دانلود مقالات ISI درباره Vla-4 + ترجمه فارسی

اثر گلیسولین پلاسما بر بلوغ انسانی اریتروبلاست برای تولید اریتروسیت

The effects of plasma gelsolin on human erythroblast maturation for erythrocyte production

Keywords: GSN; gelsolin; pGSN; human recombinant plasma gelsolin; cGSN; cytoplasmic gelsolin; HSCs; hematopoietic stem cells; GATA-1; GATA-binding factor 1; VLA-4; very late antigen-4; ICAM-4; intracellular adhesion molecule-4; DLC-1; deleted in liver cancer-1; Rho

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

سیناپس ایمونولوژیک به عنوان هدف دارویی

The immunological synapse as a pharmacological target

Keywords: AP-1; activating protein 1; APC; antigen presenting cell; CAR; chimeric antigen receptors; Cbl-b; casitas B-lineage lymphoma; DAG; diacylglycerol; cSMAC; central supramolecular activation cluster; CTLA4; cytotoxic T lymphocyte antigen 4; dSMAC; distal sup

دانلود رایگان متن کامل مقاله ISI 69 صفحه سال انتشار : 2018 سفارش ترجمه

پویایی مولکولی چسبندگی لکوکسیتی پس از دفع ناتالیزوماب در مولتیپل اسکلروزیس

Leukocyte adhesion molecule dynamics after Natalizumab withdrawal in Multiple Sclerosis

Keywords: Natalizumab withdrawal; VLA-4; Adhesion molecules; Dynamics; Multiple Sclerosis;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

نقش استروما تومور در مقاومت در برابر درمان ضد آنژیوژنیک

Role of the tumor stroma in resistance to anti-angiogenic therapy

Keywords: Ab; antibody; ACT; adoptive cell therapy; ANG; angiopoietin; ATP; adenosine triphosphate; BMDC; bone marrow derived cell; CA4P; combretastatin A phosphate; CAF; cancer-associated fibroblast; CCL2; C-C motif ligand 2; CD; cluster differentiation antigen; C

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

بررسی مقالات اهداف تهاجمی درمانی در بیماری سلول داسی شکل

Review ArticleInflammatory targets of therapy in sickle cell disease

Keywords: ICAM-1; intercellular adhesion molecule 1; LFA-1; leukocyte function-associated antigen 1; PECAM; platelet endothelial cell adhesion molecule; VCAM-1; vascular cell adhesion molecule 1; VLA-4; very late antigen-4;

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2016 سفارش ترجمه

سرم از بیماران آپنه انسدادی باعث پاسخگویی التهابی در سلولهای اندوتلیال عروق کرونر می شود

Serum from obstructive sleep apnea patients induces inflammatory responses in coronary artery endothelial cells

Keywords: Obstructive sleep apnea; Inflammation; Hypoxia; Serum; Bioassay; AHI; apnea-hypopnea index; BMI; body mass index; CCL5; chemokine ligand 5; CPAP; continuous positive air pressure; CRP; C-reactive protein; CVD; cardiovascular disease; CXCL12; stromal cell-

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2016 سفارش ترجمه

مدولاسیون ایمنی میزبان توسط بزاق تیک

Modulation of host immunity by tick saliva

Keywords: Akt; protein kinase B; BMDMs; bone marrow-derived macrophages; BSA; bovine serum albumin; cAMP; cyclic adenosine monophosphate; CCL; chemokine (C-C motif) ligand; CCR; C-C motif receptor; CD; cluster of differentiation; ConA; concanavalin A; CTL; cyto

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

لاکوینیمود اثرات بالینی و ایمنی مفصل را در موش های صحرایی نوریس خودکار ایمنی آزمایش موش صحرایی لوییس اثبات می کند

Laquinimod exerts strong clinical and immunomodulatory effects in Lewis rat experimental autoimmune neuritis

