Human plasma protein adsorption onto dextranized surfaces: A two-dimensional electrophoresis and mass spectrometry study

▶ We assessed human plasma protein adsorption onto solid substrates. ▶ Methods included two-dimensional gel electrophoresis and mass spectrometry. ▶ Surfaces were SiO2, dextranized SiO2, polyurethane, dextranized polyurethane. ▶ Dextranization significantly inhibits adsorption of multiple proteins.