دانلود مقالات ISI درباره سیستم Ubiquitin-proteasome + ترجمه فارسی

Effects of slow-release urea and rumen-protected methionine and histidine on mammalian target of rapamycin (mTOR) signaling and ubiquitin proteasome-related gene expression in skeletal muscle of dairy cows

Keywords: سیستم Ubiquitin-proteasome; rumen-protected amino acid; mammalian target of rapamycin; ubiquitin-proteasome system; muscle; dairy cow;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

The ubiquitin-proteasome system is essential for the productive entry of Japanese encephalitis virus

Keywords: سیستم Ubiquitin-proteasome; Ubiquitin-proteasome system; Japanese encephalitis virus; Cellular trafficking; Productive entry; Lysosome; Ubiquitination;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Upregulation of MuRF1 and MAFbx participates to muscle wasting upon gentamicin-induced acute kidney injury

Keywords: سیستم Ubiquitin-proteasome; UPS; ubiquitin proteasome system; AKI; acute kidney injury; ATN; acute tubular necrosis; CKD; chronic kidney disease; MuRF1; muscle ring finger protein-1; MAFbx; muscle atrophy F-box protein; MUSA1; muscle ubiquitin ligase of the SCF complex in atrophy-1;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

The ubiquitin-proteasome system and autophagy: Coordinated and independent activities

Keywords: سیستم Ubiquitin-proteasome; Ubiquitin-Proteasome System; Autophagy;

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2016 سفارش ترجمه

TDP-43/FUS in motor neuron disease: Complexity and challenges

Keywords: سیستم Ubiquitin-proteasome; AD; Alzheimer's disease; Ago2; Argonaute 2; ALS; Amyotrophic lateral sclerosis; ALS/PD; amyotrophic lateral sclerosis and Parkinsonism-dementia complex; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; ATF3; activating transcription factor 3

دانلود رایگان متن کامل مقاله ISI 61 صفحه سال انتشار : 2016 سفارش ترجمه

Heat shock transcription factor δ32 is targeted for degradation via an ubiquitin-like protein ThiS in Escherichia coli

Keywords: سیستم Ubiquitin-proteasome; δ32; Escherichia coli; Ubiquitin-like protein; ThiS; IPTG; isopropyl-β-d-thiogalactoside; UPS; ubiquitin-proteasome system; UBLs; ubiquitin-like proteins; HSR; heat shock response; CBB; coomassie Brilliant Blue; Co-IP; Co-Immunoprecipitation.;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Cereblon is recruited to aggresome and shows cytoprotective effect against ubiquitin-proteasome system dysfunction

Keywords: سیستم Ubiquitin-proteasome; Intellectual disability; Cereblon; Aggresome; Cytoprotection; Ubiquitin-proteasome system;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

PUB22 and PUB23 U-BOX E3 ligases directly ubiquitinate RPN6, a 26S proteasome lid subunit, for subsequent degradation in Arabidopsis thaliana

Keywords: سیستم Ubiquitin-proteasome; U-BOX E3 ligase; Ubiquitin-proteasome system; Drought stress; RPN6; 26S proteasome lid complex; UPS; Ubiquitin-proteasome system; U-BOX; U-box-type E3 ligase; PUB22; Plant U-BOX protein 22; PUB23; Plant U-BOX protein 23;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Half-life of DISC1 protein and its pathological significance under hypoxia stress

Keywords: سیستم Ubiquitin-proteasome; Disrupted in schizophrenia 1 (DISC1); Hypoxia; Oxygen-glucose deprivation; Protein half-life; Ubiquitin-proteasome system;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Proinflammatory cytokines downregulate connexin 43-gap junctions via the ubiquitin-proteasome system in rat spinal astrocytes

Keywords: سیستم Ubiquitin-proteasome; Connexin 43; Astrocyte; Cytokine; Ubiquitin-proteasome system; Cycloheximide; Neuroinflammation;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Neuroprotective effect of modified Chungsimyeolda-tang, a traditional Korean herbal formula, via autophagy induction in models of Parkinson׳s disease

