Keywords: PTSD; Metabolomics; Glycomics; Clinical data; Animal models; Theranostic biomarkers; Patients; ACTH; adenocorticotropic hormone; APCI; atmospheric pressure chemical ionization; BDNF; brain derived neurotropic factor; CE; capillary electrophoresis; CE-MS;
مقالات ISI (ترجمه نشده)
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Keywords: ALT; alanine transaminase; AMH; anti-Müllerian hormone; AST; aspartate transaminase; ATP; adenosine triphosphate; DG; Duarte galactosemia; FSH; follicle-stimulating hormone; Gal-1-P; galactose-1-phosphate; GALE; UDP-galactose 4-epimerase; GALK; galactoki
Keywords: MS; mass-spectrometry; NMR; nuclear magnetic resonance spectroscopy; MRS; magnetic resonance spectroscopy; D-2-HG; D-2-hydroxyglutarate; α-KG; α-ketoglutarate; OAA; oxaloacetic acid; TET; ten-eleven translocation; GSH; glutathione; ROS; reactive oxygen
Keywords: SAR; structure-activity relationship; UDP-GlcNAc; UDP-N-acetylglucosamine; Peptidoglycan; MurA enzyme; Antibacterial agents; Quinazolinones;
Keywords: Peptidoglycan; Staphylococcus aureus; Metabolomics; Cell wall; Alr; Alanine racemase; ATCC; American Type Culture Collection; Ddl; D-Ala-D-Ala ligase; DMHA; N,N-dimethylhexylamine; LC-MS/MS; Liquid chromatography - tandem mass spectrometry; DAP; meso-Diam
Keywords: AD; Alzheimer's disease; CGE-LIF; capillary gel electrophoresis with laser-induced fluorescence detection; CMP-SA; cytidine monophosphate-sialic acid; Con A; concanavalin A; CSF; cerebrospinal fluid; DS; Down syndrome; DSA-FACE; DNA sequencer-assisted-flu
Keywords: GnRH neurons; Kisspeptin neurons; Female puberty; Chromatin modifications; DNA methylation; Transcriptional repression; Transcriptional activation; Epigenetic regulators; microRNAs; Long noncoding RNAs; 5hmC; 5-hydroxymethylcytosine; 5-mC; 5-methylcytosin
Keywords: Glycosaminoglycan; UDP-GlcUA; UDP-GlcNAc; AMPK; O-GlcNAcylation; HBP;
Keywords: Glycolysis; Isoenzymes; Cancer; Spliceforms; Anti-glycolytic agents; Bromopyruvate (PubChem CID: 70684); 2-deoxyglucose (PubChem CID: 9062); 3-PO (PubChem CID: 5720233); PGMI-004A (PubChem CID: 66521681); TEP-46 (Chem CID: 44246499); UDP-GlcNAc; uridine d
Keywords: NATs; natural antisense transcripts; IDC; intra erythrocytic developmental cycle; PFC; Plasmodium falciparum complicated samples; PFU; Plasmodium falciparum uncomplicated samples; HS-LAS; high sense and low antisense transcripts; HAS-LS; high antisense an
Keywords: ATP; adenosine-5â²-triphosphate; CI; chromosome instability; DEB; (±)-1,2:3,4-diepoxybutane; FA; Fanconi Anemia; FOM; fosfomycin; GSH; reduced glutathione; HD; healthy donors; ICL; interstrand crosslinks; IFAR; Fanconi Anemia Registry; MurA; enolpyruvyl
Keywords: Akt-GSK3β; Akt-Glycogen Synthase Kinase 3β; ALS; Amyotrophic Lateral Sclerosis; CCCP; Carbonyl cyanide m-chlorophenyl hydrazine; CMT; Charcot-Marie-Tooth; DA; Dopamine; DISC1; Disrupted In Schizophrenia 1; FEZ1; Fasciculation and Elongation Protein-
Functional significance of O-GlcNAc modification in regulating neuronal properties
