دانلود مقالات ISI درباره Xbp1 + ترجمه فارسی

Oxidative stress drives CD8+ T-cell skin trafficking in patients with vitiligo through CXCL16 upregulation by activating the unfolded protein response in keratinocytes

Keywords: Oxidative stress; unfolded protein response; CXCL16; CXCR6; CD8+ T cells; skin migration; DAPI; 4′-6-Diamidino-2-phenylindole; eIF2α; Eukaryotic initiation factor 2α; ER; Endoplasmic reticulum; HSPA5; Heat shock 70-kDa protein 5; IRE1α; Inositol-requ

دانلود رایگان متن کامل مقاله ISI 47 صفحه سال انتشار : 2017 سفارش ترجمه

Ethanol-induced damage to the developing spinal cord: The involvement of CCR2 signaling

Keywords: ATF6; Activating transcription factor 6; CCR2; Chemokine (C-C motif) receptor 2; CHOP; C/EBP Homologous Protein; CNS; Central nervous system; DNP; Dinitrophenol; eIF2α; Eukaryotic Initiation Factor 2α; ER; Endoplasmic reticulum; FASDs; Fetal alcohol s

دانلود رایگان متن کامل مقاله ISI 63 صفحه سال انتشار : 2017 سفارش ترجمه

Targeting chaperones, heat shock factor-1, and unfolded protein response: Promising therapeutic approaches for neurodegenerative disorders

Keywords: 17-AAG; 17-(allylamino)-17-demethoxygeldanamycin (tanespimycin); 17-DMAG; 17- dimethylaminoethylamino-17-demethoxygeldanamycin (alvespimycin); AAV; adeno-associated virus; Aβ; amyloid-β; AD; Alzheimer's disease; ALS; amyotrophic lateral sclerosis; APP;

دانلود رایگان متن کامل مقاله ISI 89 صفحه سال انتشار : 2017 سفارش ترجمه

Research paperUnfolded protein response in hypothalamic cultures of wild-type and ATF6α-knockout mice

Keywords: ER; endoplasmic reticulum; UPR; unfolded protein response; IRE1; inositol requiring enzyme 1; PERK; protein kinase RNA-like ER kinase; ATF6α; activating transcription factor 6α; XBP1; X-box binding protein 1; eIF2α; eukaryotic translation initiation fa

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

Dehydroascorbic acid-induced endoplasmic reticulum stress and leptin resistance in neuronal cells

Keywords: Dehydroascorbic acid (DHAA); Leptin; Unfolded protein response (UPR); Leptin resistance; Endoplasmic reticulum (ER) stress; DHAA; dehydroascorbic acid; AA; ascorbic acid; UPR; unfolded protein response; ATF6; activating transcription factor 6; CHOP; C/EBP

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

MiR-1271 upregulated by saturated fatty acid palmitate provokes impaired insulin signaling by repressing INSR and IRS-1 expression in HepG2 cells

Keywords: microRNA; miR-1271; Saturated fatty acid; Palmitate; Insulin resistance; INSR; IRS-1; Akt2; v-akt murine thymoma viral oncogene homolog 2; C/EBPα; CCAAT/enhancer binding protein alpha; ER; endoplasmic reticulum; FOXQ1; forkhead box Q1; GPC3; glypican 3;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

4-Phenylbutyric acid reduces mutant-TGFBIp levels and ER stress through activation of ERAD pathway in corneal fibroblasts of granular corneal dystrophy type 2

Keywords: ER stress; UPR; ERAD; 4-Phenylbutyric acid; TGFBIp; GCD2; Corneal fibroblasts; 4-PBA; Sodium 4-phenylbutyric acid; ATF6; Activating transcription factor 6; BiP; Binding immunoglobulin protein; CHOP; C/EBP homologous protein; ER; Endoplasmic reticulum; ERA

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Alpha-fetoprotein is a biomarker of unfolded protein response and altered proteostasis in hepatocellular carcinoma cells exposed to sorafenib

Keywords: AFP; alpha-feto protein; AREG; amphiregulin; ATF6; activating transcription factor-6; DFX; deferoxamine; eIF-2α; eukaryotic translation initiation factor-2α; ERK1/2; extracellular signal-regulated kinase 1/2; IRE-1α; inositol-requiring enzyme-1α; GRP;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Influence of the APOE genotype on hepatic stress response: Studies in APOE targeted replacement mice and human liver cells

Keywords: AD; Alzheimer's disease; APOE; apolipoprotein E; ATP; adenosine triphosphate; ATP5A1; ATP synthase subunit alpha, mitochondrial; B2M; beta-2 microglobulin; BAX; BCL2-associated X protein; BCL2; B-cell leukemia/lymphoma 2; BiP; binding immunoglobulin prote

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Original articleTauroursodeoxycholic acid improves pre-implantation development of porcine SCNT embryo by endoplasmic reticulum stress inhibition

Keywords: Porcine SCNT embryos; Endoplasmic reticulum stress; TUDCA; XBP1; Apoptosis;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Research paperPhosphatidylcholine as a metabolic cue for determining B cell fate and function

Keywords: CCTα; Antibody-secreting cell; Antibody; Germinal centers; T cell-dependent antigen; Unfolded protein response; Phospholipid biosynthesis; ASC; antibody-secreting cell; ER; endoplasmic reticulum; UPR; unfolded protein response; XBP1; X-box binding protei

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Palmitate-induced Endoplasmic Reticulum stress and subsequent C/EBPα Homologous Protein activation attenuates leptin and Insulin-like growth factor 1 expression in the brain

Keywords: 4-PBA; 4-phenyl butyric acid; 6-OHDA; 6-hydroxydopamine; Aβ; amyloid beta; AD; Alzheimer's disease; ATF3; activating transcription factor 3; ATF4; activating transcription factor 4; ATF6; activating transcription factor 6; BACE1; β-site APP cleaving enz

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2016 سفارش ترجمه

Alpha-lipoic acid attenuates endoplasmic reticulum stress-induced insulin resistance by improving mitochondrial function in HepG2 cells

Keywords: ALA; alpha-lipoic acid; ER stress; endoplasmic reticulum (ER) stress; HepG2; hepatoblastoma cell line; Tun; tunicamycin; OXPHOS; oxidative phosphorylation; Olig; oligomycin; T2DM; type 2 diabetes mellitus; IRS; insulin receptor substrate; PI3K; phosphatid

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2016 سفارش ترجمه

A highly sensitive assay of IRE1 activity using the small luciferase NanoLuc: Evaluation of ALS-related genetic and pathological factors

Keywords: ER stress; IRE1; XBP1; NanoLuc;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

A novel mutation in PNLIP causes pancreatic triglyceride lipase deficiency through protein misfolding

Keywords: BiP; immunoglobulin binding protein; ER; endoplasmic reticulum; GRP94; glucose-regulated protein-94; IRE1; inositol-requiring enzyme 1; PNLIP; pancreatic triglyceride lipase; PNLIPRP2; pancreatic lipase related protein 2; XBP1; X-box binding protein-1; Li

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

XBP1 induces snail expression to promote epithelial- to-mesenchymal transition and invasion of breast cancer cells

Keywords: XBP1; EMT; Breast cancer; Migration; Invasion;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Expression of citrate carrier gene is activated by ER stress effectors XBP1 and ATF6α, binding to an UPRE in its promoter

Keywords: Unfolded protein response; SLC25A1; ER protein acetylation; ATF6; XBP1; GRP78

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Cartilage-specific ablation of XBP1 signaling in mouse results in a chondrodysplasia characterized by reduced chondrocyte proliferation and delayed cartilage maturation and mineralization

Keywords: Chondrodysplasia; Endochondral ossification; ER stress; Growth plate; XBP1;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Calpain-1 induces endoplasmic reticulum stress in promoting cardiomyocyte apoptosis following hypoxia/reoxygenation

Keywords: ER; endoplasmic reticulum; H/R; hypoxia/re-oxygenation; I/R; ischemia/reperfusion; JNK1/2; c-Jun N-terminal protein kinase1/2; MI; myocardial infarction; MOI; multiplicity of infection; TAUR; tauroursodeoxycholate; CI-III; calpain inhibitor-III; CAST; cal

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Transcriptomics hit the target: Monitoring of ligand-activated and stress response pathways for chemical testing

Keywords: AD; adefovir dipivoxil; AhR; aryl hydrocarbon receptor; AMIO; amiodarone; APAP; acetaminophen; ATF4; activating transcription factor 4; CAA; chloroacetaldehyde; CdCl2; cadmium chloride; ChIP-seq; chromatin immunoprecipitation followed by DNA sequencing; C

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Disruption of the unfolded protein response (UPR) by lead compound selectively suppresses cancer cell growth

Keywords: Selective cancer therapy; Unfolded protein response; 2DG; UPR disrupter; UPR; unfolded protein response; 2DG; 2-deoxy-D-glucose; IRE1; inositol-requiring enzyme 1; XBP1; X-box binding protein 1; GRP78; glucose-regulated protein 78 kDa; TM; tunicamycin;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

A transgenic zebrafish model for monitoring xbp1 splicing and endoplasmic reticulum stress in vivo

