Keywords: پچ-کلمپ کل سلول; Caffeic acid phenethyl ester (CAPE); Myocardial contractility; Action potential; Calcium transient; Whole-cell patch-clamp; Ionic currents;
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The endogenous agonist, β-alanine, activates glycine receptors in rat spinal dorsal neurons
Keywords: پچ-کلمپ کل سلول; β-alanine; Spinal dorsal horn; Glycine receptors; GABAA receptors; Whole-cell patch-clamp; Chloride current;
Mechanism of sodium hydrosulfide modulation of L-type calcium channels in rat colonic smooth muscle cells
Keywords: پچ-کلمپ کل سلول; sodium hydrosulfide (PubChem CID: 28015); DL-dithiothreitol (PubChem CID: 446094); diamide (PubChem CID: 5353800); reduced L-glutathione (PubChem CID: 124886); L-type calcium channels; Whole-cell patch-clamp; Colon; Smooth muscle cells;
Acute Stress Persistently Alters Locus Coeruleus Function and Anxiety-like Behavior in Adolescent Rats
Keywords: پچ-کلمپ کل سلول; CNS; central nervous system; CRF; corticotropin-releasing factor; EPM; elevated plus maze; fMRI; Functional magnetic resonance imaging; LC; locus coeruleus; MAOIs; monoamine oxidase inhibitors; NE; norepinephrine; OFT; open-field test; PBS; phosphate-buff
STAT5 signaling in kisspeptin cells regulates the timing of puberty
Keywords: پچ-کلمپ کل سلول; Prolactin; Kiss1; Sexual maturation; HPG axis; Hypothalamus; Whole-cell patch-clamp; 3V; third ventricle; APs; Action potentials; AP-5; 2-amino-5-phophonovalerate; ARH; arcuate nucleus of the hypothalamus; AVPV; anteroventral periventricular nucleus of th
Contribution of presynaptic HCN channels to excitatory inputs of spinal substantia gelatinosa neurons
Keywords: پچ-کلمپ کل سلول; DRG; dorsal root ganglia; FSK; forskolin; GAD67; glutamic acid decarboxylase-67; GFP; green fluorescent protein; HCN channels; hyperpolarization-activated cyclic nucleotide-gated channels; Ih; h-current; IC50; half-maximal inhibitory concentration; IR; im
Synaptic scaling up in medium spiny neurons of aged BACHD mice: A slow-progression model of Huntington's disease
Keywords: پچ-کلمپ کل سلول; Medium spiny neuron; Whole-cell patch-clamp; Homeostatic scaling; Dendritic spine; Huntington's disease; AMPAR;
Voltage-gated calcium channels are abnormal in cultured spinal motoneurons in the G93A-SOD1 transgenic mouse model of ALS
Keywords: پچ-کلمپ کل سلول; ALS; amyotrophic lateral sclerosis; SOD1; superoxide dismutase-1; AMPA; α-amino-3-hydroxy-5-methylisoxazole propionic acid; VGCC; voltage-gated Ca2 + channel; PCCa; persistent Ca2 + current; mSOD1; mutant SOD1; TEA-Cl; tetraethylammonium chloride; 4-AP
Clostridium difficile toxin B inhibits the secretory response of human mast cell line-1 (HMC-1) cells stimulated with high free-Ca2+ and GTPγS
Keywords: پچ-کلمپ کل سلول; Human mast cell line-1 (HMC-1); Membrane capacitance; Whole-cell patch-clamp; GTPγS; Clostridium difficile toxin B (TcdB); Hexosaminidase;
Osmotic swelling activates a novel anionic current with VRAC-like properties in a cytoplasmic droplet membrane from Phycomyces blakesleeanus sporangiophores
Keywords: پچ-کلمپ کل سلول; Filamentous fungi; Whole-cell patch-clamp; Outward rectifier; Voltage-dependent inactivation; A-9-C
Presynaptic cell type-dependent regulation of GABAergic synaptic transmission by nitric oxide in rat insular cortex
Keywords: پچ-کلمپ کل سلول; ACSF; artificial cerebrospinal fluid; BSA; bovine serum albumin; cGMP; cyclic guanosine monophosphate; CTA; conditioned taste aversion; DAB; 3-3â²-diaminobenzidine; EGTA; ethylene glycol tetraacetic acid; FS; fast-spiking interneuron; GC; guanylyl cyclas
