; NHEJ; non-homologous end joining; NER; nucleotide excision repair; BER; base excision repair; TLS; translesion synthesis; FA; Fan
DNA damage tolerance by recombination: Molecular pathways and DNA structures
Keywords: سنتز ترجمه; DDT; DNA damage tolerance; DDR; DNA damage response; ss; single stranded; DSBs; Double strand breaks; TLS; Translesion Synthesis; PRR; Postreplication repair; HR; Homologous recombination; PCNA; proliferating cell nuclear antigen; SLDs; SUMO-like domains;
Tolerance of lesions in E. coli: Chronological competition between Translesion Synthesis and Damage Avoidance
Keywords: سنتز ترجمه; ssDNA.RecA; single-stranded DNA.RecA filament; TLS; translesion synthesis; DA; damage avoidance; HDGR; homology directed gap repair; DDT; DNA damage tolerance; PRR; post-replication repair; NER; nucleotide excision repair; MMR; mismatch repair; SSB; singl
Pre-steady-state kinetic investigation of bypass of a bulky guanine lesion by human Y-family DNA polymerases
Keywords: سنتز ترجمه; 3-NBA; 3-nitrobenzanthrone; nitroPAH; nitro-polycyclic aromatic hydrocarbon; TA98; Salmonella typhimurium strain TA98; dGC8-N-ABA; N-(2â²-deoxyguanosin-8-yl)-3-aminobenzanthrone; TLS; translesion DNA synthesis; hPolη; human DNA polymerase eta; hPolκ; h
Cancer TARGETases: DSB repair as a pharmacological target
Keywords: سنتز ترجمه; DSB repair; Genome instability; Cancer; Kinases; Helicases; Nucleases; ALT; alternative telomere lengthening; AML; acute myeloid leukemia; A-T; ataxia-telangiectasia; ATM; ataxia-telangiectasia mutated; ATP; adenosine triphosphate; ATR; ataxia-tel
Biophysical characterization of the interaction between FAAP20-UBZ4 domain and Rev1-BRCT domain
Keywords: سنتز ترجمه; FA; Fanconi anemia; ICL; interstrand cross-link; DSB; double-strand break; HR; homologous recombination; MMC; mitomycin C; DEB; diepoxybutane; TLS; translesion synthesis; NER; nucleotide excision repair; FAAP20; Fanconi anemia-associated protein 20; UBZ4;
UV-induced mutations in epidermal cells of mice defective in DNA polymerase η and/or ι
Keywords: سنتز ترجمه; DNA polymerase η; DNA polymerase ι; Translesion synthesis; UV-induced mutagenesis; Xeroderma pigmentosum variant (XP-V);
Roles of translesion synthesis DNA polymerases in the potent mutagenicity of tobacco-specific nitrosamine-derived O2-alkylthymidines in human cells
Keywords: سنتز ترجمه; NNK; 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone; NNN; N'-nitrosonornicotine; O2-Me-dT; O2-methylthymidine; O2-POB-dT; O2-[4-(3-pyridyl)-4-oxobut-1-yl]thymidine; HEK293T; human embryonic kidney 293T; TLS; translesion synthesis; MF; mutation frequency;
Quality control mechanisms in cellular and systemic DNA damage responses
Keywords: سنتز ترجمه; DNA damage; Ageing; Ubiquitin proteasome system; DNA repair; Progeroid syndromes; Genome stability; ARF; adenosine diphosphate ribosylation factor; AT; ataxia telangiectasia; ATM; ataxia telangiectasia mutated; ATP; adenosine triphosphate; BER; base excis
Functional characterization of two SOS-regulated genes involved in mitomycin C resistance in Caulobacter crescentus
Keywords: سنتز ترجمه; Mitomycin C; Endonucleases; dnaE2; imuC; Translesion synthesis; SOS response; Caulobacter crescentus
Aberrant C-terminal domain of polymerase η targets the functional enzyme to the proteosomal degradation pathway
Keywords: سنتز ترجمه; Translesion synthesis; XP-V; Xeroderma pigmentosum variant; Bortezomib; MG132; Ubiquitin/proteasome system; Ultraviolet;
Alternative solutions and new scenarios for translesion DNA synthesis by human PrimPol
