The ING tumor suppressor genes: Status in human tumors
Keywords: ژن سرکوب کننده تومور; ING1; ING4; Tumor suppressor gene; p53; MicroRNA;
مقالات ISI ژن سرکوب کننده تومور (ترجمه نشده)
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Epigallocatechin-3-gallate up-regulates tumor suppressor gene expression via a reactive oxygen species-dependent down-regulation of UHRF1
Keywords: ژن سرکوب کننده تومور; DNMT1; DNA methyltransferase1; EGCG; epigallocatechin-3-gallate; ROS; reactive oxygen species; UHRF1; Ubiquitin-like PHD, Ring finger 1; DNA methyltransferase 1; Epigallocatechin-3-gallate; P16INK4A; Tumor suppressor gene; Ubiquitin-like containing PHD an
A renal metanephric adenoma showing both a 2p16-24 deletion and BRAF V600E mutation: a synergistic role for a tumor suppressor gene on chromosome 2p and BRAF activation?
Keywords: ژن سرکوب کننده تومور; Metanephric adenoma; BRAF V600E mutation; chromosomal imbalance; tumor suppressor gene; short arm of chromosome 2;
p53-based therapeutics for head and neck squamous cell carcinoma
Keywords: ژن سرکوب کننده تومور; Tumor suppressor gene; p53; Anti-cancer therapeutics; Head and neck cancer; Oral cancer; Gene therapy; Human papillomavirus
Oxidative stress causes epigenetic alteration of CDX1 expression in colorectal cancer cells
Keywords: ژن سرکوب کننده تومور; CDX1, caudal type homeobox-1; ROS, reactive oxygen species; 5-Aza-dC, 5-aza-2-deoxycytidine; DNMT, DNA methyltransferase; HDAC, histone deacetylase; MS-PCR, methylation-specific-polymerase chain reactionCaudal type homeobox-1; Tumor suppressor gene; Color
Epithelial membrane protein 3 is frequently shown as promoter methylation and functions as a tumor suppressor gene in non-small cell lung cancer
Keywords: ژن سرکوب کننده تومور; Lung cancer; EMP3; Tumor suppressor gene; Prognosis
Analysis of the NCI-60 dataset for cancer-related microRNA and mRNA using expression profiles
Keywords: ژن سرکوب کننده تومور; MicroRNA; Expression profile; Oncogene; Tumor suppressor gene; Pearson correlation; Spearman rank correlation; CpG island; MicroRNA cluster; Fragile sites
Frameshift mutations of tumor suppressor gene EP300 in gastric and colorectal cancers with high microsatellite instability
Keywords: ژن سرکوب کننده تومور; Cancer; EP300; Microsatellite instability; Mutation; Tumor suppressor gene
Potentialities of aberrantly methylated circulating DNA for diagnostics and post-treatment follow-up of lung cancer patients
Keywords: ژن سرکوب کننده تومور; Lung cancer; Diagnostics; Prognosis; Monitoring; Circulating DNA; Methylation; Tumor suppressor gene
Studies on the interaction mechanism of aminopyrene derivatives with human tumor-related DNA
Keywords: ژن سرکوب کننده تومور; Polycyclic aromatic hydrocarbons derivatives; Oncogene; Tumor suppressor gene; DNA interaction; PAGE
Genotoxicity and carcinogenicity risk of carbon nanotubes
Keywords: ژن سرکوب کننده تومور; CNT, carbon nanotube; MWCNT, multiwalled carbon nanotube; SWCNT, single-walled carbon nanotubeAsbestos; CDKN2A/2B; Homozygous deletion; Mesothelial cell; Mesothelioma; Mutation; Tumor suppressor gene
VGLL3 expression is associated with a tumor suppressor phenotype in epithelial ovarian cancer
Keywords: ژن سرکوب کننده تومور; High-grade ovarian serous carcinomas; Microcell-mediated chromosome transfer; VGLL3; Tumor suppressor gene; Chromosome 3; 3p12; Gene transfection; Gene expressionHGSC, high-grade serous carcinomas; MMCT, microcell-mediated chromosome transfer; MVB, multiv
