کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10255271 | 161555 | 2005 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
The prevalence of inherited thrombophilias in a Caucasian Australian population
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
پزشکی قانونی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: The prevalence of inherited thrombophilias in a Caucasian Australian population The prevalence of inherited thrombophilias in a Caucasian Australian population](/preview/png/10255271.png)
چکیده انگلیسی
The birth prevalences of heterozygosity and homozygosity for the four thrombophilic polymorphisms were: factor V Leiden 9.5% and 0.7%, prothrombin gene 4.1% and 0.2%, MTHFR C677T 37.3% and 12.4%, and MTHFR A1298C 38.3% and 11.8%, respectively. Compound heterozygosity for MTHFR C677T and A1298C was seen in 16.6% of the population. Overall, 64.2% and 24.5% of the population studied were homozygous and heterozygous, respectively, for at least one of the four polymorphisms studied. Conclusion: Inherited thrombophilic polymorphisms are common in the Caucasian Australian population. Knowledge of the background prevalence of these polymorphisms will allow further study of their associations in future disease research.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Pathology - Volume 37, Issue 2, April 2005, Pages 160-163
Journal: Pathology - Volume 37, Issue 2, April 2005, Pages 160-163
نویسندگان
South Australian Cerebral Palsy Research Group South Australian Cerebral Palsy Research Group, Catherine S. Gibson, Alastair H. MacLennan, Zbigniew Rudzki, William M. Hague, Eric A. Haan, Phillipa Sharpe, Kevin Priest, Annabelle Chan, Gustaaf A. Dekker,