کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
10254983 161483 2015 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Superficially located enlarged lymphoid follicles characterise nodular gastritis
ترجمه فارسی عنوان
غدد لنفاوی بزرگ به طور گسترده ای در معرض گاستریت ندولیک قرار می گیرند
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی پزشکی قانونی
چکیده انگلیسی
Nodular gastritis is a form of chronic Helicobacter pylori gastritis affecting the gastric antrum and characterised endoscopically by the presence of small nodular lesions resembling gooseflesh. It is generally accepted that hyper-plasia of lymphoid follicles histologically characterises nodular gastritis; however, quantitative analysis in support of this hypothesis has not been reported. Our goal was to determine whether nodular gastritis is characterised by lymphoid follicle hyperplasia. The number, size, and location of lymphoid follicles in nodular gastritis were determined and those properties compared to samples of atrophic gastritis. The percentages of high endothelial venule (HEV)-like vessels were also evaluated. The number of lymphoid follicles was comparable between nodular and atrophic gastritis; however, follicle size in nodular gastritis was significantly greater than that seen in atrophic gastritis. Moreover, lymphoid follicles in nodular gastritis were positioned more superficially than were those in atrophic gastritis. The percentage of MECA-79+ HEV-like vessels was greater in areas with gooseflesh-like lesions in nodular versus atrophic gastritis. Superficially located hyper-plastic lymphoid follicles characterise nodular gastritis, and these follicles correspond to gooseflesh-like nodular lesions observed endoscopically. These observations suggest that MECA-79+ HEV-like vessels could play at least a partial role in the pathogenesis of nodular gastritis.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Pathology - Volume 47, Issue 1, January 2015, Pages 38-44
نویسندگان
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