کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
10218402 1687165 2018 17 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Thrombocytopenia in Pregnancy: Mechanisms and Management
ترجمه فارسی عنوان
ترومبوسیتوپنی در بارداری: مکانیسم و ​​مدیریت
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی هماتولوژی
چکیده انگلیسی
Thrombocytopenia is a common hematologic issue encountered by obstetricians and hematologists, detected in about 10% of all pregnancies. In the vast majority of cases, the thrombocytopenia will be attributed to gestational thrombocytopenia (GT), where the thrombocytopenia is mild, does not necessitate active management, and does not introduce maternal or fetal bleeding risk. Although GT is common, the specific mechanism responsible for it is not known with certainty, and therefore, differentiating it from other causes of thrombocytopenia can be challenging. Previously proposed explanations for GT suggest that a decrease in platelet count is universal in pregnancy, and women diagnosed with GT are simply those with a baseline platelet count on the lower end of normal range. This concept is challenged in this review, and a possible mechanism for GT is proposed. Additionally, a framework for approaching the diagnosis and management of thrombocytopenia in pregnancy is presented.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Transfusion Medicine Reviews - Volume 32, Issue 4, October 2018, Pages 225-229
نویسندگان
,