دانلود مقالات ISI درباره سیستم Ubiquitin-proteasome + ترجمه فارسی

تجزیه و تحلیل توده اسپکترومتری از اتاکسین-3 گسترش یافته به سلول های نرمال و پلیگلوتامین نشان می دهد که همکاران جدید درگیر در عملکرد میتوکندری

Mass spectrometry analyses of normal and polyglutamine expanded ataxin-3 reveal novel interaction partners involved in mitochondrial function

Keywords: سیستم Ubiquitin-proteasome; Spinocerebellar ataxia type 3; Ataxin-3; Mass spectrometry; Protein interaction; Mitochondria; Atx3; Ataxin-3; CHIP; C-terminus of 70 kDa heat shock protein; E3s; E3 ubiquitin-protein ligases; HD; Huntington's disease; polyQ; polyglutamine; UPS; ubiquiti

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2018 سفارش ترجمه

مهارکننده های ایمونو پروتئازوم-انتخابی و غیر انتخابی: یک رویکرد امیدوار کننده برای درمان بیماری های مختلف میلوما

Immunoproteasome-selective and non-selective inhibitors: A promising approach for the treatment of multiple myeloma

Keywords: سیستم Ubiquitin-proteasome; AE; Adverse event; BIPN; Bortezomib-induced peripheral neuropathy; C-L; Caspase-like; CFZ; Carfilzomib; ChT-L; Chymotrypsin-like action; IRd; Ixazomib, lenalidomide, and dexamethasone; LG; Leaving group; MM; Multiple myeloma; MTD; Maximum tolerated dose;

دانلود رایگان متن کامل مقاله ISI 77 صفحه سال انتشار : 2018 سفارش ترجمه

افزایش سوخت و ساز بدن در مغز به منظور افزایش میزان اتوفایگی متمرکز شده توسط کلر و چپرون برای کاهش سمیت پروتئین عصبی و پیری

Augmenting brain metabolism to increase macro- and chaperone-mediated autophagy for decreasing neuronal proteotoxicity and aging

Keywords: سیستم Ubiquitin-proteasome; AD; Alzheimer disease; ATP; adenosine triphosphate; AMP; adenosine monophosphate; AMPK; AMP-activated protein kinase; BDNF; brain derived neurotrophic factor; CMA; chaperone-mediated autophagy; CR; caloric restriction; Ex; exercise; GABA; gamma-aminobutyr

دانلود رایگان متن کامل مقاله ISI 63 صفحه سال انتشار : 2017 سفارش ترجمه

پیوند پراکسیداسیون لیپید و اختلالات روانپزشکی: تمرکز بر 4-هیدروکسی-2-غیر سلولی

Linking lipid peroxidation and neuropsychiatric disorders: focus on 4-hydroxy-2-nonenal

Keywords: سیستم Ubiquitin-proteasome; 6-OHDA; 6-hydroxydopamine; α-syn; α-synuclein; ACC; Anterior Cingulate Cortex; ADMA; asymmetric dimethylarginine; Alda-1; N-(1,3-Benzodioxol-5-ylmethyl)-2,6-dichlorobenzamide; Aldh1/Aldh2; aldehyde dehydrogenases 1/2; ALDH2; mitochondrial aldehyde dehyd

دانلود رایگان متن کامل مقاله ISI 67 صفحه سال انتشار : 2017 سفارش ترجمه

کنترل جریان شفاف در تشخیص عصبی: هدف گیری پیشرفت و دقیق-کجا ما ایستاده ایم؟

Autophagic flux control in neurodegeneration: Progress and precision targeting-Where do we stand?

