دانلود مقالات ISI درباره Vegfr + ترجمه فارسی

Molecularly targeted anti-cancer drugs inhibit the invasion and metastasis of hepatocellular carcinoma by regulating the expression of MMP and TIMP gene families

Keywords: Hepatocellular carcinoma; Sorafenib; Regorafenib; Levnatinib; Invasion; Metastasis; Hepatocellular carcinoma; HCC; Matrix metalloproteinases; MMPs; Tissue inhibitors of MMPs; TIMPs; Extracellular matrix; ECM; Receptor tyrosine kinases; RTKs; Vascular endo

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2018 سفارش ترجمه

Assessment and management of diarrhea following VEGF receptor TKI treatment in patients with ovarian cancer

Keywords: Ovarian cancer; Diarrhea; VEGF receptor tyrosine kinase inhibitor; VEGF; VEGFR; TKI;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2018 سفارش ترجمه

Antiangiogenic therapy for patients with aggressive or refractory advanced non-small cell lung cancer in the second-line setting

Keywords: CI; confidence interval; DCR; disease control rate; DOC; docetaxel; EMA; European Medicines Agency; FDA; US Food and Drug Administration; HR; hazard ratio; ITT; intent to treat; NSCLC; non-small cell lung cancer; OR; odds ratio; ORR; objective response ra

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

Differential angiogenic activities of naringin and naringenin in zebrafish in vivo and human umbilical vein endothelial cells in vitro

Keywords: CVD; cardiovascular diseases; DA; dorsal aorta; ECGS; endothelial cell growth supplement; EGFP; enhanced green fluorescent protein; F-12K; Kaighn's modification of Han's F12 medium; hpf; hours post fertilization; hpt; hours post treatment; HUVEC; huma

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

Multitargeted kinase inhibitors imatinib, sorafenib and sunitinib perturb energy metabolism and cause cytotoxicity to cultured C2C12 skeletal muscle derived myotubes

Keywords: Mitochondria; Complex activities; C2C12 cells; Cytotoxicity; Tyrosine kinase inhibitors; Glucose and nucleoside uptake; BCR; breakpoint cluster region; ABL; Abelson murine leukemia; PDGFR; platelet derived growth factor receptor; VEGFR; vascular endotheli

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Light-enhanced VEGF121/rGel: A tumor targeted modality with vascular and immune-mediated efficacy

Keywords: Vascular targeting; Immune mediated cell death; Targeted toxin; Photochemical internalization; VEGFR;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

NF-κB pathways in the development and progression of colorectal cancer

Keywords: 5-FU; 5-fluorouracil; AMPK/mTOR; AMP-activated Protein Kinase/mammalian target of rapamycin; APC; adenomatous polyposis coli; BAFF; B-cell activating factor; COX-2; cyclooxygenase 2; CRC; Colorectal cancer; DD; Dimerization domain; EGFR; epidermal growth

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2018 سفارش ترجمه

Design, synthesis and biological evaluation of a series of novel 2-benzamide-4-(6-oxy-N-methyl-1-naphthamide)-pyridine derivatives as potent fibroblast growth factor receptor (FGFR) inhibitors

Keywords: FGFR; VEGFR; Synergistic effect; Tumor growth inhibition; Lucitanib;

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2018 سفارش ترجمه

High throughput routine determination of 17 tyrosine kinase inhibitors by LC-MS/MS

Keywords: ALL; Acute Lymphoid Leukemia; CML; Chronic Myeloid Leukaemia; CV; Coefficient of Variation; EGFR; Endothelial derived growth factor Receptor; EMA; European Medicines Agency; ER; Extraction Recovery; FDA; Food and Drug Administration; GIST; Gastro Intestin

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2018 سفارش ترجمه

Intravitreal implantable magnetic micropump for on-demand VEGFR-targeted drug delivery

Keywords: Drug delivery; On-demand; Magnetic micropump; VEGFR; Gold nanoparticle;

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2018 سفارش ترجمه

LW-215, a newly synthesized flavonoid, exhibits potent anti-angiogenic activity in vitro and in vivo