Keywords: PTM; post-translational modification; OGT; O-GlcNAc transferase; OGA; O-GlcNAcase; O-GlcNAc; O-linked β-N-acetylglucosamine; UDP-GlcNAc; uridine diphosphate N-acetylglucosamine; GalNAc; N-acetylgalactosamine; Gal; galactose; PSD; postsynaptic density; NF
Modification of quaternary structure of Candida albicans GlcN-6-P synthase and its desensitization to inhibition by UDP-GlcNAc by site-directed mutagenesis
Keywords: Candida albicans; Glucosamine-6-phosphate synthase; Quaternary structure; UDP-GlcNAc; Site-directed mutagenesis; DTT; dithiothreitol; Fru-6-P; d-fructose-6-phosphate; GAH; glutamine amidohydrolase domain; GlcN-6-P; d-glucosamine-6-phosphate; ISOM; ketose/
Specific enzyme functionalities of Fusarium oxysporum compared to host plants
Keywords: Ap4A; diadenosine tetraphosphate; CAT; carnitine acetyltransferase; CDP-choline; cytidine diphosphate choline; CWDEs; cell walls degrading enzymes; DcpS; decapping scavenger enzyme; EC; enzyme commission numbers; HCCS; holocytochrome-c synthase; HGT; hori
Establishment of a five-enzyme cell-free cascade for the synthesis of uridine diphosphate N-acetylglucosamine
Keywords: ADP; adenosine diphosphate; ATP; adenosine triphosphate; BWM; bio wet mass; CMP-sialic; cytidine-5â²-monophospho-N-acetylneuraminic acid; FCC; flux control coefficient; GalU; bifunctional Glc-1P uridyltransferase; GDP; guanosine diphosphate; GlcNAc; N-
O-GlcNAcylation and neuronal energy status: Implications for Alzheimer's disease
Keywords: 3xTg-AD; triple transgenic mouse model of Alzheimer's disease; AD; Alzheimer's disease; AMPK; AMP-activated protein kinase; Asn; asparagine residue; ATP5A; ATP synthase subunit α; Aβ; amyloid-β peptide; AβPP; amyloid-β precursor protein; ER; endo
Synthesis and antimicrobial activity of 6-sulfo-6-deoxy-D-glucosamine and its derivatives
Keywords: cfu; colony forming units; GlcN; D-glucosamine; IPTG; isopropyl β-thiogalactoside; ISOM; isomerase domain of GlcN6P synthase; LB; Luria-Bertani; MIC; minimal inhibitory concentration; UDP-GlcNAc; uridine 5'-diphospho-N-acetyl-D-glucosamine;
Jaburetox affects gene expression and enzyme activities in Rhodnius prolixus, a Chagas' disease vector
Keywords: Jbtx; Jaburetox; CNS; central nervous system; NOS; nitric oxide synthase; SG; salivary glands; NO; nitric oxide; UAP; UDP-N-acetylglucosamine pyrophosphorylase; UDP-GlcNAc; UDP-N-acetylglucosamine; GPI; glycophosphatidylinositol; rUAP; recombinant UAP; AP
Theoretical pKa prediction of the α-phosphate moiety of uridine 5′-diphosphate-GlcNAc
Keywords: UDP-GlcNAc; OGT; Gaussian; pKa; Density functional theory; SMD;
Long range molecular dynamics study of interactions of the eukaryotic glucosamine-6-phosphate synthase with fructose-6-phosphate and UDP-GlcNAc
Keywords: GlcN-6-P synthase; glucosamine-6-phosphate synthase; Fru-6-P; fructose-6-phosphate; UDP-GlcNAc; uridine 5-diphospho N-acetylglucosamine; Glucosamine-6-phosphate synthase; UDP-GlcNAc; Molecular dynamics; Cosine content; Mobility analysis;