Keywords: سیستم Ubiquitin-proteasome; Atg; autophagy related; AD; Alzheimer's disease; HD; Huntigton's disease; PD; Parkinson's disease; UPS; ubiquitin-proteasome system; CMA; chaperone-mediated autophagy; ER; endoplasmic reticulum; FD; fascia dentate; LC3; microtubule-associated light

دانلود رایگان متن کامل مقاله ISI 81 صفحه سال انتشار : 2017 سفارش ترجمه

هدف قرار دادن سیستم تخریب بتنی وعده غذایی برای درمان سرطان پستان را فراهم می آورد

Targeting Notch degradation system provides promise for breast cancer therapeutics

Keywords: سیستم Ubiquitin-proteasome; Notch; Ubiquitin-proteasome system; Degradation; Breast cancer; Therapy;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

از عدم فعالیت فیزیکی تا بی حرکت شدن: نقش استرس اکسیداتیو در مقاومت به انسولین عضلانی اسکلتی و آتروفی

From physical inactivity to immobilization: Dissecting the role of oxidative stress in skeletal muscle insulin resistance and atrophy

Keywords: سیستم Ubiquitin-proteasome; Insulin resistance; Autophagy; Ubiquitin-proteasome system; Apoptosis; H2O2; Hindlimb unloading; Xanthine oxidase; Exercise

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

استرس تناسلی اندوپلاسمی در چاقی و اختلالات مرتبط با چاقی: یک دیدگاه گسترده

Endoplasmic reticulum stress in obesity and obesity-related disorders: An expanded view

Keywords: سیستم Ubiquitin-proteasome; ATF4; activating transcription factor-4; ATF6α; activating transcription factor-6α; EB1; end binding protein-1; EDEM; ER degradation-enhancing α-like protein; ER; endoplasmic reticulum; ERAD; ER-associated degradation; GCN2; general control non-derepre

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2016 سفارش ترجمه

پیشرفت های اخیر در استراتژی های درمانی که بر تنظیم بیان کانال یون تمرکز می کنند

Recent advances in therapeutic strategies that focus on the regulation of ion channel expression

Keywords: سیستم Ubiquitin-proteasome; Ca2+ channel; K+ channel; Ca2+-activated Cl− channel; Transcription; Pre-mRNA splicing; Protein degradation; AD; Alzheimer's disease; ADPR; ADP ribose; AITC; allyl isothiocyanate; AKAP; A-kinase anchoring protein; AMPK; 5′ AMP-activated protein kinase

دانلود رایگان متن کامل مقاله ISI 171 صفحه سال انتشار : 2016 سفارش ترجمه

پروفیل بیان ژن، نقش جدید ایمونو پروتئازوم را در سمیت قلبی ناشی از دوکسوروبیسین مشخص می کند

Gene expression profiling identifies the novel role of immunoproteasome in doxorubicin-induced cardiotoxicity

Keywords: سیستم Ubiquitin-proteasome; DOX; doxorubicin; ROS; reactive oxygen species; UPS; ubiquitin-proteasome system; E1s; ubiquitin activating enzymes; E2s; ubiquitin conjugating enzymes; E3s; ubiquitin ligases; DUBs; deubiquitinases; Cardiotoxicity; Doxorubicin; Apoptosis; Ubiquitin-prote

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

دینامیک پروتئازوم

Proteasome dynamics

Keywords: سیستم Ubiquitin-proteasome; Ubiquitin-proteasome system; Nuclear transport; Nuclear protein degradation; Proteasome assembly; Quiescence; Proteasome storage granuli;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

پیوند فعالیت بورتزومیب در بیماری های مختلف میلوم و بیماری های خود ایمنی

Linking the activity of bortezomib in multiple myeloma and autoimmune diseases

Keywords: سیستم Ubiquitin-proteasome; Multiple myeloma; Bortezomib; Resistance; Ubiquitin-proteasome system; Autoimmune diseases; Proteostasis

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

نانوذرات سیلیکا باعث القای القایی آلفا synuclein و تجمع در سلول های PC12 می شود

Silica nanoparticles induce alpha-synuclein induction and aggregation in PC12-cells

Keywords: سیستم Ubiquitin-proteasome; Silica nanoparticles; Parkinson diseases; Alpha-synuclein; Ubiquitin-proteasome system; Autophagy

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Loss of NRF-2 and PGC-1α genes leads to retinal pigment epithelium damage resembling dry age-related macular degeneration

Keywords: سیستم Ubiquitin-proteasome; ER; endoplasmic reticulum; AMD; age-related macular degeneration; RPE; retinal pigment epithelium; PUFAs; polyunsaturated fatty acids; ROS; reactive oxygen species; NRF-2; nuclear factor-erythroid 2-related factor-2; ARE; antioxidant response element; Kea

