Abstract Next Subvolume Method: A logical process-based approach for spatial stochastic simulation of chemical reactions

► We present the ANSM to decouple the Next Subvolume Method from sequential execution. ► We present the model representation and the abstract execution semantics for ANSM. ► The justification of the ANSM is presented. ► Parallel execution with ANSM achieves considerable speedup. ► The control of optimism is important to a scalable parallel stochastic simulation.