A three-time-point method for assessing kinetic parameters of 64Cu-labeled Ramucirumab trapping in VEGFR-2 positive lung tumors

Three independent kinetic parameters (Ki, kR and F) can be assessed from three data points acquired at early, mid and late imaging, i.e., at 3, 24 and 48 h post-injection, for further characterization of 64Cu-NOTA-RamAb trapping in VEGFR-2 positive lung tumors.