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2019 سفارش ترجمه

Ethanol withdrawal limits fear memory reactivation-induced molecular events associated with destabilization phase: Influence of d-cycloserine

Keywords: سیستم Ubiquitin-proteasome; Ethanol withdrawal; Fear memory reconsolidation; NMDA receptor; Ubiquitin-proteasome system; Basolateral amygdala;

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2019 سفارش ترجمه

Ubiquitin-activating enzyme E1 inhibitor PYR-41 retards sperm enlargement after fusion to the egg

Keywords: سیستم Ubiquitin-proteasome; Ubiquitin-proteasome system; UBE1; PYR-41; Sperm enlargement; β-catenin;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2018 سفارش ترجمه

ZSCAN4 is negatively regulated by the ubiquitin-proteasome system and the E3 ubiquitin ligase RNF20

Keywords: سیستم Ubiquitin-proteasome; ZSCAN4; RNF20; Proteasome; Lysine-48 ubiquitination; Cancer; Stem cells; Telomeres; UPS; ubiquitin-proteasome system; ES cells; embryonic stem cells; iPS cells; induced pluripotent stem cells; Dox; doxycycline; CHX; cycloheximide; co-IP; co-immunoprecipit

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2018 سفارش ترجمه

Aim for the core: suitability of the ubiquitin-independent 20S proteasome as a drug target in neurodegeneration

Keywords: سیستم Ubiquitin-proteasome; 20S; core 20S proteasome; AD; Alzheimer's disease; ALS; amyotrophic lateral sclerosis; ATP; adenosine triphosphate; BBB; blood-brain barrier; DUB; deubiquitinating enzyme; HbYX; hydrophobic-tyrosine-unspecified residue 'X'; IDP; intrinsically disorder

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Ubiquitin C-Terminal Hydrolase L1 is required for regulated protein degradation through the ubiquitin proteasome system in kidney

Keywords: سیستم Ubiquitin-proteasome; immune-complex nephritis; proteasome abundance; ubiquitin-C-terminal hydrolase-L1; ubiquitin-proteasome system;

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2018 سفارش ترجمه

The physiological role of the free 20S proteasome in protein degradation: A critical review

Keywords: سیستم Ubiquitin-proteasome; Ubiquitin-proteasome system; Proteasomal complexes; Ubiquitin- and ATP-independent protein degradation;

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2018 سفارش ترجمه

Paradoxical effects of mutant ubiquitin on Aβ plaque formation in an Alzheimer mouse model

Keywords: سیستم Ubiquitin-proteasome; Mutant ubiquitin; Ubiquitin-proteasome system; γ-Secretase; Amyloid-β; Behavior; Alzheimer's disease;

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2018 سفارش ترجمه

PSMD2 regulates breast cancer cell proliferation and cell cycle progression by modulating p21 and p27 proteasomal degradation

Keywords: سیستم Ubiquitin-proteasome; Breast cancer; Ubiquitin-proteasome system; PSMD2; Cell cycle; p21; p27; BC; breast cancer; CI; confidence interval; DMFS; distant-metastasis-free survival; DUBs; deubiquitinating enzymes; E1s; Ub-activating enzymes; E2s; Ub-conjugating enzymes; E3s; Ub-p

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2018 سفارش ترجمه

Deubiquitylating enzymes as cancer stem cell therapeutics

Keywords: سیستم Ubiquitin-proteasome; Protein-IPSC; protein-induced pluripotent stem cells; CSCs; cancer stem cells; DUBs; deubiquitylating enzymes; ESCs; embryonic stem cells; PTMs; post-translational modifications; AML; acute myelogenous leukemia; USP/UBP; ubiquitin-specific processing prot

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2018 سفارش ترجمه

An herbal formula consisting of Schisandra chinensis (Turcz.) Baill, Lycium chinense Mill and Eucommia ulmoides Oliv alleviates disuse muscle atrophy in rats