Engineered N-acetylhexosamine-active enzymes in glycoscience
Keywords: ATP; adenosine 5â²-triphosphate; CDP-GlcNAc; cytidine 5â²-diphospho-N-acetylglucosamine; CAZy; Carbohydrate-Active enZYmes; FAD; flavin adenine dinucleotide; Fuc; D-fucose; Gal; D-galactose; GH; glycoside hydrolase; GT; glycosyltransferase; GalNAc; N-ac
Glucosamine induces REDD1 to suppress insulin action in retinal Müller cells
Keywords: F6P; fructose 6-phosphate; HBP; Hexosamine Biosynthetic Pathway; GlcN6P; glucosamine-6-phosphate; GFAT; glutamine-fructose-6-phosphate amidotransferase; UDP-GlcNAc; UDP-N-acetylglucosamine; O-GlcNAc; O-GlcNAcylation; GAM; Glucosamine; VEGF; vascular endot
Resveratrol triggers ER stress-mediated apoptosis by disrupting N-linked glycosylation of proteins in ovarian cancer cells
Keywords: RSV; resveratrol; NLG; protein N-linked glycosylation; UPR; unfolded protein responses; ER; endoplasmic reticulum; G.F; glucose free media; TM; tunicamycin; PBMC; peripheral blood mononuclear cells; RBC; red blood cells; PERK; protein kinase RNA-like ER k
UDP-GlcNAc pathway: Potential target for inhibitor discovery against M. tuberculosis
Keywords: Drug resistance; GlmU; M. tuberculosis; Peptidoglycan; Target based screening; UDP-GlcNAc
O-GlcNAcylation is associated with the development and progression of gastric carcinoma
Keywords: HBP; hexosamine biosynthesis pathway; O-GlcNAc; O-linked β-N-acetylglucosamine; UDP-GlcNAc; uridine diphosphate N-acetylglucosamine; OGT; O-GlcNAc-transferase; OGA; O-GlcNAcase; GC; gastric carcinoma; EGC; early gastric carcinoma; AGC; advanced gastric c
AAV8-mediated expression of N-acetylglucosamine-1-phosphate transferase attenuates bone loss in a mouse model of mucolipidosis II
Keywords: UDP-GlcNAc; lysosomal enzyme GlcNAc-1-phosphotransferase; ML II; mucolipidoses II; KO; knock out; AAV; adeno-associated viral vector; BMD; bone mineral density; BMC; bone mineral content; IL-6; interleukin-6; Mucolipidosis II; Lysosomal disorder; N-acetyl
Characterizing non-hydrolyzing Neisseria meningitidis serogroup A UDP-N-acetylglucosamine (UDP-GlcNAc) 2-epimerase using UDP-N-acetylmannosamine (UDP-ManNAc) and derivatives
Keywords: Epimerization; Neisseria meningitidis; UDP-GlcNAc; UDP-ManNAc; UDP-GlcNAc 2-epimerase
A metabolic labeling approach for glycoproteomic analysis reveals altered glycoprotein expression upon GALNT3 knockdown in ovarian cancer cells
Keywords: EOC; epithelial ovarian cancer; PTM; post-translational modification; GALNT3; N-acetylgalactosaminyltransferase 3; GalNAc-Ts; GalNAc-transferases; KD; knockdown; shRNA; short hairpin RNA; siRNA; small interfering RNA; MUC1; mucin-1; Ac4GalNAz; peraceetyla
Mycelial development preceding basidioma formation in Moniliophthora perniciosa is associated to chitin, sugar and nutrient metabolism alterations involving autophagy
Keywords: CHIT; chitinase; CHS; chitin synthase; GH; glycosyl hydrolase; GT; glycosyl transferase; GlcNAc; β-1,4-N-acetylglucosamine; PAS; pre-autophagosomal structure; PCD; programmed cell death; UDP-GlcNAc; uridine diphosphate N-acetylglucosamine; Fungal develop