Keywords: سیستم Ubiquitin-proteasome; DG; modified Chungsimyeolda-tang; MYH; modified Youldahanso-tang; SCM; Sasang Constitutional Medicine; PD; Parkinson׳s disease; UPS; ubiquitin-proteasome system; ALP; autophagy-lysosomal pathway; MPP+; 1-methyl-4-phenylpyridinium; NGF; nerve growth facto

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Ascribing novel functions to the sarcomeric protein, myosin binding protein H (MyBPH) in cardiac sarcomere contraction

Keywords: سیستم Ubiquitin-proteasome; MyBPH; myosin binding protein H; cMyBPC; cardiac myosin binding protein C; LVH; left ventricular hypertrophy; HCM; hypertrophic cardiomyopathy; ALP; autophagy-lysosome pathway; AbA; Aureobasidin A; HIS3; imidazoleglycerolphosphate dehydratase; ADE2; phosp

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

Regulation of hippocampal synaptic plasticity by BDNF

Keywords: سیستم Ubiquitin-proteasome; 4E-BPs; eIF4E-binding proteins; 5-HT; 5-hydroxytryptamine; ADF; actin-depolymerising factor; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; AMPAR; AMPA receptors; Arc; activity-regulated cytoskeleton-associated protein; BDNF; brain-derived n

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2015 سفارش ترجمه

Autophagy in neurodegenerative diseases: From pathogenic dysfunction to therapeutic modulation

Keywords: سیستم Ubiquitin-proteasome; Aβ; amyloid beta; AD; Alzheimer's disease; ALS; amyotrophic lateral sclerosis; APP; amyloid precursor protein; ATP; adenosine triphosphate; Bci3; Bax cannel inhibitor 3; cAMP; cyclic adenosine monophosphate; CMA; chaperone-mediated autophagy; DLB; dement

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2015 سفارش ترجمه

Baclofen, a GABAB receptor agonist, enhances ubiquitin-proteasome system functioning and neuronal survival in Huntington's disease model mice

Keywords: سیستم Ubiquitin-proteasome; Huntington's disease; GABAB receptor agonist; Ubiquitin-proteasome system; Neuronal survival;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Influence of electrical stimulation on calpain and ubiquitin-proteasome systems in the denervated and unloaded rat tibialis anterior muscles

Keywords: سیستم Ubiquitin-proteasome; Rat; Electrical stimulation; Denervation; Unloading; Muscle atrophy; Calpain system; Ubiquitin-proteasome system

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Calcium channel blocker verapamil accelerates gambogic acid-induced cytotoxicity via enhancing proteasome inhibition and ROS generation

Keywords: سیستم Ubiquitin-proteasome; GA; gambogic acid; Ver; verapamil; Ab; antibody; ER; endoplasmic reticulum; ROS; reactive oxygen species; z-VAD-FMK; carbobenzoxy-valyl-alanyl-aspartyl-(O-methyl)-fluoromethylketone; CT-like; chymotrypsin-like; DCFH-DA; 2′,7′-dichlorfluorescein-diacet

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Ubiquitin-proteasome system and hereditary cardiomyopathies

Keywords: سیستم Ubiquitin-proteasome; Ubiquitin-proteasome system; Hypertrophic cardiomyopathy; Dilated cardiomyopathy;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

A calpain-cleaved fragment of β-catenin promotes BCRABL1 + cell survival evoked by autophagy induction in response to imatinib

Keywords: سیستم Ubiquitin-proteasome; ULK1; unc-51-like kinase; ATG; autophagy-related proteins; FIP200; focal adhesion interacting protein 200; PI3K; class III phosphoinositide 3-kinase; Vps; vacuolar protein sorting; LC3; microtubule-associated protein 1 light chain 3; PE; phosphatidylethan

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Role of the ubiquitin-proteasome system in cardiac dysfunction of adipose triglyceride lipase-deficient mice