Hypermethylation of E-cadherin, p16, p14, and RASSF1A genes in pathologically normal urothelium predict bladder recurrence of bladder cancer after transurethral resection
Keywords: ژن سرکوب کننده تومور; Gene methylation; Tumor suppressor gene; Bladder cancer; Tumor recurrence
The role of zinc transporter ZIP4 in prostate carcinoma
Keywords: ژن سرکوب کننده تومور; ZIP4; Zinc transporter; Prostate; Carcinoma; Proliferation; Invasion; Tumor suppressor gene
Tumor suppressor cell adhesion molecule 1 (CADM1) is cleaved by a disintegrin and metalloprotease 10 (ADAM10) and subsequently cleaved by γ-secretase complex
Keywords: ژن سرکوب کننده تومور; CADM1; ADAM10; γ-Secretase; Shedding; RIP; Tumor suppressor gene
The p53 inhibitor, pifithrin-α, suppresses self-renewal of embryonic stem cells
Keywords: ژن سرکوب کننده تومور; ES cells; Tumor suppressor gene; Nanog; Cyclin D1; Proliferation
The regulatory roles of miRNA and methylation on oncogene and tumor suppressor gene expression in pancreatic cancer cells
Keywords: ژن سرکوب کننده تومور; MicroRNA; Dicer 1; Tumor suppressor gene; Oncogene; Methylation; Pancreatic cancer
LRRC3B gene is frequently epigenetically inactivated in several epithelial malignancies and inhibits cell growth and replication
Keywords: ژن سرکوب کننده تومور; Cancer; Tumor suppressor gene; NotI microarrays; Methylation; RT-qPCR
Deciphering the molecular genetic basis of NPC through molecular, cytogenetic, and epigenetic approaches
Keywords: ژن سرکوب کننده تومور; Nasopharyngeal Carcinoma; Epstein–Barr Virus; Tumorigenesis; Tumor suppressor gene; Oncogene; DNA methylation
Deciphering the molecular genetic basis of NPC through functional approaches
Keywords: ژن سرکوب کننده تومور; TSG; tumor suppressor gene; NPC; nasopharyngeal carcinoma; MCH; microcell hybrid; MMCT; microcell-mediated chromosome transfer; YAC; yeast artificial chromosome; P1; bacteriophage P1 cloning system; PAC; P1-derived artificial chromosome; BAC; bacterial ar
The p53-p21WAF1 checkpoint pathway plays a protective role in preventing DNA rereplication induced by abrogation of FOXF1 function
Keywords: ژن سرکوب کننده تومور; FOXF1; Tumor suppressor gene; DNA rereplication; p53; p21WAF1;
Survival signaling in the preimplantation embryo
Keywords: ژن سرکوب کننده تومور; Tumor suppressor gene; phosphatidylinositol-3-kinase; Paf; CREB; transcription; AKT
Genetically engineered mouse models shed new light on the pathogenesis of neurofibromatosis type I-related neoplasms of the peripheral nervous system
Keywords: ژن سرکوب کننده تومور; Neurofibromatosis; Schwann cell; Tumor suppressor gene; Tumor microenvironment; Aberrant growth factor signaling
Chromatin-modifying agents in anti-cancer therapy
Keywords: ژن سرکوب کننده تومور; Epigenetic inhibitors; HDAC; DNMT; Anti-cancer therapy; Clinical trials; Combinatory treatments; AML; acute myeloid leukemia; AZA; 5-azacytidine; CMA; chromatin-modifying agent; CML; chronic myeloid leukemia; CMML; chronic myelomonocytic leukemia; CTCL; c
Molecular insights into the proliferation and progression mechanisms of the oral cancer: Strategies for the effective and personalized therapy
Keywords: ژن سرکوب کننده تومور; Oral cancer; Tumor suppressor gene; Apoptosis; Cytokine; Transcriptional factor; Ant-cancer drug
Integrative Genomic Identification of Genes on 8p Associated With Hepatocellular Carcinoma Progression and Patient Survival
