Keywords: Prostate epithelial cells; Neoplastic conversion; Tumorigenicity; Cancer stem cell;
مقالات ISI (ترجمه نشده)
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Keywords: Pluripotent stem cells; Tumorigenicity; Regenerative medicine; Glycan; Lectin;
Keywords: Regenerative medicine; Cellular therapy; Tumorigenicity; Bone marrow-derived mesenchymal stem cell; Adipose-derived stem cell; Quality assessment; hCTP; human cell-processed therapeutic product; BMSC; bone marrow-derived mesenchymal stem cell; ADSC; adipo
Keywords: BAK; BCL-2 antagonist killer; BAX; BCL-2 associated X protein; CDK1; cyclin dependent kinase 1; CLDN-6; claudin-6; CM; cardiomyocyte; CPE; Clostridium perfringens endotoxin; GPX2; glutathione peroxidase-2; GSH; glutathione; GSR; glutathione reductase; GSS
Keywords: EphA3; Transformation; Mutation; Tumorigenicity; Colorectal epithelial cells;
Keywords: Umbilical cord-derived mesenchymal stem cells; Liver injury; Toxicity; Tumorigenicity; Biodistribution;
Keywords: Bone tissue engineering; Biocompatibility; Tumorigenicity; Microenvironment; Oral squamous cell carcinoma; BMP-2;
Keywords: magnetic resonance imaging; ultrasound imaging; serum biomarker; microRNA biomarker; pluripotent stem cells; tumorigenicity
Keywords: Oral cancer; Cancer stem cells; Therapy resistance; Tumorigenicity;
Keywords: Regenerative medicine; Cellular therapy; Tumorigenicity; Mesenchymal stem cell; Quality; Safety;
Keywords: Cancer stem cell; Hypothesis; Intratumor heterogeneity; Xenografts; PDX; Tumorigenicity;
Keywords: Cancer stem cells; Immortal Strand Hypothesis; Tumorigenicity; Asymmetric cell division; Symmetric cell division; Cancer;
Keywords: Polycyclic aromatic hydrocarbons; TEF; Tumorigenicity;
Keywords: OX40Lexo, extracellular domain of the OX40 ligand, 50–198 aa; OX40Lfull, the complete OX40 ligandSoluble OX40L; CT26 colon carcinoma; Tumorigenicity; Antitumor immune response; Immunological memory
Combined seven miRNAs for early hepatocellular carcinoma detection with chronic low-dose exposure to microcystin-LR in mice
Keywords: Environmental toxicants; miRNAs; Tumorigenicity; Microcystin-LR;
A novel lncRNA, Lnc-OC1, promotes ovarian cancer cell proliferation and migration by sponging miR-34a and miR-34c
Keywords: Ovarian cancer; Lnc-OC1; miR-34a; miR-34c; Tumorigenicity; ceRNA; competing endogenous RNAs; EMT; epithelial-mesenchymal transition; GEO; Gene Expression Omnibus; LncRNAs; long non-coding RNAs; miRNA; microRNA; OC; ovarian cancer; RNA-FISH; RNA-fluorescen
The influence of peroxisome proliferator-activated receptor γ (PPARγ) ligands on cancer cell tumorigenicity
Keywords: Cancer cells; PPARγ agonist; PPARγ antagonist; Therapeutic agents; Tumorigenicity; ACC; Acetyl-CoA carboxylase; AKR1B10; Alde-keto reductase 1B10; Alpha-ESA; Alpha-eleostreac acid; ACLY; ATP citrate lyase; BADGE; Bisphenol-A-diglycidyl-etter; CSCs; Canc
In vitro and in vivo characterization of stem-like cells from canine osteosarcoma and assessment of drug sensitivity
Keywords: OSA; osteosarcoma; CSCs; cancer stem cells; CXCR4; C-X-C motif chemokine receptor 4; CXCL12; C-X-C motif chemokine ligand 12; CD117; KIT proto-oncogene receptor tyrosine kinase; STAT3; signal transducer and activator of transcription 3; Oct4; POU class 5
Low dose assessment of the carcinogenicity of furan in male F344/N Nctr rats in a 2-year gavage study
Keywords: Furan; Tumorigenicity; Cholangiocarcinoma; Cholangiofibrosis; Rats; Bioassay; BMD; benchmark dose; BMDL; lower limit of benchmark dose; BW; body weight; FDA; Food and Drug Administration; GLP; Good Laboratory Practice; MOE; margin of exposure; NCTR; Natio