Keywords: سیستم Ubiquitin-proteasome; Muscle atrophy; Traditional medicine; Synergy; Ubiquitin-proteasome system; C2C12;

دانلود رایگان متن کامل مقاله ISI 47 صفحه سال انتشار : 2018 سفارش ترجمه

Aberrant subcellular localization of SQSTM1/p62 contributes to increased vulnerability to proteotoxic stress recovery in Huntington's disease

Keywords: سیستم Ubiquitin-proteasome; ATF4; activating transcription factor 4; BSA; bovine serum albumin; CHX; cycloheximide; CQ; hydroxychloroquine; HD; Huntington's disease; HDAC6; histone deacetylase 6; Htt; huntingtin; mHtt; mutant huntingtin; Lamp1; lysosomal associated membrane protein

دانلود رایگان متن کامل مقاله ISI 48 صفحه سال انتشار : 2018 سفارش ترجمه

Identification of UBact, a ubiquitin-like protein, along with other homologous components of a conjugation system and the proteasome in different gram-negative bacteria

Keywords: سیستم Ubiquitin-proteasome; UBact; Ubiquitin; Pup; Proteasome; Bacteria; Dop; Deamidase of Pup; Mpa; mycobacterial proteasome ATPase; PafA; Proteasome accessory factor A; PPS; Pup-proteasome system; PrcA; proteasome subunit α; PrcB; proteasome subunit β; Pup; prokaryotic ubiquitin

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2017 سفارش ترجمه

Molecular chaperones of the Hsp70 family assist in the assembly of 20S proteasomes

Keywords: سیستم Ubiquitin-proteasome; Proteasome; Protein assembly; Molecular chaperone; Yeast; Heat shock protein; Hsp70; CP; core particle; RP; regulatory particle; UPS; ubiquitin-proteasome system; MCN; molecular chaperone network; ICAR; immobilized-cobalt affinity resin;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Orobol derivatives and extracts from Cudrania tricuspidata fruits protect against 6-hydroxydomamine-induced neuronal cell death by enhancing proteasome activity and the ubiquitin/proteasome-dependent degradation of α-synuclein and synphilin-1

Keywords: سیستم Ubiquitin-proteasome; 6-OHDA; 6-hydroxydomamine; PD; Parkinson's disease; PARP; poly (ADP-ribose) polymerase; ROS; reactive oxygen species; UPP; ubiquitin-proteasome pathway; UPS; ubiquitin-proteasome system; CTE50; 50% ethanol extract from Cudrania tricuspidata fruits; OB;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Normal human cell proteins that interact with the adenovirus type 5 E1B 55 kDa protein

Keywords: سیستم Ubiquitin-proteasome; Human adenovirus type 5 (HAdV-C5); E1B 55 kDa protein; Normal human cells; Mass spectrometry; Type I interferons; Ubiquitin-proteasome system; RNA metabolism;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

Mammalian target of rapamycin signaling and ubiquitin proteasome-related gene expression in 3 different skeletal muscles of colostrum- versus formula-fed calves

Keywords: سیستم Ubiquitin-proteasome; mammalian target of rapamycin; ubiquitin-proteasome system; muscle; neonatal calf;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

Simple and efficient knockdown of His-tagged proteins by ternary molecules consisting of a His-tag ligand, a ubiquitin ligase ligand, and a cell-penetrating peptide

Keywords: سیستم Ubiquitin-proteasome; Protein knockdown; His-tag-fused protein; Ubiquitin-proteasome system; Carrier peptide;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2017 سفارش ترجمه

Withaferin A induced impaired autophagy and unfolded protein response in human breast cancer cell-lines MCF-7 and MDA-MB-231

Keywords: سیستم Ubiquitin-proteasome; AO; Acridine orange; AVOs; Acidic vesicular organelles; CT; Chymotrypsin; LC3; Microtubule associated light chain 3; MDC; Mono-Dansyl-Cadaverine; UPS; Ubiquitin-proteasome system; WA; Withaferin A; WT; Wortmannin; EtBr; Ethidium Bromide; SQSTM1; Sequestos

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2017 سفارش ترجمه

UCHL1 Regulates Melanogenesis through Controlling MITF Stability in Human Melanocytes