Keywords: ژن سرکوب کننده تومور; Liver Cancer; Tumor Profiling; Cancer Driver Genes; arrayCGH; array-based comparative genomic hybridization; HBV; hepatitis B virus; HCC; hepatocellular carcinoma; LCI; Liver Cancer Institute; LEC; Laboratory of Experimental Carcinogenesis; mRNA; messenge
Aberrant expression of CKLF-like MARVEL transmembrane member 5 (CMTM5) by promoter methylation in myeloid leukemia
Keywords: ژن سرکوب کننده تومور; Acute myeloid leukemia; Chronic myeloid leukemia; CMTM5; Methylation; Tumor suppressor gene;
Aberrant methylation of the RIZ1 gene in myelodysplastic syndrome and acute myeloid leukemia
Keywords: ژن سرکوب کننده تومور; Myelodysplastic syndrome; Acute myeloid leukemia; Methylation; RIZ1; Tumor suppressor gene; Epigenetics
Quantitative analysis of multiple methylated genes in plasma for the diagnosis and prognosis of hepatocellular carcinoma
Keywords: ژن سرکوب کننده تومور; HCC; hepatocellular carcinoma; MSRE; methylation-sensitive restriction enzymes; qPCR; quantitative polymerase chain reaction; AFP; α-fetoprotein; TSG; tumor suppressor gene; ROC; receiver operator characteristic curve; AUC; area under the curve; MP; meth
p16 Expression: A marker of differentiation between childhood malignant melanomas and Spitz nevi
Keywords: ژن سرکوب کننده تومور; benign melanocytic nevus; childhood; nodular melanoma; p16; Spitz nevus; Spitzoid malignant melanoma; tumor suppressor gene
Loss of heterozygosity in oral cancer
Keywords: ژن سرکوب کننده تومور; Oral squamous cell carcinoma; Loss of heterozygosity; Tumor suppressor gene
Regulation of tumor suppressor gene FUS1 expression by the untranslated regions of mRNA in human lung cancer cells
Keywords: ژن سرکوب کننده تومور; FUS1/TUSC2; Tumor suppressor gene; Lung cancer; Untranslated region (UTR); Upstream open reading frame (uORF); Protein expression regulation;
Identification of the bleomycin hydrolase gene as a methylated tumor suppressor gene in hepatocellular carcinoma using a novel triple-combination array method
Keywords: ژن سرکوب کننده تومور; Hepatocellular carcinoma; Bleomycin hydrolase; Tumor suppressor gene; Expression array; Single nucleotide polymorphism array; Methylation array
Deletion of the inhibitor of growth 4 (ING4) tumor suppressor gene is prevalent in human epidermal growth factor 2 (HER2)-positive breast cancer
Keywords: ژن سرکوب کننده تومور; ING4; Tumor suppressor gene; Breast cancer; FISH; HER2/neu
C/EBP ζ targets to neutrophil gelatinase-associated lipocalin (NGAL) as a repressor for metastasis of MDA-MB-231 cells
Keywords: ژن سرکوب کننده تومور; NGAL; neutrophil gelatinase-associated lipocalin; EMT; epithelial to mesenchymal transition; ER; estrogen receptors; TSG; tumor suppressor gene; DDIT3; DNA damage-inducible transcript 3; ESCC; oesophageal squamous cell carcinoma; CM; conditioned medium; N
Viral hit and run-oncogenesis: Genetic and epigenetic scenarios
Keywords: ژن سرکوب کننده تومور; Epstein-Barr virus; Tumor virus; Recombination; Chromatin; DNA-methylation; Transformation; Tumor suppressor gene;
DNA methylation detection using MS-qFRET, a quantum dot-based nanoassay
Keywords: ژن سرکوب کننده تومور; DNA methylation; Nanotechnology; Promoter hypermethylation; QD-FRET; Quantum dots; AML; acute myeloid leukemia; FRET; fluorescence resonance energy transfer; IVD; in vitro methylated DNA; MDS; myelodysplastic syndrome; MSP; methylation specific PCR; MS-qF
FOXO1 is a direct target of EWS-Fli1 oncogenic fusion protein in Ewing’s sarcoma cells