Keywords: XBP1; Endoplasmic reticulum; ER stress; Transgenic zebrafish model

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

α-Synuclein-mediated inhibition of ATF6 processing into COPII vesicles disrupts UPR signaling in Parkinson's disease

Keywords: α-Synuclein; Unfolded protein response; ATF6; XBP1; Endoplasmic reticulum-associated degradation; COPII; Parkinson's disease; Neurodegeneration;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

MET Suppresses Epithelial VEGFR2 via Intracrine VEGF-induced Endoplasmic Reticulum-associated Degradation

Keywords: HGF; VEGF; ERAD; PI3 kinase; AKT; MEK; IRE1; XBP1

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2015 سفارش ترجمه

Hypoxic preconditioning and cell death from oxygen/glucose deprivation co-opt a subset of the unfolded protein response in hippocampal neurons

Keywords: EDTA; ethylenediaminetetraacetic acid; ER; endoplasmic reticulum; GF-EBSS; glucose-free Earle's Basic Salt Solution; HPC; hypoxic preconditioning; HSCs; hippocampal slice cultures; OGD; oxygen and glucose deprivation; PI; propidium iodide; RT; Reverse T

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2015 سفارش ترجمه

Role of Autophagy in the Maintenance of Intestinal Homeostasis

Keywords: IBD; Pathogenesis; Cell Biology; Genetics; AIEC; adherent invasive Escherichia coli; AMP; antimicrobial peptide; ATG; autophagy related; ATG16L1; autophagy-related 16 like 1; CD; Crohn's disease; ER; endoplasmic reticulum; IBD; inflammatory bowel diseas

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2015 سفارش ترجمه

Differential expression of X-box binding protein 1 during ovarian development and association between its SNP and growth-related parameters of the giant tiger shrimp Penaeus monodon

Keywords: Penaeus monodon; Xbp1; Gene expression; Ovarian development; Growth; SNP;

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2015 سفارش ترجمه

Hepatitis B virus X increases immune cell recruitment by induction of chemokine SDF-1

Keywords: ER stress; HBx; Immune cell recruitment; SDF-1; XBP1;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Cholesterol biosynthesis and ER stress in peroxisome deficiency

Keywords: Peroxisomes; Cholesterol; Isoprenoid; Pex2; SREBP-2; ER stress; Integrated stress response; Unfolded protein response; Zellweger syndrome; ACAT; acetoacetyl-CoA thiolase; ATF; activating transcription factor; BA; bile acid; CHOP; C/EBP homologous protein;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Positive contribution of IRE1α-XBP1 pathway to the expression of placental cathepsins

Keywords: IRE1α; XBP1; Cts7; Cts8;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Tick-borne encephalitis virus triggers inositol-requiring enzyme 1 (IRE1) and transcription factor 6 (ATF6) pathways of unfolded protein response

Keywords: Flavivirus; Tick-borne encephalitis virus; ER stress; XBP1; ATF6; Virus replication;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Target promiscuity and physicochemical properties contribute to pharmacologically induced ER-stress

Keywords: Endoplasmic reticulum stress; XBP1; ER-stress; in vivo toxicity; Physicochemical properties; Target promiscuity;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Chibby drives β catenin cytoplasmic accumulation leading to activation of the unfolded protein response in BCR-ABL1 + cells

Keywords: CML; chronic myeloid leukemia; TK; tyrosine kinase; LSC; leukemic stem cell; APC; Adenomatous polyposis coli; GSK3; glycogen synthase kinase 3; CBY; Chibby; TCF; T cell factor; LEF; lymphoid enhancer factor; ER; endoplasmic reticulum; UPR; unfolded protei

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

The hyperglycemia stimulated myocardial endoplasmic reticulum (ER) stress contributes to diabetic cardiomyopathy in the transgenic non-obese type 2 diabetic rats: A differential role of unfolded protein response (UPR) signaling proteins

Keywords: AMPK; 5′ adenosine monophosphate-activated protein kinase; ATF6; activated transcription factor 6; BW; body weight; CHOP/GADD153; CCAAT/-enhancer-binding protein homologous protein; CPT1; carnitine palmitoyl transferase 1; ER; endoplasmic reticulum; GLU

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Sorafenib enhances proteasome inhibitor-mediated cytotoxicity via inhibition of unfolded protein response and keratin phosphorylation

Keywords: Ab; antibody; ALLN; acetyl-leucyl-leucyl-norleucinal; ATF; activating transcription factor; CHOP; C/EBP homologous protein; DAPI; 4', 6-diamidino-2-phenylindole; eIF2; eukaryotic translation-initiation factor 2; ER; endoplasmic reticulum; GADD153; growth

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Bidirectional regulation of NF-κB by reactive oxygen species: A role of unfolded protein response