Keywords: HUVECs; human umbilical vein endothelial cells; CAM; chicken chorioallantoic membrane; VEGFR; vascular endothelial growth factor receptor; MAPK; mitogen-activated protein kinase; ERK; extracellular signal-regulated kinase; DMSO; dimethyl sulfoxide; LW-215

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2018 سفارش ترجمه

MiR-128-3p directly targets VEGFC/VEGFR3 to modulate the proliferation of lymphatic endothelial cells through Ca2+ signaling

Keywords: LECs; lymphatic endothelial cell; VEGF; vascular endothelial growth factor; VEGFR; vascular endothelial growth factor receptor; HUVECs; human umbilical vein endothelial cells; NAADP; nicotinic acid adenine dinucleotide phosphate; BrdU; 5-bromo-2-deoxyUrid

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2018 سفارش ترجمه

New insights in the structure-activity relationships of 2-phenylamino-substituted benzothiopyrano[4,3-d]pyrimidines as kinase inhibitors

Keywords: Benzothiopyranopyrimidines; KDR kinase; Antiproliferative activity; Kinase inhibitors; A-431; epidermoid carcinoma cell line; DMEDA; N,N′-dimethylethylendiamine; HeLa; cervix adenocarcinoma cell line; h; human; HUVEC; human umbilical vein endothelial ce

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2018 سفارش ترجمه

A partnership with the proteasome; the destructive nature of GSK3

Keywords: AMPK; AMP-activated protein kinase; ARE; antioxidant response element; β-TrCP; beta-transducin repeat containing protein; CKI; casein kinase-1; CHD; chromatin helicase DNA-binding factor; CRY; cryptochrome; EMT; epithelial-mesenchymal transition; FGD; fa

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2018 سفارش ترجمه

STAT3: The art of multi-tasking of metabolic and immune functions in obesity

Keywords: Signal transducer and activator of transcription 3; Obesity; Metabolism; Lipid; Immune; AgRP; Agouti-related peptide; AMPK; AMP-activated protein kinase; AOX; acyl-CoA oxidase; ARC; arcuate nucleus; ATGL; adipose triglyceride lipase; BAT; brown adipose ti

دانلود رایگان متن کامل مقاله ISI 51 صفحه سال انتشار : 2018 سفارش ترجمه

Therapeutic implication of vascular endothelial growth factor receptor-1 (VEGFR-1) targeting in cancer cells and tumor microenvironment by competitive and non-competitive inhibitors

Keywords: ADCC; antibody dependent cell-mediated cytotoxic activity; ALL; acute lymphoid leukemia; AML; acute myeloid leukemia; CXCL; C-X-C motif chemokine ligand; ECM; extra-cellular matrix; EGFR; epidermal growth factor receptor; ERK; extracellular signal-regulat

دانلود رایگان متن کامل مقاله ISI 51 صفحه سال انتشار : 2018 سفارش ترجمه

Recent advances of RAF (rapidly accelerated fibrosarcoma) inhibitors as anti-cancer agents

Keywords: MAPK; RAF inhibitors; Anti-cancer agents; Abl; Abelson murine leukemia viral oncogene; ATP; Adenine triphosphate; Bcl-2; B-cell lymphoma; CNS; Central nervous system; COX-2; Cyclo-oxygenase enzyme-2; CR; Conserved region; CRD; Cysteine-rich domain; DFG; A

دانلود رایگان متن کامل مقاله ISI 57 صفحه سال انتشار : 2018 سفارش ترجمه

Nanomedicines and gene therapy for the delivery of growth factors to improve perfusion and oxygenation in wound healing

Keywords: Ang-1; angiopoietin 1; AP-57; antimicrobial peptide 57; CS; chitosan; Cur; curcumin; ECM; extracellular matrix; EGF; epidermal growth factor; eNOS; endothelial nitric oxide synthase; EPCs; endothelial progenitor cells; EPR; electron paramagnetic resonance

دانلود رایگان متن کامل مقاله ISI 67 صفحه سال انتشار : 2018 سفارش ترجمه

ERK1/2 inhibitors: New weapons to inhibit the RAS-regulated RAF-MEK1/2-ERK1/2 pathway

Keywords: Akt; oncogene in the transforming retrovirus, AKT8; AP-1; activator protein 1; ARAF; v-raf murine sarcoma 3611 viral oncogene homologue; ASK1; apoptosis signal-regulating kinase 1; BCL2; B-cell lymphoma 2; BCL-XL; B-cell lymphoma extra large; BRAF; v-raf

