Enhancement of extraction efficiency of paclitaxel from biomass using ionic liquid-methanol co-solvents under acidic conditions

- An ionic liquid (IL)-based extraction process was developed for paclitaxel.
- Acid hydrolysis with IL broke down a glycosidic bond of glycoside.
- The paclitaxel recovery was increased by the cleavage of glycoside.
- The efficiency of IL-based extraction process was enhanced.