Keywords: سیستم Ubiquitin-proteasome; ATF6; activating transcription factor 6; ATGL; adipose triglyceride lipase; AKO; adipose triglyceride lipase knockout; AMC; amino-4-methylcoumarin; CHOP; C/EBP homologous protein; EDTA; ethylenediaminetetraacetic acid; ER; endoplasmic reticulum; FA; fatty

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Bioactivity of Fragaria vesca leaves through inflammation, proteasome and autophagy modulation

Keywords: سیستم Ubiquitin-proteasome; Fragaria vesca leaves; Polyphenols; Inflammation; Nitric oxide scavenger; Ubiquitin-Proteasome system; Autophagy;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

SQSTM1 mutations - Bridging Paget disease of bone and ALS/FTLD

Keywords: سیستم Ubiquitin-proteasome; ALS; amyotrophic lateral sclerosis; aPKC; atypical protein kinase C; C9orf72; chromosome 9 open reading frame 72; FTD; frontotemporal dementia; FTLD; frontotemporal lobar degeneration; FUS/TLS; fused in sarcoma/translocated in liposarcoma; GWAS; genome-wi

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Functional characterization of Anaphase Promoting Complex/Cyclosome (APC/C) E3 ubiquitin ligases in tumorigenesis

Keywords: سیستم Ubiquitin-proteasome; APC/C; Anaphase Promoting Complex/Cyclosome; AOM; azoxymethane; Bub3; budding uninhibited by benzimidazole protein 3; BubR1; bub1-related protein; Cdc20; cell division cycle 20; Cdh1; Cdc20 homologue protein 1; DMBA; 7,12-dimethylbenz-α-anthracene; Emi1;

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2014 سفارش ترجمه

Histone deacetylase 6 regulates cytotoxic α-synuclein accumulation through induction of the heat shock response

Keywords: سیستم Ubiquitin-proteasome; Histone deacetylase 6; α-synuclein; Heat shock; Parkinson's disease; Ubiquitin-proteasome system;

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2014 سفارش ترجمه

Assembly of the 20S proteasome

Keywords: سیستم Ubiquitin-proteasome; Proteasome; Macromolecular complex assembly; Assembly factors; Proteolysis; Ubiquitin-proteasome system;

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2014 سفارش ترجمه

A new mechanism of RhoA ubiquitination and degradation: Roles of SCFFBXL19 E3 ligase and Erk2

Keywords: سیستم Ubiquitin-proteasome; Small GTPase protein; Protein stability; Ubiquitin-proteasome system; Phosphorylation; Cell proliferation; Stress fiber;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Dynamic regulation of endosymbiotic organelles by ubiquitination

Keywords: سیستم Ubiquitin-proteasome; chloroplasts; E3 ligases; mitochondria; plastids; ubiquitin-proteasome system

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

ERK5/BMK1 Is a Novel Target of the Tumor Suppressor VHL: Implication in Clear Cell Renal Carcinoma

Keywords: سیستم Ubiquitin-proteasome; ERK5/ERK5; extracellular signal-regulated kinase 5 (protein/gene); pVHL/VHL; von Hippel-Lindau protein/gene; CCRCC; clear cell renal cell carcinoma; HIF1α/HIF1α; hypoxia-inducible factor 1α (protein/gene); UPS; ubiquitin-proteasome system; DMOG; dimeth

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2013 سفارش ترجمه

Design and synthesis of estrogen receptor degradation inducer based on a protein knockdown strategy

Keywords: سیستم Ubiquitin-proteasome; Estrogen receptor; Protein knockdown; Tamoxifen; Ubiquitin-proteasome system

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2012 سفارش ترجمه

Protein degradation in DNA damage response

Keywords: سیستم Ubiquitin-proteasome; Ubiquitin-proteasome system; DNA damage response; Protein degradation; DNA repair; Checkpoint

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Involvement and interplay of Parkin, PINK1, and DJ1 in neurodegenerative and neuroinflammatory disorders