Keywords: سیستم Ubiquitin-proteasome; DCT; dopachrome tautomerase; GFP; green fluorescent protein; MITF; microphthalmia-associated transcription factor; MNT-1; human melanoma cells; NHEM; normal human primary epidermal melanocyte; siRNA; small interfering RNA; TRP-1; tyrosinase-related protei

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2017 سفارش ترجمه

Postnatal Proteasome Inhibition Promotes Amyloid-β Aggregation in Hippocampus and Impairs Spatial Learning in Adult Mice

Keywords: سیستم Ubiquitin-proteasome; APP-CTFβ; amyloid precursor protein C-terminal fragments; EDTA; ethylenediaminetetraacetic acid; EGTA; (ethylene glycol-bis(β-aminoethyl ether)-N,N,N′,N′-tetraacetic acid; LTP; long-term potentiation; MVBs; multivesicular bodies; MWM; Morris water m

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2017 سفارش ترجمه

Structure and functions of the chaperone-like p97/CDC48 in plants

Keywords: سیستم Ubiquitin-proteasome; ADIN; antibody-dependent intracellular neutralization; ARF; ADP ribosylation factor; AAA + ATPase; ATPase associated with diverse cellular activities; CDC48; cell division cycle 48; CAD; chromatin associated degradation; ER; endoplasmic reticulum; ERAD;

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2017 سفارش ترجمه

The core ubiquitin system of mandarin fish, Siniperca chuatsi, can be utilized by infectious spleen and kidney necrosis virus

Keywords: سیستم Ubiquitin-proteasome; Ubiquitin-proteasome system; Mandarin fish; ISKNV; HECT E3; RING E3; Immune evasion;

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2017 سفارش ترجمه

UBE2S associated with OSCC proliferation by promotion of P21 degradation via the ubiquitin-proteasome system

Keywords: سیستم Ubiquitin-proteasome; APC/C; Cell cycle; G2/M arrest; Oral squamous cell carcinoma; P21; Ubiquitin-proteasome system;

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2017 سفارش ترجمه

Sub-cellular localization specific SUMOylation in the heart

Keywords: سیستم Ubiquitin-proteasome; AMPK; adenosine monophosphate-activated protein kinase; CAMKK; calcium-calmodulin-activated protein kinase kinase; CHIP; carboxyl terminus of HSP70-interacting protein; CVD; cardiovascular disease; cTnI; cardiac troponin I; d-flow; disturbed flow; DeSI; d

دانلود رایگان متن کامل مقاله ISI 76 صفحه سال انتشار : 2017 سفارش ترجمه

Targeting chaperones, heat shock factor-1, and unfolded protein response: Promising therapeutic approaches for neurodegenerative disorders

Keywords: سیستم Ubiquitin-proteasome; 17-AAG; 17-(allylamino)-17-demethoxygeldanamycin (tanespimycin); 17-DMAG; 17- dimethylaminoethylamino-17-demethoxygeldanamycin (alvespimycin); AAV; adeno-associated virus; Aβ; amyloid-β; AD; Alzheimer's disease; ALS; amyotrophic lateral sclerosis; APP;

دانلود رایگان متن کامل مقاله ISI 89 صفحه سال انتشار : 2017 سفارش ترجمه

The ubiquitination of serotonin transporter in lymphoblasts derived from fluvoxamine-resistant depression patients

Keywords: سیستم Ubiquitin-proteasome; MDD; major depressive disorder; SERT; serotonin transporter; MAGE-D1; melanoma antigen gene-D1; EBV; Epstein-Barr virus; HAM-D; Hamilton depression scale; UPS; ubiquitin-proteasome system; Major depressive disorder; Serotonin transporter; Ubiquitination

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

UBE2D2 is not involved in MuRF1-dependent muscle wasting during hindlimb suspension

Keywords: سیستم Ubiquitin-proteasome; UPS; ubiquitin proteasome system; HS; hindlimb suspension; MuRF1; muscle ring finger protein-1; UBE2D2; ubiquitin-conjugating enzyme E2 D2; UBE2B; ubiquitin-conjugating enzyme E2 B; MHC; myosin heavy chain; SPR; surface plasmon resonance; Y2H; yeast two-h

