دانلود مقالات ISI درباره Trxr + ترجمه فارسی

Ruthenium(II) p-cymene complexes of naphthoquinone derivatives as antitumor agents: A structure−activity relationship study

Keywords: Ru(II) complex; Naphthoquinone; Cytotoxicity; Hypoxia; Apoptosis; Lap; lapachol; Plum; plumbagin; Law; lawsone; Jug; juglone; PTA; 1,3,5-triaza-7-phosphaadamantane; LDH; Lactate Dehydrogenase; PBS; phosphate-buffered saline; IC50; half maximal inhibitory

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

X-ray structures of thioredoxin and thioredoxin reductase from Entamoeba histolytica and prevailing hypothesis of the mechanism of Auranofin action

Keywords: Trx; thioredoxin; TrxR; thioredoxin reductase; TGR; thioredoxin-glutathione reductase; DTNB; 5,5′-dithiobis(2-nitrobenzoic acid); TNB; thionitrobenzoate; Human amebiasis; Entamoeba histolytica; Auranofin; Thioredoxin reductase; Thioredoxin; X-ray struct

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Epigallocatechin-3-gallate enhances key enzymatic activities of hepatic thioredoxin and glutathione systems in selenium-optimal mice but activates hepatic Nrf2 responses in selenium-deficient mice

Keywords: ALT; alanine aminotransferase; AST; aspartate aminotransferase; BSO; buthionine sulfoximine; CDNB; 1-chloro-2, 4-dinitrobenzene; ECL; enhanced chemiluminescense; EDTA; ethylene diamine tetraacetic acid; EGCG; epigallocatechin-3-gallate; FoxO; Forkhead box

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Perturbation of redox balance after thioredoxin reductase deficiency interrupts autophagy-lysosomal degradation pathway and enhances cell death in nutritionally stressed SH-SY5Y cells

Keywords: 3-MA; 3-Methyl adenine; AL; autolysosome; AP; autophagosome; ATG; autophagy related; Au; auranofin; Baf A1; bafilomycin A1; CCK-8; cell counting kit-8; CQ; chloroquine; DMEM; Dulbecco's modified eagle medium; DMSO; dimethyl sulfoxide; DTNB; 5,5'-Dithi

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2016 سفارش ترجمه

Thioredoxin-mimetic peptides as catalysts of S-denitrosylation and anti-nitrosative stress agents

Keywords: CysNO; S-nitrosocysteine; SNO; S-nitrosothiol; Trx; thioredoxin; TrxR; thioredoxin reductase; TXM; thioredoxin mimetic; Prx; peroxiredoxin; CB3; Ac-Cys-Pro-Cys-amide; CB4; Ac-Cys-Gly-Pro-Cys-amide; Nitrosative stress; Denitrosylation; Thioredoxin mimetic

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Molecular profiling and functional insights of rock bream (Oplegnathus fasciatus) thioredoxin reductase 3-like molecule: investigation of its transcriptional modulation in response to live pathogen stress

Keywords: Trx; thioredoxin; TrxR; thioredoxin reductase; PCR; polymerase chain reaction; qPCR; quantitative real time PCR; NADPH; nicotinamide adenine dinucleotide phosphate; ROS; reactive oxygen species; NADH; nicotinamide adenine dinucleotide; FAD; flavin adenine

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Redox regulation of metabolic and signaling pathways by thioredoxin and glutaredoxin in NOS-3 overexpressing hepatoblastoma cells

Keywords: ACO; aconitase; ASK1; apoptosis signal-regulating kinase 1; Bcl-2; B-cell lymphoma 2; CaM; calmodulin; CD95; cluster of differentiation 95; DTNB; 5,5-dithio-bis-2-nitrobenzoic acid; ELISA; enzyme-linked immunosorbent assay; GAPDH; glyceraldehyde-3-phospha

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Mechanistic characterization of the thioredoxin system in the removal of hydrogen peroxide

Keywords: Grx2; glutaredoxin; Prx; peroxiredoxin; ROS; reactive oxygen species; SeCys; selenocysteine; Trx; thioredoxin; TrxR; thioredoxin reductase; Mathematical model; Enzyme kinetics; Redox biology; Hydrogen peroxide; Thioredoxin system; ROS scavenging;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

Reversible oxidation of PRL family protein-tyrosine phosphatases

Keywords: Cys; cysteine; DTNB; 5,5′-dithiobis-2-nitrobenzoic acid; DTT; dithiothreitol; GSH; glutathione; IPTG; isopropyl-β-d-thiogalactopyranoside; MKP; MAP kinase phosphatase; NADPH; nicotinamide adenine dinucleotide phosphate; NEM; N-ethlymaleimide; PIP3; pho