Keywords: GBS; Guillain-Barre syndrome; CIDP; chronic inflammatory demyelinating polyneuropathy; AIDP; acute inflammatory demyelinating polyneuropathy; EAN; experimental autoimmune neuritis; EAE; experimental autoimmune encephalomyelitis; PNS; peripheral nervous

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

نقش آسیب شناسی اکسید نیتریک گلیال در بیماری های التهابی عصبی بزرگسالان و کودکان

Pathologic role of glial nitric oxide in adult and pediatric neuroinflammatory diseases

Keywords: AD; Alzheimer's disease; ALD; X-linked adrenoleukodystrophy; ALDRP; adrenoleukodystrophy-related protein; ALDP; adrenoleukodystrophy protein; ALS; amyotrophic lateral sclerosis; ATF-2; activating transcription factor 2; BBB; blood-brain barrier; AP-1; a

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2014 سفارش ترجمه

گیرنده های سطحی سلول های نوتروفیل و مسیرهای انتقال سیگنال داخل سلولی آنها

Neutrophil cell surface receptors and their intracellular signal transduction pathways

Keywords: Abl; Abelson leukemia proto-oncogene; ADAP; adhesion and degranulation promoting adapter protein (Fyb, SLAP-130); Asc; apoptosis-associated speck-like protein containing a CARD; BCR; B-cell receptor; C3G; Crk SH3 domain-binding guanine nucleotide exchange

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Biomimetic nanoparticles for inflammation targeting

Keywords: apoE-/- mice; Apolipoprotein e knockout mice; CAM; cellular adhesion molecule; CCL5; chemokine (C-C motif) ligand 5; CD40L; cluster of differentiation 40 ligand; CTC; circulating tumor cell; CTL; cytotoxic T cell or CD8+ T cell; CXCL4; chemokine (C-X-

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

Preliminary evaluation of 18F-labeled LLP2A-trifluoroborate conjugates as VLA-4 (α4β1 integrin) specific radiotracers for PET imaging of melanoma

Keywords: 18F-trifluoroborates; VLA-4; α4β1 integrin; LLP2A peptidomimetic; Positron emission tomography; Melanoma;

دانلود رایگان متن کامل مقاله ISI 47 صفحه سال انتشار : 2018 سفارش ترجمه

T cell acute lymphoblastic leukemia (T-ALL): New insights into the cellular origins and infiltration mechanisms common and unique among hematologic malignancies

Keywords: Diapedesis; T-cells; Central nervous system; Endothelial transmigration; CXCR4; CXCL12; LFA-1; VLA-4; Selectin;

دانلود رایگان متن کامل مقاله ISI 57 صفحه سال انتشار : 2018 سفارش ترجمه

Nanomedicines for the treatment of hematological malignancies

Keywords: BMSC; Bone marrow stromal cell; BM; bone marrow; VCAM1; Vascular cell adhesion molecule 1; VLA-4; Very late antigen-4; HM; hematological malignancy; CLL; Chronic lymphocytic leukemia; ICAM1; Intercellular adhesion molecule 1; VEGF; Vascular endothelial gr

دانلود رایگان متن کامل مقاله ISI 85 صفحه سال انتشار : 2018 سفارش ترجمه

The role of T cells in the pathogenesis of Parkinson's disease

Keywords: AD; Alzheimer's disease; ALS; amyotrophic lateral sclerosis; APC; antigen-presenting cell; AQP4; Aquaporin-4; BBB; blood-brain barrier; BCL6; B cell lymphoma 6; BCR; B cell receptor; BEC; brain endothelial cells; CCL20; C-C motif ligand 20; CCR2; C-C

دانلود رایگان متن کامل مقاله ISI 87 صفحه سال انتشار : 2018 سفارش ترجمه

In vitro VLA-4 blockade results in an impaired NK cell-mediated immune surveillance against melanoma

