دانلود مقالات ISI درباره Vegfr + ترجمه فارسی

Regulation of human thyroid follicular cell function by inhibition of vascular endothelial growth factor receptor signalling

Keywords: VEGF; VEGFR; VEGFR inhibitors; Thyroid; Plasminogen activators; 125I uptake;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Inherent propensity of amnion-derived mesenchymal stem cells towards endothelial lineage: Vascularization from an avascular tissue

Keywords: Angiogenesis; Mesenchymal stem cells; Endothelial lineage; Amniotic membrane; Oct4; Octamer binding factor 4; Sox2; sex determining region Y-box 2; SSEA; Stage specific embryonic antigen; Klf4; Kruppel-like factor; RT-PCR; Reverse transcriptase polymerase

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Synthesis, in silico, in vitro, and in vivo investigation of 5-[11C]methoxy-substituted sunitinib, a tyrosine kinase inhibitor of VEGFR-2

Keywords: Sunitinib®; VEGFR; Docking; Molecular dynamics; MM-GBSA; Carbon-11; Radiolabeling

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Blocking αvβ3 integrin by a recombinant RGD disintegrin impairs VEGF signaling in endothelial cells

Keywords: Disintegrin; Integrin; VEGF; VEGFR; Cell adhesion; MMP; Tumor microenvironment;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

A preclinical and clinical review of aflibercept for the management of cancer

Keywords: Aflibercept; Angiogenesis; Bevacizumab; Clinical trial; Review; Safety; Vascular endothelial growth factor; VEGF-Trap; VEGFR

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

S100B-RAGE dependent VEGF secretion by cardiac myocytes induces myofibroblast proliferation

Keywords: VEGF; vascular endothelial growth factor; VEGFR; vascular endothelial growth receptor; LUX; luciferase; αSMA; α smooth muscle actin; SMMHC; smooth muscle myosin heavy chain; RAGE; receptor for advanced glycation end products; MAPK; mitogen activated kin

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Combining the Multitargeted Tyrosine Kinase Inhibitor Vandetanib with the Antiestrogen Fulvestrant Enhances Its Antitumor Effect in Non-small Cell Lung Cancer

Keywords: EGFR; Estrogen; NSCLC; VEGF; VEGFR; Tyrosine kinase inhibitor;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Progress of molecular targeted therapies for prostate cancers

Keywords: Prostate cancer; EGFR; IGF-1R; VEGFR; Androgen; Hormone resistant

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2012 سفارش ترجمه

Research ArticleAssociation of the hemochromatosis gene with pazopanib-induced transaminase elevation in renal cell carcinoma

Keywords: VEGFR; vascular endothelial growth factor receptor; RCC; renal cell carcinoma; ALT; alanine aminotransferase; ULN; upper limit of the normal range; HLA; human leukocytic antigen; DILI; drug-induced liver injury; CC; case-control; QTA; quantitative trait

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Multitargeted receptor tyrosine kinase inhibition: An antiangiogenic strategy in non-small cell lung cancer

Keywords: Angiogenesis; NSCLC; TKIs; VEGFR; PDGFR; FGFR;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Phase 2 Trial of Linifanib (ABT-869) in Patients with Advanced Non-small Cell Lung Cancer

Keywords: Angiogenesis; Linifanib (ABT-869); NSCLC; PDGFR; VEGFR

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Characterization and functional elucidation of a fucosylated 1,6-α-d-mannogalactan polysaccharide from Antrodia cinnamomea

Keywords: Antrodia cinnamomea; Polysaccharide; Mannogalactan; Angiogenesis; Angiopoietin-2; VEGFR

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Phase 2 trial of linifanib (ABT-869) in patients with advanced renal cell cancer after sunitinib failure

Keywords: Renal cell carcinoma; Sunitinib; ABT-869; VEGFR; Angiogenesis inhibitors;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Biochemical characterization of a novel type-II VEGFR2 kinase inhibitor: Comparison of binding to non-phosphorylated and phosphorylated VEGFR2

Keywords: IC50; 50% inhibitory concentration; ATP; adenosine 5′-triphosphate; DMSO; dimethyl sulfoxide; DTT; dl-dithiothreitol; EDTA; ethylenediamine-N,N,N′,N′-tetraacetic acid; MgCl2; magnesium chloride; MnCl2; manganese chloride; Tris; tris(hydroxymethyl)am

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Research ArticleNeuropilin-1 is upregulated in hepatocellular carcinoma and contributes to tumour growth and vascular remodelling

