کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10303414 | 545506 | 2011 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Sex differences in cognition among persons with schizophrenia and healthy first-degree relatives
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
روانپزشکی بیولوژیکی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Sex differences in cognition among persons with schizophrenia and healthy first-degree relatives Sex differences in cognition among persons with schizophrenia and healthy first-degree relatives](/preview/png/10303414.png)
چکیده انگلیسی
Previous research suggests differences between women and men in the clinical features of schizophrenia, but studies examining sex differences in neuropsychological functioning have reached inconsistent results. In the present study, sex differences in cognition and clinical features were investigated in population-based samples of participants with schizophrenia (n = 218), their healthy first-degree relatives (n = 438) and controls (n = 123). Sex differences in illness features were small; nevertheless, women with schizophrenia had less negative symptoms and lived independently more often than men. The schizophrenia group had impairments in all studied neuropsychological domains, and the relatives were impaired in processing speed and set-shifting. In all groups, women performed better than men in processing speed, set-shifting and verbal episodic memory, whereas men outperformed women in visual working memory. The group-by-sex interaction was significant in two variables: women outperformed men in the relatives group in immediate verbal reproduction and in the use of semantic clustering as a learning strategy, while there was no sex difference in the schizophrenia group. In conclusion, sex differences in cognition are mostly similar in schizophrenia to those among controls, despite sex differences in illness features. The preservation of sex differences also in first-degree relatives supports the conclusion.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Psychiatry Research - Volume 188, Issue 1, 30 June 2011, Pages 7-12
Journal: Psychiatry Research - Volume 188, Issue 1, 30 June 2011, Pages 7-12
نویسندگان
Minna Torniainen, Jaana Suvisaari, Timo Partonen, Anu E. Castaneda, Annamaria Kuha, Jonna Perälä, Samuli Saarni, Jouko Lönnqvist, Annamari Tuulio-Henriksson,