دانلود مقالات ISI درباره Trpm2 + ترجمه فارسی

بررسی اثربخشی و ریسک درمانهای ضد دیابتی: تجویز داروهای سنتی - تجدیدنظر مکانیکی برای درک نحوه عملکرد آنها

Efficacy and risk profile of anti-diabetic therapies: Conventional vs traditional drugs-A mechanistic revisit to understand their mode of action

Keywords: GLUT; Glucose transporter; T1DM; Type-1 diabetes mellitus; T2DM; Type-2 diabetes mellitus; PKB/Akt; protein kinase B; GSK-3; glycogen synthase kinase-3; PGC-1α; peroxisome proliferator-activated receptor gamma coactivator-1α; FOXO; forkhead box O; VLDL;

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2016 سفارش ترجمه

TRPM2 confers susceptibility to social stress but is essential for behavioral flexibility

Keywords: TRPM2; Stress resiliency; Behavioral inflexibility;

دانلود رایگان متن کامل مقاله ISI 49 صفحه سال انتشار : 2019 سفارش ترجمه

The ADP-ribose reactive NUDIX hydrolase isoforms can modulate HIF-1α in cancer cells

Keywords: ADP-ribose; NUDIX hydrolase; HIF-1α; TRPM2; AMPK;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2018 سفارش ترجمه

Inhibiting the CD38/cADPR pathway protected rats against sepsis associated brain injury

Keywords: CNS; central nervous system; CLP; cecal ligation and puncture; MDA; malondialdehyde; SOD; superoxide dismutase; NAD+; nicotinamide adenine dinucleotide; cADPR; cyclic ADP-ribose; RyRs; ryanodine receptors; TRPM2; transient receptor potential melastatin 2

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

Redox signal-mediated TRPM2 promotes Ang II-induced adipocyte insulin resistance via Ca2+-dependent CaMKII/JNK cascade

Keywords: TRPM2; transient receptor potential melastatin 2; Ang II; angiotensin II; H2O2; hydrogen peroxide; ADPR; ADP-ribose; ACA; N-(p-amylcinnamoyl)anthranilic acid; NAC; N-acetylcysteine; RAS; renin-angiotensin system; AT1R; Ang II type 1 receptor blocker; ACEI

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

Oxytocin release via activation of TRPM2 and CD38 in the hypothalamus during hyperthermia in mice: Implication for autism spectrum disorder

Keywords: CD38; TRPM2; Hyperthermia; Oxytocin; Stress; Autism;

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2018 سفارش ترجمه

TRPM2 mediates mitochondria-dependent apoptosis of melanocytes under oxidative stress

Keywords: ROS; reactive oxygen species; MMP; mitochondrial membrane potential; TRPM2; transient receptor potential cation channel subfamily M member 2; H2O2; hydrogen peroxide; NHMs; Normal human melanocytes; NAC; N-acety-L-cysteine; Ru360; Ruthenium 360; 5-aza-dC;

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2018 سفارش ترجمه

Design, synthesis and biological activities of 2,3-dihydroquinazolin-4(1H)-one derivatives as TRPM2 inhibitors

Keywords: TRPM2; 2,3-Dihydroquinazolin-4(1H)-ones; Inhibitors; SAR; Virtual screening;

دانلود رایگان متن کامل مقاله ISI 44 صفحه سال انتشار : 2018 سفارش ترجمه

TRPM2 contributes to LPC-induced intracellular Ca2+ influx and microglial activation

Keywords: Microglia; TRPM2; LPC; p38MAPK;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Tyrphostin AG-related compounds attenuate H2O2-induced TRPM2-dependent and -independent cellular responses

Keywords: Ca2+; TRPM2; AG-Related compounds; Hydroxyl radical;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Multiple pathways of SIRT6 at the crossroads in the control of longevity, cancer, and cardiovascular diseases

Keywords: ALP; alkaline phosphatase; AMPK; AMP-activated protein kinase; Ang II; angiotensin II; BER; base excision repair; cAMP; cyclic adenosine monophosphate; CDK; cyclin-dependent kinase; CHIP; carboxyl terminus of Hsp70-interacting protein; CLL; chronic lympho