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

The effect of a minor constituent of essential oil from Citrus aurantium: The role of β-myrcene in preventing peptic ulcer disease

Keywords: NSAIDs; non-steroidal anti-inflammatory drugs; I/R; ischaemia-reperfusion injury; GPx; glutathione peroxidase; SOD; superoxide dismutase; GR; glutathione reductase; PGE2; prostaglandin E2; ROS; reactive oxygen species; NEM; N-ethylmaleimide; l-NAME; N-n

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Strategy to enhance the anticancer efficacy of X-ray radiotherapy in melanoma cells by platinum complexes, the role of ROS-mediated signaling pathways

Keywords: Pt; platinum; Trx; thioredoxin; TrxR; thioredoxin reductase; ROS; reactive oxygen species; SER; sensitivity enhancement ratio; p-PIP; 2-phenyl-1H-imidazo [4, 5-f] [1, 10] phenanthroline; p-NPIP; 2-(4-nitrophenyl)-1H- imidazo [4, 5-f] [1, 10] phenanthrol

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Kinetic and structural characterization of a typical two-cysteine peroxiredoxin from Leptospira interrogans exhibiting redox sensitivity

Keywords: TRXR; thioredoxin reductase; TRX; thioredoxin; HEDS; 2-hydroxyethyl disulfide; 2-CysPrx; two-cysteine peroxiredoxin; AhpC; alkylhydroperoxide reductase C; DTT; dithiothreitol; t-bOOH; tert-butylhydroperoxide; CP; peroxidatic Cys; CR; resolving Cys; Leptos

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Simvastatin inhibits the core promoter of the TXNRD1 gene and lowers cellular TrxR activity in HepG2 cells

Keywords: TrxR; thioredoxin reductase; TXNRD1; human gene for TrxR1; SIM; simvastatin; FLU; fluvastatin; ATV; atorvastatin; ARE; antioxidant responsive element; Nrf2; NF-E2-related factor-2; Simvastatin; Fluvastatin; HMGCoA reductase inhibitor; Thioredoxin reductas

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Development of an in vitro skin sensitization test based on ROS production in THP-1 cells

Keywords: BH; 1-bromohaxane; BKC; benzalkonium chloride; CB; chlorobenzene; CM-H2DCFDA; 5-(and 6-)-chloromethyl-2′, 7′-dichlorodihydrofluorescein diacetate, acetyl ester; DCs; dendritic cells; DCV5; concentration showing 5% decrease of cell viability relative

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Nrf2 deficiency induces oxidative stress and promotes RANKL-induced osteoclast differentiation

Keywords: OC; osteoclast; M-CSF; macrophage colony-stimulating factor; NF-κB; nuclear factor-κB; RANKL; receptor activator of NF-κB ligand; TNF; tumor necrosis factor; TRAF; TNF receptor-associated factor; MAPK; mitogen-activated protein kinase; JNK; c-Jun N-ter

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Protein disulfide isomerase and glutathione are alternative substrates in the one Cys catalytic cycle of glutathione peroxidase 7

Keywords: CysGPxs; subfamily of glutathione peroxidases containing a Cys redox center; 1CysGPx; a glutathione peroxidase containing the CP only; 2CysGPxs; glutathione peroxidases containing both the CP and the CR; CP; peroxidatic Cys; CR; resolving Cys; GPx7; gluta

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Increased carbonylation of the lipid phosphatase PTEN contributes to Akt2 activation in a murine model of early alcohol-induced steatosis

Keywords: ALD; alcoholic liver disease; ALT; alanine aminotransferase; ChREBP; carbohydrate response element-binding protein; 4-HNE; 4-hydroxy-2-nonenal; NASH; nonalcoholic steatohepatitis; PI3K; phosphatidylinositol 3-kinase; PtdIns(3,4,5)P3; phosphatidylinositol

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Trypanothione: A unique bis-glutathionyl derivative in trypanosomatids

Keywords: 1-C-Grx; monothiol glutaredoxin; 2-C-Grx; dithiol glutaredoxin; CBS; cystathionine-β-synthase; CGL; cystathionine-γ-lyase; CHAP; cysteine histidine-dependent amidohydrolases/peptidases (protein domain); CS; cysteine synthase; DMPO; 5,5′-dimethyl-l-pyr

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2013 سفارش ترجمه

Functional proteomics approaches for the identification of transnitrosylase and denitrosylase targets

Keywords: 2DE; Two-dimensional gel electrophoresis; ACN; Acetonitrile; BB; Binding buffer; BCA; Bicinchoninic acid; Biotin-HPDP; N-[6-(Biotinamido)hexyl]-3′-(2′-pyridyldithio)-propionamide; BST; Biotin-switch technique; CID; Collision-induced dissociation; DDA;