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

PEK-1 is crucial for hormesis induced by inhibition of the IRE-1/XBP-1 pathway in the Caenorhabditis elegans mev-1 mutant

Keywords: سیستم Ubiquitin-proteasome; Proteostasis; Unfolded protein response; Proteasome; Hormesis; Caenorhabditis elegans; ABU; activated in blocked unfolded protein response; ANOVA; analysis of variance; ATF-6; activating transcription factor 6; BiP; immunoglobulin binding protein; C. ele

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Mutants of collagen-specific molecular chaperone Hsp47 causing osteogenesis imperfecta are structurally unstable with weak binding affinity to collagen

Keywords: سیستم Ubiquitin-proteasome; Osteogenesis imperfecta; Collagen; Molecular chaperone Hsp47; Chemical chaperone; ER stress; ER; endoplasmic reticulum; OI; Osteogenesis imperfecta; UPS; ubiquitin-proteasome system; HMW; high molecular weight;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Arabidopsis Tóxicos en Levadura 78 (AtATL78) mediates ABA-dependent ROS signaling in response to drought stress

Keywords: سیستم Ubiquitin-proteasome; Ubiquitin-proteasome system (UPS); RING-type E3 ligase (RING); Drought stress; Reactive oxygen species (ROS); Arabidopsis Tóxicos en Levadura (ATL); ABA-dependent signaling; ATL; Arabidopsis Tóxicos en Levadura; UPS; Ubiquitin-Proteasome System; ROS; Re

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

On the linkage between the ubiquitin-proteasome system and the mitochondria

Keywords: سیستم Ubiquitin-proteasome; Ubiquitin-proteasome system; Mitochondria; Ubiquitination; Protein degradation; Proteasome; Protein–protein interactionSCUD, Saccharomyces cerevisiae ubiquitination database; GO, gene ontology; DUDE, database of ubiquitinating and deubiquitinating eznymes

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Baicalein inhibits α-synuclein oligomer formation and prevents progression of α-synuclein accumulation in a rotenone mouse model of Parkinson's disease

Keywords: سیستم Ubiquitin-proteasome; PD; Parkinson disease; α-syn; α-synuclein; SN; substantia nigra; LBs; Lewy bodies; PFA; paraformaldehyde; TH; tyrosine hydroxylase; PBS; phosphate buffered saline; ChAT; choline acetyltransferase; HPLC; high performance liquid chromatography; DA; dopami

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Cullin 5-RING E3 ubiquitin ligases, new therapeutic targets?

Keywords: سیستم Ubiquitin-proteasome; E3 ubiquitin ligase; Cullin RING ligase; Ubiquitin-proteasome system; Therapeutic targets; ASB; ankyrin repeat-containing proteins with a SOCS box; β-Trcp; β-transducin repeat-containing protein; BTB; bric-a-brac; CIS1; cytokine-inducible Src homology

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Atypical ubiquitination by E3 ligase WWP1 inhibits the proteasome-mediated degradation of mutant huntingtin

Keywords: سیستم Ubiquitin-proteasome; Huntington's disease; Huntingtin; WWP1; E3 ligase; Ubiquitin-proteasome system; Ubiquitination

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Hepatitis C virus core protein inhibits E6AP expression via DNA methylation to escape from ubiquitin-dependent proteasomal degradation

Keywords: سیستم Ubiquitin-proteasome; Core protein; DNA methylation; E6-associated protein; Hepatitis C virus; Ubiquitin-proteasome system;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Cardiac ubiquitin ligases: Their role in cardiac metabolism, autophagy, cardioprotection and therapeutic potential

Keywords: سیستم Ubiquitin-proteasome; ATG; autophagy-related gene; AMPK; AMP activated protein kinase; BECN1; beclin1; b-TrCP; beta-transducin repeat-containing protein; Cbl; Casitas B-lineage lymphoma; CHIP; Carboxyl terminus of Hsc70 interacting protein; CHMP2B; charged multivesicular body

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه