کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10160460 | 120 | 2005 | 10 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Biodegradable HA-PLA 3-D porous scaffolds: Effect of nano-sized filler content on scaffold properties
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
مهندسی شیمی
بیو مهندسی (مهندسی زیستی)
پیش نمایش صفحه اول مقاله
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چکیده انگلیسی
Scaffolds comprising poly(lactic acid) and nano-hydroxyapatite (HA) were prepared using the solvent-casting/salt-leaching technique. NaCl was used as the leaching agent. Nano-sized HA was synthesized by a hydrothermal method at 170 °C and autogenous pressure. High-resolution TEM imaging revealed that the HA particles were ellipsoidal-shaped with needle-like morphologies. The particles had an average size of approximately 25 nm in width and 150 nm in length with aspect ratios ranging from 6 to 8. As the HA content increased in the scaffold from 0 to 50 wt%, the compression modulus of the scaffolds increased from 4.72 ± 1.2 to 9.87 ± 1.8 MPa, while the yield strength from 0.29 ± 0.03 to 0.44 ± 0.01 MPa. Such polymeric scaffolds should be suitable materials for non-load sharing tissue-engineering applications.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Acta Biomaterialia - Volume 1, Issue 6, November 2005, Pages 653-662
Journal: Acta Biomaterialia - Volume 1, Issue 6, November 2005, Pages 653-662
نویسندگان
Chandrasekhar R. Kothapalli, Montgomery T. Shaw, Mei Wei,