AHCYL2 (long-IRBIT) as a potential regulator of the electrogenic Na+-HCO3â cotransporter NBCe1-B
Keywords: پچ-کلمپ کل سلول; AD; DNA-activation domain; AHCYL; adenosylhomocysteine hydrolase-like protein; BD; DNA-binding domain; BPA; bovine parotid acinar; EGFP; enhanced green fluorescence protein; IB; immunoblot; IP; immunoprecipitation; IP3R; InsP3 receptor; IRBIT; InsP3 recep
Mechanism of osthole inhibition of vascular Cav1.2 current
Keywords: پچ-کلمپ کل سلول; Cav1.2 channel current; Osthole; Rat tail artery myocyte; Traditional eastern medicine; Whole-cell patch-clamp;
Effects of commonly used protein kinase inhibitors on vascular contraction and L-type Ca2+ current
Keywords: پچ-کلمپ کل سلول; Bay K 8644; (S)-(â)-methyl-1,4-dihydro-2,6-dimethyl-3-nitro-4-(2-trifluoromethylphenyl)pyridine-5-carboxylate; GF-109203X; 3-(N-[dimethylamino]propyl-3-indolyl)-4-(3-indolyl)maleimide; HA-1077; hexahydro-1-(5-isoquinolinylsulfonyl)-1H-1,4-diazepine; IBa
GluN2B-containing NMDA receptors as possible targets for the neuroprotective and antidepressant effects of fluoxetine
Keywords: پچ-کلمپ کل سلول; Neuroprotection; Depression; NMDA receptor subtypes; GluN2B subunit; Fluoxetine; Desipramine; Whole-cell patch-clamp
Presynaptic enhancement by eugenol of spontaneous excitatory transmission in rat spinal substantia gelatinosa neurons is mediated by transient receptor potential A1 channels
Keywords: پچ-کلمپ کل سلول; eugenol; excitatory transmission; spinal dorsal horn; TRPA1; whole-cell patch-clamp; painAITC, allyl isothiocyanate; AP, action potential; CNS, central nervous system; DRG, dorsal root ganglion; EC50, effective concentration producing half-maximal respons
Effects of pyrethroids on neuronal excitability of adult honeybees Apis mellifera
Keywords: پچ-کلمپ کل سلول; Pyrethroid; Honeybee; Whole-cell patch-clamp; Neuron; Sodium current
Effect of PGE2 on DA tone by EP4 modulating Kv channels with different oxygen tension between preterm and term
Keywords: پچ-کلمپ کل سلول; PDA; PGE2 receptor 4; Whole-Cell Patch-Clamp; Kv channel; Medicine;
Mechanism underlying the block of human Cav3.2 T-type Ca2+ channels by benidipine, a dihydropyridine Ca2+ channel blocker
Keywords: پچ-کلمپ کل سلول; Cav3.2; T-type Ca2+ channel; Benidipine; Ca2+ channel blocker; HEK-293 cells; Whole-cell patch-clamp; Ca2+ mobilization;
Acute ethanol exposure prevents PMA-mediated augmentation of N-methyl-d-aspartate receptor function in primary cultured cerebellar granule cells
Keywords: پچ-کلمپ کل سلول; N-methyl-d-aspartate receptor; Cerebellar granule cells; Protein kinase C; Whole-cell patch-clamp; Phorbol 12-myristate 13-acetate; Ethanol;
Electrophysiological characteristics of identified kidney-related neurons in adult rat spinal cord slices
Keywords: پچ-کلمپ کل سلول; Intermediolateral cell column; Preganglionic neuron; Pseudorabies virus; Sympathetic; Whole-cell patch-clamp;
Direct interaction and functional coupling between voltage-gated CaV1.3 Ca2+ channel and GABAB receptor subunit 2
Keywords: پچ-کلمپ کل سلول; L-Type Ca2+ channels; Baclofen; Whole-cell patch-clamp; Intracellular Ca2+
Action potential changes associated with impairment of functional properties of sodium channels in hippocampal neurons induced by melamine
Keywords: پچ-کلمپ کل سلول; Melamine; Hippocampus; Whole-cell patch-clamp; Voltage-gated sodium channels (VGSCs); Action potential
Nitrous oxide and the inhibitory synaptic transmission in rat dorsal horn neurons