Keywords: MS; multiple sclerosis; NTZ; natalizumab; VLA-4; very late antigen-4; VCAM-1; vascular cell adhesion protein-1; aNK cells; polyclonal activated NK cells; fNK cells; freshly isolated NK cells; NK cells; Melanoma; Natalizumab; Multiple sclerosis; VLA-4;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Microenvironment interactions and B-cell receptor signaling in Chronic Lymphocytic Leukemia: Implications for disease pathogenesis and treatment

Keywords: APRIL; a proliferation-inducing ligand; ATM; ataxia telangiectasia mutated; BAFF; B-cell activating factor; BAFFR; BAFF receptor; BAG6; BCL2-associated athanogene 6; BCMA; B-cell maturation antigen; BCL2; B-cell lymphoma 2; BCR; B cell receptor; bFGF; bas

دانلود رایگان متن کامل مقاله ISI 49 صفحه سال انتشار : 2016 سفارش ترجمه

Respiratory infection with a bacterial pathogen attenuates CNS autoimmunity through IL-10 induction

Keywords: Experimental autoimmune encephalomyelitis; Multiple sclerosis; CNS inflammation; Infection; Bordetella pertussis; IL-10; Th17 cell; Th1 cell; VLA-4; LFA-1; Immune regulation; Hygiene hypothesis;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Staphylococcal enterotoxin A regulates bone marrow granulocyte trafficking during pulmonary inflammatory disease in mice

Keywords: VCAM-1; ICAM-1; VLA-4; MAC-1; Cell trafficking; SDF-1α;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

High CXCR4 and low VLA-4 expression predicts poor survival in adults with acute lymphoblastic leukemia

Keywords: VLA-4; CXCR4; Acute lymphoblastic leukemia; Adult; Survival; Prognostic marker;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Investigation of the teratogenic potential of VLA-4 antagonist derivatives in rats

Keywords: Developmental toxicity; Ventricular septal defect; VLA-4; Rats;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

The PDZ-binding domain of syndecan-2 inhibits LFA-1 high-affinity conformation

Keywords: EGTA; ethylene glycol tetraacetic acid; HUVEC; human umbilical vein endothelial cell; ICAM-1; intercellular adhesion molecule 1; LFA-1; lymphocyte function-associated antigen 1; pLys; poly-d-lysine; PMA; phorbol-12-myristate-13-acetate; PtdIns[4,5]P2; pho

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Synthesis and evaluation of 4,5-dihydro-5-methylisoxazolin-5-carboxamide derivatives as VLA-4 antagonists

Keywords: VLA-4; Proline; Isoxazoline; Antagonist;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2013 سفارش ترجمه

Arylsulfonamide pyrimidines as VLA-4 antagonists

Keywords: α4β1; VLA-4; Antagonist; Orally available; CIA model; EAE model;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Brownian nanoimaging of interface dynamics and ligand-receptor binding at cell surfaces in 3-D

Keywords: VLA-4; very late antigen-4; CD49d/CD29; α4β1-integrin; FN296; a recombinant construct of fibronectin type III repeats [domains 8-10 plus domains 12-14 including the alternatively-spliced CS-1 domain] available commercially as RetroNectin (Takara Bio USA

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Elevated markers of inflammation and endothelial activation and increased counts of intermediate monocytes in adult survivors of childhood acute lymphoblastic leukemia

Keywords: ALL; acute lymphoblastic leukemia; CKD-EPI; Chronic Kidney Disease Epidemiology Collaboration; CV; cardiovascular; eGFR; estimated glomerular filtration rate; HDL; high-density lipoproteins; hsCRP; high-sensitivity C-reactive protein; IL; interleukin; LDL

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Comparison of two cross-bridged macrocyclic chelators for the evaluation of 64Cu-labeled-LLP2A, a peptidomimetic ligand targeting VLA-4-positive tumors

Keywords: Copper-64; VLA-4; PET imaging

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

A novel, potent, and orally active VLA-4 antagonist with good aqueous solubility: trans-4-[1-[[2-(5-Fluoro-2-methylphenylamino)-7-fluoro-6-benzoxazolyl]acetyl]-(5S)-[methoxy(methyl)amino]methyl-(2S)-pyrrolidinylmethoxy]cyclohexanecarboxylic acid

