Lanostane triterpenoids from Ganoderma luteomarginatum and their cytotoxicity against four human cancer cell lines

Nine undescribed lanostane triterpenoids were isolated from the fruiting bodies of Ganoderma luteomarginatum. (5α,24E)-3β-Acetoxyl-26-hydroxylanosta-8,24-dien-7-one (7) exhibited the highest cytotoxicity against HeLa and A549 cell lines, with IC50 values of 1.29 and 1.50 μM, respectively.232