Keywords: HCC; hepatocellular carcinoma; VEGF; vascular endothelial growth factor; VEGFR; vascular endothelial growth factor receptor; NRP1; neuropilin-1; HGF; hepatocyte growth factor; PDGF-B; platelet-derived growth factor-B; LSEC; liver sinusoidal endothelial ce

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Induction of LYVE-1/stabilin-2-positive liver sinusoidal endothelial-like cells from embryoid bodies by modulation of adrenomedullin-RAMP2 signaling

Keywords: ESCs; Embryonic stem cells; EBs; Embryoid bodies; Ac-LDL; Acetylated low-density lipoprotein; AM; Adrenomedullin; RAMP; Receptor activity-modifying protein; CRLR; Calcitonin receptor-like receptor; GPCR; G protein-coupled receptor; TGFβ; Transforming gro

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

Novel Therapeutic Targets in Non-small Cell Lung Cancer

Keywords: Non-small cell lung cancer; Molecular target; Mutation; EGFR; VEGF; VEGFR; KRAS; BRAF; PIK3CA; EML4-ALK; IGF-1R

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2011 سفارش ترجمه

Use of DNA Microarray and Small Animal Positron Emission Tomography in Preclinical Drug Evaluation of RAF265, a Novel B-Raf/VEGFR-2 Inhibitor

Keywords: CT; computed tomography; FDG; 2′-deoxy-2′-[18F]fluoro-D-glucose; FLT; 3′-deoxy-3′-[18F]fluorothymidine; H&E; hematoxylin and eosin; %ID/g; percent injected dose per gram; PEG; polyethylene glycol; PET; positron emission tomography; ROI; region of

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2011 سفارش ترجمه

Macitentan (ACT-064992), a Tissue-Targeting Endothelin Receptor Antagonist, Enhances Therapeutic Efficacy of Paclitaxel by Modulating Survival Pathways in Orthotopic Models of Metastatic Human Ovarian Cancer

Keywords: ET; endothelin; ETR; endothelin receptor; ETAR; endothelin A receptor; ETBR; endothelin B receptor; PBS; phosphate-buffered saline; VEGFR; vascular endothelial growth factor receptor;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2011 سفارش ترجمه

Inhibition of experimental choroidal neovascularization in mice by anti-VEGFA/VEGFR2 or non-specific siRNA

Keywords: mouse model; choroidal neovascularization; siRNA; VEGFA; VEGFR

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

An online coupled cell membrane chromatography with LC/MS method for screening compounds from Aconitum carmichaeli Debx. acting on VEGFR-2

Keywords: Cell membrane chromatography; High performance liquid chromatography mass spectrometry; Online analysis; VEGFR; Aconitum carmichaeli Debx

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Vascular endothelial growth factor (VEGF)-A: Role on cardiac angiogenesis following myocardial infarction

Keywords: Myocardial infarction; Angiogenesis; VEGF-A; VEGFR

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Phase 1 Study of Combination Treatment with PTK 787/ZK 222584 and Cetuximab for Patients with Advanced Solid Tumors: Safety, Pharmacokinetics, Pharmacodynamics Analysis

Keywords: AE; adverse event; AUC0-24; area under the curve 0 to 24 hours; CE(P)C; circulating endothelial (progenitor) cells; Cmax; maximum observed plasma concentration; CTCAE; Common Terminology Criteria for Adverse Events; DLT; dose-limiting toxicity; EGFR; epid

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Vascular Endothelial Growth Factor Receptor Tyrosine Kinase Inhibitors in Non-Small-Cell Lung Cancer

Keywords: Antiangiogenesis; Axitinib; BIBF 1120; Cediranib; Dose-finding study; Metastatic NSCLC; Motesanib; Pazopanib; PDGFR; Sorafenib; Sunitinib; Vandetanib; Vatalanib; VEGFR; XL647; XL999;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

TSU-16, (Z)-3-[(2,4-dimethylpyrrol-5-yl)methylidenyl]-2-indolinone, is a potent activator of aryl hydrocarbon receptor and increases CYP1A1 and CYP1A2 expression in human hepatocytes

Keywords: VEGF; vascular endothelial growth factor; VEGFR; vascular endothelial growth factor receptor; TSU-16; (Z)-3-[(2,4-dimethylpyrrol-5-yl)methylidenyl]-2-indolinone; CYP; cytochrome P450; AhR; aryl hydrocarbon receptor; OMP; omeprazole; 3MC; 3-methylcholanthr