Keywords: سیستم Ubiquitin-proteasome; Aβ; amyloid-β; AD; Alzheimer's disease; AIMP2; aminoacyl tRNA synthetase complex-interacting multifunctional protein 2; CAA; cerebral amyloid angiopathy; CSF; cerebrospinal fluid; EAE; experimental autoimmune encephalomyelitis; ER; endoplasmic reticul

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

NIRF/UHRF2 occupies a central position in the cell cycle network and allows coupling with the epigenetic landscape

Keywords: سیستم Ubiquitin-proteasome; CAN gene; candidate cancer gene; CD; cluster of differentiation; CDK; cyclin-dependent kinase; COPA; cancer outlier profile analysis; DNMT; DNA methyltransferase; GRN; gene regulatory network; HDAC; histone deacetylase; H3K9; Histone H3 lysine 9; ICBP90;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2012 سفارش ترجمه

Dysfunction of constitutive and inducible ubiquitin-proteasome system in amyotrophic lateral sclerosis: Implication for protein aggregation and immune response

Keywords: سیستم Ubiquitin-proteasome; AD; Alzheimer's disease; ALS; amyotrophic lateral sclerosis; ARE; anti-oxidant responsive element; CHIP; carboxyl terminus of Hsc-70 interacting protein; cys; cysteine; CNS; central nervous system; DUB; deubiquitinating enzyme; D3T; dithiole-3-thione; EAE

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2012 سفارش ترجمه

CHIP E3 ligase regulates mammalian senescence by modulating the levels of oxidized proteins

Keywords: سیستم Ubiquitin-proteasome; CHIP; C-terminus of Hsp70-interacting protein; cpds; cumulative population doublings; E3; ubiquitin ligase enzyme; GFP; green fluorescent protein; MEFs; mouse embryonic fibroblasts; NAC; N-acetyl-cysteine; siRNA; small interfering RNA; UFD; ubiquitin fusi

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2011 سفارش ترجمه

Long-term aversive taste memory requires insular and amygdala protein degradation

Keywords: سیستم Ubiquitin-proteasome; Ubiquitin-proteasome system; Lactacystin; Memory updating; Insular cortex; Consolidation;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Damage-specific DNA binding protein 1 (DDB1) is involved in ubiquitin-mediated proteolysis of p27Kip1 in response to UV irradiation

Keywords: سیستم Ubiquitin-proteasome; Damage-specific DNA binding protein 1; UV irradiation; DNA damage; CDK inhibitor p27Kip1; E3-ubiquitin-ligase; DDB1/DDB2; damage-specific DNA binding protein 1/2; Skp2; S-phase kinase-associated protein 2; CUL4A; cullin 4A; CDK; cyclin-dependent kinase; G

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

The neuroprotective effect of modified Yeoldahanso-tang via autophagy enhancement in models of Parkinson's disease

Keywords: سیستم Ubiquitin-proteasome; Modified Youldahanso-tang (MYH); Neuroprotection; Autophagy; Parkinson's disease; 1-Methyl-4-phenyl-1,2,3,6-tetrahydrophenylpyridine (MPTP); Lactacystin; MYH; Modified Youldahanso-tang; PD; Parkinson's disease; UPS; ubiquitin-proteasome system; ALP; autop

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Macroautophagy and the proteasome are differently involved in the degradation of alpha-synuclein wild type and mutated A30P in an in vitro inducible model (PC12/TetOn)

Keywords: سیستم Ubiquitin-proteasome; alpha-synuclein; protein aggregation; macroautophagy; proteasome; oxidative stress; Parkinson's disease; CMA; chaperone-mediated autophagy; DOXY; doxycycline; FCS; fetal calf serum; HS; horse serum; LB; Lewy bodies; LDH; lactate dehydrogenase release to l

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Neuroprotective effects of MAPK/ERK1/2 and calpain inhibitors on lactacystin-induced cell damage in primary cortical neurons

Keywords: سیستم Ubiquitin-proteasome; AIF; apoptosis inducing factor; DIV; day in vitro; ERK1/2; extracellular signal-regulated kinase 1/2; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; GDNF; glia-derived neurotrophic factor; JNK; c-Jun N-terminal kinase; LC; lactacystin; LDH; lactate dehy

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2011 سفارش ترجمه

l-DOPA: A scapegoat for accelerated neurodegeneration in Parkinson's disease?

