Keywords: Thioredoxins; Cholestasis; Oxidative stress; Cholangiocyte; ALT; Alanine aminotransferase; BDL; Bile duct ligation; GCLC; Gamma-glutamylcysteine; GSH; Reduced glutathione; GST; Glutathione S-Transferase; HO-1; Heme Oxygenase 1; 4-HNE; 4-hydroxy-2-nonenal;
مقالات ISI (ترجمه نشده)
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Keywords: Carcinogenesis; Chemoprevention; Chemotherapy; Oxidative stress; Nrf2; Phytochemicals; AKT; protein kinase B; AMPK; AMP-activated protein kinase; ARE; antioxidant response element; ATF-2; activating transcriptional factor; BBN; N-butyl-N-(4-hydroxybutyl)n
Keywords: ICP-MS; inductively coupled argon plasma emission spectroscopy; Ig; immunoglobulin; MW; molecular weight; OVA; ovalbumin; TMB; 3, 3', 5, 5'-tetramethyl benzidine; TrxR; thioredoxin reductase; T-TBS; Tween-Tris buffered saline; WB; whole blood; Newborn
Keywords: Selenophosphate synthetase; Selenium delivery protein; Selenopersulfide; Selenoprotein biosynthesis; Selenide; Selenium metabolism; O2-; superoxide radical anion; CysDS; cysteine desulfurase; EcSPS; Escherichia coli SPS; Grx; glutaredoxin; GSH; glutathi
Keywords: RA; rheumatoid arthritis; SLE; systemic lupus erythematosus; ROS; reactive oxygen species; RNS; reactive nitrogen species; Î2â
â; superoxide radical; H2O2; hydrogen peroxide; â¢OH; hydroxyl radical; HOCl; hypochlorous acid; NO; nitric oxide; ONOO-; p
Keywords: Synthesis; Curcumin hybrids; Anticancer activity; TrxR;
Keywords: Organic arsenicals; TrxR; Oxidative stress; Mitochondrial dysfunction;
Keywords: AF; S-triethyl phosphine gold(I)-2,3,4,6-tetra-O-acetyl-1-thio-β-D-glucopyranoside (Auranofin); AP-1; activator protein 1; ARE; antioxidant response element; ASK1; apoptosis signal-regulating kinase 1; [Au(dppe)2]Cl; [bis(diphenylphosphino)ethane]gold(I)
Keywords: AI; adequate intake; Cys; cysteine; DNMT, DIO; iodothyronine deiodinase; DNA; methyltransferase; EAR; estimated average requirement; HDAC; histone deacetylase; HSP; heat shock protein; HRM; high-resolution metabolomics; ICP-MS; inductively coupled plasma
Keywords: Heavy metal; Apoptosis; Neurodegeneration; Acetylcholinesterase; Seleno-protein; H2S; Hydrogen sulfide; MeHg; methylmercury; AChE; acetylcholinesterase; GPx; Glutathione peroxidases; TrxR; thioredoxin reductases; GSH; glutathione; TUNEL; Terminal-deoxynuc
Keywords: HNC; head and neck cancer; GSH; glutathione; TrxR; thioredoxin reductase; Nrf2; nuclear factor erythroid-derived 2-like 2 (NFE2L2); Keap 1; Kelch-like ECH-associated protein 1; ARE; antioxidant response element; HO-1; heme oxygenase 1 (HMOX1); ROS; reacti
Keywords: Naphthazarin derivatives; 2-Methylnaphthazarin; Thioredoxin reductase; Reactive oxygen species; Oxidative stress; Apoptosis; BSO; l-buthionine-(S,R)-sulfoximine; DCFH-DA; 2â², 7â²-dichlorfluorescein diacetate; DHE; dihydroethidium; GR; glutathione reduc
Keywords: Baicalin; Baicalein; Flavonoids; Chemoprevention; Inflammatory diseases; 6-OHDA; 6-hydroxydopamine; 12-LOX; 12-lipoxygenase; AIDS; acquired immunodeficiency disorder syndrome; AhR; aryl hydrocarbon receptor; AIH; autoimmune hepatitis; AICAR; 5-aminoimidaz