Keywords: پچ-کلمپ کل سلول; Nitrous oxide; Analgesia; GABA; Glycine; Spinal cord slice; Dorsal horn; Whole-cell patch-clamp;
Phenformin has a direct inhibitory effect on the ATP-sensitive potassium channel
Keywords: پچ-کلمپ کل سلول; KATP channel; Phenformin; AMPK; Vascular smooth muscle cell; Whole-cell patch-clamp;
Cellular electrophysiological effects of changrolin in isolated rat cardiac myocytes
Keywords: پچ-کلمپ کل سلول; Changrolin; Whole-cell patch-clamp; Na+ channels; K+ channels; Ca2+ channels
Different oxidants and PKC isozymes mediate the opposite effect of inhibition of Qi and Qo site of mitochondrial complex III on calcium currents in rat cortical neurons
Keywords: پچ-کلمپ کل سلول; Cortical neurons; Mitochondrial complex III; Whole-cell patch-clamp; Calcium currents; Reactive oxygen species; Protein kinase C
Characteristics of ATP-activated current in nodose ganglion neurons of rats
Keywords: پچ-کلمپ کل سلول; Nodose ganglion neurons; ATP-activated currents; P2X receptor; Whole-cell patch-clamp
Brain-derived neurotrophic factor inhibits spontaneous inhibitory postsynaptic currents in the rat supraoptic nucleus
Keywords: پچ-کلمپ کل سلول; Brain-derived neurotrophic factor; GABA; Green fluorescent protein; Supraoptic nucleus; Whole-cell patch-clamp
Pain MechanismResearch PaperEffect of resiniferatoxin on glutamatergic spontaneous excitatory synaptic transmission in substantia gelatinosa neurons of the adult rat spinal cord
Keywords: پچ-کلمپ کل سلول; spinal dorsal horn; TRPV1; whole-cell patch-clamp; pain; AITC; allyl isothiocyanate; APV; dl-2-amino-5-phosphonovaleric acid; CNQX; 6-cyano-7-nitroquinoxaline-2,3-dione; DRG; dorsal root ganglion; EC50; effective concentration producing half-maximal respo
Quercetin antagonism of Bay K 8644 effects on rat tail artery L-type Ca2+ channels
Keywords: پچ-کلمپ کل سلول; Bay K 8644; Quercetin; Rat tail artery myocyte; Whole-cell patch-clamp
Nitrous oxide inhibits glutamatergic transmission in spinal dorsal horn neurons
Keywords: پچ-کلمپ کل سلول; Nitrous oxide; Analgesia; Glutamate receptors; Dorsal horn; Whole-cell patch-clamp;
Activity-dependent volume transmission by transgene NPY attenuates glutamate release and LTP in the subiculum
Keywords: پچ-کلمپ کل سلول; Neuropeptide Y; Gene therapy; Synaptic plasticity; Synaptic transmission; Activity-dependent release; Long-term potentiation (LTP); Whole-cell patch-clamp; Subiculum
Long-lasting enhancement in the intrinsic excitability of deep dorsal horn neurons
Keywords: پچ-کلمپ کل سلول; Intrinsic excitability; Pairing stimulation; Deep dorsal horn neuron; Whole-cell patch-clamp;
Morphological and physiological properties of serotonergic neurons in dissociated cultures from the postnatal rat dorsal raphe nucleus
Keywords: پچ-کلمپ کل سلول; Bombesin; Gastrin-releasing peptide; Phenylephrine; Postnatal rat dorsal raphe nucleus; Serotonergic neuron culture; Whole-cell patch-clamp; Serotonin immunocytochemistry; Inward rectifier K currents
Functional characterization of acid-sensing ion channels in cultured neurons of rat inferior colliculus
Keywords: پچ-کلمپ کل سلول; inferior colliculus; acid-sensing ion channel; whole-cell patch-clamp; cell cultureAP, action potential; APV, d-2-amino-5-phosphonopentanoic acid; ASIC, acid-sensing ion channel; [Ca2+]i, intracellular Ca2+ concentration; CNQX, 6-cyano-7-nitroquinoxaline-
Effects of static magnetic fields on the voltage-gated potassium channel currents in trigeminal root ganglion neurons