Keywords: سیستم Ubiquitin-proteasome; AADC; aromatic l-amino acid decarboxylase; ALDH; aldehyde dehydrogenase; AMPA; α-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate; AR; aldehyde reeductase; ATP; adenosine triphosphate; Bax; Bcl-2-associated X protein; BDNF; brain-derived neurotrophic fac

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2011 سفارش ترجمه

Preventing Ca2+-mediated nitrosative stress in neurodegenerative diseases: Possible pharmacological strategies

Keywords: سیستم Ubiquitin-proteasome; Reactive nitrogen species; S-Nitrosylation; Molecular chaperone; Ubiquitin-proteasome system; Protein misfolding; Mitochondrial fission; Neurodegeneration; Memantine

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Ventricular unloading is associated with increased 20s proteasome protein expression in the myocardium

Keywords: سیستم Ubiquitin-proteasome; ubiquitin-proteasome system; ventricular unloading; cell cycle; cardiac hypertrophy; circulating proteasome;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

In vitro treatments with ceftriaxone promote elimination of mutant glial fibrillary acidic protein and transcription down-regulation

Keywords: سیستم Ubiquitin-proteasome; GFAP, glial fibrillary acidic protein; GFP, green fluorescent protein; HSP27, heat shock protein 27; Cef, ceftriaxone; lact, lactacystinAlexander disease; Ceftriaxone; Glial fibrillary acidic protein; Small heat shock proteins; Ubiquitin-proteasome system

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2010 سفارش ترجمه

Programmed cell death-2 isoform1 is ubiquitinated by parkin and increased in the substantia nigra of patients with autosomal recessive Parkinson’s disease

Keywords: سیستم Ubiquitin-proteasome; Parkin; PDCD2-1; Apoptosis; Ubiquitin-proteasome system; Substantia nigra

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Autophagy and the ubiquitin-proteasome system: Collaborators in neuroprotection

Keywords: سیستم Ubiquitin-proteasome; Autophagy; Ubiquitin-proteasome system; Neurodegeneration; HDAC6; p62;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

Characterization of endogenous and recombinant human calpain-10

Keywords: سیستم Ubiquitin-proteasome; Calpain-10; Susceptibility gene for diabetes; Calpain-10 isoforms; Proteolytic activity; Radiolabeled oligopeptides; Random peptide library; ALLN; calpain inhibitor Ac-Leu-Leu-Nle-H; CAPN1; calpain-1 gene; CAPN10; calpain-10 gene; DMED; Dulbecco's Modifie

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

Ubiquitin-conjugating enzyme Cdc34 mediates cadmium resistance in budding yeast through ubiquitination of the transcription factor Met4

Keywords: سیستم Ubiquitin-proteasome; Cadmium; Resistance; Ubiquitin-proteasome system; Cdc34; Met 4; Sulfide formation

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

Proteasome inhibitor lactacystin disturbs the intracellular calcium homeostasis of dopamine neurons in ventral mesencephalic cultures

Keywords: سیستم Ubiquitin-proteasome; Ubiquitin-proteasome system; Lactacystin; Dopamine neuronal injury; Calcium homeostasis; L-type voltage dependent calcium channels

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

Highlights in experimental therapeutics

Keywords: سیستم Ubiquitin-proteasome; Telomerase; Telomere targeting agents; Heat shock protein 90; Geldanamycins; Ubiquitin-proteasome system; E3 ubiquitin ligase

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2007 سفارش ترجمه

Intragastric proteasome inhibition induces alpha-synuclein-immunopositive aggregations in neurons in the dorsal motor nucleus of the vagus in rats

Keywords: سیستم Ubiquitin-proteasome; Dorsal motor nucleus of the vagus; Proteasome inhibitor; Ubiquitin-proteasome system; Alpha-synuclein

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2006 سفارش ترجمه