Crosstalk of the Wnt/β-catenin pathway with other pathways in cancer cells
Keywords: β-catenin; Cell signaling; Glioma stem cell; Tumorigenicity; Wnt
SOX9-mediated upregulation of LGR5 is important for glioblastoma tumorigenicity
Keywords: Glioblastoma; Leucine-rich repeat-containing G protein-coupled receptor 5 (LGR5); Sry-related high-mobility group (HMG) box 9 (SOX9); Tumorigenicity;
MicroRNA-373 functions as an oncogene and targets YOD1 gene in cervical cancer
Keywords: miR-373; Human cervical cancer; Tumorigenicity; YOD1;
Heterogeneous nuclear ribonucleoprotein K upregulates the kinetochore complex component NUF2 and promotes the tumorigenicity of colon cancer cells
Keywords: Heterogeneous nuclear ribonucleoprotein K (hnRNP K); NDC80 kinetochore complex component NUF2; Colorectal cancer; Tumorigenicity; hnRNP K; heterogeneous nuclear ribonucleoprotein K; qRT-PCR; quantitative real-time PCR; CIN; chromosome instability;
Highly sensitive droplet digital PCR method for detection of residual undifferentiated cells in cardiomyocytes derived from human pluripotent stem cells
Keywords: HiPSCs; HiPSC-derived cell therapy products; Quality control; Tumorigenicity; ddPCR; LIN28
Carcinogenicity of glycidamide in B6C3F1 mice and F344/N rats from a two-year drinking water exposure
Keywords: Acrylamide; Glycidamide; Tumorigenicity; Mice; Rats; Bioassay; ANOVA; analysis of variance; BMD; benchmark dose; BMDL; lower limit of benchmark dose; N3-GA-Ade; N3-(2-carbamoyl-2-hydroxyethyl)adenine; N7-GA-Gua; N7-(2-carbamoyl-2-hydroxyethyl)guanine; NCT
FBI1/Akirin2 promotes tumorigenicity and metastasis of Lewis lung carcinoma cells
Keywords: LLC; Lewis lung carcinoma; MKP; MAPK phosphatase; ECM; extracellular matrix; 14-3-3β; 14-3-3 beta interactant 1/Akirin2; Anchorage-independent growth; Tumorigenicity; Metastasis;
Establishment and characterization of a rare atypical chronic myeloid leukemia cell line NT-1
Keywords: Atypical chronic myeloid leukemia; Cell line; Translocation; Tumorigenicity;
PCDH10 is required for the tumorigenicity of glioblastoma cells
Keywords: Protocadherin PCDH10; OL-protocadherin; Glioblastoma; Tumorigenicity; Proliferation
MicroRNAs as potential biomarkers for VERO cell tumorigenicity
Keywords: African green monkey kidney (VERO) cells; Neoplastic development; Transformation; Tumorigenicity; miRNA; Biomarkers;
PTEN inhibits the invasion and metastasis of gastric cancer via downregulation of FAK expression
Keywords: PTEN; phosphatase and tensin homolog; FAK; focal adhesion kinase; AKT; protein kinase B; NF-κB; nuclear factor B or NF-kappaB; ChIP; chromatin immunoprecipitation; EMSA; electrophoretic mobility shift assay; DAPI; 4â²,6-diamidino-2-phenylindole; Focal a
Carcinogenicity of acrylamide in B6C3F1 mice and F344/N rats from a 2-year drinking water exposure
Keywords: BMD; benchmark dose; BMDL; lower limit of benchmark dose; CNS; central nervous system; N3-GA-Ade; N3-(2-carbamoyl-2-hydroxyethyl)adenine; N7-GA-Gua; N7-(2-carbamoyl-2-hydroxyethyl)guanine; NCTR; National Center for Toxicological Research; NTP; National To
Advances in cellular reprogramming: Moving toward a reprieve from immunogenicity
Keywords: Immunogenicity; iPSC; Reprogramming; Lineage conversion; Tumorigenicity;
Clinical Therapy Using iPSCs: Hopes and Challenges
Keywords: iPSC; Regenerative medicine; Disease modeling; Immunogenicity; Tumorigenicity
Risk of tumorigenicity in mesenchymal stromal cell–based therapies—Bridging scientific observations and regulatory viewpoints
Keywords: cell; mesenchymal; stromal; tumorigenicity
Suppression of non-small cell lung cancer proliferation and tumorigenicity by DENND2D