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Activation of a Ca2+-dependent cation conductance with properties of TRPM2 by reactive oxygen species in lens epithelial cells

Keywords: Lens epithelial cells; Ca2+-dependent non-selective cation channel; TRPM2; ROS;

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2017 سفارش ترجمه

Oxidative stress activates the TRPM2-Ca2 +-CaMKII-ROS signaling loop to induce cell death in cancer cells

Keywords: TRPM2; Oxidative stress; Ca2 +;  Reactive oxygen species; CaMKII; Autophagy;

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2017 سفارش ترجمه

Sirtuin-2 mediates male specific neuronal injury following experimental cardiac arrest through activation of TRPM2 ion channels

Keywords: TRPM2; Sirtuin; Cerebral ischemia; Cardiac arrest

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Ca2 + microdomains, NAADP and type 1 ryanodine receptor in cell activation

Keywords: ATP; adenosine triphosphate; ADPR; adenosine diphosphoribose; cADPR; cyclic adenosine diphosphoribose; ER; endoplasmic reticulum; IP3; d-myo-inositol 1,4,5-trisphosphate; IP3R; d-myo-inositol 1,4,5-trisphosphate receptor; NAADP; nicotinic acid adenine din

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Inhibitory effects of Tyrphostin AG-related compounds on oxidative stress-sensitive transient receptor potential channel activation

Keywords: TRPM2; TRPA1; Oxidative stress; AG490; AG555; AG556

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Inhibition of lanthanide nanocrystal-induced inflammasome activation in macrophages by a surface coating peptide through abrogation of ROS production and TRPM2-mediated Ca2+ influx

Keywords: Lanthanide-based nanoparticles (LNs); NLRP3 inflammasome; RE-1 peptide; ROS generation; Ca2+ influx; TRPM2;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

Calcium mobilizing second messengers derived from NAD

Keywords: ADPR; adenosine diphosphoribose; cADPR; cyclic ADP-ribose; [Ca2 +]i; free cytosolic Ca2 + concentration; E(S)R; endoplasmic (sarcoplasmic) reticulum; InsP3; d-myo inositol 1,4,5-trisphosphate; InsP3R; InsP3 receptor; NAADP; nicotinic acid adenine dinucl

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Involvement of TRPM2 in a wide range of inflammatory and neuropathic pain mouse models

Keywords: TRPM2; Inflammatory pain; Neuropathic pain; Pain models; Knockout mice

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Investigation of the effects of distance from sources on apoptosis, oxidative stress and cytosolic calcium accumulation via TRPV1 channels induced by mobile phones and Wi-Fi in breast cancer cells

Keywords: [Ca2 +]i; cytosolic free calcium ion; CAP; capsaicin; DMSO; dimethyl sulfoxide; EGTA; ethylene glycol-bis[2-aminoethyl-ether-N,N,N,N-tetraacetic acid; EMR; electromagnetic radiation; GSM; Global System for Mobile Communications; HBSS; Hank's buffered sal

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Transient receptor potential channel M2 contributes to neointimal hyperplasia in vascular walls

Keywords: α-SMA; α-smooth muscle actin; DHE; dihydroethidium; EdU; 5-ethynyl-2′-deoxyuridine; FBS; fetal bovine serum; HX-XO; hypoxanthine-xanthine oxidase; I/M ratio; ratio of the intimal area to the medial area; KO; knockout; p-Akt; phosphorylated Akt; p-

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Plasma-activated medium induces A549 cell injury via a spiral apoptotic cascade involving the mitochondrial-nuclear network

Keywords: RONS; reactive oxygen and nitrogen species; PAM; plasma-activated medium; NOx; nitrate/nitrite; DMEM; Dulbecco's modified Eagle's medium; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; LDH; lactate dehydrogenase; CHOP; C/EBP homolo

دانلود رایگان متن کامل مقاله ISI 62 صفحه سال انتشار : 2015 سفارش ترجمه

Inhibitory effects of AG490 on H2O2-induced TRPM2-mediated Ca2+ entry

Keywords: TRPM2; TRPA1; Janus kinase 2; AG490; Oxidative stress;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Expression and regulation of transient receptor potential cation channel, subfamily M, member 2 (TRPM2) in human endometrium