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2013 سفارش ترجمه

Crystallographic and spectroscopic characterizations of Sulfolobus solfataricus TrxA1 provide insights into the determinants of thioredoxin fold stability

Keywords: RMSD; root mean square deviation; PDB; Protein Data Bank; Trx; thioredoxin; TrxR; thioredoxin reductase; SsTrxA2; Sulfolobus solfataricus Trx A2; SsTrxA1; Sulfolobus solfataricus Trx A1; EcTrx; Escherichia coli Trx; TtTrx; Thermus thermophilus Trx; SpTrx;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Research reportNeuroprotection of co-activation of GABA receptors by preventing caspase-3 denitrosylation in KA-induced seizures

Keywords: KA; kainic acid; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazole propionate; GABA; γ-Aminobutyric acid; FasL; Fas-ligand; FADD; Fas-associated death domain; DISC; death-inducing signaling complex; Trx; thioredoxin; TrxR; Trx reductase; SNO; S-nitrosothiol;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Entamoeba histolytica thioredoxin reductase: Molecular and functional characterization of its atypical properties

Keywords: TRXR; thioredoxin reductase; TRX; thioredoxin; GSNO; S‐nitrosoglutathione; CySNO; S-nitrosocysteine; MBQ; 2-methyl-benzoquinone; DTBBQ; 2-5-ditert-buthyl-benzoquinone; DTNB; 5-5´-dithio-nitrobenzoic acid; MB; methylene blue; MV; methyl viologen; CDNB;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

The selenoproteins GPx2, TrxR2 and TrxR3 are regulated by Wnt signalling in the intestinal epithelium

Keywords: GPx; glutathione peroxidase; TrxR; thioredoxin reductase; Gsk3β; glycogen synthase kinase 3β; APC; adenomatous polyposis coli; Dvl; dishevelled; Lgr5; leucine-rich repeat containing G protein-coupled receptor 5; Lrp; low density lipoprotein receptor-rel

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

The HDAC inhibitor depsipeptide transactivates the p53/p21 pathway by inducing DNA damage

Keywords: Ara-C; cytarabine; ATM; ataxiatelangiectasia-mutated; ATR; ATM- and Rad3-related; CAT; catalase; CHK2; the checkpoint kinase 2; CK1; casein kinase 1; DHE; dihydroethidium; DNA-PK; DNA-dependent serine/threonine protein kinase; Grx; glutaredoxin; HAT; hist

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Inhibition of thioredoxin reductase by a novel series of bis-1,2-benzisoselenazol-3(2H)-ones: Organoselenium compounds for cancer therapy

Keywords: TrxR; thioredoxin reductase; Trx; thioredoxin; GR; glutathione reductase; SAR; structure-activity relationship; DTNB; 5,5′-dithiol-bis-2-nitrobenzoic acid; Log Pcal; calculated Log P; BIAM; biotin-conjugated iodoacetamide; Organoselenium compound; T

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Redox-regulating role of insulin: The essence of insulin effect

Keywords: 4-HNE; 4-hydroxynonenal; 8-OHdG; 8-hydroxydeoxyguanosine; 8-OHG; 8-hydroxyguanine; 8-iso-PGF2α; 8-iso-prostaglandin F2α; AD; Alzheimer's disease; AIDS; acquired immunodeficiency syndrome; Akt; protein kinase B; AMI; acute myocardial infarction; APS; a

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2012 سفارش ترجمه

Induction of ROS, p53, p21 in DEHP- and MEHP-exposed LNCaP cells-protection by selenium compounds

Keywords: CM-H2DCFA; 5-(and 6-) chloromethyl-2′,7′-dichlorodihydrofluorescein diacetate; DAB; 3,3′-diaminobenzidine; DCF; 2′,7′-dichlorofluorescein; DEHP; di(2-ethylhexyl)phthalate; DR5; death receptor 5; FBS; fetal bovine serum; FCS; fetal calf serum; GP

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Inhibition of thioredoxin reductase 1 by porphyrins and other small molecules identified by a high-throughput screening assay

Keywords: TrxR; thioredoxin reductase; PpIX; protoporphyrin IX; NMPP; N-methylprotoporphyrin; qHTS; quantitative high-throughput screening; DMSO; dimethyl sulfoxide; Screening assay; Thioredoxin reductase; Inhibitor; Substrate; Protoporphyrin IX; Rottlerin; Cancer;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Thioredoxin glutathione reductase: Its role in redox biology and potential as a target for drugs against neglected diseases