Keywords: â¢OH; hydroxyl radical; 2,2-BP; 2,2-bipyridyl; ABC; ATP-binding cassette; AIF; apoptosis-inducing factor; AMPK; AMP-activated protein kinase; AMPKK; AMPK kinase; ANT; adenine nucleotide translocase; AP-1; activator protein 1; Apaf-1; protease activating
Keywords: FBE; Actin free barbed ends; ASC; Apoptosis-associated Speck protein with CARD domain; CT; citrate transporter; ME; cytosolic NADP-dependent malic enzyme; DCF-DA; 2;7-dihydrodichloro-fluorescein diacetate; FAK; focal adhesion kinase; ER; endoplasmic retic
Keywords: Oxidative stress; Ebselen; Glutathione peroxidase; Selenoprotein P; Diabetes; Differentiation; ApoER-2; apolipoprotein E receptor 2; C/EBP; CCAAT/enhancer binding protein; DIO; iodothyronine deiodinase; FoxO1a; forkhead box class O1a; GPx; glutathione per
Keywords: Prx; Peroxiredoxin; Trx; Thioredoxin; TrxR; Thioredoxin Reductase; DCM; Diabetic cardiomyopathy; STZ; Streptozotocin; QUE; Quercetin; HW; Heart weight; BW; Body weight; ECG; Electrocardiography; MABP; Mean arterial blood pressure; LVSP; Left ventricular s
Keywords: Trx; thioredoxin; TrxR; thioredoxin reductase; TrxR1; thioredoxin reductase 1; Sec or U; selenocysteine; Cys or C; cysteine; Trp or W; tryptophan; Ser or S; serine; Asn or N; asparagine; Ala or A; alanine; Gly or G; glycine; juglone; 5-hydroxy-1,4-naphtho
Keywords: ROS; reactive oxygen species; GSH; reduced glutathione; GSSG; oxidised glutathione; ER; endoplasmic reticulum; ɣ-GCS; gamma glutamylcysteine synthetase; GGT; ɣ-L-glutamyl transpeptidase; DP; dipeptidase; GR; glutathione reductase; GST; glutathione S-tra
Keywords: DCGI; Drug Controller of India; FSH; follicle stimulating hormone; FDA; Food and Drug Administration; Hg; mercury; LH; luteinizing hormone; MeHg; methyl mercury; ppm; parts per million; TrXR; thioredoxin-reductase; WHO; World Health Organisation; Atomic a
Keywords: Antioxidant; Oxidative stress; Redox; Tumor; Cancer therapy; Akt; protein kinase B; AMPK; 5â²-adenosine monophosphate-activated protein kinase; ATM; ataxia telangiectasia-mutated; DR5; death receptor 5; EC; epicatechin; ECG; epicatechin-3-gallate; EGC; e
Keywords: CCA; Common carotid artery; cer; Cerebellum; CNS; Central nervous system; ELISA; Enzyme-linked immunosorbent assay; Grx; Glutaredoxins; hip; Hippocampus; P7; Postnatal day 7; PA; Perinatal asphyxia; PBS; Phosphate buffer saline; Prx; Peroxiredoxins; ROS;
Keywords: AML; acute myeloid leukemia; APL; acute promyelocytic leukemia; ATRA; all-trans retinoic acid; BHA; butylated hydroxyanisole; C/EBP; CCAAT/enhancer binding proteins; CREB; cyclic AMP response element-binding proteins; CSF; cerebrospinal fluid; DUOX; dual
Keywords: Benzoselenazole-stilbene hybrids; Antiproliferative activity; Apoptosis; G2/M cell cycle arrest; TrxR; ROS;
Keywords: BSA; bovine serum albumin; DCFH-DA; 2â²,7â²-dichlorofluorescin diacetate; GPx; glutathione peroxidase; GR; glutathione reductase; GSH; glutathione; GST; glutathione S-transferase; HCC; hepatocellular carcinoma; IPC; intraperitoneal chemotherapy; NADPH;