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Research ArticleAZD6244 enhances the anti-tumor activity of sorafenib in ectopic and orthotopic models of human hepatocellular carcinoma (HCC)

Keywords: HCC xenografts; Combined therapy; Growth inhibition; Angiogenesis; Apoptosis; HCC; hepatocellular carcinoma; VEGFR; vascular endothelial growth factor receptor; PDGFR; platelet-derived growth factor receptor; MEK; mitogen-activated protein kinase; ERK; ex

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Liver cancer: From molecular pathogenesis to new therapies

Keywords: DEB; drug-eluting bead; HBV; hepatitis B virus; HCC; hepatocellular carcinoma; HCV; hepatitis C virus; hTERT; human telomerase reverse transcriptase; PDGF; platelet derived growth factor; FAK; focal adhesion kinase; Pyk2; proline-rich tyrosine kinase 2; M

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Design, synthesis and evaluation of 2-amino-4-m-bromoanilino-6-arylmethyl-7H-pyrrolo[2,3-d]pyrimidines as tyrosine kinase inhibitors and antiangiogenic agents1

Keywords: RTKs; receptor tyrosine kinases; PDGFR; platelet-derived growth factor receptor; FGFR; fibroblast growth factor receptor; IGFR; insulin growth factor receptor; VEGFR; vascular endothelial growth factor receptor; EGFR; epidermal growth factor receptor; CAM

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2010 سفارش ترجمه

N-Phenyl-N′-[4-(5H-pyrrolo[3,2-d]pyrimidin-4-yloxy)phenyl]ureas as novel inhibitors of VEGFR and FGFR kinases

Keywords: VEGFR; FGFR; Pyrrolo[3,2-d]pyrimidine; Urea

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2010 سفارش ترجمه

Design, synthesis, and evaluation of 5-methyl-4-phenoxy-5H-pyrrolo[3,2-d]pyrimidine derivatives: Novel VEGFR2 kinase inhibitors binding to inactive kinase conformation

Keywords: VEGFR; Type-II inhibitor; Pyrrolo[3,2-d]pyrimidine; diphenylurea

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2010 سفارش ترجمه

Angiogenesis and Current Antiangiogenic Strategies for the Treatment of Cancer

Keywords: bFGF; basic fibroblast growth factor; DLL4; Notch ligand delta-like 4; ERK; extracellular signal-regulated kinase; FDA; Food and Drug Administration; HIF; hypoxia-inducible factor; MAPK; mitogen-activated protein kinase; MMP; matrix metalloproteinase; m

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2010 سفارش ترجمه

ERK1/2-Dependent Vascular Endothelial Growth Factor Signaling Sustains Cyst Growth in Polycystin-2 Defective Mice

Keywords: ADPKD; autosomal dominant polycystic kidney disease; CC3; cleaved caspase-3; DMOG; 2-oxoglutarate analogues dimethyloxaloylglycine; ERK; extracellular signal-regulated kinase; HIF; hypoxia-inducible factor; MEK; mitogen signal-regulated kinase; PC1; pol

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2010 سفارش ترجمه

A specific vascular endothelial growth factor receptor tyrosine kinase inhibitor enhances the antiproliferative effect of trastuzumab in human epidermal growth factor receptor 2 overexpressing breast cancer cell lines

Keywords: Trastuzumab; HER-2; VEGFR; Breast cancer

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

The VEGF-system in primary pulmonary angiosarcomas and haemangioendotheliomas: New potential therapeutic targets?

Keywords: Pulmonary angiosarcomas; Pulmonary haemangioendotheliomas; VEGF; VEGFR; Tie2; Immunohistochemistry; Mesenchymal tumors

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Pharmacophore and docking-based combined in-silico study of KDR inhibitors

Keywords: 3D-QSAR; Drug design; Pharmacophore; Docking; CoMFA; CoMSIA; VEGFR

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

VEGFR1 receptor tyrosine kinase localization to the Golgi apparatus is calcium-dependent

Keywords: VEGF-A; Vascular endothelial growth factor A; VEGFR; Vascular endothelial growth factor receptor; PLCγ1; Phospholipase Cγ1; TGN46; trans-Golgi network protein 46 kDa; GalT; β1,4-galactosyltransferase; MannII; mannosidase II; GM130; Golgi matrix protein

