کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10317859 | 621934 | 2013 | 12 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Growth hormone combined with child-specific motor training improves motor development in infants with Prader-Willi syndrome: A randomized controlled trial
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کلمات کلیدی
PWSBSID-IIBayley Scales of Infant Development 2nd EditionMLRAGMFMAlberta Infant Motor Scale - آلبرتا نوزاد مقیاس موتورPhysical training - آموزش فیزیکیGross motor function measure - اندازه گیری عملکرد ناخالصAIMS - اهدافMotor development - توسعه موتورPrader-Willi syndrome - سندرم Prader-WilliInfants - نوزادGrowth hormone - هورمون رشد
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
علوم اعصاب رفتاری
پیش نمایش صفحه اول مقاله

چکیده انگلیسی
Although severe motor problems in infants with Prader-Willi syndrome (PWS) are striking, motor development has never been studied longitudinally and the results of growth hormone (GH) treatment on motor development are contradictory. The authors studied whether GH treatment can enhance the effect of physical training on motor development in infants with PWS. Twenty-two infants were followed for two years during a randomized controlled trial. The treatment and control groups began GH after baseline or following a control period, respectively. Both groups followed a child-specific physical training program. Motor performance was measured every three months. Multi-level regression analysis revealed that motor development differed significantly between infants (p < .001), and this could be partially explained by baseline motor developmental level (p < .01). GH treatment enhanced the effects of child-specific physical training on both motor developmental rate and motor developmental potential. Moreover, this effect was more pronounced when GH treatment was initiated at a younger age.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Research in Developmental Disabilities - Volume 34, Issue 10, October 2013, Pages 3092-3103
Journal: Research in Developmental Disabilities - Volume 34, Issue 10, October 2013, Pages 3092-3103
نویسندگان
Linda Reus, Ben J. Pelzer, Barto J. Otten, Elbrich P.C. Siemensma, Janielle A.A.E.M. van Alfen-van der Velden, Dederieke A.M. Festen, Anita C.S. Hokken-Koelega, Maria W.G. Nijhuis-van der Sanden,