Probing the roles of conserved residues in uridyltransferase domain of Escherichia coli K12 GlmU by site-directed mutagenesis
Keywords: Uridyltransferase; UDP-GlcNAc; Substrate specificity; Site-directed mutagenesis
High-throughput screen identifies small molecule inhibitors targeting acetyltransferase activity of Mycobacterium tuberculosis GlmU
Keywords: UDP-GlcNAc; M. tuberculosis; GlmU; Rifampicin; Acetyltransferase; Drug resistant;
Identification of an N-acetylglucosamine kinase essential for UDP-N-acetylglucosamine salvage synthesis in Arabidopsis
Keywords: GlcNAc salvage pathway; Hexosamine pathway; N-Acetylglucosamine kinase; UDP-GlcNAc;
The dynamic metabolism of hyaluronan regulates the cytosolic concentration of UDP-GlcNAc
Keywords: Hyaluronan; O-GlcNAc transferase; Hyaluronan synthases; UDP-GlcNAc;
A microplate assay for the coupled transglycosylase-transpeptidase activity of the penicillin binding proteins; a vancomycin-neutralizing tripeptide combination prevents penicillin inhibition of peptidoglycan synthesis
Keywords: UDP-GlcNAc; UDP-N-acetyl glucosamine; UDP-MurNAc(pp); UDP-N-acetyl-muramylpentapeptide; TG; transglycosylase; TP; transpeptidase; V + T; vancomycin + neutralizing tripeptide; PBP; penicillin binding protein; UDP-MurNAc-(pp); UDP-N-acetyl-muramylpentap
A chemoenzymatic route to synthesize unnatural sugar nucleotides using a novel N-acetylglucosamine-1-phosphate pyrophosphorylase from Camphylobacter jejuni NCTC 11168
Keywords: N-Acetylglucosamine-1-phosphate pyrophosphorylase; Substrate specificity; UDP-GlcNAc; Unnatural sugar nucleotide; Chemoenzymatic synthesis;
E. coli sabotages the in vivo production of O-linked β-N-acetylglucosamine-modified proteins
Keywords: O-GlcNAc; O-linked β-N-acetylglucosamine; NagZ; E. coli β-N-acetylglucosaminidase; OGT; O-GlcNAc transferase; OGA; O-GlcNAcase; UDP-GlcNAc; uridine 5â²-diphospho-N-acetylglucosamine; CREB1; human cAMP responsive element-binding protein; Q2; second glut
Roles of the nucleotide sugar transporters (SLC35 family) in health and disease
Keywords: CST; CMP-sialic acid transporter; GFT; GDP-fucose transporter; UGT; UDP-galactose transporter; UDP-GlcNAc; UDP-N-acetylglucosamine; UDP-GalNAc; UDP-N-acetylgalactosamine; UDP-GlcA; UDP-glucuronic acid; ENTPD; ectonucleoside triphosphate diphosphohydrolase
Revealing natural antisense transcripts from Plasmodium vivax isolates: Evidence of genome regulation in complicated malaria
Keywords: GLC; glucose; G-6-P; glucose-6-phosphate; F-6-P; fructose-6-phosphate; FBP; fructose 1,6-bis phosphate; DHAP; dihydroxy-acetone-phosphate; GAP; glyceraldehyde 3-phosphate; 1,3 BPG; 1,3-biphosphoglycerate; 3PG; 3-phosphoglycerate; 2PG; 2-phophoglycerate; P
β-Glucan administration to diabetic rats alleviates oxidative stress by lowering hyperglycaemia, decreasing non-enzymatic glycation and protein O-GlcNAcylation