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2009 سفارش ترجمه

Vascular endothelial growth factors synthesized by human lung mast cells exert angiogenic effects

Keywords: Human mast cells; vascular endothelial growth factors; vascular endothelial growth factor receptors; angiogenesis; prostaglandin E2; adenosine; chemotaxis; CAM; Chorioallantoic membrane; CBMC; Cord blood-derived mast cell; GAPDH; Glyceraldehyde-3-phosph

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2009 سفارش ترجمه

VEGF-A Links Angiogenesis and Inflammation in Inflammatory Bowel Disease Pathogenesis

Keywords: CD; Crohn's disease; CAM; cell adhesion molecules; HIMEC; human intestinal microvascular endothelial cell; ICAM; intercellular adhesion molecule; UC; ulcerative colitis; VCAM; vascular cellular adhesion molecule; VEGF-A; vascular endothelial growth factor

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2009 سفارش ترجمه

PET Imaging of Angiogenesis

Keywords: Angiogenesis; Molecular imaging; Integrin; VEGFR; MMP

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2009 سفارش ترجمه

Sorafenib in Lung Cancer: Clinical Developments and Future Directions

Keywords: NSCLC; TKI; Proangiogenic; VEGFR; Raf kinase;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2008 سفارش ترجمه

Discovery of indenopyrazoles as EGFR and VEGFR-2 tyrosine kinase inhibitors by in silico high-throughput screening

Keywords: In silico screening; EGFR; VEGFR; Tyrosine kinase inhibitor; Indenopyrazoles

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2008 سفارش ترجمه

Ranibizumab Combined With Low-Dose Sorafenib for Exudative Age-Related Macular Degeneration

Keywords: AMD; age-related macular degeneration; IC50; 50% inhibitory concentration; OCT; optical coherence tomography; PED; pigment epithelial detachment; VEGF; vascular endothelial growth factor; VEGFR; VEGF receptor;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2008 سفارش ترجمه

The Current Status and Evolving Role of Sunitinib in Non-small Cell Lung Cancer

Keywords: VEGFR; PDGF; Receptor tyrosine kinase inhibitor;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2008 سفارش ترجمه

Traditional Chinese drug ShuXueTong facilitates angiogenesis during wound healing following traumatic brain injury

Keywords: TCM, traditional Chinese medicine; PBS, phosphate buffered saline; MVC, microvessel count; VEGF, vascular endothelial growth factor; PVDF, polyvinylidene difluoride; HRP, horseradish peroxidase; RT, room temperature; ECL, enhanced chemiluminescence; VEGFR

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2008 سفارش ترجمه

Scaffold oriented synthesis. Part 2: Design, synthesis and biological evaluation of pyrimido-diazepines as receptor tyrosine kinase inhibitors

Keywords: KDR inhibitors; VEGFR; PDGFR; cKit inhibitors; Flt3 inhibitors; Adenine mimics; Structure-based drug design

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2008 سفارش ترجمه

Celastrol inhibits the growth of human glioma xenografts in nude mice through suppressing VEGFR expression

Keywords: Celastrol; Antiangiogenesis; VEGFR; Glioma; VEGF

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

Effective delivery of an angiogenesis inhibitor by neovessel-targeted liposomes

Keywords: APRPG-PEG-Lip-SU1498; APRPG-PEG-modified liposomal SU1498; DDS; drug delivery systems; DPPC; dipalmitoylphosphatidylcholine; DPPG; dipalmitoylphosphatidylglycerol; DSPE-PEG-APRPG; distearoylphosphatidylethanolamine-polyethyleneglycol-APRPG peptide conjuga

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

SU11248 (Sunitinib) Sensitizes Pancreatic Cancer to the Cytotoxic Effects of Ionizing Radiation

Keywords: Pancreatic cancer; Sunitinib; SU11248; Radiosensitizer; VEGFR; PDGFR;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

A Randomized, Double-Blind, Phase IIa Dose-Finding Study of Vandetanib (ZD6474) in Japanese Patients With Non-Small Cell Lung Cancer

Keywords: Non-small cell lung cancer; Vandetanib; EGFR; VEGFR

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Heterotypic contact reveals a COX-2-mediated suppression of osteoblast differentiation by endothelial cells: A negative modulatory role for prostanoids in VEGF-mediated cell: cell communication?

Keywords: VEGF; VEGFR; PGE2; COX-2; Osteoblast; Endothelial cell; Cell proliferation; Cell differentiation; Cell: cell communication

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه