Treatment of tetracycline antibiotics by laccase in the presence of 1-hydroxybenzotriazole

► Treatment of tetracycline antibiotics by laccase in the presence of 1-hydroxybenzotriazole (HBT). ► Tetracycline antibiotics are effectively eliminated by treatment with the laccase-HBT system. ► This system completely removes the bacterial and algal growth inhibition of tetracycline antibiotics.