Keywords: پچ-کلمپ کل سلول; 125 mT; Static magnetic fields; Voltage-gated potassium channel; Trigeminal root ganglion neuron; Whole-cell patch-clamp
Oestrogen directly inhibits the cardiovascular L-type Ca2+ channel Cav1.2
Keywords: پچ-کلمپ کل سلول; Oestrogen; Hormones; L-type Ca2+ channel; Heterologous expression; Whole-cell patch-clamp;
Electrophysiological and immunofluorescence characterization of Ca2+ channels of acutely isolated rat sphenopalatine ganglion neurons
Keywords: پچ-کلمپ کل سلول; Sphenopalatine ganglion; Parasympathetic; N-type Ca2+ channels; Whole-cell patch-clamp; Immunofluorescence
Mechanisms of the antispasmodic activity of 3,5-di-t-butyl catechol (DTCAT) on rat vascular smooth muscles
Keywords: پچ-کلمپ کل سلول; Ca2+ channel blocker; 3,5-di-t-butyl catechol; Vascular smooth muscle; Whole-cell patch-clamp
Pharmacological and molecular characterization of ATP-sensitive K+ conductances in CART and NPY/AgRP expressing neurons of the hypothalamic arcuate nucleus
Keywords: پچ-کلمپ کل سلول; hypothalamic slice; whole-cell patch-clamp; energy balance; glucoseACSF, artificial cerebrospinal fluid; AgRP, agouti-related protein; ARC, hypothalamic arcuate nucleus; CART, cocaine-and-amphetamine-regulated transcript; DMSO, dimethyl sulfoxide; EGTA, e
Differences in kinetics of structurally related competitive GABAA receptor antagonists
Keywords: پچ-کلمپ کل سلول; GABAA receptor; Antagonist; Kinetics; Whole-cell patch-clamp;
Differentiating embryonic stem–derived neural stem cells show a maturation-dependent pattern of voltage-gated sodium current expression and graded action potentials
Keywords: پچ-کلمپ کل سلول; neural stem cells; sodium currents; neuronal differentiation; whole-cell patch-clamp; action potentials; TTXAHP, afterhyperpolarisation potential; EBSS, Earle’s balanced salt solution; EGTA, ethylene glycol-bis(2-aminoethylether)-tetraacetic acid; ES, emb
Amiloride attenuates glycine-induced currents in cultured neurons of rat inferior colliculus
Keywords: پچ-کلمپ کل سلول; Amiloride; Glycine receptor; Inferior colliculus; Whole-cell patch-clamp; Cell culture; Rat
The effects of paeonol on the electrophysiological properties of cardiac ventricular myocytes
Keywords: پچ-کلمپ کل سلول; Paeonol; Action potential; Sodium current; Ventricular myocyte; Whole-cell patch-clamp
Nicotinic ACh receptors in area postrema neurons of immature rat brain
Keywords: پچ-کلمپ کل سلول; Whole-cell patch-clamp; Area postrema neurons; ACh; Nicotinic ACh receptor; Muscarinic agonists; Atropine;
A role of insulin-like growth factor 1 in β amyloid-induced disinhibition of hippocampal neurons
Keywords: پچ-کلمپ کل سلول; Insulin-like growth factor 1; β Amyloid; Inhibitory postsynaptic current; Whole-cell patch-clamp; γ-Aminobutyric acid;
Inhibition of human TREK-1 channels by caffeine and theophylline
Keywords: پچ-کلمپ کل سلول; Caffeine; Theophylline; Seizures; TREK-1 channel; Whole-cell patch-clamp;
Potentiation, activation and blockade of GABAA receptors by etomidate in the rat sacral dorsal commissural neurons
Keywords: پچ-کلمپ کل سلول; general anesthetic; pelvic viscera; spinal cord; nystatin; whole-cell patch-clamp; BIC; bicuculline; DMSO; dimethyl sulfoxide; ECl; Clâ equilibrium potential; ET; etomidate; HEPES; N-2-hydroxyethylpiperazine-Nâ²-2-ethanesulphonic acid; IET; etomidate-a
FK962, a novel enhancer of somatostatin release, exerts cognitive-enhancing actions in rats
Keywords: پچ-کلمپ کل سلول; FK962; Memory; Passive avoidance; Somatostatin; Water maze; Whole-cell patch-clamp;