Keywords: AGE; advanced glycation end product; BGEE; β-glucan-enriched extract; BSA; bovine serum albumin; CAT; catalase; D; diabetic animal group; ND; non-diabetic animal group; HBP; hexosamine biosynthetic pathway; i.p.; intraperitoneal; O-GlcNAc; O-linked N-ace
Characterization of O-GlcNAc cycling and proteomic identification of differentially O-GlcNAcylated proteins during G1/S transition
Keywords: CDK; Cyclin dependent kinase; CHX; Cycloheximide; CK; Cytokeratin; hnRNP; Heterogeneous nuclear ribonucleoprotein; HU; Hydroxyurea; MCM; Minichromosome maintenance; O-GlcNAc; O-linked beta-N-acetylglucosaminylation; OGA; O-GlcNAcase or beta-N-acetylglucos
Altered cofactor binding affects stability and activity of human UDP-galactose 4â²-epimerase: Implications for type III galactosemia
Keywords: ANS; 1-anilinonaphthalene-8-sulphonic acid; BS3; suberic acid bis(3-sulfo-N-hydroxysuccinimide ester); Gal-1P; galactose 1-phosphate; Glc-1P; glucose 1-phopshate; GALE; UDP-galactose 4â²-epimerase; GuHCl; guanidine hydrochloride; hGALE; human GALE; FRET;
N- and O-linked glycosylation of total plasma glycoproteins in galactosemia
Keywords: AMH; anti-Müllerian hormone; DHB; 2, 5-dihydroxybenzoic acid; DMSO; dimethyl sulfoxide; GALE; UDP-galactose 4â²-epimerase; GALT; galactose-1-phosphate uridylyltransferase; UDP-Gal; uridine diphosphate galactose; UDP-GalNAc; uridine diphosphate-N-acetyl-
Enzymatic synthesis and properties of uridine-5â²-O-(2-thiodiphospho)-N-acetylglucosamine
Keywords: Enzymatic synthesis; UDP-GlcNAc; Glycosylation; SAMDI MS;
Structure and synthesis of polyisoprenoids used in N-glycosylation across the three domains of life
Keywords: LLO; lipid-linked oligosaccharide; OST; oligosaccharide transferase; IPP; isopentenyl pyrophosphate; DMAPP; dimethylallyl pyrophosphate; MVA; mevalonate; DOXP; 1-deoxy-D-xylulose-5-phosphate; HMG-CoA; 3-hydroxy-3methylglutaryl-CoA; HMGS; HMG-CoA synthase;
A convenient synthesis of the C-1-phosphonate analogue of UDP-GlcNAc and its evaluation as an inhibitor of O-linked GlcNAc transferase (OGT)
Keywords: O-GlcNAc transferase; N-Acetylglucosamine; UDP-GlcNAc; Phosphate isostere; OGT inhibition
The role of GlcNAc in formation and function of extracellular matrices
Keywords: GlcNAc; UDP-GlcNAc; Glycobiology; Extracellular matrix; Glycosyltransferase; Drosophila; Human disease
Glucose-6-phosphate as a probe for the glucosamine-6-phosphate N-acetyltransferase Michaelis complex
Keywords: Crystal structure; Michaelis complex; Acetyltransferase; UDP-GlcNAc; Kinetics; Inhibitor
Hsp70-GlcNAc-binding activity is released by stress, proteasome inhibition, and protein misfolding
Keywords: Hsp70; Stress; O-GlcNAc; UDP-GlcNAc; Energy charge; Proteasome inhibition; Amino-acid analogue;
A novel β1,3-N-acetylglucosaminyltransferase (β3Gn-T8), which synthesizes poly-N-acetyllactosamine, is dramatically upregulated in colon cancer
Keywords: β3Gn-T, UDP-GlcNAc: β-galactose β1,3-N-acetylglucosaminyltransferase; β3Gal-T, UDP-galactose: β-N-acetylglucosamine β1,3-galactosyltransferase; β3GalNAc-T, UDP-GalNAc: β-galactose β1,3-N-acetylgalactosaminyltransferase; UDP-GlcNAc; uridine diphos