Keywords: VLA-4; Eosinophil infiltration; Asthma; Aqueous solubility

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2013 سفارش ترجمه

Antibody to α4 integrin suppresses natural killer cells infiltration in central nervous system in experimental autoimmune encephalomyelitis

Keywords: Natalizumab; VLA-4; Multiple sclerosis; EAE; PML; Flow cytometry;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Tyrosine modified analogues of the α4β7 integrin inhibitor biotin-R8ERY prepared via Click Chemistry: Synthesis and biological evaluation

Keywords: CuAAC; copper catalyzed azide-alkyne cycloaddition; FAK; focal adhesion kinase; FBS; fetal bovine serum; GALT; gut-associated lymphoid tissues; GnHCl; guanidine hydrochloride; GVHD; graft-versus-host disease; HBSS; Hank's buffered salt solution; HMP; 4-

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Tumor necrosis factor-α enhanced fusions between oral squamous cell carcinoma cells and endothelial cells via VCAM-1/VLA-4 pathway

Keywords: Oral squamous carcinoma; VCAM-1; VLA-4; Cell fusion; Tumor necrosis factor-α

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Monocytic adhesion molecule expression and monocyte–endothelial cell dysfunction are increased in patients with peripheral vascular disease versus patients with abdominal aortic aneurysms

Keywords: Monocyte adhesion molecules; Integrins; CD18; CD11a; CD11b; CD11c; VLA-4; Monocyte isolation; Endothelial barrier dysfunction; Peripheral vascular disease

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Identification of trans-4-[1-[[7-fluoro-2-(1-methyl-3-indolyl)-6-benzoxazolyl]acetyl]-(4S)-fluoro-(2S)-pyrrolidinylmethoxy]cyclohexanecarboxylic acid as a potent, orally active VLA-4 antagonist

Keywords: VLA-4; Integrin; Eosinophil infiltration; Asthma

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Immune response modifiers in the treatment of asthma: A PRACTALL document of the American Academy of Allergy, Asthma & Immunology and the European Academy of Allergy and Clinical Immunology

Keywords: Immune response modifiers; monoclonal antibodies; asthma; allergic diseases; APC; Antigen-presenting cell; CRTH2; Chemoattractant receptor-homologous molecule expressed on TH2 cells (also known as DP2); FDA; US Food and Drug Administration; Feno; Fraction

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2012 سفارش ترجمه

Natalizumab therapy decreases surface expression of both VLA-heterodimer subunits on peripheral blood mononuclear cells

Keywords: Natalizumab; Multiple sclerosis; VLA-4; Beta-1 integrin; Adhesion molecule; Blood-brain-barrier; Flow cytometry;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Regulation of acute graft-versus-host disease by human umbilical cord blood derived stromal cells in haploidentical stem cell transplantation in mice through very late activation antigen-4

Keywords: hUCBDSCs; Human umbilical cord blood derived stromal cells; VLA-4; Very late activation antigen-4; GVHD; Graft-versus-host disease; hBMSCs; Human bone marrow stromal cells; HSCT; Hematopoietic stem cell transplantation; MNCs; Mononuclear cells; Very late

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Role of the Mac-1 and VLA-4 integrins, and concomitant Th2-cytokine production, in nitric oxide modulated eosinophil migration from bone marrow to lungs in allergic mice

Keywords: BAL; bronchoalveolar lavage; iNOS; inducible nitric oxide synthase; ICAM-1; intercellular adhesion molecule-1; LFA-1; leukocyte function-associated molecule-1; Mac-1; membrane-activated complex-1; 1400W; N-3-aminomethyl-benzyl-acetamidine; NO; nitric oxid

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Disruption of central nervous system barriers in multiple sclerosis

