کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10374855 | 879937 | 2011 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Preparation, characterization and pharmacokinetics of enrofloxacin-loaded solid lipid nanoparticles: Influences of fatty acids
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
مهندسی شیمی
شیمی کلوئیدی و سطحی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Preparation, characterization and pharmacokinetics of enrofloxacin-loaded solid lipid nanoparticles: Influences of fatty acids Preparation, characterization and pharmacokinetics of enrofloxacin-loaded solid lipid nanoparticles: Influences of fatty acids](/preview/png/10374855.png)
چکیده انگلیسی
ⶠThe hot homogenization and ultrasonication method are feasible for preparation of enrofloxacin-loaded fatty acid SLN. ⶠThe SLN have sustained release effects and can enhance the pharmacological activity of enrofloxacin. ⶠThe fatty acids significantly affected the physicochemical characteristics and pharmacological activity of enrofloxacin-loaded SLN. ⶠLonger carbon chain length of fatty acid resulted in higher drug incorporation and more pronounced sustained release in vitro. ⶠThe enhancement of bioavailability and systematic circulation time of the drug were significantly increased with the decrease of carbon chain length.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Colloids and Surfaces B: Biointerfaces - Volume 83, Issue 2, 1 April 2011, Pages 382-387
Journal: Colloids and Surfaces B: Biointerfaces - Volume 83, Issue 2, 1 April 2011, Pages 382-387
نویسندگان
Shuyu Xie, Luyan Zhu, Zhao Dong, Xiaofang Wang, Yan Wang, Xihe Li, WenZhong Zhou,