Keywords: سنتز ترجمه; PrimPol; DNA primase; DNA polymerase; 8oxoG; Lesion bypass; Translesion synthesis;
Regulation of translesion DNA synthesis: Posttranslational modification of lysine residues in key proteins
Keywords: سنتز ترجمه; TLS; translesion synthesis; PCNA; proliferating cell nuclear antigen; pol; polymerase; PIP; PCNA-interacting peptide; RIR; Rev1-interacting region; UBM; ubiquitin binding motif; UBZ; ubiquitin binding zinc motif; polι; DNA polymerase iota; polη; DNA pol
Contributions of the specialised DNA polymerases to replication of structured DNA
Keywords: سنتز ترجمه; Replication; DNA secondary structures; DNA polymerases; Translesion synthesis; G quadruplex;
Eukaryotic DNA polymerase ζ
Keywords: سنتز ترجمه; DNA polymerase; Mutagenesis; Translesion synthesis; PCNA;
Ethylene oxide and propylene oxide derived N7-alkylguanine adducts are bypassed accurately in vivo
Keywords: سنتز ترجمه; Alkylating agents; N7-alkylguanine adducts; Translesion synthesis;
Ribonucleotide incorporation by yeast DNA polymerase ζ
Keywords: سنتز ترجمه; Ribonucleotides; Mutagenesis; DNA polymerase; Translesion synthesis
Pyrosequencing for the quantitative assessment of 8-oxodG bypass DNA synthesis
Keywords: سنتز ترجمه; ROS; reactive oxygen species; 8-oxodG; 8-oxo-7,8-dihydro-2â²-deoxyguanosine; faPy-G; 2,6-diamino-4-hydroxy-5-formamidopyrimidine; TLS; translesion synthesis; PPi; pyrophosphate; DTT; dithiothreitol; BSA; bovine serum albumin; dNTPs; deoxynucleotides trip
Comparison of the biological effects of MMS and Me-lex, a minor groove methylating agent: Clarifying the role of N3-methyladenine
Keywords: سنتز ترجمه; AP; apurinic/apyrimidinic; apn1apn2; AP endonucleases 1 and 2 defective; BER; base excision repair; 3-mA; N3-methyladenine; 3-m-c3A; 3-methyl-3-deazaadenine; mag1; 3-methyladenine-DNA glycosylase 1 defective; Me-lex; {1-methyl-4-[1-methyl-4-(3-methoxysulf
DNA polymerase POLQ and cellular defense against DNA damage
Keywords: سنتز ترجمه; DNA polymerase; POLQ; Translesion synthesis; Thymine glycol; Abasic site; Genomic instability; Ionizing radiation;
DNA-protein crosslinks processed by nucleotide excision repair and homologous recombination with base and strand preference in E. coli model system
Keywords: سنتز ترجمه; DNA-protein crosslinks; Nucleotide excision repair; MGMT; Dibromoethane; Epibromohydrin; AGT (MGMT); O6-alkylguanine-DNA alkyltransferase; hAGT; human wild type AGT; NER; nucleotide excision repair; TC-NER; transcription-coupled NER; GC-NER; global geno
Discrimination against major groove adducts by Y-family polymerases of the DinB subfamily
Keywords: سنتز ترجمه; pol; polymerase; E. coli; Escherichia coli; S. solfataricus; Sulfolobus solfataricus; fdA; N6-furfuryl-dA; ÉdA; 1,N6-ethenodeoxyadenosine; Human DNA polymerase kappa; Sulfolobus solfataricus Dpo4; Escherichia coli DinB; etheno-dA; Translesion synthesis;
A non-catalytic function of Rev1 in translesion DNA synthesis and mutagenesis is mediated by its stable interaction with Rad5
Keywords: سنتز ترجمه; Translesion synthesis; Rev1; Damage tolerance; DNA damage; Y family DNA polymerase;
Thymidine glycol: the effect on DNA molecular structure and enzymatic processing
Keywords: سنتز ترجمه; Oxidative DNA damage; Thymine glycol repair; Translesion synthesis; Alteration in DNA structure; Tandem (clustered) lesions; Tg; thymine glycol; Tg*; thymidine glycol; Ug; uracil glycol; dUg; 2â²-deoxyuridine glycol; 8-oxoG; 8-oxo-7,8-dihydro-2â²-deoxyg