Keywords: BBB; BCB; MS; EAE; CAMs; Transmigration; Neuroinflammation; Choroid plexus; Basal lamina; Basement membrane; Endothelial cells; Tight junctions; Adherens junctions; Astrocyte; Chemokine; ECM; Pericyte; ICAM-1; VCAM-1; ALCAM; VLA-4; P-selectin; Ependyma

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2011 سفارش ترجمه

Asthma translational medicine: Report card

Keywords: ACQ; asthma control questionnaire; AHR; airway hyper-responsiveness; AP-1; activator protein 1; APC; antigen-presenting cell; AQLQ; asthma quality-of-life questionnaire; BALF; bronchoalveolar lavage fluid; CTLA-4; cytotoxic T lymphocyte-associated antigen

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2011 سفارش ترجمه

Role of CRTAM during mouse early T lymphocytes development

Keywords: CRTAM; class-I MHC-restricted T cell-associated molecule; PDZ; common structural domain present in PSD-95, Dlg, and ZO-1 proteins; VCAM; vascular cell adhesion molecule; LFA3; lymphocyte function-associated antigen-3; LFA1; lymphocyte function-associated

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Laquinimod interferes with migratory capacity of T cells and reduces IL-17 levels, inflammatory demyelination and acute axonal damage in mice with experimental autoimmune encephalomyelitis

Keywords: Laquinimod; Acute axonal damage; Cytokines; EAE; Pathology; VLA-4;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2010 سفارش ترجمه

Discovery of N-{N-[(3-cyanobenzene) sulfonyl]-4(R)-(3,3-difluoropiperidin-1-yl)-(l)-prolyl}-4-[(3′,5′-dichloro-isonicotinoyl) amino]-(l)-phenylalanine (MK-0617), a highly potent and orally active VLA-4 antagonist

Keywords: VLA-4; Antagonist; Multiple scelerosis

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2009 سفارش ترجمه

Macrophage inflammatory protein-1β induced cell adhesion with increased intracellular reactive oxygen species

Keywords: AngII; angiotensin II; CAMs; cell adhesion molecules; CVD; cardiovascular disease; DCFHDA; 2′7′-dichlorofluorescein-diacetate; DPI; diphenyleneiodonium; ECs; endothelial cells; FBS; fetal bovine serum; GTP; guanosine triphosphate; HIV; human immunodef

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

A novel and potent VLA-4 antagonist based on trans-4-substituted cyclohexanecarboxylic acid

Keywords: VLA-4; Integrin; trans-4-Substituted cyclohexanecarboxylic acid; Pharmacophore

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2009 سفارش ترجمه

Blocking α4-integrins - A small molecule approach to treatment of multiple sclerosis

Keywords: Multiple sclerosis; VLA-4; Alpha4; VCAM-1; Natalizumab; Tysabri®;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2008 سفارش ترجمه

Constraining the amide bond in N-Sulfonylated dipeptide VLA-4 antagonists

Keywords: VLA-4; Peptide bond mimetic; Bicyclic VLA-4 antagonists; Imidazole VLA-4 antagonists

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2008 سفارش ترجمه

Imidazopyridines as VLA-4 integrin antagonists

Keywords: VLA-4; Integrin; Imidazopyridine; Phenylalanine

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2008 سفارش ترجمه

HMG-CoA reductase inhibitors deplete circulating classical and non-classical monocytes following human heart transplantation

Keywords: Monocyte; Statin; Heart transplantation; Immunomodulation; VLA-4; FcγRI

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

Identification of 4-[1-[3-chloro-4-[N’-(5-fluoro-2-methylphenyl)ureido]phenylacetyl]-(4S)-fluoro-(2S)-pyrrolidinylmethoxy]benzoic acid as a potent, orally active VLA-4 antagonist

Keywords: VLA-4; Integrin; Oral availability

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

2,6-Quinolinyl derivatives as potent VLA-4 antagonists

Keywords: VLA-4; Quinoline; Inflammation;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2007 سفارش ترجمه