Keywords: Thioredoxin reductase; Thioredoxin; Ambroxol; Reactive oxidative species; 5-IAF; 5-(iodoacetamido)fluorescein; ABX; trans-4-(2-amino-3,5-dibromobenzylamino)-cyclohexanol, ambroxol; DCFH-DA; 2â²-7â²-dichlorodihydrofluorescein diacetate; DCF; 2â²,7â²-di
Keywords: AP-1; Activator protein-1; APE; Apurinic/apyrimidinic endonuclease; ARE; Antioxidant response element; ChIP; Chromatin immunoprecipitation; CRE; cAMP response element; CREB; CRE binding protein; Egr-1; Early growth response factor-1; EMSA; Electrophoretic
Keywords: Antioxidant gene therapy; Brain ischemia; Neurodegenerative disorders; Oxidative stress; Virus-mediated gene delivery; ROS; ÎΨm; mitochondrial membrane potential; 3-NP; 3-nitropropionic acid; 6-OHDA; 6-hydroxydopamine; AADC; aromatic-l-amino decarboxyla
Redox regulation by reversible protein S-thiolation in Gram-positive bacteria
Keywords: Ac; acetyl; AcCys; acetyl cysteine; AhpE; membrane-associated peroxidase; AldA; aldehyde dehydrogenase A; Bca; BSH S-conjugate amidase; Brx; bacilliredoxin; BSH; bacillithiol; BshA; glycosyltransferase for GlcNAc-Mal biosynthesis; BshB; deacetylase produc
Babesia microti thioredoxin 3 is an effective antioxidant and involved in the response to antiprotozoal drugs
Keywords: Trx; thioredoxin; TrxR; thioredoxin reductase; NADPH; nicotinamide adenine dinucleotide phosphate; BmTrx3; B. microti thioredoxin 3; RACE; rapid amplification of cDNA ends; IFA; Immunofluorescence assay; IPTG; Isopropyl β-d-1-Thiogalactopyranoside; PBS;
Proteins involved in the antioxidant and inflammatory response in rutin-treated human skin fibroblasts exposed to UVA or UVB irradiation
Keywords: AKT; protein kinase B; AMBIC; ammonium bicarbonate; Bad; Bcl-2-associated death promoter; Bax; bcl-2-like protein 4; Bcl-2; B-cell lymphoma 2 protein; Bcl-XL; B-cell lymphoma-extra-large protein; CCAR2; cell cycle/apoptosis regulator protein 2; DFF; DNA f
Butaselen prevents hepatocarcinogenesis and progression through inhibiting thioredoxin reductase activity
Keywords: HCC; hepatocellular carcinoma; IκBs; NF-κB inhibitory proteins; TrxR; thioredoxin reductase; Trx; thioredoxin; BS; butaselen; NAC; N-acetyl-L-cysteine; DEN; diethylnitrosamine; GPC3; glypican-3; COX-2; cyclooxygenase-2; iNOS; inducible nitric oxide synt
Hepatic cell sheets engineered from human mesenchymal stem cells with a single small molecule compound IC-2 ameliorate acute liver injury in mice
Keywords: Hepatic cell sheets; Mesenchymal stem cells; Liver regeneration; Wnt/β-catenin signal inhibitor; Acute liver failure; BM-MSCs; bone marrow-derived mesenchymal stem cells; NF-κB; nuclear factor-kappa B; IL-6; interleukin-6; STAT-3; Signal Tranducer and A
Mapping the phenotypic repertoire of the cytoplasmic 2-Cys peroxiredoxin - Thioredoxin system. 1. Understanding commonalities and differences among cell types
Keywords: ASK1; apoptosis signal-regulating kinase 1; Cat; catalase; GSH; glutathione; GPx1; glutathione peroxidase 1; Grx; glutaredoxin; KEAP1; Kelch-like ECH-associated protein 1; NRF2; nuclear factor erythroid 2-related factor 2; Prx; typical 2-Cys peroxiredoxin
