β-Lysine discrimination by lysyl-tRNA synthetase
Keywords: Aminoacyl-tRNA synthetase; β-Amino acid; Lysine; Translation; tRNA;
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A deviant genetic code in the green alga-derived plastid in the dinoflagellate Lepidodinium chlorophorum
Keywords: Genetic code; Codon reassignment; tRNA; Plastid; Secondary endosymbiosis; Dinoflagellates
Futile import of tRNAs and proteins into the mitochondrion of Trypanosoma brucei evansi
Keywords: Trypanosoma; tRNA; Protein import; Mitochondrion; Kinetoplast;
Site-specific incorporation of arginine analogs into proteins using arginyl-tRNA synthetase
Keywords: Methylarginine; Arginine analog; Post-translational modification; Histone H3; tRNA; Four-base codon; ArgRS; arginyl-tRNA synthetase; tRNACCCG; tRNA mutant bearing a CCCG four-base anticodon; aa-tRNA; aminoacyl-tRNA; mArg; NG-monomethyl-l-arginine; Cit; l-
Disconnected Interacting Protein 1 binds with high affinity to pre-tRNA and ADAT
Keywords: ADAR; adenosine deaminase that acts on RNA; ADAT; adenosine deaminase that acts on tRNA; AU; analytical ultracentrifugation; DIP1; Disconnected Interacting Protein 1; DIP1-c; longest DIP1 isoform; dsRBD; double-stranded RNA-binding domain; dsRNA; double-s
Large scale expression and purification of recombinant RNA in Escherichia coli
Keywords: Recombinant RNA; Aptamer; Expression plasmid; tRNA; 5S Ribosomal RNA
Functionalized polystyrene supports for solid-phase synthesis of glycyl-, alanyl-, and isoleucyl-RNA conjugates as hydrolysis-resistant mimics of peptidyl-tRNAs
Keywords: Oligonucleotides; RNA-peptide conjugates; Azido nucleoside; Ribosomes; Solid-phase synthesis; tRNA;
Identification of an entire set of tRNA molecules and characterization of cleavage sites of the intron-containing tRNA precursors in acidothermophilic crenarchaeon Sulfolobus tokodaii strain7
Keywords: RT; reverse transcriptase; tRNA; transfer ribonucleic acids; BHB; bulge-helix-bulge; EndA; endonuclease of Archaea; Genome; RT-PCR; Interrupted gene; Splicing endonuclease; Bulge-helix-bulge motif;
An idiosyncratic serine ordering loop in methanogen seryl-tRNA synthetases guides substrates through seryl-tRNASer formation
Keywords: Seryl-tRNA synthetase; Serine ordering loop; tRNASer; Active site mutants; Isothermal titration calorimetry; tRNA; transfer RNA; aaRS; aminoacyl-tRNA synthetase; SerRS; seryl-tRNA synthetase; mMbSerRS; methanogenic-type SerRS from Methanosarcina barkeri;
Recent progress toward understanding the molecular mechanisms that regulate skeletal muscle mass
Keywords: 4E-BP1; 4E binding protein 1; 5â²UTR; 5â² untranslated region; AICAR; 5-aminoimidazole-4-carboxamide riboside; AMP; adenosine monophosphate; AMPK; 5â²-AMP-activated protein kinase; AMPK α1â/â; AMPK α1 subunit knockout; AMPKα1â/âα2â/â; A
Mitochondrial dysfunction and Alzheimer's disease
Keywords: ABAD; amyloid-beta (Aβ) binding alcohol dehydrogenase; AD; Alzheimer's disease; APOE2; Apolipoprotein E epsilon-2 allele; APOE3; Apolipoprotein E epsilon-3 allele; APOE4; Apolipoprotein E epsilon-4 allele; APP; amyloid precursor protein; ATP; Adenosine-5
NMR-Based Substrate Analog Docking to Escherichia coli Peptidyl-tRNA Hydrolase
Keywords: tRNA; fidelity of translation; substrate recognition; enzyme mechanism; enzyme specificityIF, initiation factor; Pth, peptidyl-tRNA hydrolase; 3D, three-dimensional; HSQC, heteronuclear single-quantum coherence; TOCSY, total correlated spectroscopy; NOESY
Condensed E. coli cultures for highly efficient production of proteins containing unnatural amino acids
Keywords: Unnatural amino acid; tRNA; Ubiquitin; Aminoacyl-tRNA synthetaseUAA, unnatural amino acid; Ub, ubiquitin; sfGFP, superfolder green fluorescent protein