Keywords: ژن سرکوب کننده تومور; Ewing’s sarcoma; EWS-Fli1; Oncogenic fusion protein; FOXO1; RNA interference; Inducible siRNA; Tumor suppressor gene
Frequent promoter hypermethylation of TGFBI in epithelial ovarian cancer
Keywords: ژن سرکوب کننده تومور; DNA hypermethylation; Epigenetics; Ovarian cancer; TGFBI; Tumor suppressor gene; Biomarker; Diagnosis; Microarray
Research ArticleEpigenetic inactivation of the tumor suppressor gene RIZ1 in hepatocellular carcinoma involves both DNA methylation and histone modifications
Keywords: ژن سرکوب کننده تومور; HCC; hepatocellular carcinoma; LOH; loss of heterozygosity; TSG; tumor suppressor gene; RIZ1; retinoblastoma-interacting zinc finger; ChIP; chromatin immunoprecipitation; 5-Aza-dC; 5-aza-2-deoxycitidine; TSA; Trichostatin A; DNMT; DNA methyltransferase; H
Prédispositions génétiques aux cancers : actualités et perspectives en 2010
Keywords: ژن سرکوب کننده تومور; Gène de prédisposition aux cancers; Gène de susceptibilité aux cancers; Oncogène; Gène suppresseur de tumeur; INCaHereditary cancer gene; Cancer susceptibility gene; Oncogene; Tumor suppressor gene; French National Cancer Institute
The tumor suppressor Rb and its related Rbl2 genes are regulated by Utx histone demethylase
Keywords: ژن سرکوب کننده تومور; Tumor suppressor gene; Histone demethylase; JmjC domain; Transcription; Rb;
Leukemia inhibitory factor receptor (LIFR) is detected as a novel suppressor gene of hepatocellular carcinoma using double-combination array
Keywords: ژن سرکوب کننده تومور; Hepatocellular carcinoma; Leukemia inhibitory factor receptor; Tumor suppressor gene; Expression array; Single nucleotide polymorphism array
RBM5/H37 tumor suppressor, located at the lung cancer hot spot 3p21.3, alters expression of genes involved in metastasis
Keywords: ژن سرکوب کننده تومور; RBM5/H37; 3p21.3; Tumor suppressor gene; Lung cancer; Microarray; Metastasis; Extracellular matrix; Gene knockdown
Silencing of Cited2 and Akap12 genes in radiation-induced rat osteosarcomas
Keywords: ژن سرکوب کننده تومور; Tumor suppressor gene; Osteosarcoma; Ionizing radiationOS, osteosarcoma; OB, osteoblast; CGH, comparative genomic hybridization, RT-PCR, reverse transcription-polymerase chain reaction
ZIC1 is downregulated through promoter hypermethylation in gastric cancer
Keywords: ژن سرکوب کننده تومور; ZIC1; Methylation; Tumor suppressor gene; Gastric cancer
Methyl-CpG targeted recruitment of p300 reactivates tumor suppressor genes in human cancer cells
Keywords: ژن سرکوب کننده تومور; MeTA; MBD; CpG island; Transcriptional repression; Tumor suppressor gene; Histone modification; p300; NFκB; Transcriptional activation domain
Relationships between replication timing and GC content of cancer-related genes on human chromosomes 11q and 21q
Keywords: ژن سرکوب کننده تومور; Mb, megabase; PCR, polymerase chain reaction; SNP, single nucleotide polymorphism; STS, sequence-tagged siteHuman genome; S phase; Isochore border; Genomic instability; Oncogene; Tumor suppressor gene
The role of KLF6 and its splice variants in cancer therapy
Keywords: ژن سرکوب کننده تومور; Apoptosis; Alternative mRNA splicing; Tumor suppressor gene; siRNA targeting
Epigenetic dysregulation of the host cell genome in Epstein–Barr virus-associated neoplasia
Keywords: ژن سرکوب کننده تومور; Epstein–Barr virus; Latency; Epigenetic regulation; Tumor suppressor gene; Nasopharyngeal carcinoma; Gastric carcinoma