Safety profile of AZT derivatives: Organoselenium moieties confer different cytotoxic responses in fresh human erythrocytes during in vitro exposures
Keywords: AZT; 3â²-deoxythymidine or zidovudine; SZ1; 5â²-(4-chlorophenylseleno)zidovudine; SZ2; 5â²-(Phenylseleno)zidovudine; SZ3; 5â²-(4-methylphenylseleno)zidovudine; Se; Selenium; HIV; human immunodeficiency virus; AIDS; Acquired immunodeficiency syndrome;
A pivotal role for NF-κB in the macrophage inflammatory response to the myeloperoxidase oxidant hypothiocyanous acid
Keywords: Macrophage; Atherosclerosis; Myeloperoxidase; Oxidative stress; Inflammation; Cytokine; BSA; bovine serum albumin; CCCP; carbonyl cyanide m-chlorophenyl hydrazone; HOCl; hypochlorous acid; HOSCN; hypothiocyanous acid; HUVEC; human umbilical vein endotheli
Selenocysteine in mammalian thioredoxin reductase and application of ebselen as a therapeutic
Keywords: Trx; thioredoxin; TrxR; thioredoxin reductase; Sec; selenocysteine; ROS; reactive oxygen species; RNR; ribonucleotide reductase; GSH; glutathione; GR; glutathione reductase; Grx; glutaredoxin; GPx; glutathione peroxidase; Msr; methionine-R-sulfoxide reduc
Control of the NADPH supply and GSH recycling for oxidative stress management in hepatoma and liver mitochondria
Keywords: 2-OG; 2-oxoglutarate; CHP; cumene hydroperoxide; Glu; glutamate; GDH; glutamate dehydrogenase; GPx-1; glutathione peroxidase 1; GPx-4; glutathione peroxidase 4; GR; glutathione reductase; GSH; reduced glutathione; GSSG; oxidized glutathione; GST; GSH-S-tr
Brazil nut improves the oxidative metabolism of superoxide-hydrogen peroxide chemically-imbalanced human fibroblasts in a nutrigenomic manner
Keywords: Val16Ala-SOD2 polymorphism; Selenium; Seleno-L-methionine; Paraquat; MnTBAP; Nutrigenomic effect; Ala; alanine; BN; Brazil nut; BNs; Brazil nuts; BNAE; Brazil nut aqueous extract; CAT; catalase (E.C. 1.11.1.6); DCFH-DA; 2â²,7â²-Dichlorodihydrofluorescei
N-acetylcysteine improves the quality of red blood cells stored for transfusion
Keywords: Packed red blood cells; N-acetylcysteine; Oxidative stress; Glutathione; Peroxiredoxin-2; Thiol homeostasis; RBC; red blood cells; NAC; N-acetylcysteine; Prx2; peroxiredoxin-2; GSH; reduced glutathione; GSSG; oxidized glutathione; Gpx; glutathione peroxid
Shikonin inhibits gefitinib-resistant non-small cell lung cancer by inhibiting TrxR and activating the EGFR proteasomal degradation pathway
Keywords: NSCLC; non-small cell lung cancer cell; ROS; reactive oxygen species; EGFR; epidermal growth factor receptor; T790M; a substitution mutation of threonine with methionine at position 790 of EGFR; TrxR; thioredoxin reductases; MTT; 3-(4,5-dimetrylthiazol)-2
Synergism between thioredoxin reductase inhibitor ethaselen and sodium selenite in inhibiting proliferation and inducing death of human non-small cell lung cancer cells
Keywords: Thioredoxin reductase (TrxR); Sodium selenite; Apoptosis; Necrosis; Autophagy; Ref-1/AP-1 pathway; Trx; thioredoxin; TrxR; thioredoxin reductase; NSCLC; non-small cell lung cancer; BBSKE; ethaselen; Ref-1; redox factor 1; AP-1; activator protein-1; GSH; g