Keywords: NF-κB; nuclear factor-κB; UV; ultraviolet; IκB; inhibitor of NF-κB; IKK; IκB kinase; NEMO; NF-κB essential modulator; TNFR; tumor necrosis factor receptor; IL-1R; interleukin-1 receptor; NIK; NF-κB inducing kinase; LPS; lipopolysaccharide; PKD; pro

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Overexpression of human mutated G93A SOD1 changes dynamics of the ER mitochondria calcium cycle specifically in mouse embryonic motor neurons

Keywords: ALS; amyotrophic lateral sclerosis; AMPA; α-amino-5-methyl-3-hydroxyisoxazolone-4-propionat; CaBP; calcium binding proteins; CPA; cyclopiazonic acid; CsA; cyclosporine A; eIF2α; eukaryotic translation initiation factor 2 α; EMD; earth mover's distance;

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2013 سفارش ترجمه

THE ESSENTIAL BIOLOGY OF THE ENDOPLASMIC RETICULUM STRESS RESPONSE FOR STRUCTURAL AND COMPUTATIONAL BIOLOGISTS

Keywords: ER stress; unfolded protein response; ATF6; IRE1; PERK; XBP1; ERAD

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Protective effects of XBP1 against oxygen and glucose deprivation/reoxygenation injury in rat primary hippocampal neurons

Keywords: XBP1; OGD/reoxygenation; Neuroprotection; ER stress;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2012 سفارش ترجمه

Clinical Application of Basic ScienceStress management: How the unfolded protein response impacts fatty liver disease

Keywords: Unfolded protein response; Fatty liver disease; Adaptation; ER stress; Ern; Xbp1; BIP; Atf6; Eif2ak3;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Cage food location alters energy balance and endoplasmic reticulum stress in the brain of mice

Keywords: Unfolded protein response; Xbp1; Atf6; Voluntary exercise; Food location;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

AAV-mediated delivery of the transcription factor XBP1s into the striatum reduces mutant Huntingtin aggregation in a mouse model of Huntington’s disease

Keywords: Huntington’s disease; Unfolded protein response; Endoplasmic reticulum stress; XBP1; Htt aggregation; Gene therapy

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Redox signaling loops in the unfolded protein response

Keywords: AGR2; anterior gradient 2; ARE; antioxidant responsive element; ATF4; activating transcription factor-4; ATF6; activating transcription factor-6; ASK1; apoptosis signal-regulating kinase-1; BI-1; BAX inhibitor-1; BiP; immunoglobulin heavy chain-binding pr

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

The endoplasmic reticulum: a sensor of cellular stress that modulates immune responses

Keywords: ER-stress; IRE1; XBP1; TLR; Innate immunity;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

The endoplasmic reticulum stress response is involved in apoptosis induced by aloe-emodin in HK-2 cells

Keywords: AE; Aloe-emodin; ASK1; apoptosis signal-regulating kinase 1; ATF; activating transcription factor; CHAC1; cation transport regulator-like protein 1; CHOP; CAAT/enhancer-binding protein-homologous protein; DR5; death receptor 5; eIF2α; eukaryotic initiati

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Age-related cataracts: Homocysteine coupled endoplasmic reticulum stress and suppression of Nrf2-dependent antioxidant protection

Keywords: ARC; age-related cataract; ARE; antioxidant response element; ATF4; activating transcription factor 4; ATF6; activating transcription factor 6; Bip; ER-resident chaperone protein; CHOP; C/EBP homologous protein; DAPI; 4′,6-diamidino-2-phenylindole; DMEM

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Minimally modified low-density lipoprotein induces macrophage endoplasmic reticulum stress via toll-like receptor 4

Keywords: AS; atherosclerosis; LDL; low-density lipoprotein; mm-LDL; minimally modified LDL; ERS; endoplasmic reticulum stress; ox-LDL; oxidative modified LDL; GRP78; glucose-regulated proteins 78; IRE1; inositol-requiring enzyme 1; ATF6; activating transcription f

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Transcriptional deregulation of homeobox gene ZHX2 in Hodgkin lymphoma

Keywords: BHLHE40; EDEM1; H1C; Hodgkin lymphoma; Homeobox; MSX1; XBP1;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Function of yeast and amphioxus tRNA ligase in IRE1alpha-dependent XBP1 mRNA splicing

Keywords: ER stress; IRE1; RNA ligase; XBP1;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

The Cell Biology of the Unfolded Protein Response

Keywords: ER; endoplasmic reticulum; HRI; heme-regulated kinase; IFN; interferon; PKR; protein kinase; SREBP1c; sterol regulatory element-binding protein 1c; UPR; unfolded protein response; Xbp1; X-box binding protein 1;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه