کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
10233569 42757 2005 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Lipase-catalyzed production of novel hydroxylated fatty amides in organic solvent
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی بیو مهندسی (مهندسی زیستی)
پیش نمایش صفحه اول مقاله
Lipase-catalyzed production of novel hydroxylated fatty amides in organic solvent
چکیده انگلیسی
Pseudozyma (Candida) antarctica lipase B is known to catalyze the direct amidation of carboxylic acids with ammonia in organic solvents. We tested this system for production of primary fatty amides from hydroxy fatty acids including the naturally occurring mono-hydroxy fatty acids, ricinoleic acid (RA) and lesquerolic acid (LQA) and the novel multihydroxy fatty acids, 7,10-dihydroxy-8(E)-octadecenoic acid (DOD) and 7,10,12-trihydroxy-8(E)-octadecenoic acid (TOD). Reactions were performed at temperatures up to 55 °C. Ricinoleic acid and lesquerolic acid were transformed at initial rates comparable to or better than that of oleic acid, a non-hydroxylated substrate. Transformation percentage at 7 days was better than 95% for all substrates except TOD (93.9%). At 55 °C, most reactions approached completion within 1 day. The primary amides of LQA, DOD, and TOD are novel compounds having melting points of 73, 105, and 100 °C, respectively.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Enzyme and Microbial Technology - Volume 37, Issue 1, 1 June 2005, Pages 126-130
نویسندگان
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