Polyamine- and NADPH-dependent generation of ROS during Helicobacter pylori infection: A blessing in disguise
Keywords: 8-OHdG; 8-hydroxy-2-deoxyguanosine; ABL1; ABL proto-oncogene 1; AhpC; alkyl hydroperoxide reductase; AKT1; V-Akt murine thymoma viral oncogene homolog 1; APEX1; endonuclease apurinic/apyrimidinic endodeoxyribonuclease 1; ARG1; arginase 1; ARG2; arginase 2
Modulation of signaling mechanisms in the heart by thioredoxin 1
Keywords: Akt; protein kinase B; AMPK; Adenosine Monophosphate-activated Protein Kinase; Ang-II; Angiotensin-II; AP1; Activator protein 1 (AP-1); ASK1; Apoptosis Signal-regulating kinase; Atg4; Autophagy related-4; ATP; Adenosine Triphosphate; CDDP; cis-diammine-di
Brevetoxin-2, is a unique inhibitor of the C-terminal redox center of mammalian thioredoxin reductase-1
Keywords: Karenia brevis; Brevetoxin; Thioredoxin; Thioredoxin reductase; BSA; bovine serum albumin; DTNB; Ellman's reagent: 5,5â²-dithio-bis-(2-nitrobenzoic acid); ESI; electrospray ionization; FAD; flavin adenine dinucleotide; FT-ICR; Fourier transform ion cyclo
Non-linear impact of glutathione depletion on C. elegans life span and stress resistance
Keywords: BCA; bicinchoninic acid; C. elegans; Caenorhabditis elegans; CTL; catalase; DAF-16; abnormal dauer formation 16; DEM; diethyl maleate; DMSO; dimethyl sulfoxide; DTNB; 5,5'-dithiobis-(2-nitrobenzoic acid); E. coli; Escherichia coli; EGL; egg laying defecti
Methylglyoxal-induced AMPK activation leads to autophagic degradation of thioredoxin 1 and glyoxalase 2 in HT22 nerve cells
Keywords: ACC; acetyl co-enzyme A carboxylase; AGE; advanced glycation end products; AMPK; 5â² AMP-activated protein kinase; ATG; autophagy related; BAF; bafilomycin; CQ; chloroquine; DMEM; high-glucose Dulbecco's modified Eagle medium; Glo; glyoxalase; GSH; gluta
Superoxide-hydrogen peroxide genetic imbalance modulates differentially the oxidative metabolism on human peripheral blood mononuclear cells exposed to seleno-L-methionine
Keywords: Val16Ala-MnSOD gene polymorphism; Selenium; Selenoproteins; Thioredoxin reductase; Immune cell; Ala; alanine; CAT; catalase E.C. 1.11.1.6; DTNB; 5,5â³-Dithiobis(2-nitrobenzoic acid); Fe2+; ferrous iron; GPx; glutathione peroxidase EC 1.11.1.9; NO; nitric
Alkynyl gold(I) phosphane complexes: Evaluation of structure-activity-relationships for the phosphane ligands, effects on key signaling proteins and preliminary in-vivo studies with a nanoformulated complex
Keywords: DFT; density functional theory; ERK; extracellular signal related kinase; FAK; focal adhesion kinase; GSK; glycogen synthase kinase; HSP; heat shock protein; MAPK; mitogen activated protein kinase; TOR; target of rapamycin; TrxR; thioredoxin reductase; Al
Synergistic inhibition of sunitinib and ethaselen against human colorectal cancer cells proliferation
Keywords: TKI; tyrosine kinase inhibitor; VEGFRs; vascular endothelial growth factor receptors; PDGFRs; platelet-derived growth factor receptors; NSCLC; non-small cell lung cancer; Trx; thioredoxin; TrxR; thioredoxin reductase; BBSKE; ethaselen; ROS; reactive oxyge