Measurement of translesion synthesis by fluorescent capillary electrophoresis: 7,8-Dihydro-8-oxodeoxyguanosine bypass modulation by natural products
Keywords: سنتز ترجمه; Translesion synthesis; Capillary electrophoresis; 8-oxodG; Genistein; Myricetin; Indole-3-carbinol
The C-terminal domain of human Rev1 contains independent binding sites for DNA polymerase η and Rev7 subunit of polymerase ζ
Keywords: سنتز ترجمه; TLS; translesion synthesis; Rev1-CT; C-terminal domain of Rev1; RIR; Rev1 interacting region; NMR; nuclear magnetic resonance; TROSY; transverse relaxation optimized spectroscopy; ITC; isothermal titration calorimetry; aa; amino acid; DNA damage tolerance
DNA repair, DNA replication and human disorders: A personal journey
Keywords: سنتز ترجمه; Cockayne syndrome; Schizosaccharomyces pombe; Translesion synthesis; Ultraviolet light; Xeroderma pigmentosum;
Pol kappa partially rescues MMR-dependent cytotoxicity of O6-methylguanine
Keywords: سنتز ترجمه; Translesion synthesis; DNA polymerase κ; O6-methylguanine; RAD 51;
Replication of ribonucleotide-containing DNA templates by yeast replicative polymerases
Keywords: سنتز ترجمه; DNA replication; Ribonucleotides; rNMP bypass; Translesion synthesis;
Timing and spacing of ubiquitin-dependent DNA damage bypass
Keywords: سنتز ترجمه; DNA damage bypass; DNA replication; Mutagenesis; Postreplication repair; Translesion synthesis; Ubiquitin;
HLTF and SHPRH are not essential for PCNA polyubiquitination, survival and somatic hypermutation: Existence of an alternative E3 ligase
Keywords: سنتز ترجمه; PCNA; RAD5; HLTF; SHPRH; Somatic hypermutation; Translesion synthesis
Pre-steady state kinetic studies show that an abasic site is a cognate lesion for the yeast Rev1 protein
Keywords: سنتز ترجمه; dNTP, deoxynucleoside triphosphate; EDTA, ethylenediamine tetraacetic acid; Pol, polymerase; 8-oxoG, 8-oxoguanineDNA replication; DNA repair; DNA polymerase; Translesion synthesis; Mutagenesis
Proteasomal regulation of the mutagenic translesion DNA polymerase, Saccharomyces cerevisiae Rev1
Keywords: سنتز ترجمه; Rev1; Translesion synthesis; DNA damage tolerance; Protein degradation
3-Methyl-3-deazaadenine, a stable isostere of N3-methyl-adenine, is efficiently bypassed by replication in vivo and by transcription in vitro
Keywords: سنتز ترجمه; 3-Methyl-adenine; AP-site; Translesion synthesis; RNA transcription;
Crystal Structure of SUMO-Modified Proliferating Cell Nuclear Antigen
Keywords: سنتز ترجمه; RFC, replication factor C; UbiPCNA, ubiquitin-modified PCNA; SUMOPCNA, SUMO-modified PCNADNA replication; DNA recombination; DNA repair; protein–DNA interactions; translesion synthesis
RAD5a and REV3 function in two alternative pathways of DNA-damage tolerance in Arabidopsis
Keywords: سنتز ترجمه; Plant; DNA-damage tolerance; Translesion synthesis; Error-free bypass; Recombination;
Lesion bypass by S. cerevisiae Pol ζ alone
Keywords: سنتز ترجمه; DNA polymerase zeta; Translesion synthesis; UV photoproducts; Abasic sites;
PCNA ubiquitination-independent activation of polymerase η during somatic hypermutation and DNA damage tolerance
Keywords: سنتز ترجمه; PCNA; Polη; Somatic hypermutation; Translesion synthesis; DNA damage tolerance; Ubiquitination;
Bypass of N2-ethylguanine by human DNA polymerase κ
Keywords: سنتز ترجمه; BSA; bovine serum albumin; DNA pol ι; DNA polymerase ι; N2-ethyl-Gua; N2-ethylguanine; pol; polymerase; Y-family DNA polymerase; Translesion synthesis; Alkylation DNA damage; Metal ion activation; Rapid kinetic analysis; DNA polymerase κ;