دانلود رایگان متن کامل مقاله ISI 68 صفحه سال انتشار : 2018 سفارش ترجمه

Potential effect on molecular pathways in different targeted genes in the VEGF family in retina - From the genomic point of view

Keywords: Expression; Gene network; Expression quantitative trait loci; Recombinant inbred; Vascular endothelial growth factor; AMD; age-related macular degeneration; BXD; C57BL/6J X DBA/2J; CNV; choroidal neovascularization; DME; diabetic macular edema; DR; diabet

دانلود رایگان متن کامل مقاله ISI 70 صفحه سال انتشار : 2018 سفارش ترجمه

Role of RET protein-tyrosine kinase inhibitors in the treatment RET-driven thyroid and lung cancers

Keywords: ARTN; artemin; AS; activation segment; CD; cadherin-like domain; CDK; cyclin-dependent protein kinase; CL; catalytic loop; CS or C-spine; catalytic spine; CTT; carboxyterminal tail; EGFR; epidermal growth factor receptor; FGFR; fibroblast growth factor re

دانلود رایگان متن کامل مقاله ISI 70 صفحه سال انتشار : 2018 سفارش ترجمه

A three-time-point method for assessing kinetic parameters of 64Cu-labeled Ramucirumab trapping in VEGFR-2 positive lung tumors

Keywords: Kinetic model; 64Cu-labeled PET tracer; VEGFR; Irreversible/reversible trapping;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2017 سفارش ترجمه

Hypoxia and HIF pathway in cancer and the placenta

Keywords: Oxygen; Hypoxia-inducible factor; Placenta; Trophoblast; Cancer; CCRCC; clear cell renal cell carcinoma; FasL; Fas ligand; FIH; factor inhibiting HIF; FLT1; fms-related tyrosine kinase 1; HIF; hypoxia-inducible factor; HLA; human leukocyte antigen; MHC; m

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Strong radioprotective FGF1 signaling down-regulates proliferative and metastatic capabilities of the angiosarcoma cell line, ISOS-1, through the dual inhibition of EGFR and VEGFR pathways

Keywords: Angiosarcoma; EGFR; FGF1; Metastasis; Radioprotector; VEGFR;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Original ResearchApatinib enhances antitumour activity of EGFR-TKIs in non-small cell lung cancer with EGFR-TKI resistance

Keywords: NSCLC; Apatinib; Gefitinib; EGFR; VEGFR;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Evaluation of the Response of Intracranial Xenografts to VEGF Signaling Inhibition Using Multiparametric MRI

Keywords: ADC; Apparent diffusion coefficient; DCE-MRI; Dynamic contrast-enhanced magnetic resonance imaging; DW-MRI; Diffusion-weighted magnetic resonance imaging; fBV; Fractional blood volume; H&E; Hematoxylin and eosin; IAUGC60; Initial area under the gadolinium

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Nilotinib Enhances Tumor Angiogenesis and Counteracts VEGFR2 Blockade in an Orthotopic Breast Cancer Xenograft Model with Desmoplastic Response

Keywords: VEGF; vascular endothelial growth factor; VEGFR; vascular endothelial growth factor receptor; α-SMA; α-smooth muscle actin; PDGF; platelet-derived growth factor; PDGFR; platelet-derived growth factor receptor; TPLSM; two-photon laser scanning microscopy

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Davallia bilabiata exhibits anti-angiogenic effect with modified MMP-2/TIMP-2 secretion and inhibited VEGF ligand/receptors expression in vascular endothelial cells

Keywords: D. bilabiata; Davallia bilabiata; MMPs; matrix metalloproteinases; VEGF; vascular endothelial growth factor; VEGFR; vascular endothelial growth factor receptor; CAM; chorioallantoic membrane; TIMP; tissue inhibitor of metalloproteinase; RECK; reversion-in

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Purinergic P2Y receptors: Molecular diversity and implications for treatment of cardiovascular diseases