Keywords: DENND2D; Gene expression; Non-small cell lung cancer; Proliferation; Tumorigenicity; Apoptosis
TrkB/BDNF signaling pathway is a potential therapeutic target for pulmonary large cell neuroendocrine carcinoma
Keywords: LCNEC; TrkB; BDNF; Invasion; Tumorigenicity; Lung cancer
Holy Basil leaf extract decreases tumorigenicity and metastasis of aggressive human pancreatic cancer cells in vitro and in vivo: Potential role in therapy
Keywords: Basil; Pancreatic cancer; Therapy; Apoptosis; Tumorigenicity
The zinc finger transcription factor ZKSCAN3 promotes prostate cancer cell migration
Keywords: ZKSCAN3; Prostate cancer; Cell metastasis; Cell migration; Tumorigenicity;
Alterations in microRNA expression linked to microcystin-LR-induced tumorigenicity in human WRL-68 Cells
Keywords: Microcystin-LR; miRNA; Tumorigenicity; Environmental inspection
Mammosphere cells from high-passage MCF7 cell line show variable loss of tumorigenicity and radioresistance
Keywords: SLCs, stem-like cancer cells; BSLCs, breast stem-like cancer cells; MSs, mammosphere cells; ROS, reactive oxygen species; ATM, ataxia telangiectasia mutatedStem-like cancer cells; Mammosphere cells; Tumorigenicity; Radiation sensitivity
Nonclinical safety strategies for stem cell therapies
Keywords: Stem cells; Biodistribution; Immunogenicity; Tumorigenicity; Toxicology; Safety studies
An RNA-seq-based Gene Expression Profiling of Radiation-induced Tumorigenic Mammary Epithelial Cells
Keywords: NGS; RNA-seq; Tumorigenicity; Immortality; Radiation; Breast cancer
Knockdown of stromal interaction molecule 1 (STIM1) suppresses store-operated calcium entry, cell proliferation and tumorigenicity in human epidermoid carcinoma A431 cells
Keywords: Stromal interaction molecule 1 (STIM1); Store-operated calcium entry; Proliferation; Tumorigenicity; RNA interference; Human epidermoid carcinoma A431 cells;
Evaluation of tumorigenic potential of high yielding cloned MDCK cells for live-attenuated influenza vaccine using in vitro growth characteristics, metastatic gene expression and in vivo nude mice model
Keywords: Influenza virus; MDCK cells; Vaccine safety; Tumorigenicity; In vitro assays;
Inhibitory effect of siRNA targeting IGF-1R on endometrial carcinoma
Keywords: RNA interference; Tumorigenicity; The type-1 insulin-like growth factor receptor; Endometrial carcinoma;
Establishment and characterization of a rabbit oral squamous cell carcinoma cell line as a model for in vivo studies
Keywords: Oral cancer; Tongue squamous cell carcinoma; Rabbit; Cell line; Tumorigenicity
Characterization of Agrobacterium vitis isolates obtained from galled grapevine plants in Egypt
Keywords: Agrobacterium vitis; Vitis vinifera; Tumorigenicity; Grape necrosis; Multiplex PCR
Nanog-induced dedifferentiation of p53-deficient mouse astrocytes into brain cancer stem-like cells
Keywords: Nanog; Brain cancer stem cell-like cells; p53−/− Astrocytes; Dedifferentiation; Tumorigenicity
Suppression of tumorigenicity of rhabdoid tumor derived G401 cells by the multivalent HB-19 pseudopeptide that targets surface nucleolin
Keywords: Surface nucleolin; Antagonist peptide; G401 cells; Tumorigenicity; Contact inhibition; HB-19; the surface nucleolin antagonist-pseudopeptide that presents pentavalently the tripeptide KÏ(CH2N)PR; WT1; Wilms' tumor 1; WT1-R; WT1 related; MK; Midkine; CD
Unrestricted somatic stem cells: interaction with CD34+ cells in vitro and in vivo, expression of homing genes and exclusion of tumorigenic potential
Keywords: CD34; co-transplantation; engraftment; tumorigenicity; unrestricted somatic stem cells