Characterization of a novel laccase from the isolated Coltricia perennis and its application to detoxification of biomass

► We isolate and identify a high laccase-producing strain, Coltricia perennis. ► The purified laccase (Cplac) from C. perennis shows a higher activity than any other reported laccase. ► High stability and catalytic efficiency of Cplac suggest its suitability for industrial applications. ► Cplac detoxifies phenolic compounds in rice straw more efficiently than Novozym 51003.