Keywords: ADP; adenosine 5′-diphosphate; AgRP; agouti-related peptide; AMPK; 5′-AMP-activated protein kinase; ApnA; diadenosine polyphosphate; ApoE; apolipoprotein E; AT1R; angiotensin II type 1 receptor; ATP; adenosine 5′-triphosphate; BN-PAGE; blue native-p

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2017 سفارش ترجمه

Overcoming ABC transporter-mediated multidrug resistance: The dual role of tyrosine kinase inhibitors as multitargeting agents

Keywords: MDR; BCR-ABL inhibitors; EGFR inhibitors; VEGFR inhibitors; Drug combinations; ABC; ATP binding cassette; ADME-tox; absorption, distribution, metabolism, excretion, toxicity; AKT; v-akt murine thymoma viral oncogene homolog; ALL; acute lymphoblastic leuke

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2017 سفارش ترجمه

Anti-angiogenic potential of trypsin inhibitor purified from Cucumis melo seeds: Homology modeling and molecular docking perspective

Keywords: BSA; bovine serum albumin; DMEM; Dulbecco's modified eagle's medium; BBI; Bowman-Birk inhibitor; ELISA; enzyme-linked immunosorbent assay; FBS; fetal bovine serum; HUVEC; human umbilical vein endothelial cells; LDH; lactate dehydrogenase; MTT; 3-(4,5-

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2017 سفارش ترجمه

Risk of Distinctive Hair Changes Associated With Pazopanib in Patients With Renal Cell Carcinoma (RCC) Versus Patients Without RCC: A Comparative Systematic Review and Meta-analysis

Keywords: Alopecia; Color; Kidney; Tumor; VEGFR;

دانلود رایگان متن کامل مقاله ISI 48 صفحه سال انتشار : 2017 سفارش ترجمه

Anaplastic lymphoma kinase (ALK) inhibitors in the treatment of ALK-driven lung cancers

Keywords: Alectinib: (PubMED CID: 49806720); Brigatinib: (PubMED CID: 68165256); Ceritinib: (PubMED CID: 57379345); Crizotinib (PubMED CID: 11626560); Entrectinib: (PubMED CID: 25141092); Lorlatinib: (PubMed CID: 71731823); ALK+-NSCLC; ALK-positive non-small cell l

دانلود رایگان متن کامل مقاله ISI 60 صفحه سال انتشار : 2017 سفارش ترجمه

A phase II study of nintedanib in patients with relapsed small cell lung cancer

Keywords: Nintedanib; SCLC; VEGFR;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

Discovery of novel dual inhibitors of VEGFR and PI3K kinases containing 2-ureidothiazole scaffold

Keywords: 2-Aminothiazole; VEGFR; PI3K; Anticancer

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Inhibition of VEGF-dependent angiogenesis by the anti-CD82 monoclonal antibody 4F9 through regulation of lipid raft microdomains

Keywords: CD82; 4F9; VEGF; VGFR2; Angiogenesis; BSA; bovine serum albumin; EC; endothelial cell; HUVEC; human umbilical vein endothelial cell; IL-6; interleukin-6; IL-6R; interleukin-6 receptor; mAb; monoclonal antibody; RTK; receptor tyrosine kinase; shCD82; shRNA

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Alpha-fetoprotein is a biomarker of unfolded protein response and altered proteostasis in hepatocellular carcinoma cells exposed to sorafenib

Keywords: AFP; alpha-feto protein; AREG; amphiregulin; ATF6; activating transcription factor-6; DFX; deferoxamine; eIF-2α; eukaryotic translation initiation factor-2α; ERK1/2; extracellular signal-regulated kinase 1/2; IRE-1α; inositol-requiring enzyme-1α; GRP;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Labeling and preliminary in vivo assessment of niobium-labeled radioactive species: A proof-of-concept study

Keywords: 95/90Nb; Bevacizumab; Labeling; VEGFR; Biodistribution; PET imaging;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Limited versus total epithelial debridement ocular surface injury: Live fluorescence imaging of hemangiogenesis and lymphangiogenesis in Prox1-GFP/Flk1::Myr-mCherry mice

Keywords: NV; neovascularization; HA; hemangiogenesis; LA; lymphangiogenesis; Flk; fetal liver kinase; GFP; green fluorescent protein; Prox-1; Prospero Homeobox 1; VEGF; vascular endothelial growth factor; VEGFR; vascular endothelial growth factor receptor; Cornea;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Synergistic inhibition of sunitinib and ethaselen against human colorectal cancer cells proliferation