Keywords: Estrogen; TRPM2; Human endometrium;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Role of TRPM2 and TRPV1 cation channels in cellular responses to radiation-induced DNA damage

Keywords: ADPR; adenine 5′-diphosphoribose; 2-APB; 2-aminoethoxydiphenyl borate; ATM; ataxia telangiectasia mutated; 53BP1; tumor suppressor p53-binding protein 1; CAP; capsaicin; CPZ; capsazepine; DPQ; 3,4-dihydro-5-[4-(1-piperidinyl)butoxy]-1(2H)-isoquinolinone

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

TRPM2 channel activation following in vitro ischemia contributes to male hippocampal cell death

Keywords: TRPM2; Ischemia; Neuroprotection; Excitotoxicity; Hippocampus

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

TRPM2 channel protective properties of N-acetylcysteine on cytosolic glutathione depletion dependent oxidative stress and Ca2+ influx in rat dorsal root ganglion

Keywords: 2-APB; 2-aminoethyl diphenylborinate; ADPR; adenosine diphosphatase ribose; DRG; dorsal root ganglion; LP; lipid peroxidation; NMDG+; N-methyl-D-glucamine; ROS; reactive oxygen species; TRP; transient receptor potential; TRPM2; melastatin-like transient r

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

The juvenile myoclonic epilepsy-related protein EFHC1 interacts with the redox-sensitive TRPM2 channel linked to cell death

Keywords: Epilepsy; TRP channels; TRPM2; Cell death; Oxidative stress

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Sulfur mustard primes human neutrophils for increased degranulation and stimulates cytokine release via TRPM2/p38 MAPK signaling

Keywords: Sulfur mustard; Neutrophil; Priming; Cytokine release; TRPM2; p38 MAPK

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Melatonin modulates apoptosis and TRPM2 channels in transfected cells activated by oxidative stress

Keywords: 2-APB; 2-aminoethoxydiphenyl borate; ADPR; ADP-ribose; CHO; Chinese Hamster Ovary; DMSO; dimethyl sulfoxide; DRG; dorsal root ganglion; GFP; green fluorescent protein; GSH; glutathione; GSH-Px; glutathione peroxidase; LP; lipid peroxidation; PARP; poly(AD

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Comparing ion conductance recordings of synthetic lipid bilayers with cell membranes containing TRP channels

Keywords: TRP channel; TRPA1; TRPM2; TRPM8; Lipid pore; Phase transition;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Roles of TRPM2 in oxidative stress

Keywords: TRP channels; Oxidative stress; Ca2+ signaling; Cell death; TRPM2

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Gene variation of the transient receptor potential cation channel, subfamily M, member 2 (TRPM2) and type 2 diabetes mellitus: A case–control study

Keywords: TRPM2; Tag-SNPs; Type 2 diabetes mellitus

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2010 سفارش ترجمه

Stimulation of TRPC5 cationic channels by low micromolar concentrations of lead ions (Pb2+)

Keywords: Calcium channel; Transient receptor potential; Lead; TRPC5; TRPM2; TRPM3;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

TRPM7 and TRPM2—Candidate susceptibility genes for Western Pacific ALS and PD?

Keywords: TRPM7; TRPM2; Western Pacific ALS; Parkinsonism Dementia; Oxidative stress; Neurodegeneration; Ca2+ and Mg2+ homeostasis; Mitochondrial dysfunction; Microglial activation

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2007 سفارش ترجمه

Intracellular-produced hydroxyl radical mediates H2O2-induced Ca2+ influx and cell death in rat β-cell line RIN-5F

Keywords: Hydroxyl radical; Hydrogen peroxide; TRPM2; Calcium; Cell death; RIN-5F

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2006 سفارش ترجمه

Determination of intracellular concentrations of the TRPM2 agonist ADP-ribose by reversed-phase HPLC

Keywords: ADP-ribose; TRPM2; KCa channels; HPLC; Calcium signaling; Solid phase extraction;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2005 سفارش ترجمه

Characterization of human and mouse TRPM2 genes: Identification of a novel N-terminal truncated protein specifically expressed in human striatum

Keywords: TRPM2; TRPC7; LTRPC2; Calcium channel; Transcript; Striatum; Bipolar disorder;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2005 سفارش ترجمه