Keywords: FAD; flavin adenine dinucleotide; Grx; glutaredoxin; GSH; glutathione; GSSG; glutathione disulfide; GR; glutathione disulfide reductase; PZQ; praziquantel; Sec; selenocysteine; SECIS; Sec insertion sequence; Trx; thioredoxin; TrxR; thioredoxin reductase;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Protective effect of tetraethyl pyrazine against focal cerebral ischemia/reperfusion injury in rats: Therapeutic time window and its mechanism

Keywords: FCIR; Focal Cerebral Ischemia Reperfusion; TMP; Tetramethyl Pyrazine; MCAO; Middle Cerebral Artery Occlusion; NDS; Neurologic Deficit Scores; Trx; Thioredoxin; TrxR; Thioredoxin Reductase; RT-PCR; Reverse Transcription-Polymerase Chain Reaction; TTC; Trip

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2009 سفارش ترجمه

Impact of oxidative stress on the health and immune function of dairy cattle

Keywords: GSH; glutathione; GSSG; oxidized glutathione; GR; glutathione reductase; GPX; glutathione peroxidase; LHP; lipid hydroperoxide; ROS; reactive oxygen species; Se; selenium; SOD; superoxide dismutase; Trx; thioredoxin; TrxR; thioredoxin reductase; Oxidative

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Exposure to monomethylarsonous acid (MMAIII) leads to altered selenoprotein synthesis in a primary human lung cell model

Keywords: MMAIII; Monomethylarsonous acid; TrxR; thioredoxin reductase; TrxR1; cytosolic thioredoxin reductase; QR; quinone reductase; ARE; antioxidant response element; cGpx; cytosolic glutathione peroxidase; PHGpx; phosphohydrolipid glutathione peroxidase; Monome

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Differential genomic and proteomic profiling of glioblastoma cells exposed to terpyridineplatinum(II) complexes

Keywords: Trx; thioredoxin; TrxR; thioredoxin reductase; TPCs; terpyridineplatinum(II) complexes; I232N; 4-mercaptopyridine (4′-chloro-2,2′:6′,2″-terpyridine)platinum(II) nitrate; I252N; 2-mercaptopyridine (2′-chloro-2,2′:6′,2″-terpyridine)platinum(

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2009 سفارش ترجمه

The inhibitory effect of diphenyltin on gap junctional intercellular communication in HEK-293 cells is reduced by thioredoxin reductase 1

Keywords: DiI; 1,1′-dioctadecyl-3,3,3′,3′-tetramethylindocarbocyanine perchlorate; DMEM; Dulbecco's modified Eagle's medium; DPhT; diphenyltin; GJIC; gap junctional intercellular communication; HEK-293 cells; human embryonic kidney cells; PKC; protein kin

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

PrxQ-A, a member of the peroxiredoxin Q family, plays a major role in defense against oxidative stress in the cyanobacterium Anabaena sp. strain PCC7120

Keywords: AMS; 4-acetamido-4′-maleimidyl-stilbene-2,2′-disulfonate; 2-Cys Prx-s; 2-cysteine Prx-s; DTT; dithiothreitol; MCO; metal-catalyzed oxidation; MV; methyl viologen; ORFs; open-reading frames; Prx-s; peroxiredoxins; ROS; reactive oxygen species; RT-PCR;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

A gold(I) phosphine complex selectively induces apoptosis in breast cancer cells: Implications for anticancer therapeutics targeted to mitochondria

Keywords: Δψm; mitochondrial membrane potential; DLC; delocalized lipophilic cation; MPT; membrane permeability transition; Auranofin; 2,3,4,6-tetra-O-acetyl-l-thio-β-d-glucopyranosato-S-triethylphosphine gold(I); TrxR; thioredoxin reductase; Trx; thioredoxin; [

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2007 سفارش ترجمه

An evolutionarily conserved 16-kDa thioredoxin-related protein is an antioxidant which regulates the NF-κB signaling pathway

Keywords: Cr-TRP16; C. rotundicauda thioredoxin-related protein; DTT; dithiothreitol; EMSA; electrophoretic gel mobility shift assay; GNB; gram-negative bacteria; IAM; iodoacetamide; iNOS; inducible nitric oxide synthase; MFO; mixed-function oxidase; PCR; polymeras

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2007 سفارش ترجمه

Inhibition of thioredoxin reductase but not of glutathione reductase by the major classes of alkylating and platinum-containing anticancer compounds

Keywords: TrxR; thioredoxin reductase; GR; glutathione reductase; BCNU; 1,3-bis(2-chloroethyl)-1-nitrosourea (carmustine); DTNB; 5,5′-dithiobis(2-nitrobenzoic acid); BSA; bovine serum albumin; PE; potassium phosphate-EDTA; TE; tris(hydroxymethyl)methylamine-EDTA;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2005 سفارش ترجمه