کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10143893 | 1646226 | 2018 | 10 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Critical appraisal of oncological safety of stent as bridge to surgery in left-sided obstructing colon cancer; a systematic review and meta-analysis
ترجمه فارسی عنوان
ارزیابی انتقادی ایمنی انکولوژیک استنت به عنوان پل به جراحی در جلوگیری از چسبیدن به سرطان کولون؛ بررسی سیستماتیک و متا آنالیز
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
هماتولوژی
چکیده انگلیسی
This meta-analysis aims to determine the long-term oncological outcomes of SEMS as bridge to surgery (BTS) versus emergency surgery (ES). A systematic search without restrictions was conducted, and all studies comparing SEMS with ES reporting on long-term outcomes were included. Methodological quality was assessed using the appropriate tools. Twenty-one comparative studies were selected, reporting on 1919 patients. Meta-analysis showed no significant difference regarding three- and five-year overall survival (ORâ=â0·85 (0·68-1·08) and ORâ=â1·04 (0·68-1·57), respectively), disease-free survival (ORâ=â0·96 (0·73-1·26) and ORâ=â0·86 (0·54-1·36), respectively) and local recurrence rate (ORâ=â1·32 (0·78-2·23)). Permanent stomas were significantly lower in the SEMS group (OR 0·49 (0·32-0·74)). Sensitivity analysis on three-year survival showed opposite outcomes, with a trend towards worse survival in the SEMS group when only RCTs are taken into account. In conclusion, when in experienced hands, SEMS placement as BTS seems oncologically safe.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Critical Reviews in Oncology/Hematology - Volume 131, November 2018, Pages 66-75
Journal: Critical Reviews in Oncology/Hematology - Volume 131, November 2018, Pages 66-75
نویسندگان
Femke J. Amelung, Thijs A. Burghgraef, Pieter J. Tanis, Jeanin E. van Hooft, Frank ter Borg, Peter D. Siersema, Willem A. Bemelman, Esther C.J. Consten,