Direct interaction between Utp8p and Utp9p contributes to rRNA processing in budding yeast
Keywords: Pre-rRNA process; SSU complex; U3 snoRNA; Utp8; Utp9; tRNA
Discovery and characterization of tRNAIle lysidine synthetase (TilS)
Keywords: tRNA; Lysidine; TilS; AUA codon; Wobble modification; Anticodon
tRNA-nucleotidyltransferases: Highly unusual RNA polymerases with vital functions
Keywords: tRNA; Nucleotidyltransferase; ATP(CTP):tRNA nucleotidyltransferase; CCA-adding enzyme
A bacterial ortholog of class II lysyl-tRNA synthetase activates lysine
Keywords: Aminoacyl-tRNA; Lysyl; tRNA; Translation; GenX; PoxA; YjeA
Arc1p: Anchoring, routing, coordinating
Keywords: Dual localization; Aminoacylation; tRNA; Mitochondria; Metabolism; Saccharomyces cerevisiae
tRNALys3 promoter cassettes that efficiently express RNAi-activating antihepatitis B virus short hairpin RNAs
Keywords: RNAi; tRNA; Promoter; Hepatitis B virus; Expression cassette
Phylogenetic relationships of catostomid fishes (Actinopterygii: Cypriniformes) based on mitochondrial ND4/ND5 gene sequences
Keywords: Catostomidae; Maximum likelihood; RY-coding; Systematics; tRNA
Identification of an avirulent Entamoeba histolytica strain with unique tRNA-linked short tandem repeat markers
Keywords: STR, short tandem repeatAmebiasis; Short tandem repeat; tRNA; Virulence; Symptomatic; Asymptomatic
The T box mechanism: tRNA as a regulatory molecule
Keywords: Transcription attenuation; Antitermination; tRNA; Regulation; Riboswitch
Do all modifications benefit all tRNAs?
Keywords: tRNA; Modification; Degradation; Methylation; Thiolation; Editing
Development of the genetic code: Insights from a fungal codon reassignment
Keywords: Genetic code; Protein synthesis; tRNA; Mistranslation; Codon reassignment; Codon usage; Evolution; Candida
Maternally inherited hearing loss is associated with the novel mitochondrial tRNASer(UCN) 7505T>C mutation in a Han Chinese family
Keywords: Hearing loss; Mitochondrial; tRNA; Mutation; Metabolism; Chinese; Maternally inherited;
Building arks for tRNA: Structure and function of the Arc1p family of non-catalytic tRNA-binding proteins
Keywords: tRNA; Arc1p; Trbp111; p43; p38; p18aaRS, aminoacyl-tRNA synthetase; NLS, nuclear localization signal; NES, nuclear export signal
Complete set of mitochondrial pan-edited mRNAs in Leishmania mexicana amazonensis LV78
Keywords: aa; amino acid; CO; cytochrome c oxidase; Cyb; apocytochrome b; gRNA; guide RNA; kDNA; kinetoplast DNA; mRNA; messenger RNA; MURF; maxicircle unassigned reading frame; ORF; open reading frame; RPS12; ribosomal protein S12; rRNA; ribosomal RNA; tRNA; trans
tRNAs: Cellular barcodes for amino acids
Keywords: aaRS, aminoacyl-tRNA synthetaseAmino acid; Aminoacylation; Protein synthesis; tRNA; Translation
Computational analysis of tRNA identity
Keywords: Proteobacteria; tRNA; Determinant; Logo; Coevolution; Phylogeny
tRNA mitochondrial import in yeast: Mapping of the import determinants in the carrier protein, the precursor of mitochondrial lysyl-tRNA synthetase
Keywords: tRNA; Mitochondrial import; Aminoacyl-tRNA synthetase; Yeast
A population of tRNA-derived small RNAs is actively produced in Trypanosoma cruzi and recruited to specific cytoplasmic granules
Keywords: Trypanosoma cruzi; tRNA; Small non-coding RNAs
Transposon insertion in a serine-specific minor tRNA coding sequence affects intraperitoneal survival of Haemophilus influenzae in the infant rat model
Keywords: O2 radical; Haemophilus; tRNA; Virulence
Slow worm, Anguis fragilis (Reptilia: Anguidae) as a species complex: Genetic structure reveals deep divergences
Keywords: Anguis; Phylogeny; Phylogeography; NADH dehydrogenase subunit 2 (ND2); tRNA; Prolactin receptor (PRLR); Oocyte maturation factor (C-mos); Systematics; Taxonomy
Deciphering synonymous codons in the three domains of life: Co-evolution with specific tRNA modification enzymes
Keywords: tRNA; Translation; Genetic code; Modified nucleosides; Wobble base-pairing; Evolution; Archaea; Bacteria; Eukarya; Mitochondria
Binding of C5 Protein to P RNA Enhances the Rate Constant for Catalysis for P RNA Processing of Pre-tRNAs Lacking a Consensus G(+ 1)/C(+ 72) Pair
Keywords: RNase P, ribonuclease P; Rp-PS, Rp phosphorothioate; Mes, morpholineethanesulfonic acid; EDTA, ethylenediaminetetraacetic acidRNase P; tRNA; ribonucleoprotein; enzyme specificity; catalysis
Positive modulation of RNA polymerase III transcription by ribosomal proteins
Keywords: RNA polymerase III; tRNA; Ribosomal proteins; Saccharomyces cerevisiae; TFIIIE;
High levels of tRNA abundance and alteration of tRNA charging by bortezomib in multiple myeloma
Keywords: MM, multiple myelomaMyeloma; tRNA; Protein translation; Bortezomib
Large-scale movement of functional domains facilitates aminoacylation by human mitochondrial phenylalanyl-tRNA synthetase
Keywords: aaRS, aminoacyl-tRNA synthetase; mtPheRS, mitochondrial phenylalanyl-tRNA synthetase; ABD, anticodon-binding domainAminoacylation; Mitochondrion; Protein synthesis; tRNA; Translation
The complete mitochondrial genome of Watersipora subtorquata (Bryozoa, Gymnolaemata, Ctenostomata) with phylogenetic consideration of Bryozoa
Keywords: atp6 and 8; ATPase subunits 6 and 8; bp; base pair; cox1-3; cytochrome c oxidase subunits I-III; PCGs; protein-coding genes; nCR; non-coding region; cob; cytochrome b; mtDNA; mitochondrial DNA; nad1-6 and 4L; NADH dehydrogenase subunits 1-6 and 4L
On the role of an unusual tRNAGly isoacceptor in Staphylococcus aureus
Keywords: tRNA; Glycine; Isoacceptor; Pseudogene; Staphylococcus
An overview of structural features of DNA and RNA complexes with saffron compounds: Models and antioxidant activity
Keywords: Saffron; DNA; tRNA; Antioxidant; Conformation; FT-IR
Mitochondrial tRNAGlu A14693G variant may modulate the phenotypic manifestation of deafness-associated 12S rRNA A1555G mutation in a Han Chinese family
Keywords: hearing loss; mitochondrial DNA; mutation; modifier; 12S rRNA; tRNA; Chinese family
Recycling of Aborted Ribosomal 50S Subunit-Nascent Chain-tRNA Complexes by the Heat Shock Protein Hsp15
Keywords: nc-tRNA, nascent chain-tRNA; EM, electron microscopy; FSC, Fourier shell correlationHsp15; ribosome; tRNA; heat shock; cryo-EM
The rat mitochondrial Ori L encodes a novel small RNA resembling an ancestral tRNA
Keywords: RNA minihelix; Small RNA; tRNA; Mitochondria; Rat
Leishmania mitochondrial tRNA importers
Keywords: tRNA; Import; Mitochondria; Complex; Leishmania
The mitochondrial ND1 T3308C mutation in a Chinese family with the secondary hypertension
Keywords: Hypertension; Mitochondrial DNA; Mutation; Processing; tRNA; Renal; Modifiers; Chinese;
Take the “A” tail – quality control of ribosomal and transfer RNA
Keywords: RNA quality control; RNA surveillance; tRNA; rRNA; Exosome; TRAMP
Phosphoserine aminoacylation of tRNA bearing an unnatural base anticodon
Keywords: tRNA; Unnatural base pair; Aminoacylation; Synthetase; Phosphoserine; Engineering;
Monitoring Lys-tRNALys phosphatidylglycerol transferase activity
Keywords: Mprf; tRNA; Lysine; Antibiotic;
OXOPAP assay: For selective amplification of aminoacylated tRNAs from total cellular fractions
Keywords: tRNA; Aminoacylation; Editing; Periodate; Synthetase