Keywords: TKI; tyrosine kinase inhibitor; VEGFRs; vascular endothelial growth factor receptors; PDGFRs; platelet-derived growth factor receptors; NSCLC; non-small cell lung cancer; Trx; thioredoxin; TrxR; thioredoxin reductase; BBSKE; ethaselen; ROS; reactive oxyge

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Recent advances in the development of dual VEGFR and c-Met small molecule inhibitors as anticancer drugs

Keywords: VEGFR; c-Met; Dual inhibitor; Anti-cancer drugs

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Original ArticleWound HealingDelayed Healing of Sickle Cell Ulcers Is due to Impaired Angiogenesis and CXCL12 Secretion in Skin Wounds

Keywords: EPC; endothelial progenitor cell; PBS; phosphate buffered saline; SCD; sickle cell disease; VEGF; vascular endothelial growth factor; VEGFR; vascular endothelial growth factor receptor; WT; wild type;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Two anti-angiogenic TKI-PET tracers, [11C]axitinib and [11C]nintedanib: Radiosynthesis, in vivo metabolism and initial biodistribution studies in rodents

Keywords: Axitinib; Nintedanib; TKI-Pet; Personalized medicine; VEGFR

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

ReviewTargeting VEGF in eye neovascularization: What's new?: A comprehensive review on current therapies and oligonucleotide-based interventions under development

Keywords: AMD; age-related macular degeneration; DR; diabetic retinopathy; EC; endothelial cell; VEGF; vascular endothelial growth factor; PLGF; placental growth factor; DME; diabetic macular edema; RVO; retinal vein occlusion; PRN; pro re nata; VEGFR; VEGF recepto

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2016 سفارش ترجمه

PLGA-based nanoparticles: A new paradigm in biomedical applications

Keywords: Biodegradable; Poly(lactic-co-glycolic acid); Nanoparticles; Targeting; Sustained release; DCC; N,N-Dicyclohexylcarbodiimide; DDS; Drug delivery system; DNA; Deoxyribose nucleic acid; EDC; 1-ethyl-3-(3-dimethylaminopropyl carbodiimide); EGFR; Epidermal gr

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2016 سفارش ترجمه

Functional role of inorganic trace elements in angiogenesis part III: (Ti, Li, Ce, As, Hg, Va, Nb and Pb)

Keywords: As; arsenic; FGF-2; basic fibroblast growth factor; BMP-2; bone morphogenetic protein-2; Ce; cerium; COX; cyclooxygenase; EC; endothelial cells; EPCR; endothelial cell protein C receptor; EPCs; endothelial progenitor cells; EMT; epithelial to mesenchymal

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2016 سفارش ترجمه

Polycations and their biomedical applications

Keywords: Ac-aCD; acetalated cyclodextrin; ASC; adipose-derived stromal cell; αSMA; α-smooth muscle actin; BMA; butyl methacylate; BMP; bone morphogenetic protein; BSA; bovine serum albumin; CDP; cyclodextrin-containing polymer; CPLA; cationic polylactide; cRGD;

دانلود رایگان متن کامل مقاله ISI 78 صفحه سال انتشار : 2016 سفارش ترجمه

VEGFR2 predicts decreased patients survival in soft tissue sarcomas

Keywords: VEGFR; PDGFR; Sarcoma; Immunohistochemistry; Survival;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2015 سفارش ترجمه

Genetic profiling of advanced radioactive iodine-resistant differentiated thyroid cancer and correlation with axitinib efficacy

Keywords: Axitinib; Advanced differentiated thyroid cancer; BRAF; RAS; VEGFR; PIK3CA

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Endothelial progenitor cells induce transplant arteriosclerosis via VEGFR-1/2 activity

Keywords: Endothelial progenitor cells; Transplant arteriosclerosis; VEGFR-1/2; AR; acute rejection; Akt; protein kinase B; CAV; cardiac allograft vasculopathy; CD31; cluster of differentiation 31; CM-Dil; chlormethyl-benzamidodialkylcarbocyanine; DiI-ac-LDL; DiI-l

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه